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#ScienceReadForSunday: Efficacy and safety of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated plasmodium falciparum malaria in South Sudan: a multi-site therapeutic efficacy study, 2024–2025

link.springer.com/article/10.1...
Efficacy and safety of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated plasmodium falciparum malaria in South Sudan: a multi-site therapeutic efficacy study, 2024–2025 - Malaria Journal
Background South Sudan has one of the highest malaria burdens per capita in Africa, and artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) are first- and second-line treatments for…
link.springer.com
October 4, 2026 at 9:15 AM
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#ScienceReadForSunday: Use of procalcitonin point-of-care testing to guide de-escalation of antibiotic therapy in adults with suspected bacterial sepsis in a tertiary hospital in Bangladesh: a randomised controlled open-label trial
www.thelancet.com/journals/ecl...
Use of procalcitonin point-of-care testing to guide de-escalation of antibiotic therapy in adults with suspected bacterial sepsis in a tertiary hospital in Bangladesh: a randomised controlled open-label trial
In this single-centre trial in Bangladesh, procalcitonin-guided de-escalation reduced the duration of antibiotic therapy in adults with suspected bacterial sepsis. Mortality and recurrent infection…
www.thelancet.com
October 4, 2026 at 9:15 AM
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#ScienceReadForSunday: A data leak shut a top research biobank: lessons from the recovery
www.nature.com/articles/d41...
A data leak shut a top research biobank: lessons from the recovery
UK Biobank is imposing new safety measures after a security incident, but safeguarding biomedical data while enabling researcher access remains a challenge.
www.nature.com
September 27, 2026 at 9:15 AM
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#ScienceReadForSunday: A data leak shut a top research biobank: lessons from the recovery www.nature.com/articles/d41...
A data leak shut a top research biobank: lessons from the recovery
UK Biobank is imposing new safety measures after a security incident, but safeguarding biomedical data while enabling researcher access remains a challenge.
www.nature.com
September 27, 2026 at 9:15 AM
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#ScienceReadForSunday: Advancing equity through community-led, globally connected infectious disease research
www.nature.com/articles/s41...
Advancing equity through community-led, globally connected infectious disease research - Nature Microbiology
Platforms for community-led but globally connected knowledge and resource sharing can move us towards more equitable and more effective research and solutions for infectious diseases.
www.nature.com
September 20, 2026 at 9:15 AM
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#ScienceReadForSunday: Probabilistic classification of late treatment failure in uncomplicated malaria
www.medrxiv.org/content/10.1...
Probabilistic classification of late treatment failure in uncomplicated malaria
Distinguishing treatment failure (recrudescence) from reinfection in uncomplicated falciparum malaria is essential for characterising antimalarial treatment efficacy in malaria endemic areas.…
www.medrxiv.org
September 20, 2026 at 9:15 AM
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#ScienceReadForSunday: A small-molecule myosin inhibitor as a targeted multi-stage antimalarial www.biorxiv.org/content/10.1...
https://www.biorxiv.org/content/10.1101/2022.09.09.507317v1
www.biorxiv.org
September 13, 2026 at 9:15 PM
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#ScienceReadForSunday: Use of procalcitonin point-of-care testing to guide de-escalation of antibiotic therapy in adults with suspected bacterial sepsis in a tertiary hospital in Bangladesh: a randomised controlled open-label trial
www.thelancet.com/journals/ecl...
Use of procalcitonin point-of-care testing to guide de-escalation of antibiotic therapy in adults with suspected bacterial sepsis in a tertiary hospital in Bangladesh: a randomised controlled open-label trial
In this single-centre trial in Bangladesh, procalcitonin-guided de-escalation reduced the duration of antibiotic therapy in adults with suspected bacterial sepsis. Mortality and recurrent infection…
www.thelancet.com
September 13, 2026 at 9:15 AM
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#ScienceReadForSunday: Estimating the changing prevalence of molecular markers of artemisinin partial resistance in #Plasmodium #falciparum #malaria in Sub-Saharan Africa
www.medrxiv.org/content/10.6...
Estimating the changing prevalence of molecular markers of artemisinin partial resistance in Plasmodium falciparum malaria in Sub-Saharan Africa
Background Artemisinin-based combination therapies (ACTs) are the most widely used treatment for Plasmodium falciparum malaria. Kelch 13 mutations associated with artemisinin partial resistance…
www.medrxiv.org
September 6, 2026 at 9:15 AM
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#ScienceReadForSunday: Data retrieval and harmonisation for #IPD meta-analysis in the context of a #NTD - challenges and lessons from the #IDDO #VisceralLeishmaniasis data platform
bmjpublichealth.bmj.com/content/4/3/...
https://bmjpublichealth.bmj.com/content/4/3/e003986
bmjpublichealth.bmj.com
September 6, 2026 at 9:15 AM
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#ScienceReadForSunday: The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage #Plasmodium #falciparum in healthy adults with experimental #malaria
www.science.org/doi/10.1126/...
The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage Plasmodium falciparum in healthy adults with experimental malaria
The fast-acting antimalarial drug MMV367 rapidly killed blood-stage parasites in healthy volunteers experimentally infected with Plasmodium falciparum.
www.science.org
August 16, 2026 at 9:15 AM
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#ScienceReadForSunday: A Smart Investment: The Health, Education and Economic Returns of #Malaria #Chemoprevention in School-Aged Children across Ten High-Burden Countries doi.org/10.1017/bca....
A Smart Investment: The Health, Education and Economic Returns of Malaria Chemoprevention in School-Aged Children across Ten High-Burden Countries | Journal of Benefit-Cost Analysis | Cambridge Core
A Smart Investment: The Health, Education and Economic Returns of Malaria Chemoprevention in School-Aged Children across Ten High-Burden Countries
doi.org
August 9, 2026 at 9:15 AM
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#ScienceReadForSunday: Consensus framework for developing a target product profile of real-time PCR in Chagas disease therapeutic monitoring
journals.plos.org/plosntds/art...
Consensus framework for developing a target product profile of real-time PCR in Chagas disease therapeutic monitoring
Chagas disease remains a neglected global health problem with major diagnostic and therapeutic challenges. Progression from acute to chronic infection may lead to cardiac or digestive complications…
journals.plos.org
August 9, 2026 at 9:15 AM
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#ScienceReadForSunday: The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa doi.org/10.1126/scie...
The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa
The invasive urban malaria vector Anopheles stephensi threatens 126 million city dwellers in Africa. Controlling An. stephensi requires greater understanding of its origin, invasion dynamics, and…
doi.org
August 2, 2026 at 9:15 AM
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#ScienceReadForSunday: Assessing Health-Related Quality of life and socioeconomic impacts in low-endemic schistosomiasis: A study from Rural China
journals.plos.org/plosntds/art...
Assessing Health-Related Quality of life and socioeconomic impacts in low-endemic schistosomiasis: A study from Rural China
Author summary In areas where schistosomiasis is nearly eliminated (“low-endemic”), the long-term health and socioeconomic impacts on patients with chronic complications like Advanced Schistosomiasis…
journals.plos.org
August 2, 2026 at 9:15 AM
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#ScienceReadForSunday: Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis
link.springer.com/article/10.1...
Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis - Malaria Journal
Background The 8-aminoquinoline antimalarials are used to prevent P. vivax relapses. Recent evidence suggests high total dose primaquine (7 mg/kg) provides optimal efficacy, however, many countries,…
link.springer.com
July 26, 2026 at 9:15 AM
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#ScienceReadForSunday: Assessing the sustainability of Rwanda’s mass drug administration program for #schistosomiasis and #STHs: A mixed-methods application of the program sustainability assessment tool
journals.plos.org/plosntds/art...
Assessing the sustainability of Rwanda’s mass drug administration program for schistosomiasis and soil-transmitted helminthiasis: A mixed-methods application of the program sustainability assessment tool
Author summary This study evaluated the sustainability of Rwanda’s mass drug administration (MDA) program for schistosomiasis and soil-transmitted helminthiasis. Using interviews and a standardized…
journals.plos.org
July 26, 2026 at 9:15 AM
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#ScienceReadForSunday: Structural basis for host membrane binding and remodeling by invading malaria parasites
dx.doi.org/10.1016/j.ce...
Redirecting
dx.doi.org
July 19, 2026 at 9:15 AM
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#ScienceReadForSunday: Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with #Plasmodium #vivax #malaria in Ethiopia: a systematic review and individual patient data meta-analysis
link.springer.com/article/10.1...
Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis - Malaria Journal
Background The 8-aminoquinoline antimalarials are used to prevent P. vivax relapses. Recent evidence suggests high total dose primaquine (7 mg/kg) provides optimal efficacy, however, many countries,…
link.springer.com
July 19, 2026 at 9:15 AM
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#ScienceReadForSunday: Accelerating vaccine research and development for skin neglected tropical diseases: A case for leishmaniasis, leprosy, and Buruli ulcer

journals.plos.org/plosntds/art...
Accelerating vaccine research and development for skin neglected tropical diseases: A case for leishmaniasis, leprosy, and Buruli ulcer
Neglected tropical diseases (NTDs), particularly those with prominent cutaneous manifestations such as leishmaniasis, leprosy, and Buruli ulcer, represent a substantial global health burden,…
journals.plos.org
July 12, 2026 at 9:15 AM
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#ScienceReadForSunday: Beyond bread and beer, alluring yeast species could yield new mosquito traps to combat #malaria
phys.org/news/2026-06...
Beyond bread and beer, alluring yeast species could yield new mosquito traps to combat malaria
An orange-colored yeast species isolated from a Baltimore sidewalk several years ago could be the basis of eco-friendly mosquito traps that reduce malaria transmission, according to a new study from…
phys.org
July 12, 2026 at 9:15 AM
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#ScienceReadForSunday: Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis
link.springer.com/article/10.1...
Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis - Malaria Journal
Background The 8-aminoquinoline antimalarials are used to prevent P. vivax relapses. Recent evidence suggests high total dose primaquine (7 mg/kg) provides optimal efficacy, however, many countries,…
link.springer.com
July 5, 2026 at 9:15 AM
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#ScienceReadForSunday: Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis
link.springer.com/article/10.1...
Analysis of the effect of primaquine dose on efficacy, safety, and tolerability in patients with Plasmodium vivax malaria in Ethiopia: a systematic review and individual patient data meta-analysis - Malaria Journal
Background The 8-aminoquinoline antimalarials are used to prevent P. vivax relapses. Recent evidence suggests high total dose primaquine (7 mg/kg) provides optimal efficacy, however, many countries,…
link.springer.com
July 5, 2026 at 9:15 AM
iddonews.bsky.social
#ScienceReadForSunday: From invisibility to political power: Policy lessons from a decade of Brazil’s Social Forum for Infectious and Neglected Diseases journals.plos.org/plosntds/art...
From invisibility to political power: Policy lessons from a decade of Brazil’s Social Forum for Infectious and Neglected Diseases
Author summary Neglected tropical diseases (NTDs) mainly affect people living in poverty, who are often discriminated against and far from decision-making spaces. Technical solutions (drugs,…
journals.plos.org
June 28, 2026 at 9:15 AM
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#ScienceReadForSunday: A snapshot of selected neglected tropical disease research using the World Health Organization International Clinical Trials Registry Platform database, 1999–2023
journals.plos.org/plosntds/art...
A snapshot of selected neglected tropical disease research using the World Health Organization International Clinical Trials Registry Platform database, 1999–2023
Author summary Neglected tropical diseases (NTDs) are a group of conditions which have devastating impacts on communities, particularly those in low- and middle-income countries where access to…
journals.plos.org
June 21, 2026 at 9:15 AM