Еthno mosaic (2022) - Svitlana Lazareva (b.1987)
January 15, 2025 at 11:24 AM
Еthno mosaic (2022) - Svitlana Lazareva (b.1987)
wait what thNO NO YOU CANT DO THIS TO ME
December 25, 2025 at 3:32 AM
wait what thNO NO YOU CANT DO THIS TO ME
(F)ar (r)ight (e)thno (n)ationalist, ya that's him
January 3, 2025 at 2:05 AM
(F)ar (r)ight (e)thno (n)ationalist, ya that's him
So I was in a shoe store this morning trying on shoes. I said to the saleswoman, “This one’s too tight.”
“Try it with the tongue out,” she suggested.
“It'th thno goog, itth thill thoo tihhhth,” I replied.
“Try it with the tongue out,” she suggested.
“It'th thno goog, itth thill thoo tihhhth,” I replied.
February 22, 2025 at 5:10 AM
So I was in a shoe store this morning trying on shoes. I said to the saleswoman, “This one’s too tight.”
“Try it with the tongue out,” she suggested.
“It'th thno goog, itth thill thoo tihhhth,” I replied.
“Try it with the tongue out,” she suggested.
“It'th thno goog, itth thill thoo tihhhth,” I replied.
Fibroblasts⏫ #Lymphangiogenesis in transplanted heart🐭
BALB/c➡️C57BL/6J
Recipient pre-existing #LymphaticEndothelialCell➡️ 🫀allograft lymphangiogenesis
Ablation of Postn+ fibroblast (VEGFD Midline), or VEGFR3i➡️
⏬lymphangiogenesis
⏫allograft failure
#THNO 2024
www.thno.org/v14p1886.htm
BALB/c➡️C57BL/6J
Recipient pre-existing #LymphaticEndothelialCell➡️ 🫀allograft lymphangiogenesis
Ablation of Postn+ fibroblast (VEGFD Midline), or VEGFR3i➡️
⏬lymphangiogenesis
⏫allograft failure
#THNO 2024
www.thno.org/v14p1886.htm
May 24, 2025 at 12:23 PM
Fibroblasts⏫ #Lymphangiogenesis in transplanted heart🐭
BALB/c➡️C57BL/6J
Recipient pre-existing #LymphaticEndothelialCell➡️ 🫀allograft lymphangiogenesis
Ablation of Postn+ fibroblast (VEGFD Midline), or VEGFR3i➡️
⏬lymphangiogenesis
⏫allograft failure
#THNO 2024
www.thno.org/v14p1886.htm
BALB/c➡️C57BL/6J
Recipient pre-existing #LymphaticEndothelialCell➡️ 🫀allograft lymphangiogenesis
Ablation of Postn+ fibroblast (VEGFD Midline), or VEGFR3i➡️
⏬lymphangiogenesis
⏫allograft failure
#THNO 2024
www.thno.org/v14p1886.htm
#ArterioVenousMalformation
#HereditaryHemorrhagicTelangiectasia
Endothelial Cell KLF4 hyperactivation➡️
⏫EC Proliferation
⏬EC PDGFB➡️
⏬NG2+PDGFRβ+ Pericyte investment on AVM lesion
Evidence from
1⃣🐭 Retina +BMP9/10 Ab +EC Alk1 or Smad4 KO
2⃣HHT2👤 Nasal mucosa
#THNO 2026
www.thno.org/v16p4905.htm
#HereditaryHemorrhagicTelangiectasia
Endothelial Cell KLF4 hyperactivation➡️
⏫EC Proliferation
⏬EC PDGFB➡️
⏬NG2+PDGFRβ+ Pericyte investment on AVM lesion
Evidence from
1⃣🐭 Retina +BMP9/10 Ab +EC Alk1 or Smad4 KO
2⃣HHT2👤 Nasal mucosa
#THNO 2026
www.thno.org/v16p4905.htm
June 9, 2026 at 12:30 PM
#ArterioVenousMalformation
#HereditaryHemorrhagicTelangiectasia
Endothelial Cell KLF4 hyperactivation➡️
⏫EC Proliferation
⏬EC PDGFB➡️
⏬NG2+PDGFRβ+ Pericyte investment on AVM lesion
Evidence from
1⃣🐭 Retina +BMP9/10 Ab +EC Alk1 or Smad4 KO
2⃣HHT2👤 Nasal mucosa
#THNO 2026
www.thno.org/v16p4905.htm
#HereditaryHemorrhagicTelangiectasia
Endothelial Cell KLF4 hyperactivation➡️
⏫EC Proliferation
⏬EC PDGFB➡️
⏬NG2+PDGFRβ+ Pericyte investment on AVM lesion
Evidence from
1⃣🐭 Retina +BMP9/10 Ab +EC Alk1 or Smad4 KO
2⃣HHT2👤 Nasal mucosa
#THNO 2026
www.thno.org/v16p4905.htm
Fibulin 7⬇️ROCK-Actin filamentation-MRTFA cascade➡️⬇️aortic #SmoothMuscleCell contractile phenotype in🐭hypertension (Angiotensin II)
Syndecan 4 as a binding partner & signaling antagonist of FBLN7
i.v. AAV9-SM22α-FBLN7▶️persistent FBLN7 protein 1.5-fold⏫in🐭aorta
#THNO 2024
www.thno.org/v14p7569.htm
Syndecan 4 as a binding partner & signaling antagonist of FBLN7
i.v. AAV9-SM22α-FBLN7▶️persistent FBLN7 protein 1.5-fold⏫in🐭aorta
#THNO 2024
www.thno.org/v14p7569.htm
December 22, 2024 at 1:46 PM
Fibulin 7⬇️ROCK-Actin filamentation-MRTFA cascade➡️⬇️aortic #SmoothMuscleCell contractile phenotype in🐭hypertension (Angiotensin II)
Syndecan 4 as a binding partner & signaling antagonist of FBLN7
i.v. AAV9-SM22α-FBLN7▶️persistent FBLN7 protein 1.5-fold⏫in🐭aorta
#THNO 2024
www.thno.org/v14p7569.htm
Syndecan 4 as a binding partner & signaling antagonist of FBLN7
i.v. AAV9-SM22α-FBLN7▶️persistent FBLN7 protein 1.5-fold⏫in🐭aorta
#THNO 2024
www.thno.org/v14p7569.htm
Sock of the morning.
Socko has finally finished his lil project
Socko hopes u enjoy
And maybe
Just maybe
Put you into the Halloween spirit early
youtu.be/ThNO-Wtabgo?...
Socko has finally finished his lil project
Socko hopes u enjoy
And maybe
Just maybe
Put you into the Halloween spirit early
youtu.be/ThNO-Wtabgo?...
Socko Has Evolved!
YouTube video by Socko The Sock
youtu.be
September 19, 2025 at 2:46 PM
Sock of the morning.
Socko has finally finished his lil project
Socko hopes u enjoy
And maybe
Just maybe
Put you into the Halloween spirit early
youtu.be/ThNO-Wtabgo?...
Socko has finally finished his lil project
Socko hopes u enjoy
And maybe
Just maybe
Put you into the Halloween spirit early
youtu.be/ThNO-Wtabgo?...
#Tubulin #Angiogenesis
TUBB6 (β6V tubulin)
enriched in retinal #EndothelialCell #Pericyte
⏫in👤#AMD &🐭 #ChoroidNeoVascularization
Intravitreal siRNA Tubb6 ⏬ pathological angiogenesis in🐭 #OIR & 🐭laser CNV
YBX1 stabilizes TUBB6 ➡️
⏫Wnt3a/FZD8-Angiogenesis
#THNO 2025
www.thno.org/v15p2680.htm
TUBB6 (β6V tubulin)
enriched in retinal #EndothelialCell #Pericyte
⏫in👤#AMD &🐭 #ChoroidNeoVascularization
Intravitreal siRNA Tubb6 ⏬ pathological angiogenesis in🐭 #OIR & 🐭laser CNV
YBX1 stabilizes TUBB6 ➡️
⏫Wnt3a/FZD8-Angiogenesis
#THNO 2025
www.thno.org/v15p2680.htm
March 16, 2025 at 7:23 PM
#Tubulin #Angiogenesis
TUBB6 (β6V tubulin)
enriched in retinal #EndothelialCell #Pericyte
⏫in👤#AMD &🐭 #ChoroidNeoVascularization
Intravitreal siRNA Tubb6 ⏬ pathological angiogenesis in🐭 #OIR & 🐭laser CNV
YBX1 stabilizes TUBB6 ➡️
⏫Wnt3a/FZD8-Angiogenesis
#THNO 2025
www.thno.org/v15p2680.htm
TUBB6 (β6V tubulin)
enriched in retinal #EndothelialCell #Pericyte
⏫in👤#AMD &🐭 #ChoroidNeoVascularization
Intravitreal siRNA Tubb6 ⏬ pathological angiogenesis in🐭 #OIR & 🐭laser CNV
YBX1 stabilizes TUBB6 ➡️
⏫Wnt3a/FZD8-Angiogenesis
#THNO 2025
www.thno.org/v15p2680.htm
Single-cell transcriptomics #OxygenInducedRetinopathy #Angiogenesis
3 #Pericyte subsets
Col1a1 shRNA intravitreal P7 (onset of hyperoxia)▶️
⏬OIR avascular & neovascular tuft-like, SM α-actin+ mural cell-covered area
Also ⏬mural cell coverage of laser CNV
#THNO 2023
www.thno.org/v13p2515.htm
3 #Pericyte subsets
Col1a1 shRNA intravitreal P7 (onset of hyperoxia)▶️
⏬OIR avascular & neovascular tuft-like, SM α-actin+ mural cell-covered area
Also ⏬mural cell coverage of laser CNV
#THNO 2023
www.thno.org/v13p2515.htm
September 18, 2025 at 12:38 PM
Single-cell transcriptomics #OxygenInducedRetinopathy #Angiogenesis
3 #Pericyte subsets
Col1a1 shRNA intravitreal P7 (onset of hyperoxia)▶️
⏬OIR avascular & neovascular tuft-like, SM α-actin+ mural cell-covered area
Also ⏬mural cell coverage of laser CNV
#THNO 2023
www.thno.org/v13p2515.htm
3 #Pericyte subsets
Col1a1 shRNA intravitreal P7 (onset of hyperoxia)▶️
⏬OIR avascular & neovascular tuft-like, SM α-actin+ mural cell-covered area
Also ⏬mural cell coverage of laser CNV
#THNO 2023
www.thno.org/v13p2515.htm
#Atherosclerosis Epitranscriptomics
Cell type-specific dysregulation of m6A machinery in atherogenic phenotypes
#EndothelialCell ALKBH5
#SmoothMuscleCell WTAP
Mφ METTL3 YTHDF2
Re-analysis of scRNAseq Wirka's Nat Med 2019
pmc.ncbi.nlm.nih.gov/articles/PMC...
#THNO 2025
www.thno.org/v15p4785.htm
Cell type-specific dysregulation of m6A machinery in atherogenic phenotypes
#EndothelialCell ALKBH5
#SmoothMuscleCell WTAP
Mφ METTL3 YTHDF2
Re-analysis of scRNAseq Wirka's Nat Med 2019
pmc.ncbi.nlm.nih.gov/articles/PMC...
#THNO 2025
www.thno.org/v15p4785.htm
October 14, 2025 at 7:31 PM
#Atherosclerosis Epitranscriptomics
Cell type-specific dysregulation of m6A machinery in atherogenic phenotypes
#EndothelialCell ALKBH5
#SmoothMuscleCell WTAP
Mφ METTL3 YTHDF2
Re-analysis of scRNAseq Wirka's Nat Med 2019
pmc.ncbi.nlm.nih.gov/articles/PMC...
#THNO 2025
www.thno.org/v15p4785.htm
Cell type-specific dysregulation of m6A machinery in atherogenic phenotypes
#EndothelialCell ALKBH5
#SmoothMuscleCell WTAP
Mφ METTL3 YTHDF2
Re-analysis of scRNAseq Wirka's Nat Med 2019
pmc.ncbi.nlm.nih.gov/articles/PMC...
#THNO 2025
www.thno.org/v15p4785.htm
And now, the Ramones performing a medley of all of the “Best Song From a Movie” nominees at the 1995 MTV Movie Awards. youtu.be/5dCjfrLFRSs
Ramones Live At The MTV Awards 95
YouTube video by ThNo PuNk
youtu.be
July 3, 2025 at 1:00 AM
And now, the Ramones performing a medley of all of the “Best Song From a Movie” nominees at the 1995 MTV Movie Awards. youtu.be/5dCjfrLFRSs
¡ThN̶o mas!
December 22, 2024 at 5:24 AM
¡ThN̶o mas!
Differences is in insane thno
March 14, 2026 at 1:18 PM
Differences is in insane thno
Long overdue and probably a good time for distraction:
"Bluetorial" of our latest paper now published online in Theranostics. Congrats Skubal et al.!
📖 Read the full paper: doi.org/10.7150/thno...
"Bluetorial" of our latest paper now published online in Theranostics. Congrats Skubal et al.!
📖 Read the full paper: doi.org/10.7150/thno...
Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies
doi.org
February 9, 2025 at 12:44 AM
Long overdue and probably a good time for distraction:
"Bluetorial" of our latest paper now published online in Theranostics. Congrats Skubal et al.!
📖 Read the full paper: doi.org/10.7150/thno...
"Bluetorial" of our latest paper now published online in Theranostics. Congrats Skubal et al.!
📖 Read the full paper: doi.org/10.7150/thno...
New Book Review: Critical Issues in Head and Neck Oncology: Key Concepts from the Ninth THNO Meeting. www.jlo.co.uk/book-review/...
OpenAccess FullText available from @springernature.com
OpenAccess FullText available from @springernature.com
Critical Issues in Head and Neck Oncology: Key Concepts from the Ninth THNO Meeting - The Journal of Laryngology & Otology
Review by Patrick Bradley, Emeritus Professor Head and Neck Surgical Oncologist Nottingham University, Nottingham, UK This is the report of the proceeding of the Ninth Trends in Head and Neck Oncology...
www.jlo.co.uk
August 28, 2025 at 8:25 AM
New Book Review: Critical Issues in Head and Neck Oncology: Key Concepts from the Ninth THNO Meeting. www.jlo.co.uk/book-review/...
OpenAccess FullText available from @springernature.com
OpenAccess FullText available from @springernature.com
in my imagination he does a bit where hes the dentist asking questions and he yanks the models head to the side when he tries to respond to anything
So dyou like baseball? ThNO. YOU DONT TALK ITS DANGEROUS
So dyou like baseball? ThNO. YOU DONT TALK ITS DANGEROUS
July 7, 2025 at 9:36 PM
in my imagination he does a bit where hes the dentist asking questions and he yanks the models head to the side when he tries to respond to anything
So dyou like baseball? ThNO. YOU DONT TALK ITS DANGEROUS
So dyou like baseball? ThNO. YOU DONT TALK ITS DANGEROUS
Merry Xmas! youtu.be/Ucy4y3-Thno?...
Divine David on Christmas
YouTube video by WOWPresents
youtu.be
December 25, 2024 at 7:39 AM
Merry Xmas! youtu.be/Ucy4y3-Thno?...
As pessoas deveriam valorizar mais Ratos e o João.
o cara tem projeto social, tá sempre tentando ajudar.
e quase bateu no Dolabella, o que é notável.
eu adoro o João.
essa música é sensacional. Ele faz questão de cantar de forma mais clara.
eu amo essa música.
www.youtube.com/watch?v=lHc0...
o cara tem projeto social, tá sempre tentando ajudar.
e quase bateu no Dolabella, o que é notável.
eu adoro o João.
essa música é sensacional. Ele faz questão de cantar de forma mais clara.
eu amo essa música.
www.youtube.com/watch?v=lHc0...
Ratos de Porao [Sofrer]
YouTube video by ThNo PuNk
www.youtube.com
September 16, 2024 at 9:37 AM
As pessoas deveriam valorizar mais Ratos e o João.
o cara tem projeto social, tá sempre tentando ajudar.
e quase bateu no Dolabella, o que é notável.
eu adoro o João.
essa música é sensacional. Ele faz questão de cantar de forma mais clara.
eu amo essa música.
www.youtube.com/watch?v=lHc0...
o cara tem projeto social, tá sempre tentando ajudar.
e quase bateu no Dolabella, o que é notável.
eu adoro o João.
essa música é sensacional. Ele faz questão de cantar de forma mais clara.
eu amo essa música.
www.youtube.com/watch?v=lHc0...
Check out the Ramones singing movie theme songs at the MTV music awards. There is no way you can guess the next songs to be played. youtu.be/5dCjfrLFRSs?...
Ramones Live At The MTV Awards 95
YouTube video by ThNo PuNk
youtu.be
November 19, 2024 at 10:42 PM
Check out the Ramones singing movie theme songs at the MTV music awards. There is no way you can guess the next songs to be played. youtu.be/5dCjfrLFRSs?...