Delighted to announce the publication of our work in @nature.com, in collaboration with @nfchilton.bsky.social's group, on a dysprosium compound with magnetic memory at 100 Kelvin. Congrats to all authors inc. @gemmagransbury.bsky.social, @jeffjefftyjeff.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Soft magnetic hysteresis in a dysprosium amide–alkene complex up to 100 kelvin - Nature
A dysprosium amide–alkene complex shows soft magnetic hysteresis loops up to 100 kelvin, arising from the high charge density of the amide ligands and the structural role of the pendant alkene.
www.nature.com
June 25, 2025 at 5:56 PM
Delighted to announce the publication of our work in @nature.com, in collaboration with @nfchilton.bsky.social's group, on a dysprosium compound with magnetic memory at 100 Kelvin. Congrats to all authors inc. @gemmagransbury.bsky.social, @jeffjefftyjeff.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Oh, so you’re a chemist then…
Name 20 amide forming reactions
You have 30 seconds…
Go!
#ChemSky
(Disclaimer: related to a lab conversation today - how many different amide reactions do we use regularly…answer = many)
Name 20 amide forming reactions
You have 30 seconds…
Go!
#ChemSky
(Disclaimer: related to a lab conversation today - how many different amide reactions do we use regularly…answer = many)
September 23, 2026 at 2:35 AM
Oh, so you’re a chemist then…
Name 20 amide forming reactions
You have 30 seconds…
Go!
#ChemSky
(Disclaimer: related to a lab conversation today - how many different amide reactions do we use regularly…answer = many)
Name 20 amide forming reactions
You have 30 seconds…
Go!
#ChemSky
(Disclaimer: related to a lab conversation today - how many different amide reactions do we use regularly…answer = many)
COUPLE TWO TREES
September 24, 2026 at 12:46 AM
COUPLE TWO TREES
N-(2,4,6-trinitrophenyl)-ethanoic acid amide
C₈H₆N₄O₇
C₈H₆N₄O₇
April 28, 2026 at 7:35 PM
N-(2,4,6-trinitrophenyl)-ethanoic acid amide
C₈H₆N₄O₇
C₈H₆N₄O₇
E. coli engineered with a new-to-nature amino acid polymerization pathway produces a bioplastic called poly(ester amide) www.nature.com/articles/s41... #NBTHighlight
Biosynthesis of poly(ester amide)s in engineered Escherichia coli - Nature Chemical Biology
Biobased polymers provide a sustainable alternative to petroleum-based plastics. In this study, the authors engineered Escherichia coli to biosynthesize poly(ester amide)s with customizable amino acid...
www.nature.com
March 20, 2025 at 8:00 AM
E. coli engineered with a new-to-nature amino acid polymerization pathway produces a bioplastic called poly(ester amide) www.nature.com/articles/s41... #NBTHighlight
🚨 Our new paper is out! 🙌
Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4
Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4
A modular genetic code expansion approach to site-specific lysine acylations
A modular strategy combining genetic code expansion with a selective amide bond-forming
reaction enables the site-specific installation of lysine acylations on folded proteins.
Acylboronates react sel...
www.cell.com
March 11, 2026 at 4:51 PM
🚨 Our new paper is out! 🙌
Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4
Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4
DCM has been here the whole time...but will its newfound amide-coupling abilities be a game changer?
Yet another new thing from me @cenmag.bsky.social :
cen.acs.org/synthesis/re...
Yet another new thing from me @cenmag.bsky.social :
cen.acs.org/synthesis/re...
Dichloromethane was an amide coupling reagent this whole time
Chemists make simple amides using only inexpensive lab chemicals
cen.acs.org
July 17, 2026 at 8:07 PM
DCM has been here the whole time...but will its newfound amide-coupling abilities be a game changer?
Yet another new thing from me @cenmag.bsky.social :
cen.acs.org/synthesis/re...
Yet another new thing from me @cenmag.bsky.social :
cen.acs.org/synthesis/re...
In a chemistry version of whipping up a delicious dinner from pantry staples, researchers in Korea have found a recipe for forging amide bonds using inexpensive chemicals stocked in nearly any organic laboratory: dichloromethane (DCM) and a basic salt.
#chemsky 🧪
#chemsky 🧪
Dichloromethane was an amide coupling reagent this whole time
Chemists make simple amides using only inexpensive lab chemicals
cen.acs.org
July 20, 2026 at 6:23 PM
In a chemistry version of whipping up a delicious dinner from pantry staples, researchers in Korea have found a recipe for forging amide bonds using inexpensive chemicals stocked in nearly any organic laboratory: dichloromethane (DCM) and a basic salt.
#chemsky 🧪
#chemsky 🧪
Adams suspended from BBC radio show amide bullying claims from junior staff. Not for the 1st time either. What's going on at the BBC?. Time they cleaned house.
November 2, 2025 at 2:58 PM
Adams suspended from BBC radio show amide bullying claims from junior staff. Not for the 1st time either. What's going on at the BBC?. Time they cleaned house.
Looks like DMAP in an amide formation
February 8, 2025 at 9:39 PM
Looks like DMAP in an amide formation
Thanks Na for baking delicious #ChristmasCookies to celebrate her latest paper #organometallics @acspublications.bsky.social on #cobalt amide chemistry @unibern.bsky.social
December 16, 2024 at 9:26 PM
Thanks Na for baking delicious #ChristmasCookies to celebrate her latest paper #organometallics @acspublications.bsky.social on #cobalt amide chemistry @unibern.bsky.social
Scientists have discovered that erucamide, a plant-produced fatty acid amide, disrupts the function of the bacterial injectosome—a syringe-like nanomachine that some pathogenic bacteria use to help them infect their host. cen.acs.org/biological-c... #chemsky🧪 #biosky
March 13, 2025 at 2:18 PM
Scientists have discovered that erucamide, a plant-produced fatty acid amide, disrupts the function of the bacterial injectosome—a syringe-like nanomachine that some pathogenic bacteria use to help them infect their host. cen.acs.org/biological-c... #chemsky🧪 #biosky
#ChemSky Post your favorite amide forming reactions #ChemistsWhoCookAmides
The "every way to cook a [insert versatile ingredient]" from Bon appétit but it's chemistry. First one in the series is of course "every way to make an amide bond": DCC, HOBt, Schmidt, Schotten-Baumann, Beckmann, Ritter... add your fave!
March 13, 2025 at 10:29 PM
#ChemSky Post your favorite amide forming reactions #ChemistsWhoCookAmides
Jek leads our latest preprint in @chemrxiv.bsky.social with the @nfchilton.bsky.social group on a mixed axial dysprosium amide-cyclopentadienyl single-molecule magnet (SMMs). We find similar high-temperature soft hysteretic properties to dysprosium bis(amide) SMMs.
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Magnetic hysteresis up to 73 K in a dysprosium cyclopentadienyl-amide single-molecule magnet
Single-molecule magnets (SMMs) based on dysprosocenium cations, [Dy(CpR)2]+ (CpR = substituted cyclopentadienyl), have set record effective energy barriers to magnetic reversal (Ueff) and temperatures...
chemrxiv.org
June 26, 2025 at 6:13 PM
Jek leads our latest preprint in @chemrxiv.bsky.social with the @nfchilton.bsky.social group on a mixed axial dysprosium amide-cyclopentadienyl single-molecule magnet (SMMs). We find similar high-temperature soft hysteretic properties to dysprosium bis(amide) SMMs.
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Sam Groom tells us about RF-amide receptor agonists on circuitry in different areas of the brain #NeuroendoCelebrate2026
September 2, 2026 at 2:33 PM
Sam Groom tells us about RF-amide receptor agonists on circuitry in different areas of the brain #NeuroendoCelebrate2026
📰 How a century-old solvent can enable efficient amide synthesis
Peptide bonds, a class of amide bonds, link amino acids to form proteins.
Source: Phys.org | Read story
💬 Key global update — what is your view on this?
#NewsBluesky #Bonds #Amide
Peptide bonds, a class of amide bonds, link amino acids to form proteins.
Source: Phys.org | Read story
💬 Key global update — what is your view on this?
#NewsBluesky #Bonds #Amide
How a century-old solvent can enable efficient amide synthesis
Peptide bonds, a class of amide bonds, link amino acids to form proteins.
phys.org
September 25, 2026 at 8:01 PM
📰 How a century-old solvent can enable efficient amide synthesis
Peptide bonds, a class of amide bonds, link amino acids to form proteins.
Source: Phys.org | Read story
💬 Key global update — what is your view on this?
#NewsBluesky #Bonds #Amide
Peptide bonds, a class of amide bonds, link amino acids to form proteins.
Source: Phys.org | Read story
💬 Key global update — what is your view on this?
#NewsBluesky #Bonds #Amide
Päev 1107. Drooni-, raketi- ja liugpommirünnakud. Tiblad kasutavad amide abi kinnikeersmist max. Krõvõi Rihs lasti rakett hotelli, 2 hukkunut, 31 vigastatut. Tiblade droonid sihtisid Odesa juures Privdenne sadamat, mitu tabamust. Sumõs 1 hukkunu. Donetskis liugpommid elumajadesse.
March 6, 2025 at 6:26 AM
Päev 1107. Drooni-, raketi- ja liugpommirünnakud. Tiblad kasutavad amide abi kinnikeersmist max. Krõvõi Rihs lasti rakett hotelli, 2 hukkunut, 31 vigastatut. Tiblade droonid sihtisid Odesa juures Privdenne sadamat, mitu tabamust. Sumõs 1 hukkunu. Donetskis liugpommid elumajadesse.
Super cool paper in @nature.com showing that amide-modified C-termini on damaged proteins act as degrons, recognised by a cognate F-box protein that triggers their clearance by the ubiquitin proteasome system!
🎉Super excited to share our story on how the substrate receptor FBXO31 functions as a quality control factor by recognizing amides. This has been an amazing collaboration between Bode lab and @jcornlab.bsky.social. Special shutout goes to @matthiasmuhar.bsky.social www.nature.com/articles/s41...
C-terminal amides mark proteins for degradation via SCF–FBXO31 - Nature
SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.
www.nature.com
January 29, 2025 at 7:59 PM
Super cool paper in @nature.com showing that amide-modified C-termini on damaged proteins act as degrons, recognised by a cognate F-box protein that triggers their clearance by the ubiquitin proteasome system!
Factors to Consider for Synthesis in 1536-Well Plates─An Amide Coupling Case Study for PROTAC Synthesis
Factors to Consider for Synthesis in 1536-Well Plates─An Amide Coupling Case Study for PROTAC Synthesis
Ultra high-throughput chemistry carried out in 1536-well plates is increasingly utilized for reaction optimization protocols and direct-to-biology (D2B) platforms, where nanomolar quantities of the fi...
pubs.acs.org
February 24, 2025 at 10:56 AM
Factors to Consider for Synthesis in 1536-Well Plates─An Amide Coupling Case Study for PROTAC Synthesis
Congrats to @pact-lab.bsky.social postdoc @ryanntansey.bsky.social on her recent paper looking at the impact of elevated anandamide via FAAH inhibition on brain function in patients with PTSD
What does it do?
Well....not much 😬
www.nature.com/articles/s41...
What does it do?
Well....not much 😬
www.nature.com/articles/s41...
Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial - Translational Psychiatry
Translational Psychiatry - Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial
www.nature.com
February 12, 2026 at 7:24 PM
Congrats to @pact-lab.bsky.social postdoc @ryanntansey.bsky.social on her recent paper looking at the impact of elevated anandamide via FAAH inhibition on brain function in patients with PTSD
What does it do?
Well....not much 😬
www.nature.com/articles/s41...
What does it do?
Well....not much 😬
www.nature.com/articles/s41...
Amide Derivates from the Phytochemical Cinnamic Acid Shows Hope Against Dengue Virus
www.thailandmedical.news/news/amide-d...
www.thailandmedical.news/news/amide-d...
Amide Derivates from the Phytochemical Cinnamic Acid Shows Hope Against Dengue Virus - Thailand Medical News
www.thailandmedical.news
July 17, 2025 at 3:44 AM
Amide Derivates from the Phytochemical Cinnamic Acid Shows Hope Against Dengue Virus
www.thailandmedical.news/news/amide-d...
www.thailandmedical.news/news/amide-d...
Its a long weekend here in Canada, which seems appropriate to mourn our recent @npp-journal.bsky.social paper, in which we find that FAAH inhibition does NOT improve symptoms in PTSD🙁
A heroic effort w/ @cannabrain.bsky.social @connorhaggarty.bsky.social @ryanntansey.bsky.social & many more 🧵⬇️
A heroic effort w/ @cannabrain.bsky.social @connorhaggarty.bsky.social @ryanntansey.bsky.social & many more 🧵⬇️
The efficacy of elevating anandamide via inhibition of fatty acid amide hydrolase (FAAH) combined with internet-delivered cognitive behavioral therapy in the treatment of post-traumatic stress disorde...
Neuropsychopharmacology - The efficacy of elevating anandamide via inhibition of fatty acid amide hydrolase (FAAH) combined with internet-delivered cognitive behavioral therapy in the treatment of...
www.nature.com
May 17, 2025 at 5:48 PM
Its a long weekend here in Canada, which seems appropriate to mourn our recent @npp-journal.bsky.social paper, in which we find that FAAH inhibition does NOT improve symptoms in PTSD🙁
A heroic effort w/ @cannabrain.bsky.social @connorhaggarty.bsky.social @ryanntansey.bsky.social & many more 🧵⬇️
A heroic effort w/ @cannabrain.bsky.social @connorhaggarty.bsky.social @ryanntansey.bsky.social & many more 🧵⬇️