#glial
Great work from Amber Zimmerman (@atothezphd.bsky.social), Allan Pack and team.

Delighted to contribute to this preprint "DPYD links glial lipids and myelination to sleep duration".

@chopresearch.bsky.social @penngenetics.bsky.social

www.biorxiv.org/content/10.6...
www.biorxiv.org
November 3, 2026 at 5:15 PM
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling https://www.biorxiv.org/content/10.64898/2026.10.31.763276v1
November 3, 2026 at 7:47 AM
Neuronal and glial transcriptional states vary with proximity to tangle-bearing neurons in the human entorhinal cortex https://www.biorxiv.org/content/10.64898/2026.10.27.762234v1
November 2, 2026 at 2:15 AM
A Glial Interplay Regulates Junctional Architecture at the Blood-Brain Barrier of Drosophila
#Drosophila
A Glial Interplay Regulates Junctional Architecture at the Blood-Brain Barrier of Drosophila #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
November 2, 2026 at 6:24 PM
Corrigendum: Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model
#Drosophila
Corrigendum: Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
November 4, 2026 at 5:23 AM
Goat Milk-derived Extracellular Vesicles modulate glial responses in vitro and attenuate neuroinflammation in vivo https://www.biorxiv.org/content/10.64898/2026.10.26.761897v1
October 30, 2026 at 10:19 PM
Blue light compromises cellular fate of intrinsically photosensitive Müller glial cells in the developing chicken retina. https://www.biorxiv.org/content/10.64898/2026.10.26.753828v1
October 30, 2026 at 10:19 PM
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling https://www.biorxiv.org/content/10.64898/2026.10.31.763276v1
November 3, 2026 at 7:47 AM
Neuronal and glial transcriptional states vary with proximity to tangle-bearing neurons in the human entorhinal cortex https://www.biorxiv.org/content/10.64898/2026.10.27.762234v1
November 2, 2026 at 2:15 AM
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.31.763276v1
November 3, 2026 at 8:01 AM
Spatially resolved single-cell atlas reveals cortical glial reactivity associated with regions of neuronal growth programs in both hemispheres after stroke https://www.biorxiv.org/content/10.64898/2026.10.26.761917v1
October 30, 2026 at 10:19 PM
Sheng, L., Gao, J., Wei, Q., Gong, Y., Xu, Z. X. (2025). The glial UDP-glycosyltransferase Ugt35b regulates longevity by maintaining lipid homeostasis in Drosophila. Cell Rep, 44(1):115099 www.cell.com/cell-reports...
The glial UDP-glycosyltransferase Ugt35b regulates longevity by maintaining lipid homeostasis in Drosophila
Sheng et al. show that expression of the UDP-glycosyltransferase Ugt35b in glia is required for LD formation to support Drosophila lifespan. They demonstrated that glial Ugt35b regulates LD formation ...
www.cell.com
October 28, 2026 at 7:40 PM
Neuronal and glial transcriptional states vary with proximity to tangle-bearing neurons in the human entorhinal cortex #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.27.762234v1
November 2, 2026 at 5:02 AM
reliable diagnostic capacity was further confirmed in an independent external cohort. Single-cell and spatial transcriptomic profiling mapped these hub genes to endothelial, myeloid and glial cell populations residing within a dynamic inflammatory-vascular pathological niche in (🧵 5/9)
November 5, 2026 at 4:42 AM
CRV Science Wiki
🐙 Nervous System — The nervous system is the integrated network of electrically excitable neurons and supporting neuroglia (glial cells) that detects external and internal physiological stimuli, processes information via action potentia…

https://crvscience.com/wiki/nervous-system
CRV Science Wiki 🐙 Nervous System — The nervous system is the integrated network of electrically excitable neurons and supporting neuroglia (glial cells) that detects external and internal physiological stimuli, processes information via action potentials and chemical or...
crvscience.com
November 3, 2026 at 9:40 AM
Election Day Distraction: Good news on the dementia front. A drug already OK’d for human safety (for spinal cord injuries) turns out to be Very Promising for treatment of Alzheimer’s.

Yay, Science. Support Basic Science Research.
febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Repair of neuronal DNA damage in Alzheimer's disease by KCL-286. (A) Amyloid-β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double-strand breaks and glial activation. (B)...
febs.onlinelibrary.wiley.com
November 3, 2026 at 6:29 PM
Chaperone Hsp110 is essential for the integrity of the central nervous system. The #G3Journal cover shows the ubiquitous presence of Hsp110 chaperone (green) in a wild-type Drosophila larval brain co-stained with markers for glial (red – Repo) and neuronal (gray – Elav) cells.

1/2🧵⬇️
November 4, 2026 at 7:03 PM
¡El Instituto Clemente Estable celebra!

Investigadores e investigadoras de los departamentos de Neurofisiología Celular y Molecular y de Señalización Neuronal y Glial han publicado un estudio en la prestigiosa revista PNAS (Proceedings of the National Academy of Sciences).
November 3, 2026 at 8:38 PM
Goat Milk-derived Extracellular Vesicles modulate glial responses in vitro and attenuate neuroinflammation in vivo https://www.biorxiv.org/content/10.64898/2026.10.26.761897v1
October 30, 2026 at 10:19 PM
Blue light compromises cellular fate of intrinsically photosensitive Müller glial cells in the developing chicken retina. https://www.biorxiv.org/content/10.64898/2026.10.26.753828v1
October 30, 2026 at 10:19 PM
Goat Milk-derived Extracellular Vesicles modulate glial responses in vitro and attenuate neuroinflammation in vivo #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.26.761897v1
October 30, 2026 at 11:01 PM
I have a lot to say, but one simple take-home is that we found this because we asked where SID-1 functions in sRNA-mediated learned pathogen avoidance, and the ONLY place it's needed is in the amphid sheath glial cell! Totally counter to all worm dogma re. SID-1, AFAIK
October 28, 2026 at 4:49 PM
CSF1R inhibition during cranial radiotherapy reshapes the immune environment and glial dynamics #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11316756/latest
October 30, 2026 at 2:03 PM
Spatially resolved single-cell atlas reveals cortical glial reactivity associated with regions of neuronal growth programs in both hemispheres after stroke https://www.biorxiv.org/content/10.64898/2026.10.26.761917v1
October 30, 2026 at 10:19 PM