Ummmmmmm basophils are kinda fire tbh
November 25, 2024 at 1:15 AM
Ummmmmmm basophils are kinda fire tbh
Dear immunologists & cell biologists:
If you haven't seen "Cells at Work!", you should absolutely check it out, available now on Netflix. Season 2 is launching soon.
It features anthropomorphic immune cells fighting infections.
Basophils only speak in poem form.
Dendritic cells guard doors.
If you haven't seen "Cells at Work!", you should absolutely check it out, available now on Netflix. Season 2 is launching soon.
It features anthropomorphic immune cells fighting infections.
Basophils only speak in poem form.
Dendritic cells guard doors.
January 19, 2025 at 9:00 PM
Dear immunologists & cell biologists:
If you haven't seen "Cells at Work!", you should absolutely check it out, available now on Netflix. Season 2 is launching soon.
It features anthropomorphic immune cells fighting infections.
Basophils only speak in poem form.
Dendritic cells guard doors.
If you haven't seen "Cells at Work!", you should absolutely check it out, available now on Netflix. Season 2 is launching soon.
It features anthropomorphic immune cells fighting infections.
Basophils only speak in poem form.
Dendritic cells guard doors.
Stop talking trash about immune cells!
B cells MAKE ANTIBODIES
T cells HAVE MEMORY
Macrophages SIGNAL
Neutrophils PHAGOCYTOSE
Basophils
Dendritic cells PRESENT ANTIGEN
B cells MAKE ANTIBODIES
T cells HAVE MEMORY
Macrophages SIGNAL
Neutrophils PHAGOCYTOSE
Basophils
Dendritic cells PRESENT ANTIGEN
December 7, 2024 at 12:24 AM
Stop talking trash about immune cells!
B cells MAKE ANTIBODIES
T cells HAVE MEMORY
Macrophages SIGNAL
Neutrophils PHAGOCYTOSE
Basophils
Dendritic cells PRESENT ANTIGEN
B cells MAKE ANTIBODIES
T cells HAVE MEMORY
Macrophages SIGNAL
Neutrophils PHAGOCYTOSE
Basophils
Dendritic cells PRESENT ANTIGEN
Basophils may be rare, but their complexity is anything but, this review highlights their developmental pathways, newly identified progenitors, and unexpected heterogeneity revealed by single-cell tools. 🧬
vist.ly/5472c
#Immunology #Basophils
vist.ly/5472c
#Immunology #Basophils
The ontogenesis and heterogeneity of basophils
Summary. Basophils are the rarest leukocytes, but they have essential roles in protection against helminths, allergic disorders, autoimmune diseases, and s
doi.org
May 14, 2026 at 4:37 PM
Basophils may be rare, but their complexity is anything but, this review highlights their developmental pathways, newly identified progenitors, and unexpected heterogeneity revealed by single-cell tools. 🧬
vist.ly/5472c
#Immunology #Basophils
vist.ly/5472c
#Immunology #Basophils
Don’t let her bully you! Basophils are the bomb.
November 25, 2024 at 1:22 AM
Don’t let her bully you! Basophils are the bomb.
Basophils may be rare, but they pack a punch!
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
June 22, 2025 at 12:37 PM
Basophils may be rare, but they pack a punch!
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
My yearly update of basic immunology slides, my yearly rant about how little we know about immunology.
Why do we get fevers?
What do basophils actually do?
Do eosinophils respond to IgE?
Immunology literature:
Why do we get fevers?
What do basophils actually do?
Do eosinophils respond to IgE?
Immunology literature:
Partridge I Dont Know GIF
Alt: Partridge I Dont Know GIF
media.tenor.com
February 23, 2025 at 8:46 PM
My yearly update of basic immunology slides, my yearly rant about how little we know about immunology.
Why do we get fevers?
What do basophils actually do?
Do eosinophils respond to IgE?
Immunology literature:
Why do we get fevers?
What do basophils actually do?
Do eosinophils respond to IgE?
Immunology literature:
⚕️ MedSky ⚕️
A Rare White Blood Cell Boosts Cancer-Fighting Immune Cells
A Rare White Blood Cell Boosts Cancer-Fighting Immune Cells
A Rare White Blood Cell Boosts Cancer-Fighting Immune Cells
Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy.
www.the-scientist.com
March 4, 2025 at 2:35 AM
⚕️ MedSky ⚕️
A Rare White Blood Cell Boosts Cancer-Fighting Immune Cells
A Rare White Blood Cell Boosts Cancer-Fighting Immune Cells
Jake, they are STICKING TOGETHER and also some kind of phils, like basophils or something is also high, and eosophils and I need water apparently
August 18, 2026 at 1:33 AM
Jake, they are STICKING TOGETHER and also some kind of phils, like basophils or something is also high, and eosophils and I need water apparently
Our brand new review on type 2 immunity in malaria with terrific colleagues Renee Tsolis and Adrian Piliponsky highlighting the roles of mast cells and basophils in orchestrating the host response to infection and parasite transmission to Anopheles mosquitoes.
The type 2 immune response in gut homeostasis and parasite transmission in malaria
Malaria predisposes to concomitant bacteremia, resulting in increased mortality risk. Previous studies indicated that malaria causes structural changes in the intestine, induces tolerogenic immune responses, inhibits neutrophil recruitment, suppresses innate synthesis of IFN-γ, dysregulates mast cells (MCs) and basophils, and induces Th2-type immune responses. These can reduce parasite control while increasing enteropathogenic dissemination. Moreover, there is growing evidence that Th2 immunity, while protecting the host from overwhelming inflammation, may also contribute to increased parasite transmission. This review explores the roles of the regulatory immune response in bacterial coinfections and parasite transmission in malaria.
www.cell.com
December 19, 2024 at 12:16 PM
Our brand new review on type 2 immunity in malaria with terrific colleagues Renee Tsolis and Adrian Piliponsky highlighting the roles of mast cells and basophils in orchestrating the host response to infection and parasite transmission to Anopheles mosquitoes.
Happy Donut Friday to these three! Zuza received an AHA for work on Piezo2, Wyatt received BOTH an AHA and a F31 for work on basophils, and Skylar received an F31 for work on lymphatic alpha globin! Honored to have them in lab! (Pic from 2024 NAVBO)
December 20, 2024 at 7:26 PM
Happy Donut Friday to these three! Zuza received an AHA for work on Piezo2, Wyatt received BOTH an AHA and a F31 for work on basophils, and Skylar received an F31 for work on lymphatic alpha globin! Honored to have them in lab! (Pic from 2024 NAVBO)
Bart Lambrecht's team showed some beautiful data about IL-33 activated basophils in regulating Th2 entry into the lung and promoting asthma. Super important study in uncoupling whether Benralizumab works via eos or basophils in clinic. [6/n]
rupress.org/jem/article/...
rupress.org/jem/article/...
Interleukin-33–activated basophils promote asthma by regulating Th2 cell entry into lung tissue
The role of basophils in asthma is unclear. Here, Schuys and Brenis et al. show that they control the extravasation of pathogenic effector Th2 cells into t
rupress.org
October 3, 2024 at 7:57 PM
Bart Lambrecht's team showed some beautiful data about IL-33 activated basophils in regulating Th2 entry into the lung and promoting asthma. Super important study in uncoupling whether Benralizumab works via eos or basophils in clinic. [6/n]
rupress.org/jem/article/...
rupress.org/jem/article/...
Notch-activated basophils support intestinal CD4+ T cell fate and function during Trichuris muris infection
www.mucosalimmunology.org/article/S193...
www.mucosalimmunology.org/article/S193...
June 9, 2025 at 2:06 PM
Notch-activated basophils support intestinal CD4+ T cell fate and function during Trichuris muris infection
www.mucosalimmunology.org/article/S193...
www.mucosalimmunology.org/article/S193...
Single-cell omics-based characterization of human basophils reveals two transcriptionally distinct populations https://www.biorxiv.org/content/10.1101/2025.02.20.639059v1
February 26, 2025 at 7:27 AM
Single-cell omics-based characterization of human basophils reveals two transcriptionally distinct populations https://www.biorxiv.org/content/10.1101/2025.02.20.639059v1
Basophils infiltrate wounds to promote the resolution and healing in both adult and aged mice @jem.org
@inserm.fr rupress.org/jem/article-...
@inserm.fr rupress.org/jem/article-...
March 26, 2026 at 8:10 PM
Basophils infiltrate wounds to promote the resolution and healing in both adult and aged mice @jem.org
@inserm.fr rupress.org/jem/article-...
@inserm.fr rupress.org/jem/article-...
This secondary wave isn't caused by eating the food again. Instead, it is driven by the original activation event: delayed, newly synthesized inflammatory mediators from mast cells and basophils, paired with a late-phase influx of immune cells.
September 28, 2026 at 3:52 PM
This secondary wave isn't caused by eating the food again. Instead, it is driven by the original activation event: delayed, newly synthesized inflammatory mediators from mast cells and basophils, paired with a late-phase influx of immune cells.
This new review explores the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer - check it out @discovimmunol.bsky.social
Basophils may be rare, but they pack a punch!
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
This new review in Discovery Immunology dives into the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer.
📖 Open Access: https://bit.ly/4kMgDML
June 24, 2025 at 12:14 PM
This new review explores the ontogenesis & heterogeneity of basophils, revealing their surprising roles beyond allergies - from immune regulation to cancer - check it out @discovimmunol.bsky.social
"blood levels of basophils...regularly fluctuate with estrogen levels monthly (& those cells concentrate in the uterus for part of the cycle), & that estrogen rapidly releases histamine from uterine tissue...& we feel there is good evidence for a higher histamine pool in women"
September 24, 2026 at 12:05 AM
"blood levels of basophils...regularly fluctuate with estrogen levels monthly (& those cells concentrate in the uterus for part of the cycle), & that estrogen rapidly releases histamine from uterine tissue...& we feel there is good evidence for a higher histamine pool in women"
Dr. Bart Lambrecht from the VIB center 🇧🇪 will be presenting his work on "Adaptive immunity during asthma". Check his recent study on how Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue: pubmed.ncbi.nlm.nih.gov/39297875/
#EMBOBarrierTissues
#EMBOBarrierTissues
May 15, 2025 at 7:02 AM
Dr. Bart Lambrecht from the VIB center 🇧🇪 will be presenting his work on "Adaptive immunity during asthma". Check his recent study on how Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue: pubmed.ncbi.nlm.nih.gov/39297875/
#EMBOBarrierTissues
#EMBOBarrierTissues
Basophils obviously BASOPHIL.
Where else do you think all that basophil comes from???
Where else do you think all that basophil comes from???
December 7, 2024 at 1:10 AM
Basophils obviously BASOPHIL.
Where else do you think all that basophil comes from???
Where else do you think all that basophil comes from???
Interesting! α-Gal–specific mAbs from B cells of individuals who have been exposed to malaria suppress the activation of basophils sensitized with serum from patients with α-Gal syndrome. New intervention to prevent α-Gal allergy?
tinyurl.com/yr5hsssr
#glycotime
tinyurl.com/yr5hsssr
#glycotime
September 4, 2026 at 5:40 PM
Interesting! α-Gal–specific mAbs from B cells of individuals who have been exposed to malaria suppress the activation of basophils sensitized with serum from patients with α-Gal syndrome. New intervention to prevent α-Gal allergy?
tinyurl.com/yr5hsssr
#glycotime
tinyurl.com/yr5hsssr
#glycotime
every damn time i get a CBC with auto diff, i get:
high neutrophils %
low lymphocytes %
low monocytes %
normal basophils %
normal eosinophils %
but ALL the absolute values are ALWAYS NORMAL
…how does THAT work
high neutrophils %
low lymphocytes %
low monocytes %
normal basophils %
normal eosinophils %
but ALL the absolute values are ALWAYS NORMAL
…how does THAT work
February 21, 2026 at 8:42 PM
every damn time i get a CBC with auto diff, i get:
high neutrophils %
low lymphocytes %
low monocytes %
normal basophils %
normal eosinophils %
but ALL the absolute values are ALWAYS NORMAL
…how does THAT work
high neutrophils %
low lymphocytes %
low monocytes %
normal basophils %
normal eosinophils %
but ALL the absolute values are ALWAYS NORMAL
…how does THAT work
And yes it is more complicated than "just" mast cells - for example, platelets and basophils are also implicated in allergy - but mast cells are everywhere and key players in all this with many very safe treatments
September 21, 2026 at 5:26 PM
And yes it is more complicated than "just" mast cells - for example, platelets and basophils are also implicated in allergy - but mast cells are everywhere and key players in all this with many very safe treatments