New paper 🧠 HBK-10 engages sigma-1 receptors, protects neuronal cells from amyloid-beta injury, and improves selected memory domains under NMDA receptor hypofunction in mice.
Read: doi.org/10.1016/j.bc...
#Neuropharmacology #Sigma1Receptor #nCureLab

From cellular signaling to clinical trials: This review examines the therapeutic potential of sigma-1 receptor modulation in neurodegenerative diseases🧠
www.mdpi.com/2227-9059/13...
#Sigma1Receptor #Neurodegeneration #ALS #Alzheimers

🔬 The 6th Sigma Symposium in Kraków — by the numbers.

123 in-person participants · 24 countries · strong ITC and early-career participation.

Thank you to all who took part! 🙏

#SIGMA1EUROPE #Sigma1Receptor #COSTAction

Register now!

6th Sigma Symposium / 2nd SIGMA-1EUROPE Meeting

June 9-11, 2026 | Krakow

Hosted by Jagiellonian University & Jagiellonian University Medical College

Deadline: 31 March 2026

Details & registration:

sigma1europe.eu/event/6th-si...

#Sigma1Europe #COSTAction #Sigma1Receptor

📢 Join the 1st SIGMA-1 EUROPE Training School

📍 Pavia, Italy
📅 Mar 30–Apr 2, 2026
⏰ Deadline: Jan 31, 2026

👉 Apply now: sigma1europe.eu/application-...

#SIGMA1Europe #COSTAction #Sigma1Receptor #PhD #Postdoc #EarlyCareerResearchers

Our new paper in Neurotherapeutics shows that the multimodal compound HBK-15 reverses memory deficits under NMDA receptor hypofunction via sigma-1 receptor activation.

Read more: www.linkedin.com/posts/labora...

#neuropharmacology #sigma1receptor #HBK15 #ncurelab

Sigma-1 receptor activation by PRE-084 attenuates sepsis-associated encephalopathy by targeting microglial p38 MAPK-mediated neuroinflammation and neuronal endoplasmic reticulum stress.
Kang, Wen, Pan, Xia et al.
Paper
Details
#Sigma1Receptor #Neuroinflammation #SepsisResearch

📢 Just 2 weeks to go!

The 5th European Symposium & 1st SIGMA-1EUROPE Meeting on the Physiopathology of Sigma-1 Receptors is happening soon!

📍 Granada, Spain

📅 June 25–27, 2025

Don’t miss it!

#Sigma1Europe #Sigma1Receptor #COSTAction #Granada2025

Travel for science! ✈️ SIGMA-1EUROPE STSM grants (up to €4,000) fund research visits on Sigma-1 Receptor projects. 5 days to 3 months, open to all. Apply by 15 Sep 2025:

shorturl.at/jFtbB
cost.eu/actions/CA23156

#ScienceTravel #Research #Sigma1Receptor

Researchers from ITC countries: SIGMA-1EUROPE offers ITC Conference Grants (up to €2,000) to share your Sigma-1 Receptor work at conferences. 🎤 Apply by 15 Sep 2025! ✅ Check it out:
shorturl.at/OHEBk
cost.eu/actions/CA23156

#Science #ResearchFunding #Sigma1Receptor