Treatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgA nephropathy #IgAN, leaving patients at risk of ESKD ca. 2026 from @asnpublications.bsky.social
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/42584957/
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/42584957/
October 3, 2026 at 12:38 AM
Treatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgA nephropathy #IgAN, leaving patients at risk of ESKD ca. 2026 from @asnpublications.bsky.social
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/42584957/
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/42584957/
【「抑うつ」でESKDリスク低？/Diab Med】Sep.30
英国プライマリケア医受診CKD [ステージ1-4] 58.769例解析——
・観察開始時、14%に「抑うつ」
・5.6年間に全体の3％が「末期腎疾患」に増悪。なおそれ以前に
43%が死亡。
・抑うつ「あり」で「なし」に比べ、ESKDの部分分布HRは0.67の有意低値。諸因子補正後も有意 [0.82]。
全文🔗 h1.nu/1zjbF
英国プライマリケア医受診CKD [ステージ1-4] 58.769例解析——
・観察開始時、14%に「抑うつ」
・5.6年間に全体の3％が「末期腎疾患」に増悪。なおそれ以前に
43%が死亡。
・抑うつ「あり」で「なし」に比べ、ESKDの部分分布HRは0.67の有意低値。諸因子補正後も有意 [0.82]。
全文🔗 h1.nu/1zjbF
<em>Diabetic Medicine</em> | Diabetes UK Journal | Wiley Online Library
Introduction Diabetes is the leading cause of end-stage kidney disease (ESKD; CKD stage 5). Depression is common among people with diabetes and CKD and is associated with poorer outcomes. However, i...
h1.nu
October 1, 2026 at 9:59 PM
【「抑うつ」でESKDリスク低？/Diab Med】Sep.30
英国プライマリケア医受診CKD [ステージ1-4] 58.769例解析——
・観察開始時、14%に「抑うつ」
・5.6年間に全体の3％が「末期腎疾患」に増悪。なおそれ以前に
43%が死亡。
・抑うつ「あり」で「なし」に比べ、ESKDの部分分布HRは0.67の有意低値。諸因子補正後も有意 [0.82]。
全文🔗 h1.nu/1zjbF
英国プライマリケア医受診CKD [ステージ1-4] 58.769例解析——
・観察開始時、14%に「抑うつ」
・5.6年間に全体の3％が「末期腎疾患」に増悪。なおそれ以前に
43%が死亡。
・抑うつ「あり」で「なし」に比べ、ESKDの部分分布HRは0.67の有意低値。諸因子補正後も有意 [0.82]。
全文🔗 h1.nu/1zjbF
【米国退役軍人CKD例でSGLT2阻害薬とGLP-1RAの腎保護作用を比較すると？/CJASN】Sep.29
米国退役軍人、ステージ3、4 CKDでSGLT2阻害薬開始の78,354例とGLP-RA開始28,365例、PS重み付比較——
・11カ月間の「ESKD・腎機能4割以上の持続的低下・死亡」に両
群間で有意差なし。
・一方、腎機能低下とESKDリスクはGLP-1RAで有意に高。
抄録🔗 x.gd/9kzOD
米国退役軍人、ステージ3、4 CKDでSGLT2阻害薬開始の78,354例とGLP-RA開始28,365例、PS重み付比較——
・11カ月間の「ESKD・腎機能4割以上の持続的低下・死亡」に両
群間で有意差なし。
・一方、腎機能低下とESKDリスクはGLP-1RAで有意に高。
抄録🔗 x.gd/9kzOD
Comparative Renal Effectiveness of GLP-1RA and... : Clinical Journal of the American Society of Nephrology
Objective:To address limited comparative evidence in older, clinically complex patients with type 2 diabetes and moderate-to-advanced chronic kidney...
x.gd
September 29, 2026 at 9:55 PM
【米国退役軍人CKD例でSGLT2阻害薬とGLP-1RAの腎保護作用を比較すると？/CJASN】Sep.29
米国退役軍人、ステージ3、4 CKDでSGLT2阻害薬開始の78,354例とGLP-RA開始28,365例、PS重み付比較——
・11カ月間の「ESKD・腎機能4割以上の持続的低下・死亡」に両
群間で有意差なし。
・一方、腎機能低下とESKDリスクはGLP-1RAで有意に高。
抄録🔗 x.gd/9kzOD
米国退役軍人、ステージ3、4 CKDでSGLT2阻害薬開始の78,354例とGLP-RA開始28,365例、PS重み付比較——
・11カ月間の「ESKD・腎機能4割以上の持続的低下・死亡」に両
群間で有意差なし。
・一方、腎機能低下とESKDリスクはGLP-1RAで有意に高。
抄録🔗 x.gd/9kzOD
Study in #ASNCJASN: In high-risk IgAN, RAAS inhibitors alone slowed eGFR decline to -4.5 mL/min/1.73 m² per year, well above the ≤1 mL/min/1.73 m² target needed to reduce ESKD risk, underscoring the need for disease-modifying therapies. kidney.pub/CJASN1130
September 26, 2026 at 4:30 PM
Study in #ASNCJASN: In high-risk IgAN, RAAS inhibitors alone slowed eGFR decline to -4.5 mL/min/1.73 m² per year, well above the ≤1 mL/min/1.73 m² target needed to reduce ESKD risk, underscoring the need for disease-modifying therapies. kidney.pub/CJASN1130
See our discussion from #NephJc with author
www.kidneymedicinejournal.org/article/S259... in @kidneymed.bsky.social
www.kidneymedicinejournal.org/article/S259... in @kidneymed.bsky.social
September 25, 2026 at 12:54 AM
See our discussion from #NephJc with author
www.kidneymedicinejournal.org/article/S259... in @kidneymed.bsky.social
www.kidneymedicinejournal.org/article/S259... in @kidneymed.bsky.social
Follow BD's FLOW of innovation, insight and shared clinical experience.
Explore key topics in AV access at the ESKD Symposium on 7 October with Prof. Matteo Tozzi at 10:30 and advanced vessel preparation strategies at the PAD Symposium on 8 October with Dr. Marc Sirvent at 09:30
#FLOW@ESVS
Sponsored
Explore key topics in AV access at the ESKD Symposium on 7 October with Prof. Matteo Tozzi at 10:30 and advanced vessel preparation strategies at the PAD Symposium on 8 October with Dr. Marc Sirvent at 09:30
#FLOW@ESVS
Sponsored
September 22, 2026 at 9:40 AM
Follow BD's FLOW of innovation, insight and shared clinical experience.
Explore key topics in AV access at the ESKD Symposium on 7 October with Prof. Matteo Tozzi at 10:30 and advanced vessel preparation strategies at the PAD Symposium on 8 October with Dr. Marc Sirvent at 09:30
#FLOW@ESVS
Sponsored
Explore key topics in AV access at the ESKD Symposium on 7 October with Prof. Matteo Tozzi at 10:30 and advanced vessel preparation strategies at the PAD Symposium on 8 October with Dr. Marc Sirvent at 09:30
#FLOW@ESVS
Sponsored
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In the largest U.S. study of ADPKD patients with ESKD, peritoneal dialysis (PD) was linked to lower mortality and a higher likelihood of kidney transplantation compared with hemodialysis. The findings in #ASNCJASN support PD as a safe dialysis option for patients with ADPKD. kidney.pub/CJASN1134
September 18, 2026 at 3:30 PM
In the largest U.S. study of ADPKD patients with ESKD, peritoneal dialysis (PD) was linked to lower mortality and a higher likelihood of kidney transplantation compared with hemodialysis. The findings in #ASNCJASN support PD as a safe dialysis option for patients with ADPKD. kidney.pub/CJASN1134
【SGLT2-i開始後「尿糖」陽性で臨床転帰「良」/JASN】Sep.17
米国、SGLT2-i開始45.711例 [対象疾患不詳] 解析——
・58%で開始後6カ月以内に「尿糖」陽性。
・「陽性」例では「陰性」例に比べ、IPTW補正後、「死亡」HRは
0.78、「HF入院」が0.87、「ESKD」も0.73の有意低値。
・「骨折」HRは1.00。
抄録🔗 x.gd/tMMEy
米国、SGLT2-i開始45.711例 [対象疾患不詳] 解析——
・58%で開始後6カ月以内に「尿糖」陽性。
・「陽性」例では「陰性」例に比べ、IPTW補正後、「死亡」HRは
0.78、「HF入院」が0.87、「ESKD」も0.73の有意低値。
・「骨折」HRは1.00。
抄録🔗 x.gd/tMMEy
September 17, 2026 at 9:54 PM
【SGLT2-i開始後「尿糖」陽性で臨床転帰「良」/JASN】Sep.17
米国、SGLT2-i開始45.711例 [対象疾患不詳] 解析——
・58%で開始後6カ月以内に「尿糖」陽性。
・「陽性」例では「陰性」例に比べ、IPTW補正後、「死亡」HRは
0.78、「HF入院」が0.87、「ESKD」も0.73の有意低値。
・「骨折」HRは1.00。
抄録🔗 x.gd/tMMEy
米国、SGLT2-i開始45.711例 [対象疾患不詳] 解析——
・58%で開始後6カ月以内に「尿糖」陽性。
・「陽性」例では「陰性」例に比べ、IPTW補正後、「死亡」HRは
0.78、「HF入院」が0.87、「ESKD」も0.73の有意低値。
・「骨折」HRは1.00。
抄録🔗 x.gd/tMMEy
Social determinants of health, particularly perceived discrimination, significantly increase the likelihood of patients on maintenance hemodialysis experiencing severe physical and psychological symptom clusters.
https://www.clinicalpainadvisor.com/news/perceived-discrimination-symptom-burden-eskd/
https://www.clinicalpainadvisor.com/news/perceived-discrimination-symptom-burden-eskd/
Perceived Discrimination Linked to Greater Symptom Burden in End-Stage Kidney Disease
Patients with end-stage kidney disease on hemodialysis who experience perceived discrimination have a higher burden of pain and anxiety.
www.clinicalpainadvisor.com
September 17, 2026 at 2:46 PM
Social determinants of health, particularly perceived discrimination, significantly increase the likelihood of patients on maintenance hemodialysis experiencing severe physical and psychological symptom clusters.
https://www.clinicalpainadvisor.com/news/perceived-discrimination-symptom-burden-eskd/
https://www.clinicalpainadvisor.com/news/perceived-discrimination-symptom-burden-eskd/
Kidney outcomes are shaped by more than biology. In #ASNCJASN study, among 30,498 ICU survivors of AKI, adverse SDOH including uninsured status and neighborhood deprivation were linked to higher risk of ESKD. Identifying these factors could improve post-discharge kidney care. kidney.pub/CJASN1141
September 10, 2026 at 4:32 PM
Kidney outcomes are shaped by more than biology. In #ASNCJASN study, among 30,498 ICU survivors of AKI, adverse SDOH including uninsured status and neighborhood deprivation were linked to higher risk of ESKD. Identifying these factors could improve post-discharge kidney care. kidney.pub/CJASN1141
He's a Epstein survivor telling about people like Donald Trump raping killing kids
youtube.com/watch?v=eSkD...
youtube.com/watch?v=eSkD...
🇺🇸🍊 Sascha Riley Full Interview (pt 1-6): Epstein PDF Ring (2026)
YouTube video by Bffr Moe
youtube.com
September 9, 2026 at 6:15 PM
He's a Epstein survivor telling about people like Donald Trump raping killing kids
youtube.com/watch?v=eSkD...
youtube.com/watch?v=eSkD...
Refractory lupus nephritis: national multicenter study. link.springer.com/article/10.1... #hvhebron #reu
Refractory lupus nephritis: national multicenter study - Internal and Emergency Medicine
Refractory lupus nephritis (LN) remains a major therapeutic challenge and a leading cause of progression to end-stage kidney disease (ESKD) in systemic lupus erythematosus (SLE). To characterize a lar...
link.springer.com
September 9, 2026 at 4:25 PM
Refractory lupus nephritis: national multicenter study. link.springer.com/article/10.1... #hvhebron #reu
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9/ Outcome
🫘Composite kidney disease progression : 📉40% decline in eGFR from baseline or the onset of ESKD (defined as eGFR <15mL/min/1.73m², dialysis initiation, or kidney transplantation)
👬Covariates:
Age, sex, BMI, albumin, proteinuria, eGFR, MAP, diabetes and MEST/C
🫘Composite kidney disease progression : 📉40% decline in eGFR from baseline or the onset of ESKD (defined as eGFR <15mL/min/1.73m², dialysis initiation, or kidney transplantation)
👬Covariates:
Age, sex, BMI, albumin, proteinuria, eGFR, MAP, diabetes and MEST/C
September 9, 2026 at 5:23 AM
9/ Outcome
🫘Composite kidney disease progression : 📉40% decline in eGFR from baseline or the onset of ESKD (defined as eGFR <15mL/min/1.73m², dialysis initiation, or kidney transplantation)
👬Covariates:
Age, sex, BMI, albumin, proteinuria, eGFR, MAP, diabetes and MEST/C
🫘Composite kidney disease progression : 📉40% decline in eGFR from baseline or the onset of ESKD (defined as eGFR <15mL/min/1.73m², dialysis initiation, or kidney transplantation)
👬Covariates:
Age, sex, BMI, albumin, proteinuria, eGFR, MAP, diabetes and MEST/C
A Girl with End-Stage Kidney Disease Due to Granulomatosis with Polyangiitis Presenting with Gastrointestinal Bleeding "a rare presentation"
A Girl with End-Stage Kidney Disease Due to Granulomatosis with Polyangiitis Presenting with Gastrointestinal Bleeding "a rare presentation" - PubMed
Granulomatosis with polyangiitis (GPA) is an uncommon vasculitis affecting small- and medium-sized vessels, predominantly in adults (average age approximately 45 years) and infrequently in children. It can involve multiple organ systems. In patients with end-stage kidney disease (ESKD) due to GPA, d …
pubmed.ncbi.nlm.nih.gov
September 7, 2026 at 5:34 PM
A Girl with End-Stage Kidney Disease Due to Granulomatosis with Polyangiitis Presenting with Gastrointestinal Bleeding "a rare presentation"
CMS isn’t even collecting race and ethnicity data on the 2728 form for end stage kidney disease. That’s been a primary source of research data in ESKD.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Nonreporting of Race and Ethnicity in Medical Research Harms Us All
At JAMA Internal Medicine, we have become increasingly aware that some US researchers are unable to report on race or ethnicity as demographic variables to describe their sample or to conduct stratifi...
jamanetwork.com
September 1, 2026 at 11:30 PM
CMS isn’t even collecting race and ethnicity data on the 2728 form for end stage kidney disease. That’s been a primary source of research data in ESKD.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
From Locked Out to Opting in: How the Cures Act Reshaped Medicare Advantage Utilization for Beneficiaries With End‐Stage Kidney Disease onlinelibrary.wiley.com/doi/10.1111/...
<em>Health Services Research</em> | AcademyHealth & HRET Journal | Wiley Online Library
Objective To describe how the characteristics of Medicare Advantage (MA) beneficiaries with end-stage kidney disease (ESKD) changed after the 21st Century Cures Act expanded MA eligibility, and to d...
onlinelibrary.wiley.com
August 30, 2026 at 2:44 PM
From Locked Out to Opting in: How the Cures Act Reshaped Medicare Advantage Utilization for Beneficiaries With End‐Stage Kidney Disease onlinelibrary.wiley.com/doi/10.1111/...
【透析例でもスタチンの適応があれば、LDL-Cは “The lower, the better”か/Atherosclerosis】Aug.25
台湾、スタチン服用の意地血液透析3,431例解析——
・到達LDL-C値「<55」mg/dLで「≧100 」に比べ「CV死亡」HR
は0.71の有意低値 [NNT不詳]。
・一方「MACE」は0.90で有意差なし。
・「総死亡」にも有意差なし [HRは0.80]。
抄録🔗. x.gd/d8L44
台湾、スタチン服用の意地血液透析3,431例解析——
・到達LDL-C値「<55」mg/dLで「≧100 」に比べ「CV死亡」HR
は0.71の有意低値 [NNT不詳]。
・一方「MACE」は0.90で有意差なし。
・「総死亡」にも有意差なし [HRは0.80]。
抄録🔗. x.gd/d8L44
The benefit of LDL-C levels below 55 mg/dL in ESKD patients under statin treatment: A target trial emulation study
Achieving optimal low-density lipoprotein cholesterol (LDL-C) levels through statin
therapy is a cornerstone of cardiovascular disease (CVD) prevention. However, its
benefit in end-stage kidney diseas...
x.gd
August 25, 2026 at 10:32 PM
【透析例でもスタチンの適応があれば、LDL-Cは “The lower, the better”か/Atherosclerosis】Aug.25
台湾、スタチン服用の意地血液透析3,431例解析——
・到達LDL-C値「<55」mg/dLで「≧100 」に比べ「CV死亡」HR
は0.71の有意低値 [NNT不詳]。
・一方「MACE」は0.90で有意差なし。
・「総死亡」にも有意差なし [HRは0.80]。
抄録🔗. x.gd/d8L44
台湾、スタチン服用の意地血液透析3,431例解析——
・到達LDL-C値「<55」mg/dLで「≧100 」に比べ「CV死亡」HR
は0.71の有意低値 [NNT不詳]。
・一方「MACE」は0.90で有意差なし。
・「総死亡」にも有意差なし [HRは0.80]。
抄録🔗. x.gd/d8L44
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Original: Drs. @karlynedwards.bsky.social, @liebschutz.bsky.social et al. found that patients with end-stage kidney disease face chronic pain viewed buprenorphine as a safer alternative to opioids, highlighting the need for better access and stigma-free pain care
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
A qualitative study examining barriers to buprenorphine for pain management in patients with end stage kidney disease undergoing hemodialysis
Chronic pain is common and burdensome among people with end stage kidney disease (ESKD). Pain management options are limited and prescription opioids are often used in this population, but carry…
www.jpain.org
August 7, 2026 at 3:00 AM
Original: Drs. @karlynedwards.bsky.social, @liebschutz.bsky.social et al. found that patients with end-stage kidney disease face chronic pain viewed buprenorphine as a safer alternative to opioids, highlighting the need for better access and stigma-free pain care
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
#Randomized Controlled Trial of Integrated #Kidney #Supportive Care in End-Stage Kidney Disease #ESKD
#VisualAbstract by @krishnadoctor1
https://www.kireports.org/article/S2468-0249(26)02928-1/fulltext
#VisualAbstract by @krishnadoctor1
https://www.kireports.org/article/S2468-0249(26)02928-1/fulltext
August 5, 2026 at 1:00 PM
#Randomized Controlled Trial of Integrated #Kidney #Supportive Care in End-Stage Kidney Disease #ESKD
#VisualAbstract by @krishnadoctor1
https://www.kireports.org/article/S2468-0249(26)02928-1/fulltext
#VisualAbstract by @krishnadoctor1
https://www.kireports.org/article/S2468-0249(26)02928-1/fulltext
10/ heart disease. More than 35M have chronic lung disease. More than 40M have diabetes. 37 M (> 1 in 7, says the NIH) have chronic kidney disease; relevant, when you're talking about dehydration risk.
🔹️Yet a huge number of these folks don't *think* they have
www.niddk.nih.gov/health-infor...
🔹️Yet a huge number of these folks don't *think* they have
www.niddk.nih.gov/health-infor...
Kidney Disease Statistics for the United States - NIDDK
Overview of kidney disease facts and statistics for the United States, including chronic kidney disease (CKD) and end-stage kidney disease (ESKD).
www.niddk.nih.gov
August 3, 2026 at 10:29 PM
10/ heart disease. More than 35M have chronic lung disease. More than 40M have diabetes. 37 M (> 1 in 7, says the NIH) have chronic kidney disease; relevant, when you're talking about dehydration risk.
🔹️Yet a huge number of these folks don't *think* they have
www.niddk.nih.gov/health-infor...
🔹️Yet a huge number of these folks don't *think* they have
www.niddk.nih.gov/health-infor...
Advances in the Diagnosis, Treatment and Prognosis of ANCA-Associated Glomerulonephritis
Advances in the Diagnosis, Treatment and Prognosis of ANCA-Associated Glomerulonephritis - PubMed
ANCA-associated vasculitis (AAV) with kidney involvement represents small-vessel vasculitis, characterized by rapidly progressive glomerulonephritis and a high risk of end-stage kidney disease (ESKD) ...
pubmed.ncbi.nlm.nih.gov
August 3, 2026 at 8:47 PM
Advances in the Diagnosis, Treatment and Prognosis of ANCA-Associated Glomerulonephritis