Our #RStats / @bioconductor.bsky.social 📦 provides a framework for stitching together multiple #Visium @10xgenomics.bsky.social capture areas together
#AcademicSky
doi.org/10.1186/s128...
Our #RStats / @bioconductor.bsky.social 📦 provides a framework for stitching together multiple #Visium @10xgenomics.bsky.social capture areas together
#AcademicSky
doi.org/10.1186/s128...
doi.org/10.1101/2025...
#spatialtranscriptomics #visium #visiumhd #seurat #giotto
doi.org/10.1101/2025...
#spatialtranscriptomics #visium #visiumhd #seurat #giotto
13 vs. 20 clusters. And qualitatively different results, corroborating what we saw in biorxiv.org/content/10.1...
13 vs. 20 clusters. And qualitatively different results, corroborating what we saw in biorxiv.org/content/10.1...
Manifold Gromov-Wasserstein vs moscot SCOTv2 SpatialMeta
Visium + Xenium
Visium + #MassSpecImaging spatial metabolomics
Admit I have0️⃣understanding of the mathematical machinery😅
bioRxiv 2025
www.biorxiv.org/content/10.6...
Manifold Gromov-Wasserstein vs moscot SCOTv2 SpatialMeta
Visium + Xenium
Visium + #MassSpecImaging spatial metabolomics
Admit I have0️⃣understanding of the mathematical machinery😅
bioRxiv 2025
www.biorxiv.org/content/10.6...
Clever experimental design by @breinigmarco.bsky.social hijacking Visium and elegant analysis by @lomakinai.bsky.social and @elihei.bsky.social
www.nature.com/articles/s41...
Clever experimental design by @breinigmarco.bsky.social hijacking Visium and elegant analysis by @lomakinai.bsky.social and @elihei.bsky.social
www.nature.com/articles/s41...
Nice #Rstats pkg from @jef.works. Vignettes for SpatialExperiment + Visium scRNA-seq data
Nice #Rstats pkg from @jef.works. Vignettes for SpatialExperiment + Visium scRNA-seq data
SpaBatch
Align multi-slice sequencing-based spatial data
Visium ST Stereo-seq
#VariationalGraphAutoEncoder
Masked data augmentation
vs STG3Net STAligner SEDR DeepST SpaGIC STitch3D
bioRxiv 2025
www.biorxiv.org/content/10.1...
SpaBatch
Align multi-slice sequencing-based spatial data
Visium ST Stereo-seq
#VariationalGraphAutoEncoder
Masked data augmentation
vs STG3Net STAligner SEDR DeepST SpaGIC STitch3D
bioRxiv 2025
www.biorxiv.org/content/10.1...
Gradient Analysis of #Spatialtranscriptomics Organization with Neural networks
"models gene expression as a Piecewise linear function of the Isodepth"
Work with Visium Xenium MERFISH Slide-seq V2 Stereo-seq
@uthsav.bsky.social @naturemethods.bsky.social 2025
www.nature.com/articles/s41...
Gradient Analysis of #Spatialtranscriptomics Organization with Neural networks
"models gene expression as a Piecewise linear function of the Isodepth"
Work with Visium Xenium MERFISH Slide-seq V2 Stereo-seq
@uthsav.bsky.social @naturemethods.bsky.social 2025
www.nature.com/articles/s41...
📄 www.nature.com/articles/s41...
#SpatialTranscriptomics #CancerResearch cc: @owkin.bsky.social @10xgenomics.bsky.social
📄 www.nature.com/articles/s41...
#SpatialTranscriptomics #CancerResearch cc: @owkin.bsky.social @10xgenomics.bsky.social
##Bioinformatics #SpatialTranscriptomics #Xenium #Visium #PostDoc #Hiring #MolecularBiology #Genomics #scRNAseq #Neuroscience 🧬💻🧠
shttps://careers.duke.edu/job/Durham-POSTDOCTORAL-ASSOCIATE-NC-27710/1243119300/
##Bioinformatics #SpatialTranscriptomics #Xenium #Visium #PostDoc #Hiring #MolecularBiology #Genomics #scRNAseq #Neuroscience 🧬💻🧠
#DiabeticKidneyDisease #CaseReport
#SpatialTranscriptomics #Visium @10xGenomics
50-μm section multiplex IF
TEM▶️⏫Periglomerular Capillaries + de novo vascular anastomosis crossing Bowmen capsule
#KPMProject #CJASN 2024
journals.lww.com/cjasn/abstra...
#DiabeticKidneyDisease #CaseReport
#SpatialTranscriptomics #Visium @10xGenomics
50-μm section multiplex IF
TEM▶️⏫Periglomerular Capillaries + de novo vascular anastomosis crossing Bowmen capsule
#KPMProject #CJASN 2024
journals.lww.com/cjasn/abstra...
- any tissue type (eye, kidney, pancreas, brain,...)
- any disease (cancer, fibrosis, diabetes,...)
- any species (human, mouse, rhesus macaque, ...)
It can be integrated with any spatial omic technique (CODEX, Visium, IF, IHC,..)
www.nature.com/articles/s41...
- any tissue type (eye, kidney, pancreas, brain,...)
- any disease (cancer, fibrosis, diabetes,...)
- any species (human, mouse, rhesus macaque, ...)
It can be integrated with any spatial omic technique (CODEX, Visium, IF, IHC,..)
www.nature.com/articles/s41...
STAnalyzer
Human-in-the-Loop Multi-agent (Orchestrator/Service Planner/Data Interpretation/Knowledge Integration) framework
www.sdu-idea.cn/STAnalyzer/
Work on Visium Xenium
From raw counts to hypothesis generation
bioRxiv 2026
www.biorxiv.org/content/10.6...
STAnalyzer
Human-in-the-Loop Multi-agent (Orchestrator/Service Planner/Data Interpretation/Knowledge Integration) framework
www.sdu-idea.cn/STAnalyzer/
Work on Visium Xenium
From raw counts to hypothesis generation
bioRxiv 2026
www.biorxiv.org/content/10.6...
THBS1/Thrombospodin-1 KO in Myeloid cell, not #EndothelialCell, ⬇️ #AorticAneurysm but⬆️ #AorticRupture in 🐭AAA AngII+Apoe KO
Likely compromised TGFb-ECM-stabilizing SMCs & fibroblasts
bioRxiv 2024
www.biorxiv.org/content/10.1...
THBS1/Thrombospodin-1 KO in Myeloid cell, not #EndothelialCell, ⬇️ #AorticAneurysm but⬆️ #AorticRupture in 🐭AAA AngII+Apoe KO
Likely compromised TGFb-ECM-stabilizing SMCs & fibroblasts
bioRxiv 2024
www.biorxiv.org/content/10.1...
Human Kidney N>20
Healthy #AKI #CKD
Crazy loads of data to explore🤠
Does vascular niche affect the regenerative vs degenerative transition of adaptive epithelial states?🤓
#Nature 2024
www.nature.com/articles/s41...
Human Kidney N>20
Healthy #AKI #CKD
Crazy loads of data to explore🤠
Does vascular niche affect the regenerative vs degenerative transition of adaptive epithelial states?🤓
#Nature 2024
www.nature.com/articles/s41...
Glomerular microvascular cell landscape shift in #DiabeticKidneyDisease
MEF2A/MEF2C/TRPS1 in Glomerular #EndothelialCell phenotypic plasticity & EC-to-Mural cell/Podocyte communications
SEMA6A-PLXNA2
bioRxiv 2024
www.biorxiv.org/content/10.1...
Glomerular microvascular cell landscape shift in #DiabeticKidneyDisease
MEF2A/MEF2C/TRPS1 in Glomerular #EndothelialCell phenotypic plasticity & EC-to-Mural cell/Podocyte communications
SEMA6A-PLXNA2
bioRxiv 2024
www.biorxiv.org/content/10.1...
Mild TBI results in extensive gene dysregulation!
#cellreports #neurotrauma #hippocampus #postdoc
@markcembrowski.bsky.social @briannabristow.bsky.social
Mild TBI results in extensive gene dysregulation!
#cellreports #neurotrauma #hippocampus #postdoc
@markcembrowski.bsky.social @briannabristow.bsky.social