Researchers found that boosting astrocytes helped remove beta-amyloid plaques and preserve cognitive function in Alzheimer's mouse models. The discovery is promising, but human studies are still needed.
DOI: 10.1038/s41593-025-02115-w
DOI: 10.1038/s41593-025-02115-w
November 1, 2026 at 6:00 PM
Researchers found that boosting astrocytes helped remove beta-amyloid plaques and preserve cognitive function in Alzheimer's mouse models. The discovery is promising, but human studies are still needed.
DOI: 10.1038/s41593-025-02115-w
DOI: 10.1038/s41593-025-02115-w
Post-Doc in cryoEM- JOB ALERT!
Are you experienced in solving proteins structures using cryoEM? Are you interested in amyloid formation? We have a post-doc position available in the group, starting ASAP, with Neil Ranson. See jobs.leeds.ac.uk/FBSMB1323, Deadline 25th November. DO NOT DELAY!!
Are you experienced in solving proteins structures using cryoEM? Are you interested in amyloid formation? We have a post-doc position available in the group, starting ASAP, with Neil Ranson. See jobs.leeds.ac.uk/FBSMB1323, Deadline 25th November. DO NOT DELAY!!
November 4, 2026 at 6:03 PM
Post-Doc in cryoEM- JOB ALERT!
Are you experienced in solving proteins structures using cryoEM? Are you interested in amyloid formation? We have a post-doc position available in the group, starting ASAP, with Neil Ranson. See jobs.leeds.ac.uk/FBSMB1323, Deadline 25th November. DO NOT DELAY!!
Are you experienced in solving proteins structures using cryoEM? Are you interested in amyloid formation? We have a post-doc position available in the group, starting ASAP, with Neil Ranson. See jobs.leeds.ac.uk/FBSMB1323, Deadline 25th November. DO NOT DELAY!!
i didn't have to google "amyloid"
Angry Woman Yelling 'Liar!'
ALT: Angry Woman Yelling 'Liar!'
static.klipy.com
November 5, 2026 at 1:14 PM
i didn't have to google "amyloid"
Imagine getting your fat ass handed to you during the midterm elections but your amyloid plaque-ridden brain is not only stuck on your fucking ballroom, but also this...
November 5, 2026 at 1:09 PM
Imagine getting your fat ass handed to you during the midterm elections but your amyloid plaque-ridden brain is not only stuck on your fucking ballroom, but also this...
New preprint 🧬 A 23-residue piece of medin builds an amyloid fibril entirely on its own.
Medin is the most common localized amyloid in humans — it deposits in the aortic wall in virtually everyone over 60, and sits alongside amyloid-β in Alzheimer's vessels.
Medin is the most common localized amyloid in humans — it deposits in the aortic wall in virtually everyone over 60, and sits alongside amyloid-β in Alzheimer's vessels.
November 1, 2026 at 12:30 PM
New preprint 🧬 A 23-residue piece of medin builds an amyloid fibril entirely on its own.
Medin is the most common localized amyloid in humans — it deposits in the aortic wall in virtually everyone over 60, and sits alongside amyloid-β in Alzheimer's vessels.
Medin is the most common localized amyloid in humans — it deposits in the aortic wall in virtually everyone over 60, and sits alongside amyloid-β in Alzheimer's vessels.
Alzheimer’s pathology mediates arteriolosclerosis and cerebral amyloid angiopathy associations with cognition academic.oup.com/brain/articl...
Alzheimer’s pathology mediates arteriolosclerosis and cerebral amyloid angiopathy associations with cognition
Hayes et al. explored how Alzheimer’s pathology affects the relationship between vascular neuropathology and cognitive scores. Alzheimer’s pathology largel
academic.oup.com
November 3, 2026 at 12:05 PM
Alzheimer’s pathology mediates arteriolosclerosis and cerebral amyloid angiopathy associations with cognition academic.oup.com/brain/articl...
Amyloid PET scans have become the gold standard for detecting brain amyloid plaques, a core feature of Alzheimer’s disease. But can local nuclear medicine physicians and radiologists interpret the scans as well as experts?
November 3, 2026 at 1:55 PM
Amyloid PET scans have become the gold standard for detecting brain amyloid plaques, a core feature of Alzheimer’s disease. But can local nuclear medicine physicians and radiologists interpret the scans as well as experts?
Imipramine binds to amyloid-β and extends the survival of Alzheimer's disease patients https://www.biorxiv.org/content/10.64898/2026.10.28.762584v1
November 3, 2026 at 7:17 PM
Imipramine binds to amyloid-β and extends the survival of Alzheimer's disease patients https://www.biorxiv.org/content/10.64898/2026.10.28.762584v1
Brain mitovesicles undergo stage-specific remodelling during the progression of amyloid-β pathology https://www.biorxiv.org/content/10.64898/2026.10.30.762534v1
November 3, 2026 at 8:16 PM
Brain mitovesicles undergo stage-specific remodelling during the progression of amyloid-β pathology https://www.biorxiv.org/content/10.64898/2026.10.30.762534v1
🧠 A major Cochrane review (April 2026) pooled 17 randomised trials and 20,342 people. Its conclusion: anti-amyloid antibodies make little or no clinically meaningful difference in mild Alzheimer’s. It’s a hard result, so let’s unpack it carefully. 🧵
November 4, 2026 at 5:52 PM
🧠 A major Cochrane review (April 2026) pooled 17 randomised trials and 20,342 people. Its conclusion: anti-amyloid antibodies make little or no clinically meaningful difference in mild Alzheimer’s. It’s a hard result, so let’s unpack it carefully. 🧵
www.biorxiv.org/content/10.6...
@vib-switch-lab.bsky.social @vibneuroleuven.bsky.social @viblifesciences.bsky.social
@vib-switch-lab.bsky.social @vibneuroleuven.bsky.social @viblifesciences.bsky.social
Two polymorphs of an independent amyloid core in medin's C- terminal region.
Medin, a 50-residue fragment of lactadherin (MFG-E8), forms aortic medial amyloid, the most common localized amyloid in humans, and co-deposits with vascular amyloid-β (Aβ) in Alzheimer's disease. In ...
www.biorxiv.org
November 1, 2026 at 12:28 PM
Amyloid PET in Europe | Throwback to the #EANM26 EU Affairs Track 🇪🇺
🔗 Find out more about #HTA in nuclear medicine: https://eanm.org/wp-content/uploads/2025/12/EU_Policy_Symposium2_Report.pdf
🔗 Find out more about #HTA in nuclear medicine: https://eanm.org/wp-content/uploads/2025/12/EU_Policy_Symposium2_Report.pdf
November 6, 2026 at 9:25 AM
Amyloid PET in Europe | Throwback to the #EANM26 EU Affairs Track 🇪🇺
🔗 Find out more about #HTA in nuclear medicine: https://eanm.org/wp-content/uploads/2025/12/EU_Policy_Symposium2_Report.pdf
🔗 Find out more about #HTA in nuclear medicine: https://eanm.org/wp-content/uploads/2025/12/EU_Policy_Symposium2_Report.pdf
Arginine reduced amyloid-beta plaques and neuroinflammation in transgenic animal models, though human trials remain years away.
https://news.gmj.ge/briefs/preclinical-data-arginine-reduced-amyloid-beta-plaques-in-alzheimers-disease-models/
https://news.gmj.ge/briefs/preclinical-data-arginine-reduced-amyloid-beta-plaques-in-alzheimers-disease-models/
Preclinical Data: Arginine Reduced Amyloid-Beta Plaques in Alzheimer’s Disease Models
Arginine reduced amyloid-beta plaques and neuroinflammation in transgenic animal models, though human trials remain years away.
news.gmj.ge
November 5, 2026 at 7:27 AM
Arginine reduced amyloid-beta plaques and neuroinflammation in transgenic animal models, though human trials remain years away.
https://news.gmj.ge/briefs/preclinical-data-arginine-reduced-amyloid-beta-plaques-in-alzheimers-disease-models/
https://news.gmj.ge/briefs/preclinical-data-arginine-reduced-amyloid-beta-plaques-in-alzheimers-disease-models/
Open Access UCL Research: Dementia with Lewy bodies and amyloid pathology: Eligible for anti-amyloid treatment or not? discovery.ucl.ac.uk/id/eprint/10...
Dementia with Lewy bodies and amyloid pathology: Eligible for anti-amyloid treatment or not?
-
UCL Discovery
UCL Discovery is UCL's open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
discovery.ucl.ac.uk
November 4, 2026 at 7:28 PM
Open Access UCL Research: Dementia with Lewy bodies and amyloid pathology: Eligible for anti-amyloid treatment or not? discovery.ucl.ac.uk/id/eprint/10...
What does the Lumipulse pTau-217/Beta Amyloid 42 Ratio test look at?
It combines information from:
p-tau217
and
beta-amyloid 42
The result can help identify amyloid pathology associated with Alzheimer’s disease in appropriate clinical settings.
#MemoryProtection #AlzheimersDisease #CognitiveTesting
It combines information from:
p-tau217
and
beta-amyloid 42
The result can help identify amyloid pathology associated with Alzheimer’s disease in appropriate clinical settings.
#MemoryProtection #AlzheimersDisease #CognitiveTesting
November 4, 2026 at 2:04 PM
What does the Lumipulse pTau-217/Beta Amyloid 42 Ratio test look at?
It combines information from:
p-tau217
and
beta-amyloid 42
The result can help identify amyloid pathology associated with Alzheimer’s disease in appropriate clinical settings.
#MemoryProtection #AlzheimersDisease #CognitiveTesting
It combines information from:
p-tau217
and
beta-amyloid 42
The result can help identify amyloid pathology associated with Alzheimer’s disease in appropriate clinical settings.
#MemoryProtection #AlzheimersDisease #CognitiveTesting
We need a serious chat about biomarkers, the corporatisation of brain health, and the contextualisation of disease modifying drugs and where this places our current understanding of tau and amyloid. In the meantime we must sort out the abuse of unpaid carers.
November 6, 2026 at 7:21 AM
We need a serious chat about biomarkers, the corporatisation of brain health, and the contextualisation of disease modifying drugs and where this places our current understanding of tau and amyloid. In the meantime we must sort out the abuse of unpaid carers.
Read full article:
psyll.com/articles/sci...
psyll.com/articles/sci...
Why Alzheimer's drugs may miss the clinical mark | Psyll
A major review of 20,000 patients suggests amyloid-clearing Alzheimer's drugs may not provide meaningful clinical benefits while posing significant brain risks.
psyll.com
November 4, 2026 at 5:53 PM
Read full article:
psyll.com/articles/sci...
psyll.com/articles/sci...
Amyloid/RNA Condensates with Germ Granule Characteristics Are Present in Rat Epididymal Spermatozoa and Exhibit Prion-Like Propagation Activity https://www.biorxiv.org/content/10.64898/2026.10.30.763233v1
November 3, 2026 at 9:31 PM
Amyloid/RNA Condensates with Germ Granule Characteristics Are Present in Rat Epididymal Spermatozoa and Exhibit Prion-Like Propagation Activity https://www.biorxiv.org/content/10.64898/2026.10.30.763233v1
My latest review on #amyloid #PET & blood #biomarkers for #Alzheimer’s provides clinically oriented algorithm for integrating plasma p-tau217, amyloid PET, #tau, & #MRI for monitoring during anti-amyloid #immunotherapy.
Read here: www.mdpi.com/4171100
@mdpiopenaccess.bsky.social #mdpijdad
Read here: www.mdpi.com/4171100
@mdpiopenaccess.bsky.social #mdpijdad
November 3, 2026 at 5:40 AM
My latest review on #amyloid #PET & blood #biomarkers for #Alzheimer’s provides clinically oriented algorithm for integrating plasma p-tau217, amyloid PET, #tau, & #MRI for monitoring during anti-amyloid #immunotherapy.
Read here: www.mdpi.com/4171100
@mdpiopenaccess.bsky.social #mdpijdad
Read here: www.mdpi.com/4171100
@mdpiopenaccess.bsky.social #mdpijdad
This study examines why many #Alzheimersdisease interventions fail in clinical trials despite promising epidemiological associations and preclinical evidence . The study analyze failed programs across infectious, inflammatory, metabolic, lipid, iron, dietary, hormonal, and amyloid domains .
November 6, 2026 at 12:59 PM
This study examines why many #Alzheimersdisease interventions fail in clinical trials despite promising epidemiological associations and preclinical evidence . The study analyze failed programs across infectious, inflammatory, metabolic, lipid, iron, dietary, hormonal, and amyloid domains .
What are amyloid plaques?
They are deposits involving beta-amyloid protein that can accumulate in the brain and are associated with Alzheimer’s disease.
But amyloid is only one part of the biological picture.
#MemoryProtection #AlzheimersDisease #BrainHealth #CognitiveHealth #CognitiveChanges
They are deposits involving beta-amyloid protein that can accumulate in the brain and are associated with Alzheimer’s disease.
But amyloid is only one part of the biological picture.
#MemoryProtection #AlzheimersDisease #BrainHealth #CognitiveHealth #CognitiveChanges
November 3, 2026 at 2:03 PM
What are amyloid plaques?
They are deposits involving beta-amyloid protein that can accumulate in the brain and are associated with Alzheimer’s disease.
But amyloid is only one part of the biological picture.
#MemoryProtection #AlzheimersDisease #BrainHealth #CognitiveHealth #CognitiveChanges
They are deposits involving beta-amyloid protein that can accumulate in the brain and are associated with Alzheimer’s disease.
But amyloid is only one part of the biological picture.
#MemoryProtection #AlzheimersDisease #BrainHealth #CognitiveHealth #CognitiveChanges
📢 STUDENTSHIP: The Harriet and Joan Neal Graduate Research Scholarship into Amyloid Angiopathy
Find out more and apply: tinyurl.com/2vzb7ajm
Find out more and apply: tinyurl.com/2vzb7ajm
November 6, 2026 at 5:11 PM
📢 STUDENTSHIP: The Harriet and Joan Neal Graduate Research Scholarship into Amyloid Angiopathy
Find out more and apply: tinyurl.com/2vzb7ajm
Find out more and apply: tinyurl.com/2vzb7ajm
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling https://www.biorxiv.org/content/10.64898/2026.10.31.763276v1
November 3, 2026 at 7:47 AM
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling https://www.biorxiv.org/content/10.64898/2026.10.31.763276v1
Researchers from the University of Southern California demonstrated that the treatment restored blood clearance in aged rats, reducing amyloid-beta levels by 50%.
#AmyloidBeta #LiverFunction #Aging
#AmyloidBeta #LiverFunction #Aging
Amyloid-beta protein levels in rat blood dropped by half
Source: ScienceAlert
realfeedapp.com
November 6, 2026 at 3:20 PM
Researchers from the University of Southern California demonstrated that the treatment restored blood clearance in aged rats, reducing amyloid-beta levels by 50%.
#AmyloidBeta #LiverFunction #Aging
#AmyloidBeta #LiverFunction #Aging