Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening #SLASDiscov www.slas-discovery.org/article/S247...
Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening
False-positives plague High Throughput Screening in general and are costly as they
consume resource and time to resolve. Methods that can rapidly identify such compounds
at the initial screen are ther...
www.slas-discovery.org
July 22, 2025 at 4:26 AM
Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening #SLASDiscov www.slas-discovery.org/article/S247...
#FGF9 #Senescence #Senomorphic
Secretome (1204 proteins) screening on Senescent features (p21 Cell area Nuclei area) of primary👤lung fibroblast -/+Etoposide
Inducer▶️IFNα5/14/16/17
Inhibitors▶️FGF4/9/20
FGF9⏬SASP in normal/IPF lung fibroblast
#SLASDiscov 2025
www.slas-discovery.org/article/S247...
Secretome (1204 proteins) screening on Senescent features (p21 Cell area Nuclei area) of primary👤lung fibroblast -/+Etoposide
Inducer▶️IFNα5/14/16/17
Inhibitors▶️FGF4/9/20
FGF9⏬SASP in normal/IPF lung fibroblast
#SLASDiscov 2025
www.slas-discovery.org/article/S247...
March 7, 2025 at 7:59 PM
#FGF9 #Senescence #Senomorphic
Secretome (1204 proteins) screening on Senescent features (p21 Cell area Nuclei area) of primary👤lung fibroblast -/+Etoposide
Inducer▶️IFNα5/14/16/17
Inhibitors▶️FGF4/9/20
FGF9⏬SASP in normal/IPF lung fibroblast
#SLASDiscov 2025
www.slas-discovery.org/article/S247...
Secretome (1204 proteins) screening on Senescent features (p21 Cell area Nuclei area) of primary👤lung fibroblast -/+Etoposide
Inducer▶️IFNα5/14/16/17
Inhibitors▶️FGF4/9/20
FGF9⏬SASP in normal/IPF lung fibroblast
#SLASDiscov 2025
www.slas-discovery.org/article/S247...