New online! Understanding the therapeutic toolkit for inflammatory bowel disease
Understanding the therapeutic toolkit for inflammatory bowel disease
Nature Reviews Gastroenterology & Hepatology, Published online: 31 January 2025; doi:10.1038/s41575-024-01035-7The management of inflammatory bowel disease (IBD) continues to evolve. This Review is a practical guide on the therapeutic toolkit for IBD,…
www.nature.com
February 1, 2025 at 5:41 PM
ICYMI: New online! Understanding the therapeutic toolkit for inflammatory bowel disease
Understanding the therapeutic toolkit for inflammatory bowel disease
Nature Reviews Gastroenterology & Hepatology, Published online: 31 January 2025; doi:10.1038/s41575-024-01035-7The management of inflammatory bowel disease (IBD) continues to evolve. This Review is a practical guide on the therapeutic toolkit for IBD,…
www.nature.com
February 15, 2025 at 8:25 AM
The immune system balances barrier defenses and systemic responses to maintain health. Diversity in antigen receptors enables pathogen recognition, but some epitopes are historically excluded due to biased selection. Cytokines polarize responses, influencing cell inclusion and immune status.
February 4, 2025 at 9:21 PM
November 16, 2024 at 5:12 PM
My #NIH grants fund understanding how gut immune cells get dysregulated before #IBD starts and how we can use the #microbiome prevent disease relapse without suppressing the immune system. #IBDsky #GIsky #Gastrosky
@sinaiimmuno.bsky.social @mountsinaigi.bsky.social
@sinaiimmuno.bsky.social @mountsinaigi.bsky.social
To help people understand the importance of NIH, share what you’ve used their funding for (in easily understandable terms).
I’ll start: my NIH postdoc funding helped me develop and test AI tools that could identify skin cancer across diverse skin tones.
I’ll start: my NIH postdoc funding helped me develop and test AI tools that could identify skin cancer across diverse skin tones.
January 29, 2025 at 1:09 AM
My #NIH grants fund understanding how gut immune cells get dysregulated before #IBD starts and how we can use the #microbiome prevent disease relapse without suppressing the immune system. #IBDsky #GIsky #Gastrosky
@sinaiimmuno.bsky.social @mountsinaigi.bsky.social
@sinaiimmuno.bsky.social @mountsinaigi.bsky.social
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
New online! The global burden of inflammatory bowel disease: from 2025 to 2045
The global burden of inflammatory bowel disease: from 2025 to 2045
Nature Reviews Gastroenterology & Hepatology, Published online: 18 July 2025; doi:10.1038/s41575-025-01097-1The global burden of inflammatory bowel disease (IBD) is shifting as countries transition through four epidemiologic stages. This Perspective explores the global evolution of IBD over the next 20 years and proposes strategies for prevention and health-care innovation.
www.nature.com
July 19, 2025 at 7:22 AM
Hi #GIsky! 👋 The #AGAGastroSquad is on #bsky and we're excited to connect with so many of you on a new platform! Come say hi and let your friends know we're here!
#GastroSky #LiverSky #IBDSky
#GastroSky #LiverSky #IBDSky
November 22, 2024 at 6:24 PM
Hi #GIsky! 👋 The #AGAGastroSquad is on #bsky and we're excited to connect with so many of you on a new platform! Come say hi and let your friends know we're here!
#GastroSky #LiverSky #IBDSky
#GastroSky #LiverSky #IBDSky
Greetings from the official Bluesky account of the UC Davis Division of GI & Hepatology!
We look forward to sharing our work and interacting with you all here!
#GIsky #Gastrosky #Liversky #IBDsky #Medsky
We look forward to sharing our work and interacting with you all here!
#GIsky #Gastrosky #Liversky #IBDsky #Medsky
November 24, 2024 at 2:38 AM
Greetings from the official Bluesky account of the UC Davis Division of GI & Hepatology!
We look forward to sharing our work and interacting with you all here!
#GIsky #Gastrosky #Liversky #IBDsky #Medsky
We look forward to sharing our work and interacting with you all here!
#GIsky #Gastrosky #Liversky #IBDsky #Medsky
New online! Shaping the future of inflammatory bowel disease: a global research agenda for better management and public health response
Shaping the future of inflammatory bowel disease: a global research agenda for better management and public health response
Nature Reviews Gastroenterology & Hepatology, Published online: 22 April 2025; doi:10.1038/s41575-025-01063-xInflammatory bowel disease (IBD) is an immune-mediated disease with substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts identify key priorities and recommendations to raise awareness and advance IBD care and research.
www.nature.com
April 23, 2025 at 7:38 PM
2025 guidelines for IBD from @amcollegegastro.bsky.social
Crohn's: journals.lww.com/ajg/fulltext...
UC: journals.lww.com/ajg/fulltext...
#IBDSky #MedSky #GISky
Crohn's: journals.lww.com/ajg/fulltext...
UC: journals.lww.com/ajg/fulltext...
#IBDSky #MedSky #GISky
June 21, 2025 at 12:21 AM
2025 guidelines for IBD from @amcollegegastro.bsky.social
Crohn's: journals.lww.com/ajg/fulltext...
UC: journals.lww.com/ajg/fulltext...
#IBDSky #MedSky #GISky
Crohn's: journals.lww.com/ajg/fulltext...
UC: journals.lww.com/ajg/fulltext...
#IBDSky #MedSky #GISky
New online! Influence of biological sex in inflammatory bowel diseases
Influence of biological sex in inflammatory bowel diseases
Nature Reviews Gastroenterology & Hepatology, Published online: 17 February 2025; doi:10.1038/s41575-025-01038-yBiological sex has a vital role in the pathogenesis of inflammatory bowel disease (IBD). This Review examines sex in IBD pathophysiology and…
www.nature.com
February 18, 2025 at 10:07 PM
Elevating this since there has been an influx of #GIsky, #Gastosky & #IBDsky folks over the last two weeks 💩
I'm working on a Starter Pack of #GIresearchers :) go.bsky.app/AHpSAzx
November 27, 2024 at 6:35 PM
New online! Early Crohn’s disease: can we change the disease course?
Early Crohn’s disease: can we change the disease course?
Nature Reviews Gastroenterology & Hepatology, Published online: 14 May 2025; doi:10.1038/s41575-025-01072-wCurrent treatments for Crohn’s disease prioritize early intervention with biological therapies, with several landmark trials demonstrating that starting biologic agents within the first years of diagnosis leads to superior patient outcomes. Although challenges remain, early use of biological treatments is increasingly supported in managing moderate to severe Crohn’s disease.
www.nature.com
May 15, 2025 at 8:01 AM
Our August issue is out now at www.thelancet.com/gastrohep!
Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…
#GastroSky #LiverSky #MedSky #IBDSky
Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…
#GastroSky #LiverSky #MedSky #IBDSky
July 10, 2025 at 5:21 AM
Our August issue is out now at www.thelancet.com/gastrohep!
Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…
#GastroSky #LiverSky #MedSky #IBDSky
Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…
#GastroSky #LiverSky #MedSky #IBDSky
#IBDSky: Highlight of the week!
Living guideline for moderate-to-severe ulcerative colitis
American Gastroenterological Association
@amergastroassn.bsky.social
#ulcerativecolitis #IBD #GastroSky
🔗 gastro.org/clinical-gui...
Living guideline for moderate-to-severe ulcerative colitis
American Gastroenterological Association
@amergastroassn.bsky.social
#ulcerativecolitis #IBD #GastroSky
🔗 gastro.org/clinical-gui...
November 26, 2024 at 9:23 PM
#IBDSky: Highlight of the week!
Living guideline for moderate-to-severe ulcerative colitis
American Gastroenterological Association
@amergastroassn.bsky.social
#ulcerativecolitis #IBD #GastroSky
🔗 gastro.org/clinical-gui...
Living guideline for moderate-to-severe ulcerative colitis
American Gastroenterological Association
@amergastroassn.bsky.social
#ulcerativecolitis #IBD #GastroSky
🔗 gastro.org/clinical-gui...
New - Hanna et al - Isolated perianal Crohn's disease: a systematic review and expert consensus proposing novel diagnostic criteria and management advice
www.thelancet.com/journals/lan...
#Gastrosky #Medsky #IBDSky
www.thelancet.com/journals/lan...
#Gastrosky #Medsky #IBDSky
April 30, 2025 at 5:21 AM
New - Hanna et al - Isolated perianal Crohn's disease: a systematic review and expert consensus proposing novel diagnostic criteria and management advice
www.thelancet.com/journals/lan...
#Gastrosky #Medsky #IBDSky
www.thelancet.com/journals/lan...
#Gastrosky #Medsky #IBDSky
It's #CCAwarenessWeek so don't forget to register for #CCCongress25! #IBDsky #GIsky #Gastrosky #GIresearchers
We join in making #IBDvisible for #CCAwarenessWeek. Register for #CCCongress25 today and learn the latest in #IBD research to make a difference for patients. #CCAW
📅 Feb. 6-8, 2025
📍 San Francisco, CA
https://buff.ly/4eYDbpO
📅 Feb. 6-8, 2025
📍 San Francisco, CA
https://buff.ly/4eYDbpO
December 3, 2024 at 8:11 PM
It's #CCAwarenessWeek so don't forget to register for #CCCongress25! #IBDsky #GIsky #Gastrosky #GIresearchers
Different properties of JAK inhibitors
--> different safety and efficacy profiles
- tofacitinib: JAK 1/3 inhibition
- upadacitinib & filgotinib: JAK 1 inhibition
#IBDSky
academic.oup.com/rheumatology...
--> different safety and efficacy profiles
- tofacitinib: JAK 1/3 inhibition
- upadacitinib & filgotinib: JAK 1 inhibition
#IBDSky
academic.oup.com/rheumatology...
November 24, 2024 at 2:12 PM
Different properties of JAK inhibitors
--> different safety and efficacy profiles
- tofacitinib: JAK 1/3 inhibition
- upadacitinib & filgotinib: JAK 1 inhibition
#IBDSky
academic.oup.com/rheumatology...
--> different safety and efficacy profiles
- tofacitinib: JAK 1/3 inhibition
- upadacitinib & filgotinib: JAK 1 inhibition
#IBDSky
academic.oup.com/rheumatology...
New Comment - Menopause and inflammatory bowel disease: more questions than answers
www.thelancet.com/journals/lan...
#GastroSky #MedSky #IBDSky
www.thelancet.com/journals/lan...
#GastroSky #MedSky #IBDSky
January 16, 2026 at 9:15 AM
New Comment - Menopause and inflammatory bowel disease: more questions than answers
www.thelancet.com/journals/lan...
#GastroSky #MedSky #IBDSky
www.thelancet.com/journals/lan...
#GastroSky #MedSky #IBDSky
Vedolizumab to prevent postoperative recurrence of Crohn's disease (the REPREVIO RCT)
"Vedolizumab prevented postoperative recurrence of CD & should be considered as a prophylactic treatment in individuals with risk factors for recurrence."
www.thelancet.com/journals/lan...
#GastroSky #IBDSky
"Vedolizumab prevented postoperative recurrence of CD & should be considered as a prophylactic treatment in individuals with risk factors for recurrence."
www.thelancet.com/journals/lan...
#GastroSky #IBDSky
November 19, 2024 at 4:58 AM
Vedolizumab to prevent postoperative recurrence of Crohn's disease (the REPREVIO RCT)
"Vedolizumab prevented postoperative recurrence of CD & should be considered as a prophylactic treatment in individuals with risk factors for recurrence."
www.thelancet.com/journals/lan...
#GastroSky #IBDSky
"Vedolizumab prevented postoperative recurrence of CD & should be considered as a prophylactic treatment in individuals with risk factors for recurrence."
www.thelancet.com/journals/lan...
#GastroSky #IBDSky
Periappendiceal red patch in ulcerative colitis
- aka caecal patch, appendiceal orifice inflammation
- a curious finding
- usually does not influence management
- does not mean that the disease is extensive
#IBDSky
- aka caecal patch, appendiceal orifice inflammation
- a curious finding
- usually does not influence management
- does not mean that the disease is extensive
#IBDSky
November 18, 2024 at 11:18 PM
Periappendiceal red patch in ulcerative colitis
- aka caecal patch, appendiceal orifice inflammation
- a curious finding
- usually does not influence management
- does not mean that the disease is extensive
#IBDSky
- aka caecal patch, appendiceal orifice inflammation
- a curious finding
- usually does not influence management
- does not mean that the disease is extensive
#IBDSky