Predicting clotting events in 49 of 53 people with Covid!
An immunosensor that rapidly detects 4 different protein biomarkers
science.org/doi/10.1126/...
An immunosensor that rapidly detects 4 different protein biomarkers
science.org/doi/10.1126/...
Rapid prediction of acute thrombosis via nanoengineered immunosensors with unsupervised clustering for multiple circulating biomarkers
A nanoengineered immunosensor uses machine learning to detect multiple biomarkers for rapid prediction of acute thrombosis.
science.org
December 11, 2024 at 7:45 PM
Predicting clotting events in 49 of 53 people with Covid!
An immunosensor that rapidly detects 4 different protein biomarkers
science.org/doi/10.1126/...
An immunosensor that rapidly detects 4 different protein biomarkers
science.org/doi/10.1126/...
This is getting passed around a lot because of the way it's worded but it's important to note that researchers have not shown any such thing - they have shown that mice with similar biomarkers can have those biomarkers reversed. No human testing has occurred and shown recovery of cognition & memory.
GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages.
December 29, 2025 at 12:39 AM
This is getting passed around a lot because of the way it's worded but it's important to note that researchers have not shown any such thing - they have shown that mice with similar biomarkers can have those biomarkers reversed. No human testing has occurred and shown recovery of cognition & memory.
When you look for secreted biomarkers and only find BSA
January 29, 2025 at 4:22 PM
When you look for secreted biomarkers and only find BSA
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
November 4, 2025 at 4:28 PM
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
Now that we can assay thousands of plasma proteins in 1-2 ml of blood, there's discovery and validation of many new cancer biomarkers
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cancer biomarkers discovered using pan-cancer plasma proteomic profiling - Nature Biomedical Engineering
Proteome profiling of plasma samples in human pan-cancer cohorts reveals patterns of biomarkers for diagnosis.
www.nature.com
July 2, 2025 at 4:13 PM
Now that we can assay thousands of plasma proteins in 1-2 ml of blood, there's discovery and validation of many new cancer biomarkers
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Presenting #LongCovid as a disease "without biomarkers" is a way to minimize the disease entity. Making it a "mystery", some "fatigue", "unexplained symptoms". Yet, everyone who reads the scientific literature knows that a rich palette of biomarkers are associated with LC
July 27, 2025 at 5:03 PM
Presenting #LongCovid as a disease "without biomarkers" is a way to minimize the disease entity. Making it a "mystery", some "fatigue", "unexplained symptoms". Yet, everyone who reads the scientific literature knows that a rich palette of biomarkers are associated with LC
Identifying reproducible biomarkers for microbiome association studies requires sample sizes of thousands www.sciencedirect.com/science/arti...
Identifying reproducible biomarkers for microbiome association studies requires thousands of sample sizes
www.sciencedirect.com
July 27, 2025 at 9:10 AM
Identifying reproducible biomarkers for microbiome association studies requires sample sizes of thousands www.sciencedirect.com/science/arti...
Only a subset of patients respond to immunotherapy
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
November 27, 2024 at 2:13 PM
Only a subset of patients respond to immunotherapy
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
p-tau217, the breakthrough blood biomarker for Alzheimer's, picks up risk the earliest and its performance surpasses all other tau biomarkers, across ancestries
www.nature.com/articles/s43...
My review erictopol.substack.com/p/the-breakt...
www.nature.com/articles/s43...
My review erictopol.substack.com/p/the-breakt...
Comprehensive evaluation of plasma tau biomarkers for detecting and monitoring Alzheimer’s disease in a multicenter and multiethnic aging population - Nature Aging
Lan et al. demonstrate the high performance of plasma p-tau217 in detecting and tracking multiple aspects of Alzheimer’s disease pathology, outperforming other plasma tau biomarkers across two Chinese...
www.nature.com
June 23, 2025 at 1:33 PM
p-tau217, the breakthrough blood biomarker for Alzheimer's, picks up risk the earliest and its performance surpasses all other tau biomarkers, across ancestries
www.nature.com/articles/s43...
My review erictopol.substack.com/p/the-breakt...
www.nature.com/articles/s43...
My review erictopol.substack.com/p/the-breakt...
Higher levels of physical activity are linked to lower plasma p-Tau217 (blood biomarker for Alzheimer's disease) and better cognition
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Physical Activity, Alzheimer Plasma Biomarkers, and Cognition
This cross-sectional study examines associations among physical activity, plasma biomarkers, and cognition in a multicenter cohort of patients with and without cognitive impairment.
jamanetwork.com
March 5, 2025 at 4:16 PM
Higher levels of physical activity are linked to lower plasma p-Tau217 (blood biomarker for Alzheimer's disease) and better cognition
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Ultrasensitive test detects biomarkers for specific form of dementia wyss.harvard.edu/news/ultrase...
#FTLD #dementia #biomarkers #science #neuroscience #NeuroSkyence
#FTLD #dementia #biomarkers #science #neuroscience #NeuroSkyence
Ultrasensitive test detects biomarkers for specific form of dementia
By MGB Communications (BOSTON) — Dementia affects over 57 million people worldwide, a number expected to nearly double in the next 20 years. This permanent loss of cognitive abilities affects daily fu...
wyss.harvard.edu
May 11, 2026 at 7:13 PM
Ultrasensitive test detects biomarkers for specific form of dementia wyss.harvard.edu/news/ultrase...
#FTLD #dementia #biomarkers #science #neuroscience #NeuroSkyence
#FTLD #dementia #biomarkers #science #neuroscience #NeuroSkyence
The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
November 22, 2024 at 6:05 PM
The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Inflammation, cell and mitochondria damage biomarkers, and links to cognitive dysfunction in #LongCovid relative to recovered controls
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 9, 2026 at 3:05 PM
Inflammation, cell and mitochondria damage biomarkers, and links to cognitive dysfunction in #LongCovid relative to recovered controls
www.nature.com/articles/s41...
www.nature.com/articles/s41...
p-tau217 and other biomarkers for Alzheimer’s disease also tracked with loss of muscle strength in ~2,000 participants followed 12 years (Figures hand grip and chair-to-stand)
Suggests Brain-to-Muscle bidirectional axis
thelancet.com/journals/lan...
Suggests Brain-to-Muscle bidirectional axis
thelancet.com/journals/lan...
Blood biomarkers of Alzheimer’s disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study
Our findings suggest that blood Alzheimer’s disease-related biomarkers might help
estimate progressive muscle strength decline among older adults, elucidating the influence
of brain pathology and cogn...
thelancet.com
May 22, 2025 at 9:11 PM
p-tau217 and other biomarkers for Alzheimer’s disease also tracked with loss of muscle strength in ~2,000 participants followed 12 years (Figures hand grip and chair-to-stand)
Suggests Brain-to-Muscle bidirectional axis
thelancet.com/journals/lan...
Suggests Brain-to-Muscle bidirectional axis
thelancet.com/journals/lan...
Predicting the risk of developing Alzheimer's disease in the next 10 years with blood biomarkers, such as p-Tau217
www.nature.com/articles/s41... @naturemedicine.bsky.social
www.nature.com/articles/s41... @naturemedicine.bsky.social
March 26, 2025 at 2:27 PM
Predicting the risk of developing Alzheimer's disease in the next 10 years with blood biomarkers, such as p-Tau217
www.nature.com/articles/s41... @naturemedicine.bsky.social
www.nature.com/articles/s41... @naturemedicine.bsky.social
Lecanemab improves amyloid biomarkers but worsens neuronal/synaptic biomarkers. Should we question whether successful amyloid removal improves the biology that matters most? My take on the new study: lnkd.in/p/gfzXAHdj
Important new paper. Continued lecanemab exposure “improves” amyloid-associated biomarkers while some neuronal/synaptic biomarkers move progressively farther from normal.
A team led by Carlos… | Albe...
Important new paper. Continued lecanemab exposure “improves” amyloid-associated biomarkers while some neuronal/synaptic biomarkers move progressively farther from normal.
A team led by Carlos Cruchag...
lnkd.in
October 1, 2026 at 2:16 PM
Lecanemab improves amyloid biomarkers but worsens neuronal/synaptic biomarkers. Should we question whether successful amyloid removal improves the biology that matters most? My take on the new study: lnkd.in/p/gfzXAHdj
Oh wow, I just saw this news.
Australia's TGA has approved a clinical trial of a blood test that can identify biomarkers of Alzheimer's disease two decades before symptoms appear, allowing intervention strategies.
I hope this goes well. This could improve millions of lives globally.
Australia's TGA has approved a clinical trial of a blood test that can identify biomarkers of Alzheimer's disease two decades before symptoms appear, allowing intervention strategies.
I hope this goes well. This could improve millions of lives globally.
newsGP - ‘Milestone’ Alzheimer’s diagnosis blood test gets green light
GPs could one day be offering patients the ‘holy grail’ test, which could detect the disease’s biomarkers up to two decades before symptoms appear.
www1.racgp.org.au
August 1, 2026 at 4:30 AM
Oh wow, I just saw this news.
Australia's TGA has approved a clinical trial of a blood test that can identify biomarkers of Alzheimer's disease two decades before symptoms appear, allowing intervention strategies.
I hope this goes well. This could improve millions of lives globally.
Australia's TGA has approved a clinical trial of a blood test that can identify biomarkers of Alzheimer's disease two decades before symptoms appear, allowing intervention strategies.
I hope this goes well. This could improve millions of lives globally.
It's FTD Awareness Week!
We're proud to be a partner in @predictftd.bsky.social project on frontotemporal dementia (FTD) whose mission is to advance early & accurate diagnosis through innovative biomarkers & AI-driven tools enabling personalised care & support www.predictftd.eu
#spotlightFTD #endFTD
We're proud to be a partner in @predictftd.bsky.social project on frontotemporal dementia (FTD) whose mission is to advance early & accurate diagnosis through innovative biomarkers & AI-driven tools enabling personalised care & support www.predictftd.eu
#spotlightFTD #endFTD
PREDICTFTD | Predictive Liquid Biomarkers
PREDICTFTD - accelerating the validation of predictive liquid biomarkers for frontotemporal dementia diagnosis and subclassification.
www.predictftd.eu
September 29, 2026 at 11:19 AM
It's FTD Awareness Week!
We're proud to be a partner in @predictftd.bsky.social project on frontotemporal dementia (FTD) whose mission is to advance early & accurate diagnosis through innovative biomarkers & AI-driven tools enabling personalised care & support www.predictftd.eu
#spotlightFTD #endFTD
We're proud to be a partner in @predictftd.bsky.social project on frontotemporal dementia (FTD) whose mission is to advance early & accurate diagnosis through innovative biomarkers & AI-driven tools enabling personalised care & support www.predictftd.eu
#spotlightFTD #endFTD
My 36 year old husband has been exercising, gym, taking supplements and watching those stupid longevity videos. He has just paid for blood test for his biological age and biomarkers. They told him he's 35. Help me.
June 23, 2026 at 8:20 AM
My 36 year old husband has been exercising, gym, taking supplements and watching those stupid longevity videos. He has just paid for blood test for his biological age and biomarkers. They told him he's 35. Help me.
Blood biomarkers could detect earliest signs of Alzheimer’s disease – and slow its progression
theconversation.com/blood-biomar...
#Alzheimers #dementia #biomarkers #science #neuroscience #NeuroSkyence
theconversation.com/blood-biomar...
#Alzheimers #dementia #biomarkers #science #neuroscience #NeuroSkyence
Blood biomarkers could detect earliest signs of Alzheimer’s disease – and slow its progression
Studying middle-aged populations is important to understanding what Alzheimer’s disease looks like in the earliest stages, to make preventive measures more effective.
theconversation.com
May 28, 2026 at 7:02 PM
Blood biomarkers could detect earliest signs of Alzheimer’s disease – and slow its progression
theconversation.com/blood-biomar...
#Alzheimers #dementia #biomarkers #science #neuroscience #NeuroSkyence
theconversation.com/blood-biomar...
#Alzheimers #dementia #biomarkers #science #neuroscience #NeuroSkyence
COVID-19 linked to increase in biomarkers for abnormal brain proteins
Imperial News
January 30, 2025
By Samantha Rey, Ryan O’Hare
stillcoviding.ca/en/news/covi...
#research #COVID #CovidIsNotOver
Imperial News
January 30, 2025
By Samantha Rey, Ryan O’Hare
stillcoviding.ca/en/news/covi...
#research #COVID #CovidIsNotOver
COVID-19 linked to increase in biomarkers for abnormal brain proteins
stillcoviding.ca
February 5, 2025 at 9:10 AM
COVID-19 linked to increase in biomarkers for abnormal brain proteins
Imperial News
January 30, 2025
By Samantha Rey, Ryan O’Hare
stillcoviding.ca/en/news/covi...
#research #COVID #CovidIsNotOver
Imperial News
January 30, 2025
By Samantha Rey, Ryan O’Hare
stillcoviding.ca/en/news/covi...
#research #COVID #CovidIsNotOver
Fortunately, we're gettin much better with biomarkers to track the immune response to cancer immunotherapy
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
March 28, 2025 at 4:52 PM
Fortunately, we're gettin much better with biomarkers to track the immune response to cancer immunotherapy
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
I have just read this WIRED article on Long Covid and it keep repeating one claim: "the absence of biomarkers". I'd like to add a fact check: There *are* biomarkers and they are being researched. So for many Long Covid symptoms we can *measure* differences. Example: www.nature.com/articles/s41...
June 2, 2026 at 12:57 PM
I have just read this WIRED article on Long Covid and it keep repeating one claim: "the absence of biomarkers". I'd like to add a fact check: There *are* biomarkers and they are being researched. So for many Long Covid symptoms we can *measure* differences. Example: www.nature.com/articles/s41...
The diffuse inflammation of the brain in symptomatic people with Long Covid by PET scans, with matched controls, and correlation with their blood inflammatory biomarkers
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 21, 2023 at 4:25 PM
The diffuse inflammation of the brain in symptomatic people with Long Covid by PET scans, with matched controls, and correlation with their blood inflammatory biomarkers
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...