#RNAylation
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s-lab.bsky.social
Many thanks to Katharina Höfer @hoeferlab.bsky.social for giving an inspiring presentation about RNAylation at our annual "Early-Career Microbiologists Symposium" @johninnescentre.bsky.social. Many thanks also to #EMBO @embo.org for supporting this "Young Investigator Seminar".
September 16, 2025 at 6:45 AM
mpimicrobiomarburg.bsky.social
Congratulations🎉 @maiktungsten.bsky.social for receiving the Friedrich Hirzebruch-Promotionspreis 2025! 🏆
Maik`s groundbreaking work at @hoeferlab.bsky.social has paved the way for new insights into phage-host interactions and epitranscriptomics ! #phages #RNAylation
hoeferlab.bsky.social Höfer Lab @hoeferlab.bsky.social · Jan 23
Huuuuuuuuge congratulations to Maik Wolfram-Schauerte for receiving this year's Friedrich Hirzebruch PhD Prize from the Studienstiftung des deutschen Volkes! So well deserved! #ProudPI @mpimicrobiomarburg.bsky.social @unimarburg.bsky.social @synmikro.bsky.social
maiktungsten.bsky.social Maik Wolfram-Schauerte @maiktungsten.bsky.social · Jan 23
I am truly honored to receive this year's Friedrich Hirzebruch PhD prize for my interdisciplinary work on phage-host interactions and NAD-capped RNA. Huge thanks to @hoeferlab.bsky.social, @spp2330.bsky.social, Studienstiftung and Joachim Herz Foundation!
www.studienstiftung.de/auszeichnung...
January 24, 2025 at 9:50 AM
uwmadisonrna.bsky.social
I don't think it is the weirdest... lactylation? RNAylation? Hypusinylation? Dipthimidylation?
November 18, 2024 at 3:01 PM
biorxiv-bioeng.bsky.social
Engineering site-specific nucleic acid-protein conjugates by utilizing a natural RNAylation reaction https://www.biorxiv.org/content/10.1101/2025.07.11.664405v1
July 17, 2025 at 3:46 AM
phagepapers.bsky.social
Bridging the gap: RNAylation conjugates RNAs to proteins.

DOI: 10.1016/j.bbamcr.2024.119826

https://pubmed.ncbi.nlm.nih.gov/39182583/
Bridging the gap: RNAylation conjugates RNAs to proteins - PubMed
In nature, the majority of known RNA-protein interactions are transient. Our recent study has depicted a novel mechanism known as RNAylation, which covalently links proteins and RNAs. This novel modification bridges the realms of RNA and protein modifications. This review specifically explores RNAyl …
pubmed.ncbi.nlm.nih.gov
December 6, 2024 at 9:37 AM
grnfluoresceblg.bsky.social
Posters 221, 142
plaschka lab
julius brennecke on mRNA export looks cool
Poster 285 katharina Hoefer on RNAylation for RNA therapeutics looks very interesting
October 24, 2024 at 12:39 PM
ameliacervera.eurosky.social
A viral ADP-ribosyltransferase attaches RNA chains to host proteins (2023).
www.nature.com/articles/s41...
a, The mechanism of ADP-ribosylation for Arg. Initially, the N-glycosidic bond between the ribose and nicotinamide is destabilized by a Glu residue of an ART. This leads to the formation of an oxocarbenium ion of ADPr, with nicotinamide as the leaving group. This electrophilic ion is attacked by a nucleophilic Arg residue of the acceptor protein after Glu-mediated proton abstraction, leading to the formation of an N-glycosidic bond50. b, Our proposed RNAylation-reaction mechanism. In a similar way to ADP-ribosylation in the presence of NAD, we propose that ARTs might use NAD–RNA to catalyse an RNAylation reaction, thereby covalently attaching an RNA to an acceptor protein. Red, nicotinamide riboside of NAD and NAD-RNA; blue, catalytic residues of the ART; purple, nucleophilic Arg residue of the acceptor protein.
October 10, 2023 at 1:42 PM
biorxivpreprint.bsky.social
Engineering site-specific nucleic acid-protein conjugates by utilizing a natural RNAylation reaction https://www.biorxiv.org/content/10.1101/2025.07.11.664405v1
July 17, 2025 at 3:46 AM