#Sofosbuvir
Para sífilis? Benzetacil.
Para gonorreia? Ceftriaxona.
Para clamídia? Doxiciclina.
Para hepatite B? Tenofovir.
Para hepatite C? Daclatasvir + sofosbuvir.
Para cancro mole? Azitromicina.
Para HPV? Cauterização/cirurgia.

Para todas?
Cuidado centrado em cada indivíduo. ❤️‍🩹
April 23, 2026 at 3:19 PM
Para sífilis? Benzetacil.
Para gonorreia? Ceftriaxona.
Para clamídia? Doxiciclina.
Para hepatite B? Tenofovir.
Para hepatite C? Daclatasvir + sofosbuvir.
Para cancro mole? Azitromicina.
Para HPV? Cauterização/cirurgia.

Para todas?
Rastreio, conscientização e prevenção focada em cada indivíduo. ❤️‍🩹
September 22, 2024 at 2:23 PM
About a decade ago, we found a reliable cure for Hep C, sofosbuvir, which has made around $100B for drug companies.

You take it for 12 weeks. Your Hep C is cured. The end.
April 19, 2026 at 12:11 AM
Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People With Hepatitis C Virus

#IDSky
Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People With Hepatitis C Virus
Treatment of hepatitis C virus (HCV) during pregnancy can cure maternal HCV and prevent perinatal HCV transmission. The primary objective was to compare the pharmacokinetics (PK) of sofosbuvir (SOF)/velpatasvir (VEL) in pregnant versus nonpregnant people.
academic.oup.com
May 11, 2025 at 6:58 PM
Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People with Hepatitis C Virus

✅ Just Accepted
#IDSky
Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People with Hepatitis C Virus
Treatment of hepatitis C virus (HCV) during pregnancy can cure maternal HCV and prevent perinatal HCV transmission. The primary objective was to compare the pharmacokinetics (PK) of sofosbuvir/velpatasvir (SOF/VEL) in pregnant versus nonpregnant people.
buff.ly
December 21, 2024 at 1:41 PM
Then, while I onboard those interventions, acquire truvada and sofosbuvir so we can discuss and try an antiviral combo after our next visit. The sofosbuvir will be coming from India so it’ll take a while to get to me.
December 20, 2024 at 10:51 PM
Everything is shit but the Sofosbuvir I ordered from abroad is almost here so once I get back to baseline post-rapamycin my doc and I can start my antiviral combo!!! I know truvada and Sofosbuvir don’t work for everyone, but they’ve worked for some and I just really need a #LongCOVID win these days.
January 28, 2025 at 10:31 PM
In CID, Catherine Chappell, MD MSc, and colleagues compare the pharmacokinetics (PK) of sofosbuvir/velpatasvir (SOF/VEL) in pregnant versus nonpregnant people.
Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People with Hepatitis C Virus
Treatment of hepatitis C virus (HCV) during pregnancy can cure maternal HCV and prevent perinatal HCV transmission. The primary objective was to compare the pharmacokinetics (PK) of sofosbuvir/velpatasvir (SOF/VEL) in pregnant versus nonpregnant people.
academic.oup.com
December 26, 2024 at 7:33 PM
Using AI to try to identify/repurpose antiviral compounds that may work well against HPAI: sofosbuvir and GS441524 good candidates, but need to be validated.
👉 www.mdpi.com/1999-4915/17...
July 17, 2025 at 1:22 AM
Since I can’t take any of the US antivirals OR ensitrelvir to try to treat my #LongCOVID, I’m now looking at Sofosbuvir (Hep C antiviral that may be effective against SC2). Anyone take it? What have your experiences been?
December 15, 2024 at 11:11 PM
My second installment of "Classics in Medicinal Chemistry" describes the design and development of a truly revolutionary drug for treating Hepatitis C. It's a masterclass in medicinal chemistry and biochemistry detective work. medchemash.substack.com/p/classics-i...
Classics in Medicinal Chemistry #2: Sofosbuvir
Sovaldi
medchemash.substack.com
January 21, 2025 at 9:44 PM
At Johns Hopkins, Iowa State, and University of Minnesota, scientists found that SARS-CoV-2 evades key antivirals like bemnifosbuvir and sofosbuvir by shifting viral RNA from the polymerase to a proofreading enzyme that cuts the drugs out.

www.nature.com/articles/s41...
Client Challenge
www.nature.com
January 14, 2026 at 9:54 PM
I’m on day 5 of Sofosbuvir. The first two days I only took one pill, but have been taking 2 the other two days. Very up and down but the ups are very up. My nervous system feels very calm on those days.
February 11, 2025 at 11:59 PM
Interrupted research in life sciences is dead patients. My Dad died of hepatitis C in 2013, just as the interferon free drugs arrived. NIH investments saved many lives via those drugs, just not fast enough. pmc.ncbi.nlm.nih.gov/articles/PMC...
Public funding for transformative drugs: the case of sofosbuvir
Transformative drugs often emerge from investment by public and private actors. Sofosbuvir changed hepatitis C care, but had public support through NIH. An estimated $60.9 million in public dollars su...
pmc.ncbi.nlm.nih.gov
July 24, 2026 at 1:17 PM
New at @lancetchildadol.bsky.social - Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study

www.thelancet.com/journals/lan...

#LiverSky #HepSky
Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study
No change in growth or sexual development was detected during prolonged follow-up of paediatric patients who had completed treatment with sofosbuvir-based direct-acting antivirals for chronic HCV. Pro...
www.thelancet.com
April 1, 2025 at 1:59 PM
Sofosbuvir-daclatasvir proved equally effective as sofosbuvir-velpatasvir, offering promising treatment strategies for hepatitis C.

by Cooke GS, Hung LM (...) Walker AS et 28 al. in Lancet #MedSky

👉 get more here

📖 read the article:
Treatment options to support the elimination of hepatitis C: an open-label, factorial, randomised controlled non-inferiority trial
WHO recommends treating hepatitis C infection with one of three antiviral combinations for 8–12 weeks. No randomised trials have compared these regime…
www.sciencedirect.com
May 26, 2025 at 2:34 PM
#OTILT is that combining sofosbuvir with amiodarone can cause bradycardia, and this interaction should be avoided.

@bwdionne.bsky.social
@jeffpears0n.bsky.social
@saanyav.bsky.social

pmc.ncbi.nlm.nih.gov/articles/PMC...
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pmc.ncbi.nlm.nih.gov
May 20, 2026 at 7:22 PM
New data presented by Datuk Dr Radzi Abu Hassan at the 2025 #EASLCongress showed that the ravidasvir/sofosbuvir treatment can be safely shortened from 12 to 8 weeks. This shorter regimen is intended for people living with #HepC who do not have cirrhosis.
Link to the poster: dndi.org/wp-content/u...
June 30, 2025 at 11:20 AM
Unfortunately - this doesn't Fact Check because they are ALL available generic. At Walmart and likely LESS at CostPlus but....

Albuterol - $34
Atorvastatin - $9
Azithromycin - $8
Sofosbuvir - $9k (that is ridiculous)

Stop inflating by quoting the brand price when generics are readily available.
September 12, 2025 at 8:57 PM
"É inaceitável que, após uma luta tão longa para garantir a produção de genéricos e romper o monopólio da Gilead, o Brasil continue pagando caro pelo sofosbuvir. Permanecer pagando preços inflacionados é uma afronta ao direito à saúde e à boa gestão dos recursos públicos."
COMO PATENTES ATRASAM O COMBATE ÀS HEPATITES
Para prolongar lucros com sofosbuvir, remédio que cura a hepatite C, empresa dos EUA chegou a bloquear genérico no Brasil – encarecendo e dificultando ações contra a doença. Reforçar soberania em tecnologias de saúde se mostra essencial
Como patentes atrasam o combate às hepatites | Outras Palavras
Para prolongar lucros com sofosbuvir, remédio que cura a hepatite C, empresa dos EUA chegou a bloquear genérico no Brasil – encarecendo e dificultando ações contra a doença. Reforçar soberania em tecn...
outraspalavras.net
July 25, 2025 at 3:27 PM
Ça m'a littéralement sauvé la vie. (Associé avec une autre molécule) . Ce qu'elle dit me terrifie. Vous avez pas idée !!
September 28, 2026 at 6:44 PM
Sofosbuvir – Wikipedia
de.m.wikipedia.org
March 12, 2025 at 10:52 PM