Expanding #SeizureForecasting: brain clock neurons modulate daily #Seizure susceptibility in #FruitFly model of #Epilepsy doi.org/10.1038/s414... @amitaseh @chronosleepinst #Drosophila #Neuroscience #TranslationalScience
Clock neurons modulate seizure timing through a diurnal switch - Nature Communications
Neural mechanisms that drive diurnal oscillations in seizure susceptibility are not fully understood. Here, in this manuscript, fruit flies show the daily rhythm of seizure risks, driven by brain cloc...
doi.org
November 3, 2026 at 5:40 PM
Expanding #SeizureForecasting: brain clock neurons modulate daily #Seizure susceptibility in #FruitFly model of #Epilepsy doi.org/10.1038/s414... @amitaseh @chronosleepinst #Drosophila #Neuroscience #TranslationalScience
#BrainRegion specific #transcriptional & #PostTranscriptional responses to #Electroconvulsive stimulation in #MouseBrain #SpatialTranscriptomics www.nature.com/articles/s41... @QiQiu8788 @hao_wu_7 #spatialNTseq #TranslationalScience
Spatial mapping of RNA turnover kinetics in the mouse brain - Nature Neuroscience
The authors developed spatial NT-seq to map the landscape of RNA turnover and stability regulation in the mouse brain, identifying the dentate gyrus as a turnover hotspot and revealing region-specific...
www.nature.com
November 6, 2026 at 2:00 PM
#BrainRegion specific #transcriptional & #PostTranscriptional responses to #Electroconvulsive stimulation in #MouseBrain #SpatialTranscriptomics www.nature.com/articles/s41... @QiQiu8788 @hao_wu_7 #spatialNTseq #TranslationalScience
Preparing an NIH R-grant?👀
Join the R-Award Fall Seminar Series for tips on creating clear, effective grant figures!
📅 Nov. 18
⏰ Noon–1:30 p.m. PT
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
Join the R-Award Fall Seminar Series for tips on creating clear, effective grant figures!
📅 Nov. 18
⏰ Noon–1:30 p.m. PT
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
Just over two weeks away! Researchers preparing NIH R-series applications are encouraged to join the next R-Award Fall Seminar Series session, “Visual Strategies for a More Compelling Grant.”
📅… | UC...
Just over two weeks away! Researchers preparing NIH R-series applications are encouraged to join the next R-Award Fall Seminar Series session, “Visual Strategies for a More Compelling Grant.”
📅 Novem...
www.linkedin.com
November 3, 2026 at 8:41 PM
Preparing an NIH R-grant?👀
Join the R-Award Fall Seminar Series for tips on creating clear, effective grant figures!
📅 Nov. 18
⏰ Noon–1:30 p.m. PT
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
Join the R-Award Fall Seminar Series for tips on creating clear, effective grant figures!
📅 Nov. 18
⏰ Noon–1:30 p.m. PT
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
Uncovering novel therapeutic strategy for targeting #BranchedChainAminoAcid #Transamination to sensitize #ClearCellRenalCellCarcinoma to #Glutaminase inhibition doi.org/10.1158/0008... @AranyLab #ccRCC #KidneyCancer #TranslationalScience
Targeting Branched-Chain Amino Acid Transamination Sensitizes Clear Cell Renal Cell Carcinoma to Glutaminase Inhibition
Abstract. Metabolic reprogramming is a well-described hallmark of clear cell renal cell carcinoma (ccRCC). Gene copy number variation and altered gene expression data suggest enhanced branched-chain a...
doi.org
October 29, 2026 at 6:46 PM
Uncovering novel therapeutic strategy for targeting #BranchedChainAminoAcid #Transamination to sensitize #ClearCellRenalCellCarcinoma to #Glutaminase inhibition doi.org/10.1158/0008... @AranyLab #ccRCC #KidneyCancer #TranslationalScience
Armoring #CARTcelltherapy with anti-inflammatory molecules offers new avenues for anti-fibrotic therapies in #ChronicKidneyDisease & other #Fibrosis conditions www.jci.org/articles/vie... @JonEpsteinLab #CellTherapy #CARTCell #TranslationalScience
www.jci.org
October 26, 2026 at 4:36 PM
Armoring #CARTcelltherapy with anti-inflammatory molecules offers new avenues for anti-fibrotic therapies in #ChronicKidneyDisease & other #Fibrosis conditions www.jci.org/articles/vie... @JonEpsteinLab #CellTherapy #CARTCell #TranslationalScience
Identifying ROR2 (receptor tyrosine kinase-like orphan receptor 2) as promising #DrugTarget to treat #RightVentricularFailure doi.org/10.1161/CIRC... #RVfailure #HeartFailure #Proteostasis #TranslationalScience
ROR2 Drives Right Ventricular Heart Failure Through Disruption of Proteostasis | Circulation
BACKGROUND: No therapies exist to reverse right ventricular failure (RVF), and the molecular mechanisms
that drive RVF remain understudied. We recently reported that the developmentally
restricted non...
doi.org
October 27, 2026 at 6:49 PM
Identifying ROR2 (receptor tyrosine kinase-like orphan receptor 2) as promising #DrugTarget to treat #RightVentricularFailure doi.org/10.1161/CIRC... #RVfailure #HeartFailure #Proteostasis #TranslationalScience
Keep up with recent and upcoming #translationalscience events at URochester in the latest Letter from the Co-Directors:
www.urmc.rochester.edu/clinical-tra...
#URochesterResearch
www.urmc.rochester.edu/clinical-tra...
#URochesterResearch
October 21, 2026 at 5:13 PM
Keep up with recent and upcoming #translationalscience events at URochester in the latest Letter from the Co-Directors:
www.urmc.rochester.edu/clinical-tra...
#URochesterResearch
www.urmc.rochester.edu/clinical-tra...
#URochesterResearch
#Chronotherapy in Translation doi.org/10.1146/annu... @elronan.bsky.social @FitzGerald__Lab #CircadianRhythms #DrugResponse #DrugMetabolism #PrecisionMedicine #Pharmacology #TranslationalScience
Circadian Rhythms in Drug Response: From Molecular Clocks to Precision Dosing
Circadian rhythms organize mammalian physiology across the 24-h day through molecular clocks coordinated by the central clock in the suprachiasmatic nucleus and distributed to peripheral oscillators. ...
doi.org
October 21, 2026 at 5:18 PM
#Chronotherapy in Translation doi.org/10.1146/annu... @elronan.bsky.social @FitzGerald__Lab #CircadianRhythms #DrugResponse #DrugMetabolism #PrecisionMedicine #Pharmacology #TranslationalScience
Applications are open for UC Davis CTSC's ACTIVATE K12 program, which supports early-career faculty through mentored research training and funding!
Virtual Q&A: Nov. 10, 3:30 p.m. PT
RSVP deadline: Oct. 30
For more information, please visit: lnkd.in/p/gMm-UGfi
#TranslationalScience
Virtual Q&A: Nov. 10, 3:30 p.m. PT
RSVP deadline: Oct. 30
For more information, please visit: lnkd.in/p/gMm-UGfi
#TranslationalScience
InfoReady | UC Davis Clinical and Translational Science Center
Call for Applications: CTSC ACTIVATE K12 Mentored Research Training Program! 🚨
The UC Davis Clinical and Translational Science Center (CTSC) is accepting applications for its Advancing Clinical and ...
lnkd.in
October 22, 2026 at 5:51 PM
Applications are open for UC Davis CTSC's ACTIVATE K12 program, which supports early-career faculty through mentored research training and funding!
Virtual Q&A: Nov. 10, 3:30 p.m. PT
RSVP deadline: Oct. 30
For more information, please visit: lnkd.in/p/gMm-UGfi
#TranslationalScience
Virtual Q&A: Nov. 10, 3:30 p.m. PT
RSVP deadline: Oct. 30
For more information, please visit: lnkd.in/p/gMm-UGfi
#TranslationalScience
Researchers: explore how fNIRS, physiological measurements and virtual reality can work together at a BIOPAC workshop featuring live demonstrations.
📅 Oct. 27
⏰ 10 a.m.–4:30 p.m. PT
📍 Betty Irene Moore Hall
Register: www.biopac.com/events/ws-br...
#TranslationalScience
📅 Oct. 27
⏰ 10 a.m.–4:30 p.m. PT
📍 Betty Irene Moore Hall
Register: www.biopac.com/events/ws-br...
#TranslationalScience
www.biopac.com
October 20, 2026 at 4:53 PM
Researchers: explore how fNIRS, physiological measurements and virtual reality can work together at a BIOPAC workshop featuring live demonstrations.
📅 Oct. 27
⏰ 10 a.m.–4:30 p.m. PT
📍 Betty Irene Moore Hall
Register: www.biopac.com/events/ws-br...
#TranslationalScience
📅 Oct. 27
⏰ 10 a.m.–4:30 p.m. PT
📍 Betty Irene Moore Hall
Register: www.biopac.com/events/ws-br...
#TranslationalScience
The Fall 2026 Comis #TranslationalScience Symposium continues with talks by Dr. Beatty of @penncancer.bsky.social & Dr. Gropler of @washumedicine.bsky.social #CancerResearch #Inflammation
October 20, 2026 at 5:20 PM
The Fall 2026 Comis #TranslationalScience Symposium continues with talks by Dr. Beatty of @penncancer.bsky.social & Dr. Gropler of @washumedicine.bsky.social #CancerResearch #Inflammation
The Comis #TranslationalScience Symposium concludes w/ a fantastic panel ft. Drs. Moghaddam & Kadara @utmdanderson.bsky.social, Dr. Cillo @upmchillmancc.bsky.social, Drs. Beatty & McDonald @penncancer.bsky.social, Dr. Gropler @washumedicine.bsky.social, & Dr. Mehnert @nyumedpostdocs.bsky.social
October 20, 2026 at 5:56 PM
The Comis #TranslationalScience Symposium concludes w/ a fantastic panel ft. Drs. Moghaddam & Kadara @utmdanderson.bsky.social, Dr. Cillo @upmchillmancc.bsky.social, Drs. Beatty & McDonald @penncancer.bsky.social, Dr. Gropler @washumedicine.bsky.social, & Dr. Mehnert @nyumedpostdocs.bsky.social
The Robert L. Comis, MD #TranslationalScience Symposium has begun with great talks on "#Inflammation as a Shared Mechanism Across Diseases" by Drs. Moghaddam & Kadara of @utmdanderson.bsky.social & Dr. Cillo of @upmchillmancc.bsky.social #eaonc
October 20, 2026 at 5:10 PM
The Robert L. Comis, MD #TranslationalScience Symposium has begun with great talks on "#Inflammation as a Shared Mechanism Across Diseases" by Drs. Moghaddam & Kadara of @utmdanderson.bsky.social & Dr. Cillo of @upmchillmancc.bsky.social #eaonc
Applications are open for NIH-supported training in neurotherapeutics discovery and development!
📅 March 23–26, 2027
⏳ Apply by Dec. 7
No tuition or registration fee for successful applicants.
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
📅 March 23–26, 2027
⏳ Apply by Dec. 7
No tuition or registration fee for successful applicants.
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
Neurotherapeutics Course | UC Davis Clinical and Translational Science Center
Applications are now open for the 2027 Training in Neurotherapeutics Discovery and Development for Academic Scientists! 🚨
This NIH-supported training program introduces academic researchers to the p...
www.linkedin.com
October 19, 2026 at 4:53 PM
Applications are open for NIH-supported training in neurotherapeutics discovery and development!
📅 March 23–26, 2027
⏳ Apply by Dec. 7
No tuition or registration fee for successful applicants.
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
📅 March 23–26, 2027
⏳ Apply by Dec. 7
No tuition or registration fee for successful applicants.
Details on LinkedIn: www.linkedin.com/feed/update/...
#TranslationalScience
#MyeloproliferativeNeoplasms: Unraveling mechanics of contradictory coexistence of #Thrombosis & #Hemorrhage doi.org/10.1126/scit... #JAK2V617F #MPN #TherapeuticOpportunities #TargetedTherapies #TranslationalScience
Aberrant erythrocyte rigidity in JAK2V617F myeloproliferative neoplasms underlies concurrent thrombosis and hemorrhage
Mouse and human myeloproliferative neoplasms expressing JAK2V617F mutation have stiff RBC membranes, which affects both thrombosis and hemostasis.
doi.org
October 15, 2026 at 6:05 PM
#MyeloproliferativeNeoplasms: Unraveling mechanics of contradictory coexistence of #Thrombosis & #Hemorrhage doi.org/10.1126/scit... #JAK2V617F #MPN #TherapeuticOpportunities #TargetedTherapies #TranslationalScience
Can Rebuilding Brain Hardware Restore Social Drive In Subjects?
Sources:
pubmed.ncbi.nlm.nih.gov/30626911/
#CognitiveBehavior #SocialDrive #NeuralRestoration #NeuroscienceData #BrainMechanisms #CircuitRepair #BehavioralScience #NSI189 #SevereAutism #PreclinicalTrials #TranslationalScience
Sources:
pubmed.ncbi.nlm.nih.gov/30626911/
#CognitiveBehavior #SocialDrive #NeuralRestoration #NeuroscienceData #BrainMechanisms #CircuitRepair #BehavioralScience #NSI189 #SevereAutism #PreclinicalTrials #TranslationalScience
October 12, 2026 at 2:31 PM
Can Rebuilding Brain Hardware Restore Social Drive In Subjects?
Sources:
pubmed.ncbi.nlm.nih.gov/30626911/
#CognitiveBehavior #SocialDrive #NeuralRestoration #NeuroscienceData #BrainMechanisms #CircuitRepair #BehavioralScience #NSI189 #SevereAutism #PreclinicalTrials #TranslationalScience
Sources:
pubmed.ncbi.nlm.nih.gov/30626911/
#CognitiveBehavior #SocialDrive #NeuralRestoration #NeuroscienceData #BrainMechanisms #CircuitRepair #BehavioralScience #NSI189 #SevereAutism #PreclinicalTrials #TranslationalScience
Clock-Dependent Organoid Maturation by Daily Metabolic Cycling by Juan Alvarez, PhD, Assistant Professor of Cell and Developmental Biology @juanalvarezdom.bsky.social @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 8, 2026 at 12:33 AM
Clock-Dependent Organoid Maturation by Daily Metabolic Cycling by Juan Alvarez, PhD, Assistant Professor of Cell and Developmental Biology @juanalvarezdom.bsky.social @PennMedicine #ITMATSymposium2026 #TranslationalScience
Welcome address by Garret A. FitzGerald MD, FRS, Director, ITMAT @FitzGerald__Lab @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:53 PM
Welcome address by Garret A. FitzGerald MD, FRS, Director, ITMAT @FitzGerald__Lab @PennMedicine #ITMATSymposium2026 #TranslationalScience
Welcome address by Jonathan Epstein, MD, Dean, Perelman School of Medicine, Executive Vice President @JonEpsteinLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:54 PM
Welcome address by Jonathan Epstein, MD, Dean, Perelman School of Medicine, Executive Vice President @JonEpsteinLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
Nucleoside-Modified mRNA-LNP Therapeutics by Drew Weissman, MD, PhD, Roberts Family Professor in Vaccine Research @WeissmanLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:55 PM
Nucleoside-Modified mRNA-LNP Therapeutics by Drew Weissman, MD, PhD, Roberts Family Professor in Vaccine Research @WeissmanLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
Advancing Genome Editing Therapies for Rare Diseases by Rebecca Ahrens-Nicklas, MD, PhD, Associate Professor of Pediatrics@@AhrensNicklas @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:56 PM
Advancing Genome Editing Therapies for Rare Diseases by Rebecca Ahrens-Nicklas, MD, PhD, Associate Professor of Pediatrics@@AhrensNicklas @PennMedicine #ITMATSymposium2026 #TranslationalScience
From Fantasy to Reality: Harnessing Genes to Reverse Blindness by Jean Bennett, MD, PhD, F.M. Kirby Professor Emerita, Ophthalmology @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:57 PM
From Fantasy to Reality: Harnessing Genes to Reverse Blindness by Jean Bennett, MD, PhD, F.M. Kirby Professor Emerita, Ophthalmology @PennMedicine #ITMATSymposium2026 #TranslationalScience
mRNA CAR T Cells to Treat Fibrosis by Jonathan Epstein, MD, Dean, Perelman School of Medicine, Executive Vice President @JonEpsteinLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 7, 2026 at 11:56 PM
mRNA CAR T Cells to Treat Fibrosis by Jonathan Epstein, MD, Dean, Perelman School of Medicine, Executive Vice President @JonEpsteinLab @PennMedicine #ITMATSymposium2026 #TranslationalScience
Outsmarting the Escape Artist: Resistance to CART Immunotherapies for Lymphoid Malignancies by Marco Ruella, MD, Associate Professor of Medicine @MarcoRuella @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 8, 2026 at 12:04 AM
Outsmarting the Escape Artist: Resistance to CART Immunotherapies for Lymphoid Malignancies by Marco Ruella, MD, Associate Professor of Medicine @MarcoRuella @PennMedicine #ITMATSymposium2026 #TranslationalScience
Reception and Dinner: The College of Physicians of Philadelphia with Dinner Discussant:
Norman J. Ornstein Retired Scholar, American Enterprise Institute @NormOrnstein @PennMedicine #ITMATSymposium2026 #TranslationalScience
Norman J. Ornstein Retired Scholar, American Enterprise Institute @NormOrnstein @PennMedicine #ITMATSymposium2026 #TranslationalScience
October 8, 2026 at 12:08 AM
Reception and Dinner: The College of Physicians of Philadelphia with Dinner Discussant:
Norman J. Ornstein Retired Scholar, American Enterprise Institute @NormOrnstein @PennMedicine #ITMATSymposium2026 #TranslationalScience
Norman J. Ornstein Retired Scholar, American Enterprise Institute @NormOrnstein @PennMedicine #ITMATSymposium2026 #TranslationalScience