I’d put it differently. EBV is almost certainly necessary (but not sufficient) for MS. So prevent EBV and you prevent MS. But most people who get EBV (and most people do) never get MS. EBV puts the bullet in the chamber but things unknown pull the trigger.
February 13, 2026 at 6:07 AM
I’d put it differently. EBV is almost certainly necessary (but not sufficient) for MS. So prevent EBV and you prevent MS. But most people who get EBV (and most people do) never get MS. EBV puts the bullet in the chamber but things unknown pull the trigger.
September 23, 2026 at 6:06 PM
99.99% of people who get EBV don’t get HL, but most people who get HL wouldn’t have gotten it without first getting EBV.
September 8, 2025 at 1:16 AM
99.99% of people who get EBV don’t get HL, but most people who get HL wouldn’t have gotten it without first getting EBV.
guess what reactivates EBV
NEW: The Epstein-Barr virus lies dormant in the bodies of billions of people - but for some it is linked to serious chronic and even deadly conditions, including cancers. Now scientists have identified 22 genes that could help identify those most at risk.
www.ft.com/content/815d...
www.ft.com/content/815d...
Scientists link 22 genes to deadly risks from common virus
Research probes persistence of Epstein-Barr virus that can cause serious illnesses, including cancers
www.ft.com
January 29, 2026 at 8:48 AM
guess what reactivates EBV
More smoking gun evidence for the role of Epstein-Barr virus (EBV) in multiple sclerosis. Elevated EBV-specific lymphocytes in cerebrospinal fluid
www.pnas.org/doi/abs/10.1...
www.pnas.org/doi/abs/10.1...
January 8, 2024 at 11:20 PM
More smoking gun evidence for the role of Epstein-Barr virus (EBV) in multiple sclerosis. Elevated EBV-specific lymphocytes in cerebrospinal fluid
www.pnas.org/doi/abs/10.1...
www.pnas.org/doi/abs/10.1...
I was diagnosed with CFS, renamed ME, wait for it… in 1983, after a very severe non-mononucleosis EBV infection, that fully incapacitated me. The EBV laid dormant, but reared its ugly head during my infection w Lyme/Babesia complicating a full recovery. TY for this story @georgemonbiot.bsky.social
Here's today's column on the astonishing, ongoing mistreatment of people with #ME/CFS. Please spread it far and wide: the only thing which can break the media's wall of indifference is seeing an article about the issue go viral. Thank you. 1/2
www.theguardian.com/commentisfre...
www.theguardian.com/commentisfre...
Abandoned, dismissed and gaslighted: there is no excuse for the way ME sufferers have been betrayed | George Monbiot
Changes in guidance and science seem to have little impact on millions of devastated lives. It’s a social crisis playing out behind closed doors, says Guardian columnist George Monbiot
www.theguardian.com
September 26, 2026 at 8:52 AM
I was diagnosed with CFS, renamed ME, wait for it… in 1983, after a very severe non-mononucleosis EBV infection, that fully incapacitated me. The EBV laid dormant, but reared its ugly head during my infection w Lyme/Babesia complicating a full recovery. TY for this story @georgemonbiot.bsky.social
Blood samples from multiple sclerosis—MS—patients showed Epstein-Barr virus lytic activity in immune cells ~3 months before MS relapse. Lytic activity means the process of EBV reactivating inside infected white blood cells, shifting from dormancy to assembling new viruses that break free of cells👇
EBV reactivation priming of the peripheral immune system in multiple sclerosis relapse - Nature Medicine
Increased expression of EBV reactivation genes in B cells and MS risk genes targeted by the EBV protein EBNA-2 precedes MS attacks, linking EBV reactivation and genetic risk to the development of MS r...
www.nature.com
September 26, 2026 at 5:53 PM
Blood samples from multiple sclerosis—MS—patients showed Epstein-Barr virus lytic activity in immune cells ~3 months before MS relapse. Lytic activity means the process of EBV reactivating inside infected white blood cells, shifting from dormancy to assembling new viruses that break free of cells👇
EBV also precursor to Burkitt's Lymphoma. 🙋♂️ for some.
February 13, 2026 at 6:51 AM
EBV also precursor to Burkitt's Lymphoma. 🙋♂️ for some.
In 2022, the necessary but not sufficient cause of MS was proven to my satisfaction: Epstein-Barr Virus (EBV). In contrast to what RFK Jr. would have you believe, an EBV vaccine could possibly eliminate MS from the face of the earth. Vaccines don’t cause it.
www.science.org/content/arti...
www.science.org/content/arti...
Two decades of soldiers’ medical records implicate common virus in multiple sclerosis
Vaccines under development against Epstein-Barr virus might prevent rare, devastating disease
www.science.org
July 8, 2025 at 10:07 PM
In 2022, the necessary but not sufficient cause of MS was proven to my satisfaction: Epstein-Barr Virus (EBV). In contrast to what RFK Jr. would have you believe, an EBV vaccine could possibly eliminate MS from the face of the earth. Vaccines don’t cause it.
www.science.org/content/arti...
www.science.org/content/arti...
Immunsystem dauerhaft „verwirren“.
Platz 3) Epstein-Barr-Virus (EBV) (häufigster mononucleosis-assoziierter Trigger):
Sehr häufig. Viele Patienten berichten von einer Mononukleose („Drüsenfieber“) oder einem EBV-Reaktivationsschub als Beginn.
Platz 3) Epstein-Barr-Virus (EBV) (häufigster mononucleosis-assoziierter Trigger):
Sehr häufig. Viele Patienten berichten von einer Mononukleose („Drüsenfieber“) oder einem EBV-Reaktivationsschub als Beginn.
September 20, 2026 at 1:03 PM
Immunsystem dauerhaft „verwirren“.
Platz 3) Epstein-Barr-Virus (EBV) (häufigster mononucleosis-assoziierter Trigger):
Sehr häufig. Viele Patienten berichten von einer Mononukleose („Drüsenfieber“) oder einem EBV-Reaktivationsschub als Beginn.
Platz 3) Epstein-Barr-Virus (EBV) (häufigster mononucleosis-assoziierter Trigger):
Sehr häufig. Viele Patienten berichten von einer Mononukleose („Drüsenfieber“) oder einem EBV-Reaktivationsschub als Beginn.
EBV-Seq enables identification of EBV-infected cells. Therefore patients with lupus were shown to have been infected with very specific memory B cells, reprogrammed, and act as drivers for autoimmunity overall.
September 23, 2026 at 6:40 PM
EBV-Seq enables identification of EBV-infected cells. Therefore patients with lupus were shown to have been infected with very specific memory B cells, reprogrammed, and act as drivers for autoimmunity overall.
#Medsky🧪 #IDsky #Microsky #publichealth EBV is extremely common. Carried through saliva, #herpesvirus can be easily transmitted by sharing drinks, food utensils, or kissing.
It's the virus that most commonly causes mononucleosis (mono)
@natureportfolio.nature.com
www.nature.com/articles/s41...
It's the virus that most commonly causes mononucleosis (mono)
@natureportfolio.nature.com
www.nature.com/articles/s41...
EBV reactivation priming of the peripheral immune system in multiple sclerosis relapse - Nature Medicine
Increased expression of EBV reactivation genes in B cells and MS risk genes targeted by the EBV protein EBNA-2 precedes MS attacks, linking EBV reactivation and genetic risk to the development of MS r...
www.nature.com
September 26, 2026 at 5:33 AM
#Medsky🧪 #IDsky #Microsky #publichealth EBV is extremely common. Carried through saliva, #herpesvirus can be easily transmitted by sharing drinks, food utensils, or kissing.
It's the virus that most commonly causes mononucleosis (mono)
@natureportfolio.nature.com
www.nature.com/articles/s41...
It's the virus that most commonly causes mononucleosis (mono)
@natureportfolio.nature.com
www.nature.com/articles/s41...
UCLouvain researchers review how EBV can persist for life, reprogram B cells, and trigger autoimmunity through molecular mimicry and immune dysregulation.
In Long COVID, EBV reactivation is plausible but evidence remains early.
www.mdpi.com/1999-4915/18...
In Long COVID, EBV reactivation is plausible but evidence remains early.
www.mdpi.com/1999-4915/18...
www.mdpi.com
September 26, 2026 at 1:13 PM
UCLouvain researchers review how EBV can persist for life, reprogram B cells, and trigger autoimmunity through molecular mimicry and immune dysregulation.
In Long COVID, EBV reactivation is plausible but evidence remains early.
www.mdpi.com/1999-4915/18...
In Long COVID, EBV reactivation is plausible but evidence remains early.
www.mdpi.com/1999-4915/18...
Whoah
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 13, 2025 at 11:05 PM
Whoah
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
(I've been thinking about the potential for tx of #MECFS by EBV vaccination for some time. Talked to a pharma rep about it at one of these conferences...)
She is doing a trial soon for lupus using the same EBV vaccine as that used for MS.
She is doing a trial soon for lupus using the same EBV vaccine as that used for MS.
September 23, 2026 at 6:42 PM
(I've been thinking about the potential for tx of #MECFS by EBV vaccination for some time. Talked to a pharma rep about it at one of these conferences...)
She is doing a trial soon for lupus using the same EBV vaccine as that used for MS.
She is doing a trial soon for lupus using the same EBV vaccine as that used for MS.
And beyond that if anyone has questions we should ask a virologist, I’m just a neuroscientist from a small town whose mind has been blown by the MS/EBV studies
February 13, 2026 at 5:57 AM
And beyond that if anyone has questions we should ask a virologist, I’m just a neuroscientist from a small town whose mind has been blown by the MS/EBV studies
Today in @nature.com, we describe how discarded reads in biobank-scale WGS can help resolve the genetic predictors and consequences of Epstein-Barr Virus (EBV) infection.
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
Population-scale sequencing resolves determinants of persistent EBV DNA - Nature
Population-scale WGS reveals genetic determinants of persistent EBV DNA, linking immune regulation—especially antigen processing and MHC class II variation—to EBV persistence and heterogeneous di...
www.nature.com
January 28, 2026 at 5:07 PM
Today in @nature.com, we describe how discarded reads in biobank-scale WGS can help resolve the genetic predictors and consequences of Epstein-Barr Virus (EBV) infection.
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
A new study provides evidence of a biological mechanism for how Epstein-Barr Virus (EBV) may trigger lupus.
EBV seems to reprogram B-cells at the beginning of a cascade that ultimately results in autoimmunity.
The authors mention that EBV is a cause of MS, and may be related to LongCOVID.
EBV seems to reprogram B-cells at the beginning of a cascade that ultimately results in autoimmunity.
The authors mention that EBV is a cause of MS, and may be related to LongCOVID.
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 13, 2025 at 1:45 AM
A new study provides evidence of a biological mechanism for how Epstein-Barr Virus (EBV) may trigger lupus.
EBV seems to reprogram B-cells at the beginning of a cascade that ultimately results in autoimmunity.
The authors mention that EBV is a cause of MS, and may be related to LongCOVID.
EBV seems to reprogram B-cells at the beginning of a cascade that ultimately results in autoimmunity.
The authors mention that EBV is a cause of MS, and may be related to LongCOVID.
I got mono (EBV) in 1982, was diagnosed with chronically active EBV in 1985, and was diagnosed with lupus (after years of positive ANA & anti-DNA tests) in 2012. Suffice it to say that EBV has had a profound affect on my life. Oh, and EBV gave my late husband type 1 diabetes at age 20.
Researchers also believe EBV plays a role in a wide range of serious conditions — from lupus and certain cancers to rheumatoid arthritis — and may trigger some cases of chronic fatigue syndrome. Some suspect it could be a hidden driver of long Covid.
www.bloomberg.com/news/article...
www.bloomberg.com/news/article...
The Silent Virus Behind Mono Is Now a Prime Suspect in Major Diseases
Epstein-Barr virus, which causes glandular fever, was once dismissed as a rite of passage. Scientists now link it to cancer and multiple sclerosis.
www.bloomberg.com
June 8, 2025 at 8:23 AM
I got mono (EBV) in 1982, was diagnosed with chronically active EBV in 1985, and was diagnosed with lupus (after years of positive ANA & anti-DNA tests) in 2012. Suffice it to say that EBV has had a profound affect on my life. Oh, and EBV gave my late husband type 1 diabetes at age 20.
„EBV wurde jahrelang als milde Übergangserkrankung abgetan. Diese Sichtweise ändert sich jedoch rapide, seit eine Studie aus dem Jahr 2022 eindeutige Belege dafür lieferte, dass EBV ein Auslöser von Multipler Sklerose ist.“
Wie persistierende Viruserkrankungen die menschliche Gesundheit unbemerkt schädigen können
EBV, das stille Virus hinter Mononukleose, ist jetzt ein Hauptverdächtiger bei schweren Krankheiten: Wissenschaftler bringen es heute mit Krebs, MS, Lupus, Long COVID und ME/CFS in …
EBV, das stille Virus hinter Mononukleose, ist jetzt ein Hauptverdächtiger bei schweren Krankheiten: Wissenschaftler bringen es heute mit Krebs, MS, Lupus, Long COVID und ME/CFS in …
December 26, 2025 at 10:39 PM
„EBV wurde jahrelang als milde Übergangserkrankung abgetan. Diese Sichtweise ändert sich jedoch rapide, seit eine Studie aus dem Jahr 2022 eindeutige Belege dafür lieferte, dass EBV ein Auslöser von Multipler Sklerose ist.“
12/1 Entwicklung von Präventionsstrategien, wie z. B. Impfstoffen gegen EBV, und zielgerichteten Therapien zur Behandlung EBV-assoziierter Erkrankungen.
May 28, 2025 at 11:26 AM
12/1 Entwicklung von Präventionsstrategien, wie z. B. Impfstoffen gegen EBV, und zielgerichteten Therapien zur Behandlung EBV-assoziierter Erkrankungen.
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...
🧪🧠Cell www.cell.com/cell/fulltex...
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
January 15, 2026 at 1:41 AM
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...
🧪🧠Cell www.cell.com/cell/fulltex...
And covid may trigger EBV reactivation causing long covid
February 13, 2026 at 7:21 AM
And covid may trigger EBV reactivation causing long covid
Images are very slow to load on the NIH wireless, so let me just narrate.
While everyone is exposed to EBV, people with lupus respond immunologically differently to EBV than people without lupus do.
While everyone is exposed to EBV, people with lupus respond immunologically differently to EBV than people without lupus do.
September 23, 2026 at 6:33 PM
Images are very slow to load on the NIH wireless, so let me just narrate.
While everyone is exposed to EBV, people with lupus respond immunologically differently to EBV than people without lupus do.
While everyone is exposed to EBV, people with lupus respond immunologically differently to EBV than people without lupus do.