Chen Liang and Li Dali's teams engineered smACGmax, a tri-base editor fusing deaminases and glycosylases inside Cas9 to achieve up to 41% simultaneous A, C, and G editing for multi-residue saturation screening. 🧬🤖 #BaseEditing #CRISPR #NatureComms2026 #TriBaseEditor #DirectedEvolution #Genomics
July 31, 2026 at 7:37 AM
Chen Liang and Li Dali's teams engineered smACGmax, a tri-base editor fusing deaminases and glycosylases inside Cas9 to achieve up to 41% simultaneous A, C, and G editing for multi-residue saturation screening. 🧬🤖 #BaseEditing #CRISPR #NatureComms2026 #TriBaseEditor #DirectedEvolution #Genomics