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Someone is sexting with me on #NiteFlirt, and you can too at https://www.niteflirt.com/chat/35233912nzq-carmel-glaze?un=db26!
October 12, 2026 at 11:51 AM
adapubs.bsky.social
Podocyte multiomics showed concordant hyperglycemia-induced hypomethylation and gene activation, supporting the biological plausibility of the blood-derived risk score.

Read here ➡️ doi.org/10.2337/db26-0015
This image is an infographic illustrating a blood-derived four-locus methylation score that identifies the risk of diabetic kidney disease (DKD) progression. It includes a diagram of kidneys at the top, which indicates increasing DKD progression risk from left to right, labeled LR (low risk), MR (moderate risk), HR (high risk), and VHR (very high risk). The study involved a discovery and validation phase with 10 individuals with Type 1 diabetes (T1D) and 330 individuals with T1D. Four genes—SLC444A4, FSTL4, ICA1, and PTK2—are associated with the methylation score, influencing progression risk in human kidney cells, including podocytes and proximal tubular cells. Charts and arrows indicate methylation and gene expression changes.
October 12, 2026 at 7:25 PM
adapubs.bsky.social
Microgel technology could offer a more favorable risk-benefit profile by reducing infection risks, organ toxicity, and tumorgenicity associated with the use of systemic immunosuppression.

Read here ➡️ doi.org/10.2337/db26-0280
Diagram illustrating a scientific process to enhance islet function and viability. The left section shows prosurvival molecules and immunomodulatory properties, leading to recruitment of T regulatory cells. The middle section features engineered microgels with SA-protein protecting co-transplanted islets. The right section depicts the reduction of cytotoxic T cells and increase in T regulatory cells, highlighting improved islet function. Arrows indicate the flow of the process across the sections.
October 9, 2026 at 8:45 PM
lindabrooke6.bsky.social
www.ft.com/content/db26... What does the bond sell-off mean for the global economy? Live Q&A
What does the bond sell-off mean for the global economy? Live Q&A
Economics leader writer Tej Parikh and European economics commentator Martin Sandbu will answer your questions now
www.ft.com
October 1, 2026 at 12:25 PM
adapubs.bsky.social
Higher insulin doses were associated with increased cardiac sympathetic predominance in adults with type 1 diabetes under free-living conditions.
#T1D #Insulin

Read here ➡️ doi.org/10.2337/db26-0456
This image is a research flowchart about the effects of therapeutic insulin on cardiac sympathetic predominance in people with type 1 diabetes. The diagram shows the timeline and methods used, including insulin administration and wearable heart rate sensors. Key observations noted include changes in the low-frequency/high-frequency ratio in different sleep phases with insulin dosage variations.
October 2, 2026 at 12:15 AM
adapubs.bsky.social
Pericytes are a significant endogenous source of hepatocyte growth factor, coupling the islet microvasculature to insulin production and glucose homeostasis.

Read here ➡️ doi.org/10.2337/db26-0227
Diagram comparing embryogenesis, pregnancy, and adulthood stages in relation to β-cells. In both stages, pericytes release HGF, activating c-Met on β-cells. During embryogenesis and pregnancy, this interaction promotes β-cell expansion, shown by a red circular arrow. In adulthood, it facilitates insulin production, with Pdx1, Insa, and Slc2a2 involved in the process.
October 1, 2026 at 8:20 PM
adapubs.bsky.social
Changes in specific subcellular lipid storage help explain muscle insulin sensitization following lifestyle interventions.

Read here ➡️ doi.org/10.2337/db26-0239
This image is a graph with three sections labeled A, B, and C, comparing levels of TAG in whole muscle, SARC, and Mito/ER, respectively. Each section shows data for "Control," "Weight loss," and "Exercise" groups, with "Pre" and "Post" conditions. Bars display varying heights, with dotted black lines indicating significant differences and asterisks marking statistical significance.
September 30, 2026 at 7:55 PM
fraochfurze.bsky.social
So thrilled to share my contribution to the @desertbus.org craftalong for 2026!

I spent so many hours carefully cutting and layering paper to create this diorama of Hornet's Bellhome. I poured all my love into this project and am so happy with how she came out!

#desertbus #db26 #silksong
September 25, 2026 at 4:56 PM
cerebrodigital.net
Terapias con islotes pancreáticos derivados de células madre lograron independencia de la insulina en pacientes con diabetes tipo 1, marcando un avance histórico. 

DOI: 10.1016/j.cell.2024.09.004
DOI: 10.1056/NEJMoa2506549
DOI: 10.2337/db26-0013

Te explicamos:
cerebrodigital.net/revierte...
September 26, 2026 at 10:00 AM
adapubs.bsky.social
⭐ 📖 Paper of the Month: Oct

Islet-Targeted ZnT8 Antibodies Protect Pancreatic β-Cells From Inflammatory Stress ➡️ https://doi.org/10.2337/db26-0183

Articles chosen 🗓️ monthly & 🆓 online #paperofthemonth #diabetes
A call out for the journal's Paper of the Month
September 25, 2026 at 1:15 PM
adapubs.bsky.social
findings suggest that novel therapeutic strategies targeting protein Kla modification could be significant in the clinical management of DbCM.

Read here ➡️ doi.org/10.2337/db26-0432
This diagram illustrates a biological study involving db/db mice, C57BL/6 mice, and primary cardiomyocytes. It shows the process of inducing cardiac conditions through high glucose and palmitate exposure. Key pathways and proteins include Cryab, Hspb1, ERK, and MAPK, with arrows indicating activation or inhibition. The study focuses on cardiac effects such as LVFS, LVFE, and myocardial performance index.
September 25, 2026 at 8:00 PM
adapubs.bsky.social
Wearable-derived behavioral targets may be practical solutions for reducing UPF-associated diabetes risk and supporting diabetes prevention.

Read here ➡️ doi.org/10.2337/db26-0395
An infographic titled "Associations of Ultraprocessed Food Intake, Wearable-Measured Lifestyle Factors, and Genetic Susceptibility With Incident Type 2 Diabetes." It includes sections on study overview, independent associations, lifestyle-gene analysis, and joint analysis. It features Biobank data with 56,964 participants. Graphs compare associations of ultraprocessed food intake with diabetes, moderated by physical activity and genetic risk levels. Conclusion highlights a positive link between ultraprocessed food intake and type 2 diabetes risk.
September 24, 2026 at 9:05 PM
zdogg667.bsky.social
Shadow vs Mewtwo | DEATH BATTLE!: I dreamed of this match going from one of the worst episodes of DB to one of its best......AND IT SUCCEEDED!

Everyone involved should be proud of this. Definitely not just a DB26 highlight but a series highlight and I'm so happy that's the case.
September 22, 2026 at 2:58 AM
adapubs.bsky.social
It seems likely that an abnormal α-cell response to amino acid concentrations precedes an abnormal response to glucose alone.

Read here ➡️ https://doi.org/10.2337/db26-0502
This image is a scientific diagram illustrating the effect of obesity on the alpha-cell response to hyperglycemia with amino acid presence. It includes two line graphs comparing "Lean Participants" and "Participants with Obesity" on their glucagon secretion rate (GSR) in response to varying glucose concentrations, with lines for saline and amino acid mixtures. Text descriptions and endpoints of the study are detailed on the left.
September 19, 2026 at 11:50 PM
adapubs.bsky.social
Longitudinal protein measurements identify additional novel disease biomarkers and disparate biological pathways compared with single measurement analyses. #T2D

Read here ➡️ doi.org/10.2337/db26-0148
The image is a scientific diagram comparing single-time point and longitudinal repeated proteomics analyses from MESA and UK Biobank (UKB) studies. It shows the process and data flow for incident type 2 diabetes (T2D) biomarker analysis, highlighting pathways and comparison analyses. The left side details the MESA study with proteomics measurements across exams, while the right side shows UKB with a baseline measurement. Additional diagrams include a Mendelian randomization chart and a Venn diagram for pathway enrichment analyses.
September 17, 2026 at 10:50 PM
sievertschreiber.bsky.social
“Desert Bus for Hope is the internet’s oldest still running charity marathon.”

#desertbus #db26

youtu.be/GJUiJ5GvZhQ

desertbus.org
What is Desert Bus for Hope? 2026 Edition
YouTube video by DesertBusForHope
youtu.be
September 16, 2026 at 9:46 PM
adapubs.bsky.social
#T1D may induce a state of premature immunosenescence, even in relatively young individuals. Immunosenescence is associated with an impaired immune response, reduced tolerance, and production of proinflammatory mediators.

Read here ➡️ doi.org/10.2337/db26-0159

The image is a flow chart illustrating a self-reinforcing cycle. At the top, there is a box labeled "Immunosenescence," with details about T cells. Below, a triangle labeled "T1D" includes aspects like hyperglycemia and chronic inflammation. Two other boxes labeled "Cell senescence" and "Inflammaging" are connected with arrows, each describing characteristics like chronic inflammation and senescence. Arrows indicate the cyclical relationship among all elements.
September 11, 2026 at 10:15 PM
oekrainevandaag.bsky.social
🔗 press.un.org/en/2026/db26...
September 9, 2026 at 9:55 AM
adapubs.bsky.social
Accelerated brain aging appears to affect people with diabetes regardless of neuropathic complications.

Read here ➡️ doi.org/10.2337/db26-0305
This image is an infographic detailing a study on brain age gap (BAG) in individuals with diabetes. It includes brain MRI data from 48 healthy controls, 53 people with painless diabetic peripheral neuropathy (DPN), and 46 with painful DPN. The methods involve whole-brain BAG, multiple linear regression, and nerve conduction velocity, highlighting clinical variables such as age, sex, HbA1c, diabetes duration, and others. The results indicate BAG group comparisons and show that diabetes duration predominantly drives BAG differences, with no apparent contribution of neuropathic pain.
September 10, 2026 at 9:10 PM
adapubs.bsky.social
Altering palmitoylation in fat may preserve β-cell function in insulin resistance.

Read here ➡️ https://doi.org/10.2337/db26-0023
The image illustrates a biological process involving white adipose tissue and APT1 deficiency in mice over time, affecting glucose tolerance. At the top, two mice are depicted: one with normal conditions and another with a crossed-out APT1, signifying APT1 deficiency. Below them, a scale balances insulin resistance on the left, with a crossed-out APT1, and glucose-stimulated insulin secretion on the right, featuring preserved β-cell mass. Insulinogenic extracellular vesicles are shown beneath the scale.
September 9, 2026 at 12:05 AM
huisvrouwblues.bsky.social
Hij had het vast niet door, maar Spinvis kreeg alle duiven uit het Julianapark als een dolle rondjes aan het vliegen. Is weer eens wat anders dan een moshpit #dB26
September 6, 2026 at 7:10 PM
huisvrouwblues.bsky.social
Invaller Kasba’s Jah past prima bij het zonnige weer. Rustig opstarten bij dB’s Buiten #dB26
September 6, 2026 at 12:50 PM
huisvrouwblues.bsky.social
Henk Koorn die zich afvraagt wat wij op een zondagmiddag een donker hol doen als de zon schijnt. Nou, Hallo Venray kijken natuurlijk #dB26
September 6, 2026 at 4:45 PM
huisvrouwblues.bsky.social
Clitteband houdt je vast deze middag. Leuk! #dB26
September 6, 2026 at 4:48 PM
huisvrouwblues.bsky.social
Blue Grass Boogiemen: prima voor een zondagmiddag #dB26
September 6, 2026 at 4:43 PM