#SmallSignsBigScience
Small Signs, Big Science | Part 3
Beautiful on Day 3... then few or no blastocysts.

Morphology is just a snapshot. Genome activation, metabolism, compaction, and polarity are still unfolding.

Small sign: compaction. Big science: competence.

#SmallSignsBigScience #Embryology
August 10, 2026 at 9:41 PM
Small Signs, Big Science | Part 2

The quiet second before -196°C.

After loading on the vitrification carrier, the next seconds still matter: minimal droplet, cryoprotectant exposure, prompt movement into liquid nitrogen.

Small sign. Big cryobiology.

#SmallSignsBigScience #IVF #Embryology
May 22, 2026 at 1:03 AM
Starting a new series: Small Signs, Big Science.

Part 1: When 2PN Isn’t the Full Story.

A zygote may look 2PN. Then time-lapse reveals a tiny microPN later.

A reminder that embryology is not only about what we see, but when we see it.

#Embryology #IVF #FertilityScience #SmallSignsBigScience
May 15, 2026 at 8:34 PM