Single-cell sequencing of full-length transcripts and T-cell receptors with automated high-throughput Smart-seq3. #SingleCell #FullLengthRNA #TcellReceptor #Transcriptomics 🧬 🖥️
Single-cell sequencing of full-length transcripts and T-cell receptors with automated high-throughput Smart-seq3 - BMC Genomics
We developed an automated high-throughput Smart-seq3 (HT Smart-seq3) workflow that integrates best practices and an optimized protocol to enhance efficiency, scalability, and method reproducibility.…
bmcgenomics.biomedcentral.com
November 22, 2024 at 9:23 AM
Single-cell sequencing of full-length transcripts and T-cell receptors with automated high-throughput Smart-seq3. #SingleCell #FullLengthRNA #TcellReceptor #Transcriptomics 🧬 🖥️
#Medsky🧪#Immunosky New "TCR rules" dictate how a #Tcellreceptor (TCR) drives the differentiation of naive #Tcells into peripheral Tregs within the gut. In contrast to the traditional emphasis on environmental factors,
This is an interesting concept/expt: www.biorxiv.org/content/10.1...
www.biorxiv.org
October 21, 2025 at 1:48 PM
#Medsky🧪#Immunosky New "TCR rules" dictate how a #Tcellreceptor (TCR) drives the differentiation of naive #Tcells into peripheral Tregs within the gut. In contrast to the traditional emphasis on environmental factors,
www.science.org/doi/10.1126/...
T cells achieve precise antigen discrimination by relying on the temporal stability of #Tcellreceptor (TCR) interactions with antigens. Given that time is central to antigen discrimination,
T cells achieve precise antigen discrimination by relying on the temporal stability of #Tcellreceptor (TCR) interactions with antigens. Given that time is central to antigen discrimination,
Antigen affinity modulates ERK pulsing frequency during T cell activation
Real-time, single-cell imaging reveals ERK signaling dynamics in response to T cell receptor stimulation.
www.science.org
January 17, 2026 at 4:35 AM
www.science.org/doi/10.1126/...
T cells achieve precise antigen discrimination by relying on the temporal stability of #Tcellreceptor (TCR) interactions with antigens. Given that time is central to antigen discrimination,
T cells achieve precise antigen discrimination by relying on the temporal stability of #Tcellreceptor (TCR) interactions with antigens. Given that time is central to antigen discrimination,
#Antiverse #AI #AIantibodyplatform #biotech #drugdiscoveryprogrammes #antibodybasedtherapeutics #antibodies #drugtargets #Gproteincoupledreceptors #GPCR #ionchannels #NxeraPharma #GPCRs #cellularcommunication #transmembraneprotein #Tcellreceptor #TCR #antiPD1antibodies #drugdiscovery
zurl.co/cAKcg
zurl.co/cAKcg
Welsh firm Antiverse raises funds for AI antibody platform
Cardiff's Antiverse has raised $9.3m to develop its AI-based design platform for antibodies against hard-to-reach targets like GPCRs and ion channels.
pharmaphorum.com
March 9, 2026 at 3:43 PM
Excited to share WALTHAM’s paper in ImmunoHorizons. With Girihlet & Mars Advanced Research Institute, we characterised canine TCR repertoires. We revealed individual, breed & age-associated signatures, enabling immune monitoring, disease detection & intervention assessment. #TCellReceptor
The canine T cell receptor repertoire
AbstractBackground. Tseek is a method of sequencing T cell receptor (TCR) repertoires with minimal bias. This work aimed to develop methods to characterize
doi.org
August 26, 2025 at 10:47 AM
Excited to share WALTHAM’s paper in ImmunoHorizons. With Girihlet & Mars Advanced Research Institute, we characterised canine TCR repertoires. We revealed individual, breed & age-associated signatures, enabling immune monitoring, disease detection & intervention assessment. #TCellReceptor