Weight-loss jabs may be good for mental health, research shows
Weight-loss jabs may be good for mental health, research shows
Swiss study finds wellbeing and life quality can be improved more than with insulin and other antidiabetic drugs
Weight loss jabs may be good for people’s mental health as well as helping curb their appetite, according to research.
A study by scientists from the University of Bern in Switzerland has found that appetite-suppressing injections also improve mood, wellbeing and quality of life more than insulin and other antidiabetic drugs. Continue reading...
www.theguardian.com
May 10, 2025 at 10:26 PM
Weight-loss jabs may be good for mental health, research shows
Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
July 31, 2025 at 6:52 PM
Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...
I would suggest this has relevance to brain cellular protection in acute infection... Just curious 🧐
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
September 18, 2025 at 8:53 AM
I would suggest this has relevance to brain cellular protection in acute infection... Just curious 🧐
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
🌱 RESEARCH 🌱
Tonoplast-Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana - Hijmans et al.
🔗 doi.org/10.1111/pbi....
#plantscience #synbio 🧪 @leidenscience.bsky.social
Tonoplast-Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana - Hijmans et al.
🔗 doi.org/10.1111/pbi....
#plantscience #synbio 🧪 @leidenscience.bsky.social
September 29, 2026 at 10:47 AM
🌱 RESEARCH 🌱
Tonoplast-Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana - Hijmans et al.
🔗 doi.org/10.1111/pbi....
#plantscience #synbio 🧪 @leidenscience.bsky.social
Tonoplast-Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana - Hijmans et al.
🔗 doi.org/10.1111/pbi....
#plantscience #synbio 🧪 @leidenscience.bsky.social
Weight loss jabs may be good for people’s mental health as well as helping curb their appetite.
A study (link below) has found that appetite-suppressing injections also improve mood, wellbeing & quality of life more than insulin & other antidiabetic drugs.
🧪💉
www.theguardian.com/society/2025...
A study (link below) has found that appetite-suppressing injections also improve mood, wellbeing & quality of life more than insulin & other antidiabetic drugs.
🧪💉
www.theguardian.com/society/2025...
Weight-loss jabs may be good for mental health, research shows
Swiss study finds wellbeing and life quality can be improved more than with insulin and other antidiabetic drugs
www.theguardian.com
May 11, 2025 at 1:37 PM
Weight loss jabs may be good for people’s mental health as well as helping curb their appetite.
A study (link below) has found that appetite-suppressing injections also improve mood, wellbeing & quality of life more than insulin & other antidiabetic drugs.
🧪💉
www.theguardian.com/society/2025...
A study (link below) has found that appetite-suppressing injections also improve mood, wellbeing & quality of life more than insulin & other antidiabetic drugs.
🧪💉
www.theguardian.com/society/2025...
Modern antidiabetic drugs do more than lower sugar, they protect the heart and vessels. This review explains how. #PharmRev 🧪
https://ow.ly/nZLt50XMvsO
https://ow.ly/nZLt50XMvsO
January 2, 2026 at 2:00 PM
Modern antidiabetic drugs do more than lower sugar, they protect the heart and vessels. This review explains how. #PharmRev 🧪
https://ow.ly/nZLt50XMvsO
https://ow.ly/nZLt50XMvsO
This #LongCOVID or #PostCOVID trial is now also listed on ClinicalTrials.
The repurposed drug they’re testing is tirzepatide, an antidiabetic medication.
clinicaltrials.gov/study/NCT071...
The repurposed drug they’re testing is tirzepatide, an antidiabetic medication.
clinicaltrials.gov/study/NCT071...
Contagion Live: 'Remote Long COVID Trial to Evaluate Repurposed Drug Across US'
'The fully remote Long Covid Treatment Trial will enroll 1,000 U.S. participants to evaluate a repurposed drug for Long COVID treatment.'
www.contagionlive.com/view/remote-...
'The fully remote Long Covid Treatment Trial will enroll 1,000 U.S. participants to evaluate a repurposed drug for Long COVID treatment.'
www.contagionlive.com/view/remote-...
Remote Long COVID Trial to Evaluate Repurposed Drug Across US
Julia Moore Vogel, PhD, says the LoCITT study aims to expand access through a fully remote design using CareEvolution’s MyDataHelps platform.
www.contagionlive.com
August 20, 2025 at 2:31 PM
This #LongCOVID or #PostCOVID trial is now also listed on ClinicalTrials.
The repurposed drug they’re testing is tirzepatide, an antidiabetic medication.
clinicaltrials.gov/study/NCT071...
The repurposed drug they’re testing is tirzepatide, an antidiabetic medication.
clinicaltrials.gov/study/NCT071...
Ozempic might be all the rage among people who want to lose weight, but wellness influencers and MAHA acolytes are raging against the antidiabetic medication.
I look into recent statements by RFK Jr and Calley Means to see how their claims hold up to actual data.
www.patreon.com/posts/why-bi...
I look into recent statements by RFK Jr and Calley Means to see how their claims hold up to actual data.
www.patreon.com/posts/why-bi...
Why Big Wellness Hates Ozempic | Conspirituality
Get more from Conspirituality on Patreon
www.patreon.com
December 30, 2024 at 4:15 PM
Ozempic might be all the rage among people who want to lose weight, but wellness influencers and MAHA acolytes are raging against the antidiabetic medication.
I look into recent statements by RFK Jr and Calley Means to see how their claims hold up to actual data.
www.patreon.com/posts/why-bi...
I look into recent statements by RFK Jr and Calley Means to see how their claims hold up to actual data.
www.patreon.com/posts/why-bi...
WRITERS: anyone else taking Semaglutide (Ozempic™, Wegovy™, Rybelsus™, etc) and finding it demotivates you for writing?
GLP-1 agonists aren't just antidiabetic drugs that cause weight loss, they also seem to reduce reward-seeking behaviour, eg. alcoholism. And for me, writing has always been …
GLP-1 agonists aren't just antidiabetic drugs that cause weight loss, they also seem to reduce reward-seeking behaviour, eg. alcoholism. And for me, writing has always been …
October 10, 2023 at 8:50 AM
WRITERS: anyone else taking Semaglutide (Ozempic™, Wegovy™, Rybelsus™, etc) and finding it demotivates you for writing?
GLP-1 agonists aren't just antidiabetic drugs that cause weight loss, they also seem to reduce reward-seeking behaviour, eg. alcoholism. And for me, writing has always been …
GLP-1 agonists aren't just antidiabetic drugs that cause weight loss, they also seem to reduce reward-seeking behaviour, eg. alcoholism. And for me, writing has always been …
And you thought #metformin lowered glucose via the liver? Here loss-of-function and gain-of-function studies suggest that VMH Rap1 is indispensable for the antidiabetic effects of metformin in mice #diabetes www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
July 30, 2025 at 6:11 PM
And you thought #metformin lowered glucose via the liver? Here loss-of-function and gain-of-function studies suggest that VMH Rap1 is indispensable for the antidiabetic effects of metformin in mice #diabetes www.science.org/doi/10.1126/...
#Medsky In Nov 2019, my serious lifelong asthma literally disappeared a couple days after I started on liraglutide. (It returned exactly a year later when I had to have an operation and got moderate COVID during it.) No docs believed me. That disbelief should end now: jamanetwork.com/journals/jam...
Antidiabetic Medication and Asthma Attacks
This cohort study examines the association of treatment with metformin and add-on antidiabetic medications with asthma attacks.
jamanetwork.com
December 1, 2024 at 6:24 PM
#Medsky In Nov 2019, my serious lifelong asthma literally disappeared a couple days after I started on liraglutide. (It returned exactly a year later when I had to have an operation and got moderate COVID during it.) No docs believed me. That disbelief should end now: jamanetwork.com/journals/jam...
Weight-loss jabs may be good for mental health, research shows
Weight-loss jabs may be good for mental health, research shows
Swiss study finds wellbeing and life quality can be improved more than with insulin and other antidiabetic drugs
Weight loss jabs may be good for people’s mental health as well as helping curb their appetite, according to research.
A study by scientists from the University of Bern in Switzerland has found that appetite-suppressing injections also improve mood, wellbeing and quality of life more than insulin and other antidiabetic drugs. Continue reading...
www.theguardian.com
May 10, 2025 at 10:34 PM
Weight-loss jabs may be good for mental health, research shows
Antidiabetic Medication and #Asthma Attacks: Clinical Practice Research Datalink (CPRD) cohort: #metformin was associated with a lower rate of #asthma attacks, with further reductions with the use of #GLP-1RA. jamanetwork.com/journals/jam...
Author interview: edhub.ama-assn.org/jn-learning/...
Author interview: edhub.ama-assn.org/jn-learning/...
Antidiabetic Medication and Asthma Attacks
This cohort study examines the association of treatment with metformin and add-on antidiabetic medications with asthma attacks.
jamanetwork.com
November 19, 2024 at 2:53 AM
Antidiabetic Medication and #Asthma Attacks: Clinical Practice Research Datalink (CPRD) cohort: #metformin was associated with a lower rate of #asthma attacks, with further reductions with the use of #GLP-1RA. jamanetwork.com/journals/jam...
Author interview: edhub.ama-assn.org/jn-learning/...
Author interview: edhub.ama-assn.org/jn-learning/...
The race to develop small-molecule alternatives to peptide-based weight-loss and antidiabetes drugs isn’t over, but a leader and a laggard have emerged. cen.acs.org/pharmaceutic... 🧪 #biosky
Lilly touts results for once-daily weight-loss and antidiabetic pill
As Pfizer pulls a candidate from the market, Lilly expects its pill to get approved next year
cen.acs.org
April 20, 2025 at 2:37 PM
The race to develop small-molecule alternatives to peptide-based weight-loss and antidiabetes drugs isn’t over, but a leader and a laggard have emerged. cen.acs.org/pharmaceutic... 🧪 #biosky
A new review from Melbourne ME/CFS Collaboration, in collaboration with Collaborative Center at Montreal, highlights the potential of metformin, an antidiabetic agent, as a treatment for #MECFS and #LongCOVID.
👉 Read the full publication: ow.ly/uXQJ50WVZax
👉 Read the full publication: ow.ly/uXQJ50WVZax
September 12, 2025 at 6:00 PM
A new review from Melbourne ME/CFS Collaboration, in collaboration with Collaborative Center at Montreal, highlights the potential of metformin, an antidiabetic agent, as a treatment for #MECFS and #LongCOVID.
👉 Read the full publication: ow.ly/uXQJ50WVZax
👉 Read the full publication: ow.ly/uXQJ50WVZax
Quantifying the Provenance-to-Function Gap in Antidiabetic Peptide Prediction: Homology-Aware Evaluation and the ADP-Hybrid Baseline https://www.biorxiv.org/content/10.64898/2026.09.25.754557v1
October 2, 2026 at 1:45 AM
Quantifying the Provenance-to-Function Gap in Antidiabetic Peptide Prediction: Homology-Aware Evaluation and the ADP-Hybrid Baseline https://www.biorxiv.org/content/10.64898/2026.09.25.754557v1
T0d: #NephJC
Even with the pleiad of the new antidiabetic drugs, metformin is probably the most prescribed oral antidiabetic worldwide, especially in lower income settings
drc.bmj.com/content/...
Even with the pleiad of the new antidiabetic drugs, metformin is probably the most prescribed oral antidiabetic worldwide, especially in lower income settings
drc.bmj.com/content/...
April 16, 2025 at 1:10 AM
T0d: #NephJC
Even with the pleiad of the new antidiabetic drugs, metformin is probably the most prescribed oral antidiabetic worldwide, especially in lower income settings
drc.bmj.com/content/...
Even with the pleiad of the new antidiabetic drugs, metformin is probably the most prescribed oral antidiabetic worldwide, especially in lower income settings
drc.bmj.com/content/...
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
July 31, 2025 at 1:50 PM
Low-dose metformin requires brain Rap1 for its antidiabetic action | Science Advances www.science.org/doi/10.1126/...
How can #SeleniumNanoparticles become more biocompatible for #biomedical use?
This review highlights bio-SeNPs from bacteria, algae, fungi and plants, emphasizing their #antioxidant, antimicrobial, #antidiabetic and #anticancer potential.
#NanotechnologyReviews: doi.org/10.1515/ntre...
This review highlights bio-SeNPs from bacteria, algae, fungi and plants, emphasizing their #antioxidant, antimicrobial, #antidiabetic and #anticancer potential.
#NanotechnologyReviews: doi.org/10.1515/ntre...
September 30, 2026 at 6:01 AM
How can #SeleniumNanoparticles become more biocompatible for #biomedical use?
This review highlights bio-SeNPs from bacteria, algae, fungi and plants, emphasizing their #antioxidant, antimicrobial, #antidiabetic and #anticancer potential.
#NanotechnologyReviews: doi.org/10.1515/ntre...
This review highlights bio-SeNPs from bacteria, algae, fungi and plants, emphasizing their #antioxidant, antimicrobial, #antidiabetic and #anticancer potential.
#NanotechnologyReviews: doi.org/10.1515/ntre...
🧵 [4/6]
Triphala: Traditional GI tonic now backed by antioxidant & antidiabetic clinical findings!
🌐 #Triphala #GutHealth #Ayurveda @manjeet786.bsky.social @diegogarotooficial.bsky.social @rachel-garcia.bsky.social @nimoh.bsky.social @georgeradics.bsky.social @mquigley1963.bsky.social
Triphala: Traditional GI tonic now backed by antioxidant & antidiabetic clinical findings!
🌐 #Triphala #GutHealth #Ayurveda @manjeet786.bsky.social @diegogarotooficial.bsky.social @rachel-garcia.bsky.social @nimoh.bsky.social @georgeradics.bsky.social @mquigley1963.bsky.social
October 12, 2025 at 11:49 AM
🧵 [4/6]
Triphala: Traditional GI tonic now backed by antioxidant & antidiabetic clinical findings!
🌐 #Triphala #GutHealth #Ayurveda @manjeet786.bsky.social @diegogarotooficial.bsky.social @rachel-garcia.bsky.social @nimoh.bsky.social @georgeradics.bsky.social @mquigley1963.bsky.social
Triphala: Traditional GI tonic now backed by antioxidant & antidiabetic clinical findings!
🌐 #Triphala #GutHealth #Ayurveda @manjeet786.bsky.social @diegogarotooficial.bsky.social @rachel-garcia.bsky.social @nimoh.bsky.social @georgeradics.bsky.social @mquigley1963.bsky.social
Antidiabetic injection approved in Canada to reduce risk of non-fatal heart attacks
www.saltwire.com/halifax/news...
www.saltwire.com/halifax/news...
Antidiabetic injection approved in Canada to reduce risk of non-fatal heart attacks | SaltWire
A drug used to help Canadians lose weight has now been approved to reduce the risk of non-fatal heart attacks.
Novo Nordisk Canada says in a news release ...
www.saltwire.com
November 27, 2024 at 9:39 PM
Antidiabetic injection approved in Canada to reduce risk of non-fatal heart attacks
www.saltwire.com/halifax/news...
www.saltwire.com/halifax/news...
Quantifying the Provenance-to-Function Gap in Antidiabetic Peptide Prediction: Homology-Aware Evaluation and the ADP-Hybrid Baseline https://www.biorxiv.org/content/10.64898/2026.09.25.754557v1
October 2, 2026 at 1:45 AM
Quantifying the Provenance-to-Function Gap in Antidiabetic Peptide Prediction: Homology-Aware Evaluation and the ADP-Hybrid Baseline https://www.biorxiv.org/content/10.64898/2026.09.25.754557v1
This study in particular compared GLP-1 RA vs insulin in patients who were naive to antidiabetic medications at the time of prescription. Do you think there might be some unmeasured differences in the type of patients who get INSULIN as the first therapy for their newly diagnosed T2DM?
March 6, 2025 at 9:15 PM
This study in particular compared GLP-1 RA vs insulin in patients who were naive to antidiabetic medications at the time of prescription. Do you think there might be some unmeasured differences in the type of patients who get INSULIN as the first therapy for their newly diagnosed T2DM?