#cytochromeP450
🧬 From oxidative stress and cell viability to drug-metabolizing enzymes, this study provides a comprehensive assessment of the safety and antimicrobial potential of the furin inhibitors MI-1851 and MI-2415. #PseudomonasAeruginosa #CytochromeP450
www.mdpi.com/2227-9059/12...
September 22, 2026 at 1:35 AM
NITheCS Colloquium: ‘Four Decades of Cytochrome P450 Research in Africa: Past, Present & Future’
🎙️ Prof Khajamohiddin Syed (UZ)
📅 Mon, 31 Aug
⏰ 16h00 SAST
📍 Attend in person or online
buff.ly/OLzOQaF
#CytochromeP450 #Bioinformatics #Biotechnology #ComputationalBiology #PrecisionMedicine
August 25, 2026 at 9:11 AM
Therapeutic and Safety Evaluation of Enhydra fluctuans Lour. and Ipomoea aquatica Forssk. as Acetylcholinesterase, Butyrylcholinesterase, β‐Secretase, and CytochromeP450 Inhibitors Using In Vitro and UPLC–QTOF–MS‐Based Molecular Docking ... #ChemBiodivers onlinelibrary.wiley.com/doi/10.1002/...
Therapeutic and Safety Evaluation of Enhydra fluctuans Lour. and Ipomoea aquatica Forssk. as Acetylcholinesterase, Butyrylcholinesterase, β‐Secretase, and CytochromeP450 Inhibitors Using In Vitro and UPLC–QTOF–MS‐Based Molecular Docking and Dynamic Simulation Study
Considering the multi-targeted drug approach, Enhydra fluctuans and Ipomoea aquatica were comprehensively investigated for their acetylcholinesterase, butyrylcholinesterase, and β-secretase enzyme in...
onlinelibrary.wiley.com
December 5, 2025 at 9:05 PM
The reduced unit-cell dimensions of cryo crystals of statin-bound CYP105A1 resulted in increased symmetry interactions, which induced cis–trans conversion of the C-terminal peptide bond of Pro142 #CYP105A1 #CytochromeP450 #Statins doi.org/10.1107/S205...
October 21, 2025 at 2:50 PM
#FruitRes
Researchers identify 28 cytochrome P450 genes in apple, with MdCYP86A21 enhancing drought & salt stress tolerance, offering a key target for breeding resilient crops.
Details: https://maxapress.com/article/doi/10.48130/frures-0024-0024
#Apple #CytochromeP450
March 2, 2026 at 8:50 AM
“#Grapefruit has a high volume of compounds called #furanocoumarins, which are designed to protect the fruit from fungal infections. When u ingest grapefruit, those furanocoumarins take your #cytochromeP450 #enzymes offline": https://buff.ly/3WC8lNp #medications
Grapefruit Is One of the Weirdest Fruits on the Planet
From its name, to its hazy origins, to its drug interactions, there's a lot going on beneath that thick rind.
buff.ly
January 26, 2025 at 11:30 PM
Recent Advances in Cytochrome P450 Engineering

📢 Biocatalysis and Biotransformation Congress 2026

🗓️ October 21–22, 2026

📍 San Francisco, California, USA

🏢 Organized by Sciinov Group

#Biocatalysis #Biotransformation #CytochromeP450

#EnzymeEngineering #DirectedEvolution #GreenChemistry
March 23, 2026 at 4:01 AM
This study identifies the binding affinities and catalytic orientations of #ClavicepsPurpurea #CytochromeP450 with #Alachlor derivatives, establishing a structural framework for enzyme-led #herbicide #Bioremediation.

#OpenAccess in Open Chemistry: doi.org/10.1515/chem...
July 6, 2026 at 1:15 PM
Online now - the Spotlight "Upcycling #lignin with a controlled burn" from Jennifer DuBois.

#CYPenzymes #CytochromeP450 #Biocatalysis #Bioreactor

Read it here: authors.elsevier.com/a/1lFS93S6Gf...
June 12, 2025 at 3:32 PM
24th ICCP450 meeting June to 4th July 2025 30 at @unibe.ch is being generously supported by a grant to @pandeylab.bsky.social by 🙏
@snsf.ch #SNSF #Switzerland. 🌍Join us in Bern. Register: iccp450bern.unibe.ch #Science #Heme #CytochromeP450 #P450
24th International Conference on Cytochrome P450
ICCP450Bern.unibe.ch
May 15, 2025 at 7:13 AM
🐻 Get ready, #P450 peeps! for guru David (aka @p450nelson.bsky.social )! #ICCP450! 🎉 He literally wrote the book (well, the website!) on P450 nomenclature 🧬 – foundational work on drug metabolism, toxicology genomics! 🗓️ #P450 #CytochromeP450 #DrugMetabolism #Pharmacology 🔬 www.iccp450bern.unibe.ch
March 27, 2025 at 4:03 PM
📢 Get ready to hear Prof. Steve Sligar at 24th #ICCP450 meeting in #Bern, #Switzerland! 🇨🇭🗓️ 🎉
🔬✨ Don't miss the chance to learn from a true leader in #cytochromeP450 !
➡️ info: iccp450bern.unibe.ch
See you in Bern! 👋 #DrugMetabolism #Biochemistry #Science #P450 🧪🧬
March 22, 2025 at 7:37 PM
Here's the expanded CYP-ADRs dataset on adverse drug reactions for cytochrome P450 substrates (drugs) with ideas behind this work.

Dataset: github.com/jhylin/Adver...

Ideas: jhylin.github.io/Data_in_life...

#prescription_drugs #cytochromep450 #adverse_reactions #cheminformatics
April 27, 2025 at 11:40 PM
Full-length structure of CPR-containing self-sufficient cytochrome P450
C.-C., Chen et al.
Paper
Details
#CytochromeP450 #CPR #Biochemistry
December 18, 2025 at 9:01 AM
Use of a cytochrome P450 humanised mouse model to refine schistosomiasis drug discovery.
Aubrey, W. et al.
Paper
Details
#Schistosomiasis #CytochromeP450 #DrugDiscovery
December 15, 2025 at 9:04 AM