Memory-safe high-performance sequence mapping with rammap https://www.biorxiv.org/content/10.64898/2026.05.26.726289v1
May 30, 2026 at 1:11 AM
Memory-safe high-performance sequence mapping with rammap https://www.biorxiv.org/content/10.64898/2026.05.26.726289v1
Jeremy Wang developed rammap, a minimap2 rewrite in Rust. It achieves comparable or better performance than minimap2 and produces identical output to minimap2. During rewrite, Jeremy found two long-existing bugs in minimap2 which are fixed in v2.31. www.biorxiv.org/content/10.6...
www.biorxiv.org
May 30, 2026 at 3:04 PM
Jeremy Wang developed rammap, a minimap2 rewrite in Rust. It achieves comparable or better performance than minimap2 and produces identical output to minimap2. During rewrite, Jeremy found two long-existing bugs in minimap2 which are fixed in v2.31. www.biorxiv.org/content/10.6...
The recently-released rammap from Jeremy Wang and @lh3lh3.bsky.social is, indeed, looking like a strong contender to replace minimap2-rs in oarfish!
June 3, 2026 at 11:42 PM
The recently-released rammap from Jeremy Wang and @lh3lh3.bsky.social is, indeed, looking like a strong contender to replace minimap2-rs in oarfish!
I have tried:
* task manager
* process explorer
* resource monitor
* rammap
None of them show there the missing memory is going.
* task manager
* process explorer
* resource monitor
* rammap
None of them show there the missing memory is going.
April 5, 2025 at 6:37 PM
I have tried:
* task manager
* process explorer
* resource monitor
* rammap
None of them show there the missing memory is going.
* task manager
* process explorer
* resource monitor
* rammap
None of them show there the missing memory is going.
I think I might have figured out the memory issue for rammap @niema.net, github.com/jwanglab/ram.... Jeremey has been incredibly responsive, so hopefully this lands soon!
dp: cap the per-thread DP scratch cache to bound peak RSS by rob-p · Pull Request #9 · jwanglab/rammap
Problem
The thread-local DP_MEM_CACHE (rammap-core/src/align/dp/common.rs) keeps each worker thread's high-water-mark DP scratch buffer alive for the lifetime of the run, to avoid repeated larg...
github.com
June 6, 2026 at 12:42 PM
I think I might have figured out the memory issue for rammap @niema.net, github.com/jwanglab/ram.... Jeremey has been incredibly responsive, so hopefully this lands soon!
I now have (and hope to release soon) a version of oarfish that swaps out minimap2-rs for rammap (it's generally faster & more RAM friendly). This is, IMO, an example of generative AI rapidly accelerating software dev in a good way. The integration would have taken a lot more time by hand!
June 5, 2026 at 7:00 PM
I now have (and hope to release soon) a version of oarfish that swaps out minimap2-rs for rammap (it's generally faster & more RAM friendly). This is, IMO, an example of generative AI rapidly accelerating software dev in a good way. The integration would have taken a lot more time by hand!
Why rammap can be faster: 1) AVX2/AVX512 for base alignment; 2) better memory management (minimap2 is okay but not the best); 3) more sophisticated multi-threading model with rayon; 4) SIMD-based chaining learned from mm2-fast.
May 30, 2026 at 5:05 PM
Why rammap can be faster: 1) AVX2/AVX512 for base alignment; 2) better memory management (minimap2 is okay but not the best); 3) more sophisticated multi-threading model with rayon; 4) SIMD-based chaining learned from mm2-fast.
Support for rammap added in ViralMSA v1.1.48! On my 8-core laptop, on a SARS-CoV-2 dataset with 20,000 genomes, compared to Minimap2, runtime was 29.37s vs 32.96s (~10% faster), and peak memory was 1,853,936 KB vs 876,800 KB (>2x memory) github.com/niemasd/Vira...
May 30, 2026 at 2:07 PM
Support for rammap added in ViralMSA v1.1.48! On my 8-core laptop, on a SARS-CoV-2 dataset with 20,000 genomes, compared to Minimap2, runtime was 29.37s vs 32.96s (~10% faster), and peak memory was 1,853,936 KB vs 876,800 KB (>2x memory) github.com/niemasd/Vira...
have you tried using rammap? learn.microsoft.com/en-us/sysint...
RAMMap - Sysinternals
An advanced physical memory usage analysis utility that presents usage information in different ways on its several different tabs.
learn.microsoft.com
September 9, 2024 at 4:18 AM
have you tried using rammap? learn.microsoft.com/en-us/sysint...
listent for macOS, ZoomIt, Sysmon, DebugView, NotMyFault, Procmon for Linux, and RAMMap | Sysinternals blog
buff.ly/4mb7E9D
#devtools #windows #linux #utilities #sysinternals #zoomit #procmon
buff.ly/4mb7E9D
#devtools #windows #linux #utilities #sysinternals #zoomit #procmon
listent for macOS, ZoomIt, Sysmon, DebugView, NotMyFault, Procmon for Linux, and RAMMap | Microsoft Community Hub
listent 1.0 for macOS listent is a macOS command-line tool to discover and list code signing entitlements for executable binaries. It supports static...
buff.ly
March 27, 2026 at 4:01 PM
listent for macOS, ZoomIt, Sysmon, DebugView, NotMyFault, Procmon for Linux, and RAMMap | Sysinternals blog
buff.ly/4mb7E9D
#devtools #windows #linux #utilities #sysinternals #zoomit #procmon
buff.ly/4mb7E9D
#devtools #windows #linux #utilities #sysinternals #zoomit #procmon
We're excited to release ZoomIt with a video trim editor, Sysmon for Linux with EBPF events, and DebugView, RAMMap, RDCMan with bug fixes!
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Sysinternals - Sysinternals
Library, learning resources, downloads, support, and community. Evaluate and find out how to install, deploy, and maintain Windows with Sysinternals utilities.
sysinternals.com
February 4, 2026 at 8:49 PM
We're excited to release ZoomIt with a video trim editor, Sysmon for Linux with EBPF events, and DebugView, RAMMap, RDCMan with bug fixes!
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
- YouTube
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
youtu.be
July 22, 2025 at 10:00 AM
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12
techcommunity.microsoft.com/blog/sysinte...
#sysinternals #devtools #windows #linux #utilities
techcommunity.microsoft.com/blog/sysinte...
#sysinternals #devtools #windows #linux #utilities
ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12 | Microsoft Community Hub
ZoomIt v10.0 This update to ZoomIt, a screen magnification and annotation tool, adds a video clip editor for trimming recordings before saving them and...
techcommunity.microsoft.com
February 5, 2026 at 3:00 PM
ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12
techcommunity.microsoft.com/blog/sysinte...
#sysinternals #devtools #windows #linux #utilities
techcommunity.microsoft.com/blog/sysinte...
#sysinternals #devtools #windows #linux #utilities
📢 New tool: listent for macOS, new features: ZoomIt (panoramic screenshots!), Sysmon, DebugView, and NotMyFault, fixes: Procmon for Linux, RAMMap!
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Sysinternals - Sysinternals
Library, learning resources, downloads, support, and community. Evaluate and find out how to install, deploy, and maintain Windows with Sysinternals utilities.
sysinternals.com
March 26, 2026 at 9:07 PM
📢 New tool: listent for macOS, new features: ZoomIt (panoramic screenshots!), Sysmon, DebugView, and NotMyFault, fixes: Procmon for Linux, RAMMap!
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
Get the tools at sysinternals.com.
See what's new on the Sysinternals Blog: techcommunity.microsoft.com/blog/sysinte...
i haven't had any issues with memory leaks yet (tm). the worst OS for memory leaks imho is Windows. i usually have to use rammap (or reboot) to fix it in Windows lol
but any issue with macOS: no, they cannot fix it, that money is allocated to pay for their UNIX certification
but any issue with macOS: no, they cannot fix it, that money is allocated to pay for their UNIX certification
November 19, 2024 at 4:53 PM
i haven't had any issues with memory leaks yet (tm). the worst OS for memory leaks imho is Windows. i usually have to use rammap (or reboot) to fix it in Windows lol
but any issue with macOS: no, they cannot fix it, that money is allocated to pay for their UNIX certification
but any issue with macOS: no, they cannot fix it, that money is allocated to pay for their UNIX certification
Boost your PC performance! 🚀 Learn how to clear the RAM cache on Windows 10/11 with RamMap in just a few simple steps. Free up memory & improve speed! 💻 #Windows11 #PCPerformance #RamMap #TechHacks
youtu.be/LvSXGEmfk1Q
youtu.be/LvSXGEmfk1Q
How to Clear the RAM cache on Windows 10/11 🚀
YouTube video by XEEDROID
youtu.be
January 8, 2025 at 6:41 AM
Boost your PC performance! 🚀 Learn how to clear the RAM cache on Windows 10/11 with RamMap in just a few simple steps. Free up memory & improve speed! 💻 #Windows11 #PCPerformance #RamMap #TechHacks
youtu.be/LvSXGEmfk1Q
youtu.be/LvSXGEmfk1Q
"ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12" buff.ly/MXlpiNr #Microsoft #techcommunity
ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12 | Microsoft Community Hub
ZoomIt v10.0
This update to ZoomIt, a screen magnification and annotation tool, adds a video clip editor for trimming recordings before saving them and...
buff.ly
February 4, 2026 at 8:46 PM
"ZoomIt v10.0, Sysmon 1.5 for Linux, Sigcheck v2.91, RAMMap v1.62, and RDCMan v3.12" buff.ly/MXlpiNr #Microsoft #techcommunity
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
- YouTube
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
youtu.be
September 22, 2025 at 3:30 PM
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
The learn.microsoft.com/en-us/sysint... tool helped me find the culprit back in the day - backup agent grabbed a lot of memory and never released it when done. Every night. Sure enough, an update was available.
RAMMap - Sysinternals
An advanced physical memory usage analysis utility that presents usage information in different ways on its several different tabs.
learn.microsoft.com
February 27, 2025 at 9:17 AM
The learn.microsoft.com/en-us/sysint... tool helped me find the culprit back in the day - backup agent grabbed a lot of memory and never released it when done. Every night. Sure enough, an update was available.
I've made rammap the new ViralMSA default because it's memory-safe, it was slightly faster, and even at 2x memory usage, it's still reasonable for viral genomes (still well within my laptop's available memory), but I was surprised by how much more memory-intensive it was
May 30, 2026 at 2:10 PM
I've made rammap the new ViralMSA default because it's memory-safe, it was slightly faster, and even at 2x memory usage, it's still reasonable for viral genomes (still well within my laptop's available memory), but I was surprised by how much more memory-intensive it was
After a wild ride of looking into why PC feels so sluggish (UIforETW, RamMap, WinObj, FindZombieHandles) I find this thread from just two days ago and yep, it's the AMD driver.
I have unused iGPU and it still caused 10k+ processes to leak.
ETW showed system struggling to walk page tables.
I have unused iGPU and it still caused 10k+ processes to leak.
ETW showed system struggling to walk page tables.
February 8, 2026 at 9:01 PM
After a wild ride of looking into why PC feels so sluggish (UIforETW, RamMap, WinObj, FindZombieHandles) I find this thread from just two days ago and yep, it's the AMD driver.
I have unused iGPU and it still caused 10k+ processes to leak.
ETW showed system struggling to walk page tables.
I have unused iGPU and it still caused 10k+ processes to leak.
ETW showed system struggling to walk page tables.
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
- YouTube
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
youtu.be
March 11, 2026 at 8:00 AM
🖥️ “Big Brother is Watching!” by Bartek Bielawski taught how to troubleshoot client machines remotely using #PowerShell without disrupting users:
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
🧰 #Sysinternals (Handle, Procmon, RAMMap)
📡 #pktmon > netsh
🧪 Smart prep = zero friction
🎟️ psconf.eu
#RemoteSupport #PSConfEU
Windowsが病気にかかってしまったので通知画面出すとたまにメモリ全部(64GB)食われるようになった。
RAMMapを見るとSharable Memoryがとんでもないサイズに。
何が原因かわからないがとりあえずアプリ全部落として暫く経つと直る。
RAMMapを見るとSharable Memoryがとんでもないサイズに。
何が原因かわからないがとりあえずアプリ全部落として暫く経つと直る。
December 17, 2024 at 6:01 AM
Windowsが病気にかかってしまったので通知画面出すとたまにメモリ全部(64GB)食われるようになった。
RAMMapを見るとSharable Memoryがとんでもないサイズに。
何が原因かわからないがとりあえずアプリ全部落として暫く経つと直る。
RAMMapを見るとSharable Memoryがとんでもないサイズに。
何が原因かわからないがとりあえずアプリ全部落として暫く経つと直る。