物理特性からみるゲノム組織化
単一ヌクレオソームの凝集性を測定する手法Condense-seqを開発。この凝集性という物理特性が、ゲノムのコンパートメントや遺伝子発現を相関することを発見。生体においてはポリアミンが凝集性の制御に重要かも
面白い概念です、
www.nature.com/articles/s41...
単一ヌクレオソームの凝集性を測定する手法Condense-seqを開発。この凝集性という物理特性が、ゲノムのコンパートメントや遺伝子発現を相関することを発見。生体においてはポリアミンが凝集性の制御に重要かも
面白い概念です、
www.nature.com/articles/s41...
Native nucleosomes intrinsically encode genome organization principles - Nature
A technique called condense-seq has been developed to measure nucleosome condensability and used to show that mononucleosomes contain sufficient information to condense into large-scale compartments…
www.nature.com
May 8, 2025 at 10:01 AM
物理特性からみるゲノム組織化
単一ヌクレオソームの凝集性を測定する手法Condense-seqを開発。この凝集性という物理特性が、ゲノムのコンパートメントや遺伝子発現を相関することを発見。生体においてはポリアミンが凝集性の制御に重要かも
面白い概念です、
www.nature.com/articles/s41...
単一ヌクレオソームの凝集性を測定する手法Condense-seqを開発。この凝集性という物理特性が、ゲノムのコンパートメントや遺伝子発現を相関することを発見。生体においてはポリアミンが凝集性の制御に重要かも
面白い概念です、
www.nature.com/articles/s41...
#5amwritersclub
Still cold. Most of the snow is gone. Quiet.
Revision going well. At a seq where several POV chars interact & must cut, condense, & clarify. Wondering about a book chars mention—use a real western or create a fictional title & maybe write later?
#queerwriters #amwriting
Still cold. Most of the snow is gone. Quiet.
Revision going well. At a seq where several POV chars interact & must cut, condense, & clarify. Wondering about a book chars mention—use a real western or create a fictional title & maybe write later?
#queerwriters #amwriting
March 16, 2026 at 12:00 PM
#5amwritersclub
Still cold. Most of the snow is gone. Quiet.
Revision going well. At a seq where several POV chars interact & must cut, condense, & clarify. Wondering about a book chars mention—use a real western or create a fictional title & maybe write later?
#queerwriters #amwriting
Still cold. Most of the snow is gone. Quiet.
Revision going well. At a seq where several POV chars interact & must cut, condense, & clarify. Wondering about a book chars mention—use a real western or create a fictional title & maybe write later?
#queerwriters #amwriting
Here’s the secret to how #nucleosomes shape the #genome. In PNAS Journal Club: www.pnas.org/post/journal...
#histone #chromatin #GeneExpression #condense-seq #GeneActivity
#histone #chromatin #GeneExpression #condense-seq #GeneActivity
June 12, 2025 at 5:52 PM
Here’s the secret to how #nucleosomes shape the #genome. In PNAS Journal Club: www.pnas.org/post/journal...
#histone #chromatin #GeneExpression #condense-seq #GeneActivity
#histone #chromatin #GeneExpression #condense-seq #GeneActivity
Native nucleosomes intrinsically encode genome organization principles
Native nucleosomes intrinsically encode genome organization principles
Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08971-7 A technique called condense-seq has been developed to measure nucleosome condensability and used to show that mononucleosomes contain sufficient information to condense into large-scale compartments without requiring any external factors.
www.nature.com
May 7, 2025 at 3:55 PM
Native nucleosomes intrinsically encode genome organization principles
Another group showing this as well - connections aren't equal to volume. We should think about the physical properties of the genome as an emergent system to encode, execute, and store information simultaneously.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Native nucleosomes intrinsically encode genome organization principles - Nature
A technique called condense-seq has been developed to measure nucleosome condensability and used to show that mononucleosomes contain sufficient information to condense into large-scale compartments w...
www.nature.com
May 8, 2025 at 7:43 PM
Another group showing this as well - connections aren't equal to volume. We should think about the physical properties of the genome as an emergent system to encode, execute, and store information simultaneously.
www.nature.com/articles/s41...
www.nature.com/articles/s41...