Carbapenem-resistant Klebsiella pneumoniae has emerged as a major cause of healthcare-associated infections, driven by the global dissemination of high-risk clones. Because chlorhexidine is widely use...

Background/Objectives: Delivery format may change the resources consumed by surgical skin antisepsis even when the antiseptic is unchanged. We compared two workflows using identical 2% chlorhexidine in 70% isopropyl alcohol: a single-use pre-filled applicator and our center’s bulk-bottle protocol. Methods: Single-center, non-randomized pilot micro-costing study (hospital perspective, €2024) of 20 elective abdominal procedures (10 per workflow) performed by non-overlapping surgeon groups. Time was measured stepwise to completion of application, excluding the air-drying interval; waste was weighed. Results: Two bulk-protocol steps, decanting onto a cloth and blotting excess with gauze (39.8 s combined), have no applicator counterpart. Residual alcoholic chlorhexidine was 72.8% lower and total waste 27.9% lower (−42.3 g; 95% CI −62.1 to −22.6). Materials differed by €1.17 per procedure (€3.26 on the same regulatory basis), a difference that reverses if reprocessing is valued below about 78% of its average allocated cost. Aggregate workflow time differed by −29.8 s (95% CI −61.4 to −1.9) and total cost, 85% of it time valued and realizable only if released minutes become usable activity, by −€7.57 (−14.38 to −1.56). Case mix biased both in favor of the applicator: among unilateral hernia repairs (seven vs. four) they fell to −7.3 s (−33.0 to +19.6) and −€2.74 (−8.26 to +3.05), whereas waste differences were unchanged. Operator nesting makes intervals for time, cost and liquid waste likely too narrow. Conclusions: With the same antiseptic, the applicator workflow removes two handling steps and was associated with less wasted antiseptic. Whether it saves time or money requires a study crossing operators over workflows and timing drying.

Read the full paper: Salivary microbiome responses to chlorhexidine and Coriandrum sativum essential oil mouthwashes in patients with periodontitis in a randomized 2-week clinical trial

Non Stinging Cleaning Wipes with Medicated Solution for the Topical Management of Skin Problems

Chlorhexidine Gluconate Cloth Market size is projected to reach USD 21.76 billion by 2035 from USD 11.47 billion in 2025, at a CAGR of 6.68% during the forecast 2025–2035.

Cat wound care requires gentle flushing with sterile saline or diluted chlorhexidine (0.05%). Never use hydrogen peroxide, alcohol, or human ointments like Neosporin (which contains Polymyxin B, toxic to felines). Because cat skin heals quickly over