#SBGridSoftware
New Title Alert: easymode- a collection of general pretrained networks for cellular cryoET.

Learn more here: buff.ly/mLbcUbZ

#SBGrid #SBGridSoftware
easymode
buff.ly
March 13, 2026 at 4:05 PM
New Title Alert: BindCraft- a user friendly and accurate binder design pipeline.

Learn more here: https://buff.ly/3CEqPpU

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - martinpacesa/BindCraft: User friendly and accurate binder design pipeline
User friendly and accurate binder design pipeline. Contribute to martinpacesa/BindCraft development by creating an account on GitHub.
buff.ly
February 6, 2025 at 12:00 PM
New Title Alert: Boltz-1- an open-source model which predicts the 3D structure of proteins, rna, dna and small molecules; it handles modified residues, covalent ligands & glycans.

Learn more here: https://buff.ly/3ZAPowA

#SBGridSoftware #SBGrid
GitHub - jwohlwend/boltz: Official repository for the Boltz-1 biomolecular interaction model
Official repository for the Boltz-1 biomolecular interaction model - jwohlwend/boltz
buff.ly
December 16, 2024 at 5:00 PM
New Title Alert: AITom- an open-source platform for AI driven cellular electron cryo-tomography analysis.

Learn more here: buff.ly/LLGhjvY

#SBGrid #SBGridSoftware #StructuralBiology
Research
Xu Lab of Computational Biology
buff.ly
August 12, 2025 at 4:03 PM
New Title Alert: ARCTIC-3D- a software for data-mining and clustering of protein interface information.

Learn more here: buff.ly/IbbwP2N

#SBGridSoftware #StructuralBiology #SBGrid
Arctic3D Webserver
Home
buff.ly
October 10, 2025 at 4:07 PM
New Title Alert: Doppio- a new web-based user interface for CCP-EM and RELION software.

Learn more here: https://buff.ly/3WLnBaW

#SBGridSoftware #StructuralBiology
CCP-EM: Collaborative Computational Project for Electron cryo-Microscopy
Collaborative Computational Project for Electron cryo-Microscopy
buff.ly
February 11, 2025 at 12:00 PM
New Title Alert: Icecream- a self-supervised framework for cryo-ET reconstruction that integrates equivariance principles from modern imaging theory into a deep-learning architecture.

Learn more here: buff.ly/bdepEUm

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - swing-research/icecream: 🍦Icecream: a self-supervised framework for cryo-ET reconstruction
🍦Icecream: a self-supervised framework for cryo-ET reconstruction - swing-research/icecream
buff.ly
November 19, 2025 at 5:03 PM
New Title Alert: UGENE- a free open-source bioinformatics software for macOS, and Linux.

Learn more here: ugene.net

#SBGridSoftware #SBGrid #StructuralBiology
Unipro UGENE - Integrated Bioinformatics Tools
UGENE is a free open source software for DNA and protein sequence visualization, alignment, assembly and annotation
ugene.net
August 29, 2025 at 4:04 PM
New Title Alert: CryoSTAR- a neural network based framework for recovering conformational heterogenity of protein complexes.

Learn more here: https://buff.ly/40epdfA

#SBGrid #SBGridSoftware #StructuralBiology
cryoSTAR
Leveraging Structural Prior and Constraints for Cryo-EM Heterogeneous Reconstruction
buff.ly
January 15, 2025 at 5:00 PM
New Title Alert: DeepFRI- a tool for deep functional residue identification.

Learn more here: https://buff.ly/4fVzEdo

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - flatironinstitute/DeepFRI: Deep functional residue identification
Deep functional residue identification. Contribute to flatironinstitute/DeepFRI development by creating an account on GitHub.
buff.ly
December 24, 2024 at 5:00 PM
New Title Alert: Follow_Relion_Gracefully- a complete dashboard for easy interaction with your cryo-EM data in Relion, now with full #teamtomo support!

Learn more here: buff.ly/SvNR5si

#SBGridsoftware #StructuralBiology
GitHub - dzyla/Follow_Relion_gracefully: New program to follow Relion projects in a browser!
New program to follow Relion projects in a browser! - dzyla/Follow_Relion_gracefully
buff.ly
June 17, 2025 at 5:06 PM
New Title Alert: DenoisET- an implementation of the Noise2Noise algorithm specifically designed for cryoET data denoising.

Learn more here: buff.ly/8i8i87U

#SBGrid #SBGridSoftware #StructualBiology
GitHub - apeck12/denoiset: An implementation of Noise2Noise for cryoET data
An implementation of Noise2Noise for cryoET data. Contribute to apeck12/denoiset development by creating an account on GitHub.
buff.ly
August 14, 2025 at 4:14 PM
New Title Alert: HADDOCK3- is the next generation integrative modeling software in the long-lasting HADDOCK project.

Learn more here: buff.ly/gInH6VV

#SBGrid #SBGridSoftware #StructuralBiology
A brief introduction to HADDOCK3 — haddock3 3.0.0 documentation
HADDOCK3 is the next generation integrative modelling software in the long-lasting HADDOCK project. It represents a complete rethinking and rewriting of the HADDOCK2.X series, implementing a new way…
buff.ly
October 24, 2025 at 4:08 PM
New Title Alert: AlphaFlow- a modified version of AlphaFold, fine-tuned with a flow matching objective, designed for generative modeling of protein conformational ensembles.

Learn more here: https://buff.ly/4gwVW5o

#SBGrid #SBGridsoftware #StructuralBiology
GitHub - bjing2016/alphaflow: AlphaFold Meets Flow Matching for Generating Protein Ensembles
AlphaFold Meets Flow Matching for Generating Protein Ensembles - bjing2016/alphaflow
buff.ly
January 27, 2025 at 5:00 PM
New Title Alert: Slabify- is a command-line tool designed for the automatic segmentation of lamella slabs in cryo-electron tomography (cryo-ET) volumes.

Learn more here: buff.ly/fVsKsOS

#SBGrid #SBGridSoftware
GitHub - CellArchLab/slabify-et: A CLI tool to segment the lamella slab in cryo-ET volumes
A CLI tool to segment the lamella slab in cryo-ET volumes - CellArchLab/slabify-et
buff.ly
February 25, 2026 at 5:07 PM
New Title Alert: Ais- a tool that provides annotation and segmentation of cryo-ET data using convolutional neural networks.

Learn more here: buff.ly/29QIm9Q

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - bionanopatterning/Ais
Contribute to bionanopatterning/Ais development by creating an account on GitHub.
buff.ly
November 5, 2025 at 5:01 PM
New Title Alert: ChemEM- a tool that utilizes information from Cryo-EM density and state-of-the-art small molecule force fields to dock small molecules into protein targets.

Learn more here: https://buff.ly/3NUvcPM

#SBGrid #SBGridsoftware #structuralbiology
ChemEM
ChemEM utilizes information from Cryo-EM density and state-of-the-art small molecule force fields to dock small molecules into protein targets.
buff.ly
November 20, 2024 at 5:06 PM
New Title Alert: RoseTTAFold2- a tool that extends the original three-track architecture of RoseTTAFold over the full network.

Learn more here: buff.ly/wQ22ZM2

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - uw-ipd/RoseTTAFold2
Contribute to uw-ipd/RoseTTAFold2 development by creating an account on GitHub.
buff.ly
November 7, 2025 at 5:31 PM
New Title Alert: CCPEM-pipeliner- an integrated suite of software tools for processing single particle cryoEM data, from preprocessing raw image data through building and fitting atomic models.

Learn more here: buff.ly/eXK1ka2

#SBGrid #SBGridsoftware #StructuralBiology
ccpem / ccpem-pipeliner · GitLab
Python pipeliner for CCP-EM and RELION
buff.ly
July 9, 2025 at 4:05 PM
New Title Alert: ConSurf- is a bioinformatics tool designed for estimating the evolutionary conservation of amino and nucleic acid positions in protein, DNA, and RNA molecules.

Learn more here: buff.ly/ormnLqE

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - Rostlab/ConSurf: Evolutionary conservation estimation of residues or nucleotides
Evolutionary conservation estimation of residues or nucleotides - Rostlab/ConSurf
buff.ly
February 10, 2026 at 5:04 PM
New Title Alert: Tomcat- a web-based tool designed for cataloging and managing tomography data providing an easy way to view, annotate, and organize tomograms.

Learn more here: buff.ly/75XbvPv

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - shahpnmlab/tomcat: Tomography Catalogue Tool
Tomography Catalogue Tool. Contribute to shahpnmlab/tomcat development by creating an account on GitHub.
buff.ly
July 21, 2025 at 4:11 PM
New Title Alert: BindCraft- a user friendly and accurate binder design pipeline.

Learn more here: buff.ly/GJJ6wUR

#SBGrid #SBGridSoftware #StructuralBiology
October 15, 2025 at 5:15 PM
New Title Alert: Ais- a tool that provides annotation and segmentation of cryo-ET data using convolutional neural networks.

Learn more here: https://buff.ly/4gjsSOu

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - bionanopatterning/Ais
Contribute to bionanopatterning/Ais development by creating an account on GitHub.
buff.ly
December 13, 2024 at 5:00 PM
New Title Alert: CryoTransformer- a powerful and accurate particle-picking framework using Residual Network (ResNet) and Transformer.

Learn more here: buff.ly/28aft69

#SBGrid #SBGridSoftware #StructuralBiology
July 15, 2025 at 4:05 PM
New Title Alert: FoldBench- a comprehensive all-atom benchmark for biomolecular structure prediction that spans proteins, nucleic acids, ligands, and six major interaction types.

Learn more here: buff.ly/NE4INJW

#SBGrid #SBGridSoftware #StructuralBiology
GitHub - BEAM-Labs/FoldBench
Contribute to BEAM-Labs/FoldBench development by creating an account on GitHub.
buff.ly
August 29, 2025 at 8:35 PM