LMAO Dream On, Brewers signing off with a Rockin' Apple WAPL / LAZER 103 staple, classic Wisconsin
September 27, 2026 at 9:45 PM
LMAO Dream On, Brewers signing off with a Rockin' Apple WAPL / LAZER 103 staple, classic Wisconsin
OFFICIAL: Leeds have won promotion to the Premier League after securing a top-two finish in the Championship.
Huge congratulations to Daniel Farke, the coaching staff and the players. 👏
lufcdata.com | #LUFC
Huge congratulations to Daniel Farke, the coaching staff and the players. 👏
lufcdata.com | #LUFC
April 21, 2025 at 8:19 PM
Glad to see this out and happy that we could contribute to interesting study in which a surprising role for WAPL and WAPL/CTCF depletion in 2CLC conversion has been uncovered: link.springer.com/article/10.1...
Congrats to Sergio and team!
Congrats to Sergio and team!
Alterations in chromatin organization promote totipotent-like features in a DPPA2/DUX-dependent manner - The EMBO Journal
2-cell like cells (2CLC) are a transiently cycling population of cells with totipotent-associated features. Although CTCF depletion induces 2CLC conversion in mouse ESC, whether this reprogramming is ...
link.springer.com
August 19, 2026 at 10:10 AM
Glad to see this out and happy that we could contribute to interesting study in which a surprising role for WAPL and WAPL/CTCF depletion in 2CLC conversion has been uncovered: link.springer.com/article/10.1...
Congrats to Sergio and team!
Congrats to Sergio and team!
(1/n) Excited to present the latest work from the de Wit lab, where we identify and characterise loop extrusion-mediated fountains in mammalian genomes using acute depletion of 3D genome regulators: doi.org/10.1093/nar/.... A Bluetorial🧵:
Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers
Abstract. Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-effec
doi.org
July 1, 2025 at 6:34 AM
(1/n) Excited to present the latest work from the de Wit lab, where we identify and characterise loop extrusion-mediated fountains in mammalian genomes using acute depletion of 3D genome regulators: doi.org/10.1093/nar/.... A Bluetorial🧵:
youtu.be/LSYEb98ay74
UAZの 1/12RCが出るの？
UAZの 1/12RCが出るの？
【WAPL JAPAN】無骨で、愛嬌がある。UAZ-452（C104 RTR）｜1/12 RCカー
YouTube video by RAYWOOD_official
youtu.be
September 15, 2026 at 9:51 AM
youtu.be/LSYEb98ay74
UAZの 1/12RCが出るの？
UAZの 1/12RCが出るの？
#BestSongHeardToday #MusicChallenge #MusicSky
I've been digging fairly deep into Backyard Tire Fire's catalogue of late. "Hell and Back"
www.youtube.com/watch?v=wAPl...
I've been digging fairly deep into Backyard Tire Fire's catalogue of late. "Hell and Back"
www.youtube.com/watch?v=wAPl...
September 17, 2026 at 3:37 AM
#BestSongHeardToday #MusicChallenge #MusicSky
I've been digging fairly deep into Backyard Tire Fire's catalogue of late. "Hell and Back"
www.youtube.com/watch?v=wAPl...
I've been digging fairly deep into Backyard Tire Fire's catalogue of late. "Hell and Back"
www.youtube.com/watch?v=wAPl...
Just saw this. The beginning of a new old game!
Brilliantly cool!
#8bit #mos6502 #commodorepet
www.youtube.com/watch?v=WAPl...
Brilliantly cool!
#8bit #mos6502 #commodorepet
www.youtube.com/watch?v=WAPl...
Castle Wolfenstein 3D .. for the Commodore PET.
YouTube video by jimo9757
www.youtube.com
July 11, 2024 at 3:58 PM
Just saw this. The beginning of a new old game!
Brilliantly cool!
#8bit #mos6502 #commodorepet
www.youtube.com/watch?v=WAPl...
Brilliantly cool!
#8bit #mos6502 #commodorepet
www.youtube.com/watch?v=WAPl...
◉ Chelsea
Os primeiros 50 jogos de Kai Havertz pelo Chelsea x Nicolas Jackson os primeiros 50 jogos pelo Chelsea. | via Chelsea Blog 1
#PremierLeague
#CFC
#WAPL
Os primeiros 50 jogos de Kai Havertz pelo Chelsea x Nicolas Jackson os primeiros 50 jogos pelo Chelsea. | via Chelsea Blog 1
#PremierLeague
#CFC
#WAPL
September 24, 2024 at 7:44 PM
◉ Chelsea
Os primeiros 50 jogos de Kai Havertz pelo Chelsea x Nicolas Jackson os primeiros 50 jogos pelo Chelsea. | via Chelsea Blog 1
#PremierLeague
#CFC
#WAPL
Os primeiros 50 jogos de Kai Havertz pelo Chelsea x Nicolas Jackson os primeiros 50 jogos pelo Chelsea. | via Chelsea Blog 1
#PremierLeague
#CFC
#WAPL
First time I heard "Fast Car" by Tracy Chapman was on my way back up to college in Appleton, Wisconsin, after Christmas break. It was on WAPL ("The Rockin' Apple," natch) and I made my dad pull into a gas station so I could call in. "What is THAT?" I asked. "I KNOW!" the DJ said.
September 1, 2026 at 1:36 PM
First time I heard "Fast Car" by Tracy Chapman was on my way back up to college in Appleton, Wisconsin, after Christmas break. It was on WAPL ("The Rockin' Apple," natch) and I made my dad pull into a gas station so I could call in. "What is THAT?" I asked. "I KNOW!" the DJ said.
Rayalaseema Xen Stars Women were crowned Women's Andhra Premier League (WAPL) 2026 champions after defeating Godavari Golden Eagles Women by six wickets in the final at the ACA International Stadium in Mangalagiri.
September 29, 2026 at 6:49 AM
Rayalaseema Xen Stars Women were crowned Women's Andhra Premier League (WAPL) 2026 champions after defeating Godavari Golden Eagles Women by six wickets in the final at the ACA International Stadium in Mangalagiri.
8/ We first explored a known but puzzling genetic interaction: inactivating WAPL (the cohesin unloader) increases cohesin lifetime tremendously and compacts chromosomes.
Co-depleting NIPBL alongside WAPL fixes Hi-C close to normal, but without restoring normal cohesin dynamics. How? 🤷
Co-depleting NIPBL alongside WAPL fixes Hi-C close to normal, but without restoring normal cohesin dynamics. How? 🤷
August 16, 2025 at 3:03 AM
8/ We first explored a known but puzzling genetic interaction: inactivating WAPL (the cohesin unloader) increases cohesin lifetime tremendously and compacts chromosomes.
Co-depleting NIPBL alongside WAPL fixes Hi-C close to normal, but without restoring normal cohesin dynamics. How? 🤷
Co-depleting NIPBL alongside WAPL fixes Hi-C close to normal, but without restoring normal cohesin dynamics. How? 🤷
September 10, 2020
Marshmello & Demi Lovato released "OK Not To Be OK".
www.youtube.com/watch?v=wAPl...
Marshmello & Demi Lovato released "OK Not To Be OK".
www.youtube.com/watch?v=wAPl...
Marshmello & Demi Lovato - OK Not To Be OK (Official Music Video)
YouTube video by Marshmello
www.youtube.com
September 10, 2025 at 12:40 PM
September 10, 2020
Marshmello & Demi Lovato released "OK Not To Be OK".
www.youtube.com/watch?v=wAPl...
Marshmello & Demi Lovato released "OK Not To Be OK".
www.youtube.com/watch?v=wAPl...
Post an album that was important to you when you were 11.
Truth: I got into this later than age 11. They didn’t play this on WIXX or WAPL
Truth: I got into this later than age 11. They didn’t play this on WIXX or WAPL
February 18, 2026 at 2:17 AM
Post an album that was important to you when you were 11.
Truth: I got into this later than age 11. They didn’t play this on WIXX or WAPL
Truth: I got into this later than age 11. They didn’t play this on WIXX or WAPL
17/ ✔️Satisfyingly, by iFRAP @lucagiorgetti.bsky.social indeed saw smaller increase in lifetime after PDS5 vs. WAPL depletion.
August 16, 2025 at 3:03 AM
17/ ✔️Satisfyingly, by iFRAP @lucagiorgetti.bsky.social indeed saw smaller increase in lifetime after PDS5 vs. WAPL depletion.
Civic Media Puts More ‘Local’ Back into Wisconsin Radio. Great article from my friend Len Nelson, formerly of WAPL Radio in Appleton. #WisconsinNews
shepherdexpress.com/news/feature...
shepherdexpress.com/news/feature...
Civic Media Puts More ‘Local’ Back into Wisconsin Radio
The statewide network is countering the prevalence of misinformation and disinformation in the corporate media ecosystem.
shepherdexpress.com
December 6, 2024 at 6:26 PM
Civic Media Puts More ‘Local’ Back into Wisconsin Radio. Great article from my friend Len Nelson, formerly of WAPL Radio in Appleton. #WisconsinNews
shepherdexpress.com/news/feature...
shepherdexpress.com/news/feature...
November 22, 2024 at 8:18 PM
11/ This explains how WAPL+NIPBL double mutants have near normal genome folding patterns (cohesin processivity is preserved), despite cohesin dynamics remaining abnormal
August 16, 2025 at 3:03 AM
11/ This explains how WAPL+NIPBL double mutants have near normal genome folding patterns (cohesin processivity is preserved), despite cohesin dynamics remaining abnormal
◉ Southampton
Desempenho do clube na Premier League nesta temporada:
• 4 partidas
• 4 derrotas
• 1 gol marcado
• 8 gols sofridos
#PremierLeague
#SaintsFC
#WAPL
Desempenho do clube na Premier League nesta temporada:
• 4 partidas
• 4 derrotas
• 1 gol marcado
• 8 gols sofridos
#PremierLeague
#SaintsFC
#WAPL
September 14, 2024 at 11:07 PM
◉ Southampton
Desempenho do clube na Premier League nesta temporada:
• 4 partidas
• 4 derrotas
• 1 gol marcado
• 8 gols sofridos
#PremierLeague
#SaintsFC
#WAPL
Desempenho do clube na Premier League nesta temporada:
• 4 partidas
• 4 derrotas
• 1 gol marcado
• 8 gols sofridos
#PremierLeague
#SaintsFC
#WAPL
Loop extrusion is thus important for distal activation, as seen before by us and other labs. On the other end of the spectrum, WAPL unloads cohesin from chromatin. What happens when we degrade WAPL and activate? 4/
May 11, 2026 at 3:30 PM
Loop extrusion is thus important for distal activation, as seen before by us and other labs. On the other end of the spectrum, WAPL unloads cohesin from chromatin. What happens when we degrade WAPL and activate? 4/
September 14, 2024 at 10:24 PM
September 24, 2024 at 3:25 PM
15/ Experimentally, compartmentalization is much more suppressed after PDS5 vs. WAPL depletion 💡
August 16, 2025 at 3:03 AM
15/ Experimentally, compartmentalization is much more suppressed after PDS5 vs. WAPL depletion 💡