A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
Single-cell profiling of the human endometrium in polycystic ovary syndrome - Nature Medicine
A transcriptomic atlas of the endometrium of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets.
go.nature.com
April 6, 2025 at 1:22 AM
A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
Day 3 #SciArtSeptember: sanguine. This detail of the endometrium on my uterus #embroidery, Bleeding Vessel (2022), is definitely sanguine. #SciArt
September 3, 2026 at 6:14 PM
Day 3 #SciArtSeptember: sanguine. This detail of the endometrium on my uterus #embroidery, Bleeding Vessel (2022), is definitely sanguine. #SciArt
In a period, bleeding happens when the endometrium is shed. It happens after ovulation. In animals with an estrus cycle, bleeding sometimes occurs - but it happens *before* ovulation. It's a sign that the endometrium is building up.
January 30, 2025 at 12:05 PM
In a period, bleeding happens when the endometrium is shed. It happens after ovulation. In animals with an estrus cycle, bleeding sometimes occurs - but it happens *before* ovulation. It's a sign that the endometrium is building up.
Having a menstrual cycle is very rare in nature. A period is a phase in the ovarian cycle where the endometrium - the lining of the uterus - is shed. It will then regenerate each cycle, because for whatever reason, embryos only implant in fresh endometrium.
January 30, 2025 at 11:51 AM
Having a menstrual cycle is very rare in nature. A period is a phase in the ovarian cycle where the endometrium - the lining of the uterus - is shed. It will then regenerate each cycle, because for whatever reason, embryos only implant in fresh endometrium.
At this point, either pregnancy occurs, or if it does not, hormonal changes signal that the endometrium isn't needed this cycle.
In animals with a menstrual cycle, at this point menstruation is triggered. In animals with an estrus cycle, the endometrium is reabsorbed.
In animals with a menstrual cycle, at this point menstruation is triggered. In animals with an estrus cycle, the endometrium is reabsorbed.
January 30, 2025 at 11:58 AM
At this point, either pregnancy occurs, or if it does not, hormonal changes signal that the endometrium isn't needed this cycle.
In animals with a menstrual cycle, at this point menstruation is triggered. In animals with an estrus cycle, the endometrium is reabsorbed.
In animals with a menstrual cycle, at this point menstruation is triggered. In animals with an estrus cycle, the endometrium is reabsorbed.
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
Single-cell profiling of the human endometrium in polycystic ovary syndrome - Nature Medicine
A transcriptomic atlas of the endometrium of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets.
go.nature.com
March 29, 2025 at 10:32 PM
A transcriptomic atlas of the endometrium (the inner lining of the uterus) of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets, according to a paper in Nature Medicine. 🧪
In the interests of fairness, we'll start with what the diagram got right. Sometimes there is endometrium inside a menstrual cup, because endometrial cells form a part of menstrual fluid. That's it, that's the post on what the image got right.
June 18, 2026 at 10:39 AM
In the interests of fairness, we'll start with what the diagram got right. Sometimes there is endometrium inside a menstrual cup, because endometrial cells form a part of menstrual fluid. That's it, that's the post on what the image got right.
On that same theme . . .
The Living Endometrium
The Living Endometrium
Boyz II Menstruation
Feminize a band name
N’SYNC Menstrual Cycles
N’SYNC Menstrual Cycles
September 27, 2026 at 8:11 AM
On that same theme . . .
The Living Endometrium
The Living Endometrium
Dogs are in the majority of mammalian species that have an estrus cycle, not a menstrual cycle. They don't have periods, they instead reabsorb their endometrium.
January 30, 2025 at 12:03 PM
Dogs are in the majority of mammalian species that have an estrus cycle, not a menstrual cycle. They don't have periods, they instead reabsorb their endometrium.
In individuals with uterus didelphys - double uteruses - both uteruses usually behave as expected. Each uterus has an endometrium and a muscular wall, and the endometrium reacts to hormones with a menstrual cycle.
April 9, 2025 at 10:52 AM
In individuals with uterus didelphys - double uteruses - both uteruses usually behave as expected. Each uterus has an endometrium and a muscular wall, and the endometrium reacts to hormones with a menstrual cycle.
Single-cell profiling of the human endometrium in polycystic ovary syndrome. #NatureMedicine
This study presents a comprehensive cellular atlas of the endometrium during the proliferative phase, comparing women with PCOS to healthy controls.
www.nature.com/articles/s41...
This study presents a comprehensive cellular atlas of the endometrium during the proliferative phase, comparing women with PCOS to healthy controls.
www.nature.com/articles/s41...
Single-cell profiling of the human endometrium in polycystic ovary syndrome - Nature Medicine
A transcriptomic atlas of the endometrium of women with polycystic ovary syndrome uncovers both disease signatures and potential therapeutic targets.
www.nature.com
March 25, 2025 at 5:48 AM
Single-cell profiling of the human endometrium in polycystic ovary syndrome. #NatureMedicine
This study presents a comprehensive cellular atlas of the endometrium during the proliferative phase, comparing women with PCOS to healthy controls.
www.nature.com/articles/s41...
This study presents a comprehensive cellular atlas of the endometrium during the proliferative phase, comparing women with PCOS to healthy controls.
www.nature.com/articles/s41...
why is my endometrium so fucked up
January 22, 2025 at 2:46 PM
why is my endometrium so fucked up
They’re booking me in for an ablation. Goodbye endometrium. You sucked.
April 15, 2025 at 1:44 PM
They’re booking me in for an ablation. Goodbye endometrium. You sucked.
This could be a game-changer: Fusobacterium infection of the endometrium might contribute to endometriosis.
In a study of 79 human patients Fusobacterium was more frequent in patients with endometriosis (64·3%) than in controls.
In mice, antibiotic treatment appeared to be effective.
In a study of 79 human patients Fusobacterium was more frequent in patients with endometriosis (64·3%) than in controls.
In mice, antibiotic treatment appeared to be effective.
Bacterial infection linked to endometriosis
A translational study has suggested that Fusobacterium infection of the endometrium
might contribute to the pathogenesis of endometriosis.
www.thelancet.com
December 22, 2025 at 2:03 PM
This could be a game-changer: Fusobacterium infection of the endometrium might contribute to endometriosis.
In a study of 79 human patients Fusobacterium was more frequent in patients with endometriosis (64·3%) than in controls.
In mice, antibiotic treatment appeared to be effective.
In a study of 79 human patients Fusobacterium was more frequent in patients with endometriosis (64·3%) than in controls.
In mice, antibiotic treatment appeared to be effective.
Aside from this, the phases of the estrus cycle are similar to the menstrual cycle. One or more ovarian follicles develop, and the endometrium begins to build up. The animal ovulates, releasing one or more eggs.
January 30, 2025 at 11:58 AM
Aside from this, the phases of the estrus cycle are similar to the menstrual cycle. One or more ovarian follicles develop, and the endometrium begins to build up. The animal ovulates, releasing one or more eggs.
The uterus consists of two main parts: an outside which consists of smooth muscle tissue, and a lining called the endometrium. The endometrium is responsive to hormones. Oestrogen tells it to proliferate, and other hormones tell it to shed. When it sheds, that's a period.
April 9, 2025 at 10:48 AM
The uterus consists of two main parts: an outside which consists of smooth muscle tissue, and a lining called the endometrium. The endometrium is responsive to hormones. Oestrogen tells it to proliferate, and other hormones tell it to shed. When it sheds, that's a period.
The first slightly weird thing about elephant shrews is that they menstruate. Menstruation is rare in mammals, limited to most primates (including humans), some bats, spiny mice, as well as elephant shrews. All other mammals just reabsorb the endometrium if fertilisation doesn't occur.
August 19, 2025 at 10:47 AM
The first slightly weird thing about elephant shrews is that they menstruate. Menstruation is rare in mammals, limited to most primates (including humans), some bats, spiny mice, as well as elephant shrews. All other mammals just reabsorb the endometrium if fertilisation doesn't occur.
A lot of you clearly don't understand what ovaries do because holy shit the misinformation on this website right now.
Signed, someone without an endometrium or fallopian tubes.
Signed, someone without an endometrium or fallopian tubes.
May 5, 2026 at 3:12 AM
A lot of you clearly don't understand what ovaries do because holy shit the misinformation on this website right now.
Signed, someone without an endometrium or fallopian tubes.
Signed, someone without an endometrium or fallopian tubes.
What The Uterus Can Teach Us About Linear Game Design That Doesn't Suck
April 15, 2026 at 4:06 PM
What The Uterus Can Teach Us About Linear Game Design That Doesn't Suck
a field that had been
a vibrant mosaic
of orange
yellow & green
rusted overnight
becoming the same color
as red clay
each stem still stands
mimicking posts
of a weathered
wrought iron fence
encompassing
a vacant mausoleum
in nature
where endometrium
grows from dead husks
#Poetry
a vibrant mosaic
of orange
yellow & green
rusted overnight
becoming the same color
as red clay
each stem still stands
mimicking posts
of a weathered
wrought iron fence
encompassing
a vacant mausoleum
in nature
where endometrium
grows from dead husks
#Poetry
September 25, 2026 at 11:24 PM
a field that had been
a vibrant mosaic
of orange
yellow & green
rusted overnight
becoming the same color
as red clay
each stem still stands
mimicking posts
of a weathered
wrought iron fence
encompassing
a vacant mausoleum
in nature
where endometrium
grows from dead husks
#Poetry
a vibrant mosaic
of orange
yellow & green
rusted overnight
becoming the same color
as red clay
each stem still stands
mimicking posts
of a weathered
wrought iron fence
encompassing
a vacant mausoleum
in nature
where endometrium
grows from dead husks
#Poetry
I've menstruated chunks of endometrium bigger than that
July 24, 2025 at 10:10 PM
I've menstruated chunks of endometrium bigger than that
Day 21 #ArtAdventCalendar • This #SciArt #anatomy & #symptomatology #embroidery depicts my uterus with its fibroids, ovarian cysts, and endometrial cancer prior to my hysterectomy in 2022. Bleeding Vessel (2022).
You can read more about this piece here: liapas.com/2022/10/13/b...
You can read more about this piece here: liapas.com/2022/10/13/b...
December 21, 2025 at 4:01 PM
Day 21 #ArtAdventCalendar • This #SciArt #anatomy & #symptomatology #embroidery depicts my uterus with its fibroids, ovarian cysts, and endometrial cancer prior to my hysterectomy in 2022. Bleeding Vessel (2022).
You can read more about this piece here: liapas.com/2022/10/13/b...
You can read more about this piece here: liapas.com/2022/10/13/b...
my endometrium is falling out and i just cried at how tiny this tin is
October 20, 2023 at 12:12 PM
my endometrium is falling out and i just cried at how tiny this tin is