#VeinAging
Great saphenous vein 18~89 y/o

Normal
👉Subintimal longitudinal #SmoothMuscleCell bundle peak at middle age
👉Outer medial longitudinal SMC bundle ⬆️with Age

Varicose
👉Alternating zones of hypertrophic & atrophic SMCs
👉Excess collagen deposit

#JCM_MDPI 2025
www.mdpi.com/2077-0383/14...