The integrated transcriptomic cell atlas of human neural #organoids, Barbara Treutlein's lab, @fabiantheis.bsky.social @graycamplab.bsky.social @sergiuppasca.bsky.social @giorgiaquadrato.bsky.social and colleagues:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An integrated transcriptomic cell atlas of human neural organoids - Nature
A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...
www.nature.com
November 21, 2024 at 6:39 AM
The integrated transcriptomic cell atlas of human neural #organoids, Barbara Treutlein's lab, @fabiantheis.bsky.social @graycamplab.bsky.social @sergiuppasca.bsky.social @giorgiaquadrato.bsky.social and colleagues:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
New Transcriptomic Clock Unveils T Cell Aging in COVID,HIV
"Patients with acute COVID, they found two clear effects. First, COVID altered T cell composition, including significant reductions in naïve CD8 and naïve CD4 T cells. Second, the infection increased the biological age of naïve CD8 T cells"
"Patients with acute COVID, they found two clear effects. First, COVID altered T cell composition, including significant reductions in naïve CD8 and naïve CD4 T cells. Second, the infection increased the biological age of naïve CD8 T cells"
New Transcriptomic Clock Unveils T Cell Aging in COVID, HIV
These findings underscore the promise of single-cell transcriptomic biomarkers to disentangle the systemic and cell-intrinsic components of immune
www.miragenews.com
February 19, 2026 at 10:57 PM
New Transcriptomic Clock Unveils T Cell Aging in COVID,HIV
"Patients with acute COVID, they found two clear effects. First, COVID altered T cell composition, including significant reductions in naïve CD8 and naïve CD4 T cells. Second, the infection increased the biological age of naïve CD8 T cells"
"Patients with acute COVID, they found two clear effects. First, COVID altered T cell composition, including significant reductions in naïve CD8 and naïve CD4 T cells. Second, the infection increased the biological age of naïve CD8 T cells"
JCI Insight - Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson’s disease insight.jci.org/articles/vie...
JCI Insight -
Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson’s disease
insight.jci.org
July 10, 2025 at 8:32 PM
JCI Insight - Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson’s disease insight.jci.org/articles/vie...
🚨 New preprint from the lab! 🚨
Transcriptomic profiling identifies cellular and molecular transitions during Merkel cell regeneration www.biorxiv.org/content/10.6...
Transcriptomic profiling identifies cellular and molecular transitions during Merkel cell regeneration www.biorxiv.org/content/10.6...
Transcriptomic profiling identifies cellular and molecular transitions during Merkel cell regeneration
Skin exhibits a remarkable capacity for regeneration, which requires the coordinated reconstitution of diverse cell types and structures. Merkel cells are mechanosensory cells that detect gentle touch...
www.biorxiv.org
September 22, 2026 at 8:41 PM
🚨 New preprint from the lab! 🚨
Transcriptomic profiling identifies cellular and molecular transitions during Merkel cell regeneration www.biorxiv.org/content/10.6...
Transcriptomic profiling identifies cellular and molecular transitions during Merkel cell regeneration www.biorxiv.org/content/10.6...
New method for identifying the fine transcriptomic types of thousands of neurons recorded in vivo!
May 19, 2026 at 5:29 PM
New method for identifying the fine transcriptomic types of thousands of neurons recorded in vivo!
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Single-cell atlas of transcriptomic vulnerability across brain disorders - Nature
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorde...
www.nature.com
September 25, 2026 at 1:19 AM
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
From a gene’s single cell expression–through spatial localization–to novel function, and beyond!
Now out @natplants.nature.com
We built a comprehensive spatial-transcriptomic atlas of Arabidopsis, revealing cell-type identities across organs in unprecedented detail
www.nature.com/articles/s41...
Now out @natplants.nature.com
We built a comprehensive spatial-transcriptomic atlas of Arabidopsis, revealing cell-type identities across organs in unprecedented detail
www.nature.com/articles/s41...
A single-cell, spatial transcriptomic atlas of the Arabidopsis life cycle - Nature Plants
This study presents an extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents ten distinct developmental time points inclusive of six diverse organs.
www.nature.com
August 19, 2025 at 7:20 PM
From a gene’s single cell expression–through spatial localization–to novel function, and beyond!
Now out @natplants.nature.com
We built a comprehensive spatial-transcriptomic atlas of Arabidopsis, revealing cell-type identities across organs in unprecedented detail
www.nature.com/articles/s41...
Now out @natplants.nature.com
We built a comprehensive spatial-transcriptomic atlas of Arabidopsis, revealing cell-type identities across organs in unprecedented detail
www.nature.com/articles/s41...
Largest study on brain aging points to possible connections between diet, inflammation, and brain health. #Nature
"Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice"
Open Access
doi.org/10.1038/s415...
"Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice"
Open Access
doi.org/10.1038/s415...
Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice - Nature
A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional chan...
doi.org
January 2, 2025 at 12:45 AM
Largest study on brain aging points to possible connections between diet, inflammation, and brain health. #Nature
"Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice"
Open Access
doi.org/10.1038/s415...
"Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice"
Open Access
doi.org/10.1038/s415...
A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions.
Lots of updates from the preprint!
Lots of updates from the preprint!
Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates
Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.
www.science.org
September 17, 2025 at 7:31 PM
A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions.
Lots of updates from the preprint!
Lots of updates from the preprint!
A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
Single-cell profiling of the human endometrium in polycystic ovary syndrome - Nature Medicine
A transcriptomic atlas of the endometrium of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets.
go.nature.com
April 6, 2025 at 1:22 AM
A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
Nature research paper: Transcriptomic neuron types vary topographically in function and morphology
https://go.nature.com/40Z5QGm
https://go.nature.com/40Z5QGm
Transcriptomic neuron types vary topographically in function and morphology - Nature
Transcriptomic profiling of neurons from the zebrafish optic tectum identified more than 60 cell types; functional imaging revealed that response tuning, morphology and connectivity of specific cell types vary systematically with the neurons’ positions in the tissue.
go.nature.com
February 12, 2025 at 7:40 PM
Nature research paper: Transcriptomic neuron types vary topographically in function and morphology
https://go.nature.com/40Z5QGm
https://go.nature.com/40Z5QGm
Single-cell atlas of transcriptomic vulnerability across brain disorders idp.nature.com/authorize?re...
Single-cell atlas of transcriptomic vulnerability across brain disorders - Nature
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorde...
idp.nature.com
September 24, 2026 at 12:27 PM
Single-cell atlas of transcriptomic vulnerability across brain disorders idp.nature.com/authorize?re...
Super excited to share our Human Neural Organoid Atlas, now out in Nature! Led by @zhisonghe.bsky.social @josch1.bsky.social, and myself, this resource was created from 36 scRNA-seq datasets—totalling over 1.7 million cells! 🔬✨
www.nature.com/articles/s41...
Find out how it can serve you ⏬
🧵1/8
Find out how it can serve you ⏬
🧵1/8
An integrated transcriptomic cell atlas of human neural organoids - Nature
A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...
www.nature.com
November 21, 2024 at 10:11 AM
Super excited to share our Human Neural Organoid Atlas, now out in Nature! Led by @zhisonghe.bsky.social @josch1.bsky.social, and myself, this resource was created from 36 scRNA-seq datasets—totalling over 1.7 million cells! 🔬✨
www.nature.com/articles/s41...
Find out how it can serve you ⏬
🧵1/8
Find out how it can serve you ⏬
🧵1/8
Awesome gift to the research community: a compendium of transcriptomic data for the exploration of neocortical development—gene-level transcriptomic data from ~200(!!!) studies of neocortical development & in vitro models
Thanks @carlocolantuoni.bsky.social & colleagues 🙏
@natneuro.nature.com
🧪🧠
Thanks @carlocolantuoni.bsky.social & colleagues 🙏
@natneuro.nature.com
🧪🧠
NeMO Analytics: a compendium of transcriptomic data for the exploration of neocortical development - Nature Neuroscience
NeMO Analytics is a compendium of public transcriptomic data focused on the neocortex, enabling biologists without coding expertise to explore hundreds of datasets. Joint decomposition of these data y...
www.nature.com
March 26, 2026 at 6:37 AM
Awesome gift to the research community: a compendium of transcriptomic data for the exploration of neocortical development—gene-level transcriptomic data from ~200(!!!) studies of neocortical development & in vitro models
Thanks @carlocolantuoni.bsky.social & colleagues 🙏
@natneuro.nature.com
🧪🧠
Thanks @carlocolantuoni.bsky.social & colleagues 🙏
@natneuro.nature.com
🧪🧠
Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
September 11, 2025 at 5:50 PM
Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
The "transcriptomic chaos" preprint has been withdrawn by @mdpiopenaccess.bsky.social!
See here for more info: reeserichardson.blog/2025/07/28/n...
See here for more info: reeserichardson.blog/2025/07/28/n...
September 11, 2025 at 9:05 PM
The "transcriptomic chaos" preprint has been withdrawn by @mdpiopenaccess.bsky.social!
See here for more info: reeserichardson.blog/2025/07/28/n...
See here for more info: reeserichardson.blog/2025/07/28/n...
A paper in Nature presents the largest-known map of gene expression in the human prefrontal cortex region of the brain. go.nature.com/46BFtJZ 🧬🧪
September 23, 2026 at 10:25 PM
A paper in Nature presents the largest-known map of gene expression in the human prefrontal cortex region of the brain. go.nature.com/46BFtJZ 🧬🧪
A transcriptomic microglia taxonomy across mouse and human pathologies @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 26, 2026 at 2:17 AM
A transcriptomic microglia taxonomy across mouse and human pathologies @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nature research paper: Connectomics of predicted Sst transcriptomic types in mouse visual cortex
https://go.nature.com/43NhyqH
https://go.nature.com/43NhyqH
Connectomics of predicted Sst transcriptomic types in mouse visual cortex - Nature
The authors use Patch-seq and electron microscopy datasets to relate synaptic connectivity to the transcriptomic cell type of different types of inhibitory neuron.
go.nature.com
April 14, 2025 at 4:38 PM
Nature research paper: Connectomics of predicted Sst transcriptomic types in mouse visual cortex
https://go.nature.com/43NhyqH
https://go.nature.com/43NhyqH
Bit late with this, but super happy that our neural organoid atlas is out in Nature! Really fun collab with @zhisonghe.bsky.social and @le-and-er.bsky.social between the Treutlein lab, @fabiantheis.bsky.social and @graycamplab.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An integrated transcriptomic cell atlas of human neural organoids - Nature
A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...
www.nature.com
December 13, 2024 at 2:27 PM
Bit late with this, but super happy that our neural organoid atlas is out in Nature! Really fun collab with @zhisonghe.bsky.social and @le-and-er.bsky.social between the Treutlein lab, @fabiantheis.bsky.social and @graycamplab.bsky.social.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Our paper providing transcriptomic profiles of lateral septum (LS) cell types in human 🧠 is now online: www.cell.com/iscience/ful...
All data and code are publicly available online (links in the paper) and we provide an interactive web-based app to explore the data: libd.shinyapps.io/LS_snRNAseq/
All data and code are publicly available online (links in the paper) and we provide an interactive web-based app to explore the data: libd.shinyapps.io/LS_snRNAseq/
Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species
Neuroscience; Cellular neuroscience; Transcriptomics
www.cell.com
January 31, 2025 at 10:19 PM
Our paper providing transcriptomic profiles of lateral septum (LS) cell types in human 🧠 is now online: www.cell.com/iscience/ful...
All data and code are publicly available online (links in the paper) and we provide an interactive web-based app to explore the data: libd.shinyapps.io/LS_snRNAseq/
All data and code are publicly available online (links in the paper) and we provide an interactive web-based app to explore the data: libd.shinyapps.io/LS_snRNAseq/
New publication in Proceding of The Royal Society B!
"Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification"
royalsocietypublishing.org/rspb/article...
@cienciasulisboa.bsky.social @arnetla.bsky.social
"Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification"
royalsocietypublishing.org/rspb/article...
@cienciasulisboa.bsky.social @arnetla.bsky.social
December 17, 2025 at 3:33 PM
New publication in Proceding of The Royal Society B!
"Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification"
royalsocietypublishing.org/rspb/article...
@cienciasulisboa.bsky.social @arnetla.bsky.social
"Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification"
royalsocietypublishing.org/rspb/article...
@cienciasulisboa.bsky.social @arnetla.bsky.social
New OA Resource: "A single-cell, spatial transcriptomic atlas of the Arabidopsis life cycle" rdcu.be/eBmkU
An extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents 10 developmental time points in 6 diverse organs.
An extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents 10 developmental time points in 6 diverse organs.
August 19, 2025 at 10:36 AM
New OA Resource: "A single-cell, spatial transcriptomic atlas of the Arabidopsis life cycle" rdcu.be/eBmkU
An extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents 10 developmental time points in 6 diverse organs.
An extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents 10 developmental time points in 6 diverse organs.
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy - @jaweinst.bsky.social @uchicagopme.bsky.social go.nature.com/42hJ1Q2
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy - Nature Biotechnology
Volumetric DNA microscopy captures spatial information of RNA within an intact organism.
go.nature.com
March 27, 2025 at 3:09 PM
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy - @jaweinst.bsky.social @uchicagopme.bsky.social go.nature.com/42hJ1Q2