November 11, 2026 at 4:26 PM
Sorry for spoiling @bignosebug.bsky.social new model 😔
November 12, 2026 at 6:52 PM
Sorry for spoiling @bignosebug.bsky.social new model 😔
Nature research paper: UNC13A splice correction rescues synaptic dysfunction induced by TDP-43 loss
go.nature.com/48aEEbV
go.nature.com/48aEEbV
UNC13A splice correction rescues synaptic dysfunction induced by TDP-43 loss - Nature
TDP-43 loss induces a predegenerative state in which neurons remain structurally intact and suffer a substantial breakdown in synaptic communication; a therapeutic strategy is found that corrects UNC13A cryptic splicing by using splice-switching antisense oligonucleotides.
go.nature.com
November 13, 2026 at 9:01 AM
Nature research paper: UNC13A splice correction rescues synaptic dysfunction induced by TDP-43 loss
go.nature.com/48aEEbV
go.nature.com/48aEEbV
Working my way through VisionQuest now that its all out and clocked that a few episodes are directed by Vincenzo Natali of Cube and Splice fame.
Dope as hell! 👍
Dope as hell! 👍
November 11, 2026 at 7:35 AM
Working my way through VisionQuest now that its all out and clocked that a few episodes are directed by Vincenzo Natali of Cube and Splice fame.
Dope as hell! 👍
Dope as hell! 👍
I am reading a book about joining pieces of rope.
The splice levels are very high!
The splice levels are very high!
November 10, 2026 at 1:56 PM
I am reading a book about joining pieces of rope.
The splice levels are very high!
The splice levels are very high!
Not that I needed yet another reason to dislike him, but the first sentence in the "About Morgan Wallen" section of his new tour press release that went out this morning contains the most *egregious* comma splice.
November 12, 2026 at 3:30 PM
Not that I needed yet another reason to dislike him, but the first sentence in the "About Morgan Wallen" section of his new tour press release that went out this morning contains the most *egregious* comma splice.
the downfall was clear when spitfire audio got bought out by splice then LABS turned fucking GREEN
November 11, 2026 at 6:29 PM
the downfall was clear when spitfire audio got bought out by splice then LABS turned fucking GREEN
The Brothers Hellion: Doc Splice
She just wants to make you happy, don't you wanna be happy?
#oc #comic #thebrothershellion
She just wants to make you happy, don't you wanna be happy?
#oc #comic #thebrothershellion
November 10, 2026 at 6:47 PM
The Brothers Hellion: Doc Splice
She just wants to make you happy, don't you wanna be happy?
#oc #comic #thebrothershellion
She just wants to make you happy, don't you wanna be happy?
#oc #comic #thebrothershellion
splice is a story of icarus. first, they have a sound effects subscription. every sound you download is locally on your computer, you own them. awesome! then they make a plugin that works like eastwest, but it's cheaper cuz its bundled with a tier of splice. Awesome! I don't need your DAW.
November 10, 2026 at 11:18 PM
splice is a story of icarus. first, they have a sound effects subscription. every sound you download is locally on your computer, you own them. awesome! then they make a plugin that works like eastwest, but it's cheaper cuz its bundled with a tier of splice. Awesome! I don't need your DAW.
What a revolutionary thinking!
I often think of genes like TCF7 that can make splice variants with opposite functions.
This is super work!
I often think of genes like TCF7 that can make splice variants with opposite functions.
This is super work!
We use a gene-level measure of isoform evenness that accounts for expression level and isoform number, and apply it to 4,814 GTEx (gtexportal.org/home/) samples from 25 human tissues to quantify isoform diversity (I-DIV) of every gene (e.g. BRCA1) in every tissue.
November 11, 2026 at 7:19 PM
What a revolutionary thinking!
I often think of genes like TCF7 that can make splice variants with opposite functions.
This is super work!
I often think of genes like TCF7 that can make splice variants with opposite functions.
This is super work!
The surprise word spanning search splice fun.
November 11, 2026 at 7:11 AM
The surprise word spanning search splice fun.
Dren from Splice
Splice Creature Encounter
ALT: Splice Creature Encounter
static.klipy.com
November 12, 2026 at 2:04 PM
Dren from Splice
alright, lil electrical job alllll wrapped up!
Monday was very silly, but today was niiiice and easy because I got the bullshit taken care of on Monday.
Just slap in a junction box, splice a few things, test, and clean up and we're groovy
Monday was very silly, but today was niiiice and easy because I got the bullshit taken care of on Monday.
Just slap in a junction box, splice a few things, test, and clean up and we're groovy
November 11, 2026 at 8:39 PM
alright, lil electrical job alllll wrapped up!
Monday was very silly, but today was niiiice and easy because I got the bullshit taken care of on Monday.
Just slap in a junction box, splice a few things, test, and clean up and we're groovy
Monday was very silly, but today was niiiice and easy because I got the bullshit taken care of on Monday.
Just slap in a junction box, splice a few things, test, and clean up and we're groovy
Half assed splice but the context fits perfectly.
Source(s):
old.reddit.com/r/PublicFrea...
imgur.com/a/j0p41YZ
Source(s):
old.reddit.com/r/PublicFrea...
imgur.com/a/j0p41YZ
November 10, 2026 at 10:26 AM
Half assed splice but the context fits perfectly.
Source(s):
old.reddit.com/r/PublicFrea...
imgur.com/a/j0p41YZ
Source(s):
old.reddit.com/r/PublicFrea...
imgur.com/a/j0p41YZ
why the fuck does splice need an ai assistant
November 11, 2026 at 9:52 AM
why the fuck does splice need an ai assistant
Que vuelva splice onto arcane, que vuelva meld que vuelva transmute que vuelva cipher
November 13, 2026 at 3:16 PM
Que vuelva splice onto arcane, que vuelva meld que vuelva transmute que vuelva cipher
1. A comma splice walks into a bar, it has a drink and then leaves.
2. A dangling modifier walks into a bar. After finishing a drink, the bartender asks it to leave.
3. A question mark walks into a bar?
buff.ly/BuVY50d
2. A dangling modifier walks into a bar. After finishing a drink, the bartender asks it to leave.
3. A question mark walks into a bar?
buff.ly/BuVY50d
Seven Bar Jokes Involving Grammar and Punctuation
“A dangling modifier walks into a bar. After finishing a drink, the bartender asks it to leave.” October 1, 2021 6/6/24 8/14/25 11/12/26
buff.ly
November 13, 2026 at 2:20 AM
1. A comma splice walks into a bar, it has a drink and then leaves.
2. A dangling modifier walks into a bar. After finishing a drink, the bartender asks it to leave.
3. A question mark walks into a bar?
buff.ly/BuVY50d
2. A dangling modifier walks into a bar. After finishing a drink, the bartender asks it to leave.
3. A question mark walks into a bar?
buff.ly/BuVY50d
Troll & Dark Elf - Londinium: splice frayed signal rope back into one continuous length. nervous precision and mutual trust.
Explore apps: https://alteredlineage.com/
#gamedev #indiegame #conceptart
Explore apps: https://alteredlineage.com/
#gamedev #indiegame #conceptart
November 10, 2026 at 11:01 PM
Troll & Dark Elf - Londinium: splice frayed signal rope back into one continuous length. nervous precision and mutual trust.
Explore apps: https://alteredlineage.com/
#gamedev #indiegame #conceptart
Explore apps: https://alteredlineage.com/
#gamedev #indiegame #conceptart
I want to splice together two movies like a remix where dora the explorer grows up to be the tomb raider
November 11, 2026 at 3:36 PM
I want to splice together two movies like a remix where dora the explorer grows up to be the tomb raider
Splice in one of Roy Cohen, too, complete the set.
November 9, 2026 at 6:25 AM
Splice in one of Roy Cohen, too, complete the set.
(25mph until you cut two wires and splice in a 5-kOhm resistor)
November 10, 2026 at 8:09 PM
(25mph until you cut two wires and splice in a 5-kOhm resistor)
LMAOOO of course Splice made a fucking DAW. maybe they'll eventually go full circle and remake the version control sotware that was their original, namesake product
November 8, 2026 at 7:23 PM
LMAOOO of course Splice made a fucking DAW. maybe they'll eventually go full circle and remake the version control sotware that was their original, namesake product
Here’s a new beat I made with Splice’s Build a Stack mode 🔥 Check it out! 🎧
No.668 - Trancestep
#Splice #SpliceStack
No.668 - Trancestep
#Splice #SpliceStack
November 12, 2026 at 10:51 AM
Here’s a new beat I made with Splice’s Build a Stack mode 🔥 Check it out! 🎧
No.668 - Trancestep
#Splice #SpliceStack
No.668 - Trancestep
#Splice #SpliceStack