#UniProt
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intact-ebi.bsky.social
IntAct release 253 is out! 1,814,919 binary interactions from 24,076 manually curated publications www.ebi.ac.uk/intact/about... (in sync with UniProt release 2026_02)
IntAct Portal
EMBL-EBI
www.ebi.ac.uk
November 3, 2026 at 11:01 AM
complexportal.bsky.social
🎉 Complex Portal release 253 is out! 🎉

5,368 manually curated biological complexes are now live, in sync with UniProt 2026_02

Highlights by species:
🧬 Homo sapiens – 2,534
🐁 Mus musculus – 753
🧫 Saccharomyces cerevisiae – 649
🪰 Drosophila melanogaster – 277

Explore: www.ebi.ac.uk/complexporta...
November 3, 2026 at 11:13 AM
soodoku.bsky.social
paperclip.gxl.ai
Paperclip
Paperclip — search, read, and analyze 11M+ biomedical papers, regulatory documents, clinical trials, and biological databases (UniProt, PDB, ChEMBL) from the command line.
paperclip.gxl.ai
November 4, 2026 at 6:15 PM
dabiophysicist.bsky.social
Some of the reports sound like non-GMP peptides apparently chosen on little more than Uniprot annotations...even if they're mostly inactive given form/route, people are going to get blood diseases.
October 30, 2026 at 1:02 AM
rridrobot.bsky.social
Authors published a paper in Biorxiv, they used UniProt in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #reproducibility #STMpublishing
www.biorxiv.org
November 2, 2026 at 1:00 PM
rridrobot.bsky.social
Authors published a paper in Biorxiv, they used UniProt in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #RRID #STMpublishing
www.biorxiv.org
November 1, 2026 at 1:00 PM
bigearthdata.ai
Structural basis for N-glycopeptide preference in an infant-derived Bifidobacterium bifidum PNGaseA
->Nature | More on "Bacterial enzyme N-glycan utilization discovery" at BigEarthData.ai
Structural basis for N-glycopeptide preference in an infant-derived Bifidobacterium bifidum PNGaseA
A rare PNGaseA-family enzyme in infant-associated B. bifidum To investigate N-glycan utilisation by species of human-associated Bifidobacterium species, InterPro, UniProt and IMG databases were screened for putative PNGase-encoding sequences, and this resulted in the identification of a predicted PNGase gene present in the genome of Bifidobacterium bifidum LMG13195 (the enzyme is denoted here as PNGaseABif, while its corresponding gene is referred to here as pngaseAbif)19,20,21. Intriguingly, PNGaseABif belongs to the PNGaseA superfamily, which is not currently associated with nutrient acquisition in bacterial species19. In the InterPro database, the current putative PNGaseA superfamily members are present in 1404, 710 and 94, eukaryotic, bacterial and archaeal species, respectively19. Within the eukaryotes, 1009 species are fungi (mainly Ascomycota and Basidiomycota), 311 species are flowering plants, while the remainder currently represent unclassified species. Within bacteria, 571 of the species with a putative PNGaseA-encoding sequence are Actinobacteria, where 444 of these are species of Streptomyces. The rest of the bacterial species represent a wide variety of microorganisms that are members of the Pseudomonadati kingdom. Of these bacterial sequences, there is only one additional putative PNGaseA enzyme (other than that specifying PNGaseABif) associated with a member of the Bifidobacterium genus, Bifidobacterium leontopitheci (A0A6I1GFR2) isolated from Golden-headed...
www.nature.com
November 2, 2026 at 11:15 AM
rridrobot.bsky.social
Authors published a paper in Biorxiv, they used UniProt in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #STMpublishing
www.biorxiv.org
October 28, 2026 at 12:00 PM
rridrobot.bsky.social
Authors published a paper in Biorxiv, they used UniProt in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #OpenScience #RRID
A clinically annotated proteomic and histological resource of 1,000 colorectal cancers
www.biorxiv.org
October 27, 2026 at 12:00 PM
training.ebi.embl.org
Explore how different types of protein functional and structural data can be accessed and connected across the @ebi.embl.org resources: UniProt, EMDB, Protein Data Bank in Europe, and the AlphaFold Protein Structure Database in our 11 Nov webinar.

Register for free: www.ebi.ac.uk/training/eve...

🧬
EMBL-EBI Training. Exploring proteins in infection biology with EMBL-EBI resources. 11 November 2026. 14:30 - 15:30 UK time. Speakers Stephanie Lo, Protein Function Content Leader, EMBL-EBI. And Kyle Morris, EMDB Team Leader at EMBL-EBI. Speaker Marcelo Querino, Data access and delivery lead at EMBL-EBI. Registration is free but required for each webinar in the series you would like to attend. www.ebi.ac.uk/training
October 26, 2026 at 9:19 AM
everydevai.bsky.social
Wiring an LLM to PubMed, UniProt and ChEMBL one API at a time gets old fast. ToolUniverse from gives any LLM one interface to 1,000+ scientific tools, models and databases through a native MCP server, a Python SDK and a tu CLI. It works with Claude Code, Cursor, Gemini CLI and Windsurf. Open...
October 24, 2026 at 12:31 AM
jalview.bsky.social
Customise Jalview's sequence ID tooltip by selecting View ➡️ Sequence ID Tooltip. Database references from @ebi.embl.org UniProt, EMBLCDS and ENSEMBL can then be shown in the tooltip if required — and accessed from Jalview using the 'Link' option.

🧮 Download Jalview: www.jalview.org/download/
October 23, 2026 at 11:30 AM
rridrobot.bsky.social
Authors published a paper in Biorxiv, they used UniProt in the study. Including #RRIDs will make this less ambiguous.

SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #RRID #OpenScience
www.biorxiv.org
October 24, 2026 at 12:00 PM
everydevai.bsky.social
Stitching together Ensembl, NCBI, UniProt and BLAST scripts just to look up one gene? gget (@scverse.bsky.social) from runs genomic database queries as single-line commands, from the command line or Python. It fetches sequences, runs BLAST, BLAT, MUSCLE and DIAMOND, and pulls CELLxGENE count...
October 23, 2026 at 3:28 PM
elixir-europe.org
💾 For #OAWeek and its theme “The cost of value”, ELIXIR wants to highlight 💡 evidence of the benefits that open science delivers. A PathOS case study involving ELIXIR demonstrated the value and impact of #UniProt: https://loom.ly/Rcpa8cU

#OpenScience #ResearchInfrastructure
October 21, 2026 at 8:45 AM
biohackrxiv.fediscience.org.ap.brid.gy
"DBCLS BioHackathon 2026 report: Mass spectrometry data analysis workflow and visualization towards trans-omics research" https://doi.org/10.37044/osf.io/76thg_v1

#bh26jp #biohackathon

"Finally, we investigated the interoperability of MB-POST with the […]

[Original post on fediscience.org]
Figure 2: Metaproteome visualization. (Top left) Per-sample UniProt Pathway class composition, grouped by sample category. (Top right) Group comparison of mean pathway composition. (Bottom) Pathways by phylum for a single sample. Bars show the share of all mapped PSMs; cells show the share of each phylum’s own mapped PSMs (darker is larger, scaled per level). Phylum assignments are taken from the eggNOG lineage of each protein. Pathway distributions are thus linked to the phyla contributing the detected proteins.
October 21, 2026 at 12:28 PM
loicaroyer.bsky.social
Click an image to open it at full resolution with its ZFIN metadata: anatomy terms, probe and quality rating, human orthologs and associated diseases. Each image links back to its ZFIN record. Any view can be shared as a URL, and the table exports as a PNG.
gene2fish image viewer: a full-resolution photo of a cxcr4a-stained embryo at the 1-4 somite stage, with labelled structures, next to its ZFIN information: gene, stage, anatomy terms, probe and quality rating, fish line, publication, human orthologs, diseases and UniProt links. Embryo images: Thisse et al., via ZFIN, CC BY 4.0.
October 21, 2026 at 4:03 AM
evgenii-protasov.bsky.social
UniProt data pruning and the growing invisibility of the dark proteome
#proteomics #bioinformatics #genomes
doi.org/10.1093/narg...
UniProt data pruning and the growing invisibility of the dark proteome
Abstract. The protein resource UniProtKB has undergone a major, multi-stage reorganization of its protein space, implemented from release 2025_04 through r
doi.org
October 18, 2026 at 10:34 AM
biomics-twinning.bsky.social
🧬 From Data to Discovery!

On 9 October, @biomics-twinning.bsky.social welcomed @ebi.embl.org experts to @gimminstitute.bsky.social for a full day of #UniProt training with 15 participants, a Biomedical Data Science Seminar and a new BIOMICS Friends interview! 🎥
#BIOMICS #UniProt #Bioinformatics
October 16, 2026 at 3:09 PM
pacyc184.bsky.social
UniProt data pruning and the growing invisibility of the dark proteome | NAR Genomics and Bioinformatics | Oxford Academic
UniProt data pruning and the growing invisibility of the dark proteome
Abstract. The protein resource UniProtKB has undergone a major, multi-stage reorganization of its protein space, implemented from release 2025_04 through r
dx.doi.org
October 16, 2026 at 5:02 AM
I am very pleased to represent @SIB and #uniprot at the Swiss Linked Data Day 2026 https://www.bfh.ch/de/aktuell/fachveranstaltungen/linked-data-day-2026/. There is a fantastic line-up of co-speakers.
Linked Data Day 2026
Der Linked Data Day ist eine jährliche Konferenz des Schweizerischen Bundesarchivs, die in Zusammenarbeit mit dem Institut Public Sector Transformation der BFH Wirtschaft organisiert wird.
www.bfh.ch
October 16, 2026 at 6:03 AM
metallab.ai
구글 딥마인드, 항균 펩타이드 탐색 사례 공개

구글 딥마인드가 Google Antigravity의 AI 에이전트와 연구자가 한 세션에서 새 항균 펩타이드 후보를 찾아낸 사례를 공개했다. UniProt의 기능 미상 단백질을 ProtNLM으로 훑어 고른 박테리오신 후보는 지금 습식 실험 검증을 받고 있다.
구글 딥마인드, 항균 펩타이드 탐색 사례 공개
구글 딥마인드가 Google Antigravity의 AI 에이전트와 연구자가 한 세션에서 새 항균 펩타이드 후보를 찾아낸 사례를 공개했다. UniProt의 기능 미상 단백질을 ProtNLM으로 훑어 고른 박테리오신 후보는 지금 습식 실험 검증을 받고 있다.
metallab.ai
October 15, 2026 at 8:31 PM
realfeedapp.com
The Google Antigravity platform unified millions of proteins in the UniProt database to rapidly identify new antibiotics. The ProtNLM model predicted the peptide's activity against respiratory tract pathogens.

#AntimicrobialResistance #GoogleAntigravity #Protnlm
Google Antigravity accelerates antimicrobial peptide discovery
Source: Google DeepMind blog
realfeedapp.com
October 15, 2026 at 6:00 PM
rdmpage.bsky.social
There are also 1.56 million citations for data from UniProt, RefSeq, Ensembl, Pfam and Cellosaurus that are ALL treated as "secondary", that is, reuse, not "primary" which is when a paper published the dataset. This looks arbitrary, and demonstrably false (e.g. www.cellosaurus.org/CVCL_A9V7)
Cellosaurus cell line GSC#393 (CVCL_A9V7)
$id in Cellosaurus, a cell line database, cell line catalogue, cell line ontology
www.cellosaurus.org
October 15, 2026 at 6:06 PM
moleculemaker.bsky.social
New in Nucleic Acids Research: CLEAN Database, with 55M+ AI-predicted enzyme functions across ~1.1M strains, plus an ESM-2 mutation-effect explorer with heatmaps and 3D views. Free, no login.
Congratulations, Le Yuan, Huimin Zhao and team at Illinois! doi.org/10.1093/nar/... #AIforScience #synbio
Graphical abstract of the CLEAN Database, showing how protein sequences from UniProt are annotated with enzyme functions by the CLEAN AI model and explored through a web interface with search and mutation-effect tools.
October 15, 2026 at 9:03 PM