RESEARCH PAPER: DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development
By Mason et al. and Frank Conlon
➡️ https://genesdev.cshlp.org/content/40/13-14/1029.abstract

#cardiacdevelopment #sexdifferences #Xlinked #translation

Male-to-male transmission excludes X-linked inheritance. An affected father will pass the mutant X to all daughters (carriers) but not to sons. #USMLE #XLinked #Genetics

Confirmed a 57bp deletion running through an XLinked family with manifesting carriers

Let's see 23 and Me pull that one off

🆕 ADVANCE ONLINE 🆕

RESEARCH PAPER: DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development
By Mason et al. and and Frank Conlon
➡️ https://ow.ly/y6gw50Z4UqV

#cardiacdevelopment #sexdifferences #Xlinked #translation

𝐋𝐢𝐟𝐞 𝐰𝐢𝐭𝐡 𝐭𝐰𝐨 𝐗 𝐜𝐡𝐫𝐨𝐦𝐨𝐬𝐨𝐦𝐞𝐬: agneseloda.bsky.social at bioRN Lounge:

💡 Women are incredibly variable thanks to inactivation of X chromosome
💡 Xist RNA could regulate dosage of Xlinked genes throughout life
💡 Natural fluctuations in Xist RNA could influence protein dosage in women.

bit.ly/43pSDaI

just realized I skipped a bunch of context but yeah, the OTF font I wanted to use ended up being an SVG font with no fallbacks and all the SVGs were just xlinked PNGs lol

also the Fitbit SDK doesn't support the Versa 4 over a year after release and getting around that was a pain too

reidentification: even anonymized data can be xlinked w leaked datasets to reidentify individuals (age x location x dx) #medinfo2025 #aigovernance