Thankyou. A fantastic article. #mastcells are responsible for the #visceralhypersensitivity we see in #IBS and #IBD. Antihistamines and mast cell stabilizers should be part of every gastro’s most used meds. Why amitryltiline works, it is an antihistamine.
Mast cell modulation: A novel therapeutic strategy for abdominal #pain in #IBD irritable bowel syndrome
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 18, 2024 at 11:10 AM
Thankyou. A fantastic article. #mastcells are responsible for the #visceralhypersensitivity we see in #IBS and #IBD. Antihistamines and mast cell stabilizers should be part of every gastro’s most used meds. Why amitryltiline works, it is an antihistamine.
🧠💩 Pain in the Gut: Fusobacterium varium bacteria triggers IBS symptoms by hijacking Piezo2 signaling #GutMicrobiome #Piezo2 #VisceralHypersensitivity #Neurogastroenterology pmc.ncbi.nlm.nih.gov/articles/PMC...
Mechanosensory Piezo2 regulated by gut microbiota participates in the development of visceral hypersensitivity and intestinal dysmotility
The gut microbiota plays a crucial role in the manifestation of intestinal dysfunction associated with irritable bowel syndrome (IBS). The mechanosensory Piezo2 has been implicated in the regulation o...
pmc.ncbi.nlm.nih.gov
June 13, 2025 at 7:24 PM
🧠💩 Pain in the Gut: Fusobacterium varium bacteria triggers IBS symptoms by hijacking Piezo2 signaling #GutMicrobiome #Piezo2 #VisceralHypersensitivity #Neurogastroenterology pmc.ncbi.nlm.nih.gov/articles/PMC...