#UBASH3B
Online this week ➡️ Pharmacological inhibition of #UBASH3B induces #MitoticArrest and selectively reduces #TumorGrowth

By E. Pangou, @sumaralab.bsky.social and colleagues @igbmc.bsky.social

🗞️ doi.org/10.1038/s44321-026-00519-0
September 25, 2026 at 12:58 PM
Very proud of our new publication in EMBO Molecular Medicine 🥳, where we describe an antimitotic that selectively inhibits tumor growth without affecting normal tissues.

Big congratulations to Eva Pangou, Sushil Awal, Ksenia Krupina and all authors, and many thanks to our amazing collaborators! 🔬🥳
Pharmacological inhibition of UBASH3B induces mitotic arrest and selectively reduces tumor growth - EMBO Molecular Medicine
Cancer cells tolerate mitotic errors to sustain proliferation, yet the molecular dependencies enabling this tolerance remain poorly understood and largely unexploited therapeutically. UBASH3B ensures ...
link.springer.com
September 22, 2026 at 8:46 PM