#Steroid-Dependent
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rayquazing.bsky.social
Being steroid dependent sucks ass let me tell you
May 16, 2026 at 8:11 PM
docgaby.bsky.social
Endometriose ist eine chronische, hormonabhängige Erkrankung, von der weltweit schätzungsweise 190 Millionen Frauen betroffen sind.

Das Ergebnis dieser Studie:

Endometriose ist durch veränderte Konzentrationen androgener Hormone gekennzeichnet
academic.oup.com/ejendo/artic...
Steroid hormone profiling reveals altered adrenal androgen production in endometriosis
AbstractObjective. Endometriosis is a chronic, hormone-dependent condition affecting an estimated 190 million women worldwide. Our understanding of hormona
academic.oup.com
July 10, 2026 at 8:23 PM
edgarvlermamd.medsky.network
Tacrolimus or Mycophenolate Mofetil for Frequently Relapsing or Steroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial ca. 2025
#NephJC #Nephpearls #FSGSAwarenessDay #NephSky

#VisualAbstract by @krithicism.bsky.social

👉 pubmed.ncbi.nlm.nih.gov/40354041/
June 11, 2025 at 1:20 AM
giorgioseano.bsky.social
New in Science Advances: Steroid-dependent metabolic rewiring in #Glioblastoma reveals novel therapeutic and imaging approaches. 🧠🔬

Honored to be involved in such a stimulating study!

Read here: www.science.org/doi/full/10....
Steroid-dependent metabolic rewiring reveals novel therapeutic and imaging approaches for glioblastoma
Dexamethasone reprograms glioblastoma nicotinamide metabolism, sensitizing tumors to methionine restriction and enabling PET.
www.science.org
January 27, 2026 at 1:19 PM
asouth-neph.bsky.social
Alright #PedNeph #NephTwitter ⁦‪#NephJC

What do you think?

Truly a comparative effectiveness trial?

Tacrolimus or Mycophenolate Mofetil for Frequently Relapsing or Steroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial

jamanetwork.com/journals/jam...
Tacrolimus or Mycophenolate Mofetil for Frequently Relapsing or Steroid-Dependent Nephrotic Syndrome
This randomized clinical trial conducted at 12 pediatric nephrology centers in China compares the effectiveness and safety of tacrolimus and mycophenolate mofetil in children with frequently relapsing...
jamanetwork.com
May 12, 2025 at 10:48 PM
skwinnicki.bsky.social
My guess would be physiological state dependent. Got enough resources for a spare mouth to feed? That prolactin care pathway is dominant and adoption is a reasonable outcome. Struggling to feed your own babies? Steroid stress/aggression pathways motivate snacking instead.
June 26, 2026 at 7:39 PM
nephjc.bsky.social
Abbreviations
TAC- Tacrolimus
CNI- calcineurin inhibitor
MMF- Mycophenolate mofetil
SSNS- steroid sensitive nephrotic syndrome
FRNS- frequently relapsing NS
SDNS- steroid dependent nephrotic syndrome
#NephJC
June 11, 2025 at 1:09 AM
sodatroubles.bsky.social
Long Term Evaluations of First Single-dose #Rituximab in Children with Steroid-Dependent Minimal-Change #Nephrotic Syndrome
#nephsky
www.tandfonline.com/doi/full/10....
Long Term Evaluations of First Single-dose Rituximab in Children with Steroid-Dependent Minimal-Change Nephrotic Syndrome
To explore the long-term efficacy and safety of the first single dose of rituximab in children with steroid-dependent minimal-change nephrotic syndrome (SD-MCNS) over a two-year period after infusi...
www.tandfonline.com
November 28, 2024 at 2:41 AM
aspneph.bsky.social
Case report: Belimumab combined with mycophenolate mofetil in a child with frequently relapsing, steroid-dependent nephrotic syndrome
#nephsky
Belimumab combined with mycophenolate mofetil in a child with frequently relapsing, steroid-dependent nephrotic syndrome - Pediatric Nephrology
Frequently relapsing, steroid-dependent nephrotic syndrome (FRNS/SDNS) remains a therapeutic challenge. Rituximab, a B-cell-depleting agent, is effective and widely used for FRNS/SDNS, but its use…
buff.ly
November 26, 2025 at 2:01 PM
drdeepaknmodi.bsky.social
March is Endometriosis Awareness Month
Here are some papers on endometriosis in mouse

Steroid receptors
pmc.ncbi.nlm.nih.gov/articles/PMC...

Estrogen
doi.org/10.1007/s120...
Inflamation
doi.org/10.1007/s120...
Hox genes
journals.lww.com/fsar/fulltex...

#ReproductiveBiology
Spatial and temporal changes in the expression of steroid hormone receptors in mouse model of endometriosis
Endometriosis is recognized as a steroid hormone-dependent disorder. However, controversies exist regarding the status of the steroid hormone receptor expression in endometriotic tissues. The purpose of this study was to determine the ontogeny of ...
pmc.ncbi.nlm.nih.gov
March 29, 2026 at 6:30 AM
gibsonlab.bsky.social
We're very excited about this work! Using steroid metabolome profiling we found a unique hormone signature that could be used as a potential non-invasive diagnostic test for endometriosis. Please check out and share the preprint #endometriosis www.medrxiv.org/content/10.1...
Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis
Endometriosis is a chronic, hormone-dependent condition that affects 190 million women worldwide. There are no validated biomarkers for endometriosis and this delays diagnosis and treatment. We perfo...
www.medrxiv.org
May 27, 2025 at 2:30 PM
bassoonysu.bsky.social
Apparently, all diabetics can! Including people with gestational diabetes, steroid-induced diabetes, and insulin-dependent Type 2!! What an expedient way to kill millions of people!!!
May 26, 2025 at 12:40 PM
jostflynnmd.bsky.social
Single (375 mg/m2) vs. double dose of rituximab along with mycophenolate mofetil for children with steroid-dependent/frequently relapsing nephrotic syndrome @ped-neph.bsky.social
rdcu.be/d45bN
December 28, 2024 at 3:10 PM
endocrineoncology.bsky.social
Read this review by Yasuhiro Miki et al. describing a visualisation method for elucidating steroid hormone signaling in #hormone-dependent #tumours using formalin-fixed paraffin-embedded tissues 👉 ow.ly/RBkV50Tcnmx
Endocrine Oncology logo and Figure 1. Estrogen receptor signals and corresponding histopathological analysis.
December 20, 2024 at 9:47 AM
jostflynnmd.bsky.social
B cell depletion with rituximab in children with steroid-sensitive nephrotic syndrome: does depletion duration change outcome? @ped-neph.bsky.social #nephsky #pedsky
link.springer.com/article/10.1...
B cell depletion with rituximab in children with steroid-sensitive nephrotic syndrome: does depletion duration change outcome? - Pediatric Nephrology
Background Rituximab (RTX) is widely used to prevent relapses in steroid-dependent or frequently-relapsing nephrotic syndrome (SD/FRNS). However, the impact of B-cell depletion duration on long-term o...
link.springer.com
March 23, 2026 at 1:17 AM
iamsammi.bsky.social
Same here, I am in Remmison for CLL & I have Addison disease, and I am Steroid dependent for life & I have not gotten COVID or the FLU!
Vaccines work!
November 22, 2024 at 6:12 PM
skwinnicki.bsky.social
Anyway check out our preprint, which is no longer AI summarized but you can read the summary by me, a human scientist who knows what my own research is. There is (admittedly) no lay summary, I typically do those after journal acceptance (this one's not there yet): www.biorxiv.org/content/10.1...
Yolk steroid concentrations decline in Japanese Quail (Coturnix japonica) eggs throughout incubation
The development of avian embryos is dependent not only on their genetic background but also on both external conditions and the maternal resources deposited into eggs. Specifically, maternally derived...
www.biorxiv.org
June 6, 2025 at 9:33 PM
nephjc.bsky.social
⏰ 60 minutes until #NephJC
💬 Today we dive into a pediatrics @jama.com article on the treatment of steroid sensitive nephrotic syndrome and the options for treatment in frequently relapsing and steroid dependent cases.
pmc.ncbi.nlm.nih.gov...
Tacrolimus or Mycophenolate Mofetil for Frequently Relapsing or Steroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial - PMC
Despite both tacrolimus (TAC) and mycophenolate mofetil (MMF) being recommended for children with steroid-sensitive but frequently relapsing nephrotic syndrome (FRNS) or steroid-dependent nephrotic syndrome (SDNS), their comparative efficacy and ...
pmc.ncbi.nlm.nih.gov
June 11, 2025 at 12:00 AM
thelancet.com
Monthly injection may help severe asthma patients safely reduce or stop daily oral steroid use, suggests new study in @lancetrespirmed.bsky.social

Explore the research 👉 spkl.io/63328Ae4di
Research in context panel for "Oral corticosteroid reduction and discontinuation in adults with corticosteroid-dependent, severe, uncontrolled asthma treated with tezepelumab (WAYFINDER): a multicentre, single-arm, phase 3b trial". Copyright: 2025 The Author(s). Published by Elsevier Ltd. CC BY 4.0
November 27, 2025 at 12:33 PM
nephjc.bsky.social
There was also a spectrum of ACTH-independent (post-DST) & ACTH-dependent (post ACTH-stim) production of aldosterone & its precursors. Not surprisingly, this was also observed in 18-hybrid steroid production, highlighting a spectrum of ACTH-mediated CYP11B2 activity. #NephJC
February 12, 2025 at 2:32 AM
addisonsdisease.bsky.social
What would be in your steroid dependent starter pack?

Living with Addison’s or adrenal insufficiency means carrying:
💳 Steroid emergency card
💉 Emergency hydrocortisone injection kit
💊 Spare medication
❗ Medic alert ID/jewellery

Learn more 👉 www.addisonsdisease.org.uk/newly-diagno... (1/2)
A blister-style pack titled “Steroid Dependent Essentials” displays essential items for people with Addison’s disease or adrenal insufficiency. The teal packaging contains a NHS Steroid Emergency Card, an Emergency Injection Kit, a box of Hydrocortisone 10 mg tablets, a strip of four white tablets, and a white Medic Alert bracelet. At the bottom, on a purple panel, it reads “Addison’s Disease Self-Help Group (ADSHG)” along with the website www.addisonsdisease.org.uk.
April 14, 2025 at 12:02 PM
aspneph.bsky.social
Mycophenolate mofetil versus tacrolimus for maintenance of remission in children with frequently relapsing and steroid-dependent nephrotic syndro…

link.springer.com/article/10.1...
#PedNeph #Nephrology
September 11, 2026 at 1:01 PM
nephjc.bsky.social
10/10
Final #Nephjc thoughts:
We love our peds colleagues! There are many challenges to treating GN without biopsies and ongoing uncertainty about the pathophysiology differences of relapsing or steroid dependent disease 😮‍💨
@shinamenon.bsky.social @rheaultm.bsky.social
June 25, 2025 at 3:10 PM