Maybe a lot of the 60s-70s epidemiology implicating fat was a blind alley, where most of the risk was due to smoking which greatly compounded the risk from hyperlipidaemia.
March 26, 2024 at 9:14 PM
Maybe a lot of the 60s-70s epidemiology implicating fat was a blind alley, where most of the risk was due to smoking which greatly compounded the risk from hyperlipidaemia.
New issue alert! 📢
- Articles in #maternalmedicine, #hypertension, #hyperlipidaemia, #heartfailure, #quadrupletherapy, #healthmessaging, #COVID19, #POCUS and more!
www.sciencedirect.com/journal/clin...
- Articles in #maternalmedicine, #hypertension, #hyperlipidaemia, #heartfailure, #quadrupletherapy, #healthmessaging, #COVID19, #POCUS and more!
www.sciencedirect.com/journal/clin...
April 17, 2025 at 1:21 PM
New issue alert! 📢
- Articles in #maternalmedicine, #hypertension, #hyperlipidaemia, #heartfailure, #quadrupletherapy, #healthmessaging, #COVID19, #POCUS and more!
www.sciencedirect.com/journal/clin...
- Articles in #maternalmedicine, #hypertension, #hyperlipidaemia, #heartfailure, #quadrupletherapy, #healthmessaging, #COVID19, #POCUS and more!
www.sciencedirect.com/journal/clin...
Then, suddenly, a googly is bowled
A bunch of possible risks are listed. BUT THE SOURCE IS NOT THE EVIDENCE REVIEWS.
Rather it is listed as "professional consensus exercise, July 2025". No details as to which professionals, how consensus was reached, etc. etc. etc.
A bunch of possible risks are listed. BUT THE SOURCE IS NOT THE EVIDENCE REVIEWS.
Rather it is listed as "professional consensus exercise, July 2025". No details as to which professionals, how consensus was reached, etc. etc. etc.
March 25, 2026 at 12:03 PM
Then, suddenly, a googly is bowled
A bunch of possible risks are listed. BUT THE SOURCE IS NOT THE EVIDENCE REVIEWS.
Rather it is listed as "professional consensus exercise, July 2025". No details as to which professionals, how consensus was reached, etc. etc. etc.
A bunch of possible risks are listed. BUT THE SOURCE IS NOT THE EVIDENCE REVIEWS.
Rather it is listed as "professional consensus exercise, July 2025". No details as to which professionals, how consensus was reached, etc. etc. etc.
Studies from Nikolaj Rittig & colleagues Pre-meal ketone supplementation reduced postprandial glucose, lipid and ghrelin concentrations #T2D link.springer.com/article/10.1... @diabetologiajnl.bsky.social 🧪
Ketone supplementation dose-dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study - Diabetologia
Aims/hypothesis Postprandial hyperglycaemia and hyperlipidaemia are independent risk factors for CVD in individuals with type 2 diabetes. We aimed to test whether a ketone monoester (KE) and ketone sa...
link.springer.com
November 30, 2025 at 11:38 AM
Studies from Nikolaj Rittig & colleagues Pre-meal ketone supplementation reduced postprandial glucose, lipid and ghrelin concentrations #T2D link.springer.com/article/10.1... @diabetologiajnl.bsky.social 🧪
Dementia Risk Profiles Unveiled: What you need to know in your 40's
A study on middle-aged adults found that most people had these 5 managable risk factors:
- hyperlipidaemia (92.5%)
- low cognitive activity (72.5%)
- obesity (57.6%)
- hypertension (52.7%)
1/2
A study on middle-aged adults found that most people had these 5 managable risk factors:
- hyperlipidaemia (92.5%)
- low cognitive activity (72.5%)
- obesity (57.6%)
- hypertension (52.7%)
1/2
November 20, 2025 at 10:15 PM
Dementia Risk Profiles Unveiled: What you need to know in your 40's
A study on middle-aged adults found that most people had these 5 managable risk factors:
- hyperlipidaemia (92.5%)
- low cognitive activity (72.5%)
- obesity (57.6%)
- hypertension (52.7%)
1/2
A study on middle-aged adults found that most people had these 5 managable risk factors:
- hyperlipidaemia (92.5%)
- low cognitive activity (72.5%)
- obesity (57.6%)
- hypertension (52.7%)
1/2
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
In type II diabetes (T2DM), the heart is exposed to hyperglycaemia, hyperlipidaemia, and hyperinsuli
www.biorxiv.org
November 21, 2024 at 5:17 AM
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
Coconut oil is a super food that is high in saturated fat so it isn't good for everyone! I can't have it because it will give me hyperlipidaemia lmao don't take health advice from influencers
September 27, 2023 at 8:13 AM
Coconut oil is a super food that is high in saturated fat so it isn't good for everyone! I can't have it because it will give me hyperlipidaemia lmao don't take health advice from influencers
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
In type II diabetes (T2DM), the heart is exposed to hyperglycaemia, hyperlipidaemia, and hyperinsuli
www.biorxiv.org
November 21, 2024 at 5:17 AM
Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. https://www.biorxiv.org/content/10.1101/2024.11.20.624467v1
Up front & free to read in our March issue #editorspicks: Ketone supplementation dose‑dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study doi.org/10.1007/s001...
Ketone supplementation dose-dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study - Diabetologia
Aims/hypothesis Postprandial hyperglycaemia and hyperlipidaemia are independent risk factors for CVD in individuals with type 2 diabetes. We aimed to test whether a ketone monoester (KE) and ketone sa...
doi.org
March 11, 2026 at 9:25 AM
Up front & free to read in our March issue #editorspicks: Ketone supplementation dose‑dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study doi.org/10.1007/s001...
6️⃣
💡 Modifiable Risk Factors (Part 2)
🍬 Diabetes: High sugar = faster atherosclerosis 🏗️ & small vessel damage.
🥑 Hyperlipidaemia: LDL ↑ plaques & narrowed arteries 🛑.
🚬 Smoking: Toxins damage vessels, ↑ clot risk.
💡 Modifiable Risk Factors (Part 2)
🍬 Diabetes: High sugar = faster atherosclerosis 🏗️ & small vessel damage.
🥑 Hyperlipidaemia: LDL ↑ plaques & narrowed arteries 🛑.
🚬 Smoking: Toxins damage vessels, ↑ clot risk.
February 20, 2025 at 7:00 AM
6️⃣
💡 Modifiable Risk Factors (Part 2)
🍬 Diabetes: High sugar = faster atherosclerosis 🏗️ & small vessel damage.
🥑 Hyperlipidaemia: LDL ↑ plaques & narrowed arteries 🛑.
🚬 Smoking: Toxins damage vessels, ↑ clot risk.
💡 Modifiable Risk Factors (Part 2)
🍬 Diabetes: High sugar = faster atherosclerosis 🏗️ & small vessel damage.
🥑 Hyperlipidaemia: LDL ↑ plaques & narrowed arteries 🛑.
🚬 Smoking: Toxins damage vessels, ↑ clot risk.
To what extent post-prandial does hyperlipidaemia impact systemic vascular function and dynamic cerebral autoregulation? Marley, Brugniaux, Tsukamoto, Bailey (University of South Wales) Joel Burma and Jonathan D. Smirl (@ucalgaryknes.bsky.social) share their findings.
📜 buff.ly/FkbjdeD
📜 buff.ly/FkbjdeD
October 29, 2025 at 11:15 AM
To what extent post-prandial does hyperlipidaemia impact systemic vascular function and dynamic cerebral autoregulation? Marley, Brugniaux, Tsukamoto, Bailey (University of South Wales) Joel Burma and Jonathan D. Smirl (@ucalgaryknes.bsky.social) share their findings.
📜 buff.ly/FkbjdeD
📜 buff.ly/FkbjdeD
When asked about what symptoms should worry you, all he said was palpitations. When asked about risk factors he got some right but mentioned smoking only Briefly, did not mention diabetes or hyperlipidaemia. Lord knows where they got him from.
February 22, 2026 at 6:20 PM
When asked about what symptoms should worry you, all he said was palpitations. When asked about risk factors he got some right but mentioned smoking only Briefly, did not mention diabetes or hyperlipidaemia. Lord knows where they got him from.
🏆 Congratulations to Christopher Marley et al., winners of our 2025 Best Paper Prize for their article 'Post-prandial hyperlipidaemia impairs systemic vascular function and dynamic cerebral autoregulation in young and old male adults'!
Read the paper 📖 buff.ly/b5osJdI
Read the paper 📖 buff.ly/b5osJdI
September 3, 2026 at 10:30 AM
🏆 Congratulations to Christopher Marley et al., winners of our 2025 Best Paper Prize for their article 'Post-prandial hyperlipidaemia impairs systemic vascular function and dynamic cerebral autoregulation in young and old male adults'!
Read the paper 📖 buff.ly/b5osJdI
Read the paper 📖 buff.ly/b5osJdI
Ketones lower postprandial glucose excursions! A comprehensive study tested different ketone supplements—salts and esters at varying doses. Result: lower postprandial glucose responses in people with #T2D vs placebo link.springer.com/article/10.1...
Ketone supplementation dose-dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study - Diabetologia
Aims/hypothesis Postprandial hyperglycaemia and hyperlipidaemia are independent risk factors for CVD in individuals with type 2 diabetes. We aimed to test whether a ketone monoester (KE) and ketone sa...
link.springer.com
December 11, 2025 at 1:38 PM
Ketones lower postprandial glucose excursions! A comprehensive study tested different ketone supplements—salts and esters at varying doses. Result: lower postprandial glucose responses in people with #T2D vs placebo link.springer.com/article/10.1...
From 👆 (2nd part)
December 5, 2024 at 9:50 PM
From 👆 (2nd part)
EFTA02458989.jpg
#epsteinweb #efta02458989
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta02458989
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
April 10, 2026 at 7:09 AM
EFTA02458989.jpg
#epsteinweb #efta02458989
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta02458989
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
Ⅱ型糖尿病または非糖尿病の高脂血症患者44名を対象に、ナイアシン 1,500mg を12週間で摂取させたところ、ナイアシンが脂質代謝改善効果および動脈硬化予防効果を持つことが示唆という研究。 pubmed.ncbi.nlm.nih.gov/7621303
Complementary effects of pravastatin and nicotinic acid in the treatment of combined hyperlipidaemia in diabetic and non-diabetic patients - PubMed
Pravastatin and nicotinic acid in lower-dose combination are more effective than pravastatin alone in reducing levels of triglyceride and elevating those of HDL cholesterol and are more effective than...
pubmed.ncbi.nlm.nih.gov
March 9, 2024 at 11:46 PM
Ⅱ型糖尿病または非糖尿病の高脂血症患者44名を対象に、ナイアシン 1,500mg を12週間で摂取させたところ、ナイアシンが脂質代謝改善効果および動脈硬化予防効果を持つことが示唆という研究。 pubmed.ncbi.nlm.nih.gov/7621303
3️⃣ 🧐 The Big Picture: Why Does This Happen?
The root cause? Atherosclerosis—a progressive buildup of fatty plaques inside arteries.
⚠️ Key Risk Factors:
🔹 Hypertension 🩸
🔹 Smoking 🚬
🔹 Diabetes 🍬
🔹 Hyperlipidaemia 🍔
🔹 Sedentary lifestyle 🛋️
🔹Social determinants !
Now for pathophysiology! ⬇️
The root cause? Atherosclerosis—a progressive buildup of fatty plaques inside arteries.
⚠️ Key Risk Factors:
🔹 Hypertension 🩸
🔹 Smoking 🚬
🔹 Diabetes 🍬
🔹 Hyperlipidaemia 🍔
🔹 Sedentary lifestyle 🛋️
🔹Social determinants !
Now for pathophysiology! ⬇️
February 26, 2025 at 6:37 AM
3️⃣ 🧐 The Big Picture: Why Does This Happen?
The root cause? Atherosclerosis—a progressive buildup of fatty plaques inside arteries.
⚠️ Key Risk Factors:
🔹 Hypertension 🩸
🔹 Smoking 🚬
🔹 Diabetes 🍬
🔹 Hyperlipidaemia 🍔
🔹 Sedentary lifestyle 🛋️
🔹Social determinants !
Now for pathophysiology! ⬇️
The root cause? Atherosclerosis—a progressive buildup of fatty plaques inside arteries.
⚠️ Key Risk Factors:
🔹 Hypertension 🩸
🔹 Smoking 🚬
🔹 Diabetes 🍬
🔹 Hyperlipidaemia 🍔
🔹 Sedentary lifestyle 🛋️
🔹Social determinants !
Now for pathophysiology! ⬇️
Såg den här nu. Faktorer relaterade till inflammation kanske leder till mer trasiga plack och tromboser.
I 70-talets Sverige och Norge kanske många hade kombinationen av förhöjt LDL *och* förhöjd inflammation (genom kroniska infektioner etc).
I 70-talets Sverige och Norge kanske många hade kombinationen av förhöjt LDL *och* förhöjd inflammation (genom kroniska infektioner etc).
Inflammatory and cholesterol risks and rates of major cardiovascular events among patients with atherosclerotic cardiovascular disease in routine care
AbstractAims. Inflammation and hyperlipidaemia play a pivotal role in atherosclerotic cardiovascular disease (ASCVD), and inflammatory risk may outweigh ch
doi.org
March 16, 2026 at 4:39 PM
Såg den här nu. Faktorer relaterade till inflammation kanske leder till mer trasiga plack och tromboser.
I 70-talets Sverige och Norge kanske många hade kombinationen av förhöjt LDL *och* förhöjd inflammation (genom kroniska infektioner etc).
I 70-talets Sverige och Norge kanske många hade kombinationen av förhöjt LDL *och* förhöjd inflammation (genom kroniska infektioner etc).
Identification and management of ocular lipid deposition in association with hyperlipidaemia in captive moray eels, Gymnothorax funebris Ranzani, Gymnothorax moringa (Cuvier) and Muraena retifera Goode and Bean. Journal of Fish Diseases, 35(9), 683-693
.
.
September 30, 2025 at 5:01 PM
Identification and management of ocular lipid deposition in association with hyperlipidaemia in captive moray eels, Gymnothorax funebris Ranzani, Gymnothorax moringa (Cuvier) and Muraena retifera Goode and Bean. Journal of Fish Diseases, 35(9), 683-693
.
.
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis - Nature
Early intermittent feeding of mice with a high-cholesterol Western-type diet accelerates atherosclerosis compared with late continuous exposure to the Western-type diet, despite similar cumulative cir...
www.nature.com
November 22, 2024 at 3:37 PM
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Open Access UCL Research: Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis discovery.ucl.ac.uk/id/eprint/10...
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis
-
UCL Discovery
UCL Discovery is UCL's open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
discovery.ucl.ac.uk
April 10, 2025 at 9:39 AM
Open Access UCL Research: Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis discovery.ucl.ac.uk/id/eprint/10...
It's licenced for hyperlipidaemia
Off patent thus inexpensive
Action is peroxisome proliferator-activated receptor (PPAR) agonism (2 other PPAR agonists were approved by the FDA last yr)
Like rifampicin, it can cause hepatitis. Like statins, muscle AEs incl myopathy (esp if concurrent renal imp)
Off patent thus inexpensive
Action is peroxisome proliferator-activated receptor (PPAR) agonism (2 other PPAR agonists were approved by the FDA last yr)
Like rifampicin, it can cause hepatitis. Like statins, muscle AEs incl myopathy (esp if concurrent renal imp)
February 19, 2025 at 7:35 AM
It's licenced for hyperlipidaemia
Off patent thus inexpensive
Action is peroxisome proliferator-activated receptor (PPAR) agonism (2 other PPAR agonists were approved by the FDA last yr)
Like rifampicin, it can cause hepatitis. Like statins, muscle AEs incl myopathy (esp if concurrent renal imp)
Off patent thus inexpensive
Action is peroxisome proliferator-activated receptor (PPAR) agonism (2 other PPAR agonists were approved by the FDA last yr)
Like rifampicin, it can cause hepatitis. Like statins, muscle AEs incl myopathy (esp if concurrent renal imp)
Isabgol Benefits: The Popular Gel-Like Remedy For Cholesterol, Know Side Effects
Isabgol Benefits: Blood cholesterol is a waxy fat-like substance that is produced by your liver or by animal-based foods that you consume. Experts suggest that cholesterol is not bad at all, unless you have too much…
Isabgol Benefits: Blood cholesterol is a waxy fat-like substance that is produced by your liver or by animal-based foods that you consume. Experts suggest that cholesterol is not bad at all, unless you have too much…
Isabgol Benefits: The Popular Gel-Like Remedy For Cholesterol, Know Side Effects
Isabgol Benefits: Blood cholesterol is a waxy fat-like substance that is produced by your liver or by animal-based foods that you consume. Experts suggest that cholesterol is not bad at all, unless you have too much of it. When your cholesterol is high, it means that you have too much fat in your blood. It is also known as high cholesterol or hyperlipidaemia.
news.presspost.in
November 24, 2025 at 10:03 AM
Isabgol Benefits: The Popular Gel-Like Remedy For Cholesterol, Know Side Effects
Isabgol Benefits: Blood cholesterol is a waxy fat-like substance that is produced by your liver or by animal-based foods that you consume. Experts suggest that cholesterol is not bad at all, unless you have too much…
Isabgol Benefits: Blood cholesterol is a waxy fat-like substance that is produced by your liver or by animal-based foods that you consume. Experts suggest that cholesterol is not bad at all, unless you have too much…