Happy New Year from the Rubin Lab! 🎇
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing
Whole-genome screening reveals strategies to boost CRISPR-associated transposase genome editing efficiency.
www.science.org
January 5, 2026 at 6:45 PM
Happy New Year from the Rubin Lab! 🎇
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
New in Science Magazine Science Advances from the Doudna Lab, Rubin Lab and Cress Lab —Identification of proteins influencing #CRISPR-associated #transposases for enhanced #GenomeEditing. Read here: https://ow.ly/U0s450XS82n
January 5, 2026 at 7:23 PM
New in Science Magazine Science Advances from the Doudna Lab, Rubin Lab and Cress Lab —Identification of proteins influencing #CRISPR-associated #transposases for enhanced #GenomeEditing. Read here: https://ow.ly/U0s450XS82n
#VchCAST Meets λ-Red: Unlocking High-Efficiency Bacterial #GenomeEngineering 🧬🔬
Latest in Science Advances: A tour de force in identifying host-gatekeepers of VchCAST transposition. 🧪✨
Results: - E. coli: 55.2-fold increase.
Klebsiella: 10.8-fold increase.
Pseudomonas: 5.6-fold increase.
Latest in Science Advances: A tour de force in identifying host-gatekeepers of VchCAST transposition. 🧪✨
Results: - E. coli: 55.2-fold increase.
Klebsiella: 10.8-fold increase.
Pseudomonas: 5.6-fold increase.
April 12, 2026 at 8:02 AM
#VchCAST Meets λ-Red: Unlocking High-Efficiency Bacterial #GenomeEngineering 🧬🔬
Latest in Science Advances: A tour de force in identifying host-gatekeepers of VchCAST transposition. 🧪✨
Results: - E. coli: 55.2-fold increase.
Klebsiella: 10.8-fold increase.
Pseudomonas: 5.6-fold increase.
Latest in Science Advances: A tour de force in identifying host-gatekeepers of VchCAST transposition. 🧪✨
Results: - E. coli: 55.2-fold increase.
Klebsiella: 10.8-fold increase.
Pseudomonas: 5.6-fold increase.