Scientists in the @alushinlab.bsky.social have figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for metastasis. #RockefellerScience
bit.ly/3PKErmA
bit.ly/3PKErmA
January 21, 2025 at 3:20 PM
Scientists in the @alushinlab.bsky.social have figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for metastasis. #RockefellerScience
bit.ly/3PKErmA
bit.ly/3PKErmA
A new study in ants from @danielkronauer.bsky.social reveals a previously unknown mechanism that ensures that each olfactory neuron expresses only one odorant receptor, with broad implications for the study of gene regulation. #RockefellerScience
https://bit.ly/4pwPFLY
https://bit.ly/4pwPFLY
September 19, 2025 at 3:30 PM
A new study in ants from @danielkronauer.bsky.social reveals a previously unknown mechanism that ensures that each olfactory neuron expresses only one odorant receptor, with broad implications for the study of gene regulation. #RockefellerScience
https://bit.ly/4pwPFLY
https://bit.ly/4pwPFLY
A study from @victora.bsky.social and @danmucida.bsky.social in @science.org reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases. #RockefellerScience bit.ly/4hyS18b
January 28, 2025 at 8:23 PM
A study from @victora.bsky.social and @danmucida.bsky.social in @science.org reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases. #RockefellerScience bit.ly/4hyS18b
New imaging from @victora.bsky.social's lab reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. #RockefellerScience
New mechanism behind adaptive immunity revealed. It could impact how we design vaccines. - News
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted...
www.rockefeller.edu
March 19, 2025 at 6:40 PM
New imaging from @victora.bsky.social's lab reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. #RockefellerScience
New research from @danielkronauer.bsky.social's lab in @pnas.org sheds light on how a young ant’s future is determined by genetics and the environment, finding that genes not only influence size, they change what a given size means for the colony. #RockefellerScience
How ant queens are made - News
Daniel Kronauer’s research on an unusual ant species illuminates the biochemistry and genetics behind complex social behavior—and potentially offers clues to the evolution of our own social brains.
www.rockefeller.edu
July 22, 2025 at 7:07 PM
New research from @danielkronauer.bsky.social's lab in @pnas.org sheds light on how a young ant’s future is determined by genetics and the environment, finding that genes not only influence size, they change what a given size means for the colony. #RockefellerScience
Researchers in the #FunabikiLab have devised a way to visualize molecules that are very rare, very small, or hard to produce naturally—including some viruses.
@elife.bsky.social #RockefellerScience
@elife.bsky.social #RockefellerScience
New method dramatically improves cryo-EM’s imaging capabilities - News
Researchers have devised a way to visualize molecules that are very rare, very small, or hard to produce naturally, including viruses.
www.rockefeller.edu
May 20, 2025 at 3:09 PM
Researchers in the #FunabikiLab have devised a way to visualize molecules that are very rare, very small, or hard to produce naturally—including some viruses.
@elife.bsky.social #RockefellerScience
@elife.bsky.social #RockefellerScience
A study from @danmucida.bsky.social and @victora.bsky.social showed how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of #foodallergies. #RockefellerScience #YearInReview
🔗: https://bit.ly/4hyS18b
🔗: https://bit.ly/4hyS18b
December 31, 2025 at 3:24 PM
A study from @danmucida.bsky.social and @victora.bsky.social showed how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of #foodallergies. #RockefellerScience #YearInReview
🔗: https://bit.ly/4hyS18b
🔗: https://bit.ly/4hyS18b
Rockefeller's Li Zhao spent nearly a decade cataloguing evolutionarily young genes. This year, her lab demonstrated how these new genes are regulated and expressed. #RockefellerScience #YearInReview
🔗: https://bit.ly/4jdvwb8
🔗: https://bit.ly/4jdvwb8
December 27, 2025 at 8:41 PM
Rockefeller's Li Zhao spent nearly a decade cataloguing evolutionarily young genes. This year, her lab demonstrated how these new genes are regulated and expressed. #RockefellerScience #YearInReview
🔗: https://bit.ly/4jdvwb8
🔗: https://bit.ly/4jdvwb8
A new paper from the #MacKinnonLab in @pnas.org finds that while Kv2.1 and EAG1 are from distinct architectural classes of voltage-dependent ion channels, the way the voltage sensors gate their pores is very similar. #RockefellerScience
Electric field–induced pore constriction in the human Kv2.1 channel | PNAS
Gating in voltage-dependent ion channels is regulated by the transmembrane voltage.
This form of regulation is enabled by voltage-sensing domains (...
www.pnas.org
May 19, 2025 at 3:56 PM
A new paper from the #MacKinnonLab in @pnas.org finds that while Kv2.1 and EAG1 are from distinct architectural classes of voltage-dependent ion channels, the way the voltage sensors gate their pores is very similar. #RockefellerScience
Now out in @natbiotech.nature.com: Newly identified compounds from the #BradyLab appear effective against drug-resistant bacteria. The technique used to reveal them could uncover many more antibiotics, as well as help illuminate a previously hidden microbial world. #RockefellerScience
Hundreds of new bacteria, and two potential antibiotics, found in soil - News
Most bacteria cannot be cultured in the lab—and that’s been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines r...
www.rockefeller.edu
September 12, 2025 at 6:09 PM
Now out in @natbiotech.nature.com: Newly identified compounds from the #BradyLab appear effective against drug-resistant bacteria. The technique used to reveal them could uncover many more antibiotics, as well as help illuminate a previously hidden microbial world. #RockefellerScience
New research from #DarstLab in @naturesmb.bsky.social reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. #RockefellerScience
bit.ly/4gZ5kir
bit.ly/4gZ5kir
January 14, 2025 at 2:41 PM
New research from #DarstLab in @naturesmb.bsky.social reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. #RockefellerScience
bit.ly/4gZ5kir
bit.ly/4gZ5kir
A new method from @hirofunabiki.bsky.social dramatically improved cryo-EM’s imaging capabilities, enabling visualization of molecules that are very rare, very small, or hard to produce naturally—including some viruses. #RockefellerScience #YearInReview
🔗: https://bit.ly/4awR4gv
🔗: https://bit.ly/4awR4gv
December 29, 2025 at 9:40 PM
A new method from @hirofunabiki.bsky.social dramatically improved cryo-EM’s imaging capabilities, enabling visualization of molecules that are very rare, very small, or hard to produce naturally—including some viruses. #RockefellerScience #YearInReview
🔗: https://bit.ly/4awR4gv
🔗: https://bit.ly/4awR4gv
Treatments for autoimmune diseases have big shortcomings, including high cost and supply shortages. A alternative developed this year from the #RavetchLab achieves the same effectiveness at a fraction of the dose. #RockefellerScience #YearInReview
🔗: https://bit.ly/3HFdsbs
🔗: https://bit.ly/3HFdsbs
December 27, 2025 at 1:42 PM
Treatments for autoimmune diseases have big shortcomings, including high cost and supply shortages. A alternative developed this year from the #RavetchLab achieves the same effectiveness at a fraction of the dose. #RockefellerScience #YearInReview
🔗: https://bit.ly/3HFdsbs
🔗: https://bit.ly/3HFdsbs
Thanks for recapping the most intriguing #RockefellerScience stories of 2025 with us, Happy New Year! 👩🏽🔬 🥂 🦠 🎉 🧬
See the full 2025 #YearInReview here: https://bit.ly/44LtGrW
See the full 2025 #YearInReview here: https://bit.ly/44LtGrW
January 1, 2026 at 5:01 AM
Thanks for recapping the most intriguing #RockefellerScience stories of 2025 with us, Happy New Year! 👩🏽🔬 🥂 🦠 🎉 🧬
See the full 2025 #YearInReview here: https://bit.ly/44LtGrW
See the full 2025 #YearInReview here: https://bit.ly/44LtGrW
Scientists in the @alushinlab.bsky.social figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for #metastasis. #RockefellerScience #YearInReview
🔗: https://bit.ly/3PKErmA
🔗: https://bit.ly/3PKErmA
December 31, 2025 at 10:30 PM
Scientists in the @alushinlab.bsky.social figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for #metastasis. #RockefellerScience #YearInReview
🔗: https://bit.ly/3PKErmA
🔗: https://bit.ly/3PKErmA
New findings from the #GilbertLab in @pnas.org suggest neurons have much more functional dexterity than scientists previously realized. #RockefellerScience
Our ability to recognize objects depends on prior experience - News
New findings suggest neurons have much more functional dexterity than scientists previously realized.
www.rockefeller.edu
May 2, 2025 at 3:19 PM
New findings from the #GilbertLab in @pnas.org suggest neurons have much more functional dexterity than scientists previously realized. #RockefellerScience
Shortly before his death this year, James Hudspeth achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience #YearInReview
🔗: https://bit.ly/49oaOlo
🔗: https://bit.ly/49oaOlo
December 26, 2025 at 11:30 AM
Shortly before his death this year, James Hudspeth achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience #YearInReview
🔗: https://bit.ly/49oaOlo
🔗: https://bit.ly/49oaOlo
Shortly before his death last month, James Hudspeth and his team achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience
Researchers keep a mammalian cochlea alive outside the body for the first time - News
The technological breakthrough may improve our understanding of the cellular mechanisms behind hearing loss.
www.rockefeller.edu
September 10, 2025 at 3:34 PM
Shortly before his death last month, James Hudspeth and his team achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience
A new study from the Alushin lab shows how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex. Dysregulated afadin expression has been associated with carcinogenesis and cancer metastasis. #RockefellerScience
Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature
Afadin strengthens adherens junctions by stabilizing cadherin-catenin complex clusters on curved F-actin.
www.science.org
February 27, 2025 at 5:24 PM
A new study from the Alushin lab shows how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex. Dysregulated afadin expression has been associated with carcinogenesis and cancer metastasis. #RockefellerScience
Published in @cp-cancercell.bsky.social, the #RavetchLab demonstrates in a phase 1 clinical trial that an engineered antibody improves a class of cancer drugs—called CD40 agonist antibodies—that has struggled to make good on its early promise. #RockefellerScience
Immunotherapy drug eliminates aggressive cancers in clinical trial - News
The researchers demonstrate that an engineered antibody improves a class of drugs that has struggled to make good on its early promise.
www.rockefeller.edu
August 14, 2025 at 5:41 PM
Published in @cp-cancercell.bsky.social, the #RavetchLab demonstrates in a phase 1 clinical trial that an engineered antibody improves a class of cancer drugs—called CD40 agonist antibodies—that has struggled to make good on its early promise. #RockefellerScience
A newly created atlas of 21 million cells from @junyuecao.bsky.social's lab led by @tommyz626.bsky.social could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies. #RockefellerScience
Study reveals how unexpected shifts in cell populations are revising our understanding of the aging process - News
A newly created atlas of 21 million cells could provide fresh directions for anti-aging therapies.
www.rockefeller.edu
December 11, 2024 at 7:21 PM
A newly created atlas of 21 million cells from @junyuecao.bsky.social's lab led by @tommyz626.bsky.social could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies. #RockefellerScience
A new study from @sohailtavazoie.bsky.social's lab provides the first evidence of genetic predisposition to breast cancer metastasis, with far-reaching clinical implications—including a potential therapy that could prevent it. #RockefellerScience
Researchers discover a genetic disposition increasing the risk of breast cancer metastasis - News
Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original tumor. Thus, for over 50 years now, scientists have been on a quest to identify which malignant mut...
www.rockefeller.edu
December 9, 2024 at 4:03 PM
A new study from @sohailtavazoie.bsky.social's lab provides the first evidence of genetic predisposition to breast cancer metastasis, with far-reaching clinical implications—including a potential therapy that could prevent it. #RockefellerScience
A study from the #RutaLab explained how the fruit fly brain coordinates courtship and aggressive competition—a framework which could help scientists understand how the human brain balances cooperation and competition. #RockefellerScience #YearInReview
🔗: https://bit.ly/4gI7phV
🔗: https://bit.ly/4gI7phV
December 31, 2025 at 11:11 AM
A study from the #RutaLab explained how the fruit fly brain coordinates courtship and aggressive competition—a framework which could help scientists understand how the human brain balances cooperation and competition. #RockefellerScience #YearInReview
🔗: https://bit.ly/4gI7phV
🔗: https://bit.ly/4gI7phV
A study from the Birsoy lab showed that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience #YearInReview
🔗: https://bit.ly/44GfOPG
🔗: https://bit.ly/44GfOPG
December 26, 2025 at 4:36 PM
A study from the Birsoy lab showed that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience #YearInReview
🔗: https://bit.ly/44GfOPG
🔗: https://bit.ly/44GfOPG
Scientists in the #HeintzLab discovered an identical neural circuit that operates differently in male and female mice. #RockefellerScience
This brain circuit drives the urge to mate. Except when it doesn’t. - News
Scientists discovered an identical neural circuit that operates differently in male and female mice.
www.rockefeller.edu
July 11, 2025 at 6:33 PM
Scientists in the #HeintzLab discovered an identical neural circuit that operates differently in male and female mice. #RockefellerScience