Read this interesting preprint from the lab of Krishnamurthy Natarajan: Cotranslational assembly confers specificity for in vivo target heterodimerization of paralogous H2B-like TAF12 proteins in the human fungal pathogen Candida albicans

doi: doi.org/10.1101/2025...

Finally, we asked whether loss of TADA1 would lead to collateral loss of other SAGA components, including its co-translational assembly partner TAF12. Indeed, using TMT proteomics we detected progressive depletion of several TADA1 neighbours in the CORE and HAT modules, including TAF12. 8/n

Histone Fold mediated heterodimerization specifies the selective association of TAF12 paralogs with TFIID and SAGA complexes in Candida albicans. https://www.biorxiv.org/content/10.64898/2026.02.06.704445v1

Histone Fold mediated heterodimerization specifies the selective association of TAF12 paralogs with TFIID and SAGA complexes in Candida albicans. https://www.biorxiv.org/content/10.64898/2026.02.06.704445v1

LncRNAs and bladder cancer. An intriguing read!

Exosomal lnc-TAF12–2:1 acts as a miR-7847–3p sponge, activating the miR-7847–3p/ASB12 regulatory axis and promoting #BladderCancer #tumorigenesis. #exosomes #lncRNAs #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

#DBfeature

TATA-binding associated factors have distinct roles during early mammalian development

"Taf5 and Taf12 mutants become lethal during peri-implantation stages, and Taf13 mutants fail to initiate gastrulation by E7.5."

by Xinjian He, Jesse Mager et al
www.sciencedirect.com/science/arti...

Authors published a paper in Biorxiv, they used ImageJ in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility

Fahrenthold does it again: Trump Foundation lacks the certification required for charities that solicit money http://wpo.st/taf12

The Art Of Fighting archivia un altro grande evento all'Allianz Cloud, e dà appuntamento al prossimo 23 maggio!

#TSOS // #TAF // #TAF12 // #TheArtOfFighting // #EBU // #FPI // #AllianzCloud // #Boxe // #Pugilato

Di rientro dalla rivincita contro Francesco Russo, Christian Mazzon punta ad affermarsi come campione italiano in due categorie, mentre Francesco Faraoni proverà a replicare quanto fatto dal fratello Mattia alcuni anni fa.

#TSOS // #TAF12 // #TAF // #TheArtOfFighting // #FPI // #Boxe // #Pugilato /

Cotranslational assembly confers specificity for in vivo target heterodimerization of paralogous H2B-like TAF12 proteins in the human fungal pathogen Candida albicans https://www.biorxiv.org/content/10.1101/2025.06.23.660276v1

Cotranslational assembly confers specificity for in vivo target heterodimerization of paralogous H2B-like TAF12 proteins in the human fungal pathogen Candida albicans https://www.biorxiv.org/content/10.1101/2025.06.23.660276v1

#Exosomal lnc-TAF12–2:1 is upregulated in #BladderCancer, driving proliferation by sponging miR-7847–3p to stabilize ASB12; its inhibition suppresses #tumorigenesis, positioning it as a novel diagnostic and therapeutic #biomarker.

#OpenAccess: doi.org/10.1016/j.ge...

This study elucidates the role of lnc-TAF12-2:1 in #BladderCancer (BCa) #Tumorigenesis, via the #miR-7847-3p/ASB12 axis, positioning lnc-TAF12–2:1 as a potential #MolecularTarget for #therapeutic intervention in BCa. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

LncRNAs and bladder cancer. An intriguing read!

Exosomal lnc-TAF12–2:1 acts as a miR-7847–3p sponge, activating the miR-7847–3p/ASB12 regulatory axis and promoting #BladderCancer #tumorigenesis. #exosomes #lncRNAs #medsky

#OpenAccess: www.sciencedirect.com/science/arti...