#inhalational
Burns Inhalational Injury and Acute Respiratory Distress Syndrome

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
November 6, 2026 at 7:29 PM
#Greenhouse gas emissions focused #life cycle assessment by Lechani et al showing that #spinals have the lowest #carbon footprint followed by #TIVA and then #inhalational techniques for hysteroscopies.

https://www.sciencedirect.com/science/article/pii/S0007091226004873
November 6, 2026 at 11:00 PM
…→ End-Tidal Control Versus Manual Control of Inhalational Anesthesia Delivery: A Randomized Controlled Noninferiority Trial. Anesth. Analg. 2024 Oct 1; 139 (4): 812820812-820.

https://metajournal.com/articles/pm39028663 2/2
October 29, 2026 at 3:39 PM
Choice of general #anaesthetic for major #surgery can continue to be based on patient and clinician preference, according to the largest ever trial led by 🇬🇧 @uni-of-warwick.bsky.social comparing the two main techniques used in the NHS. Results are published in @jama.com.
Anaesthesia: TIVA or inhalation for major surgery?
Study results indicate that TIVA and inhalational anaesthesia are clinically and economically equivalent for adults having major non-cardiac surgery
healthcare-in-europe.com
October 26, 2026 at 7:36 AM
'Recent experimental evidence, briefly reviewed here, points to intraneuronal microtubules as a functional target of inhalational anesthetics. This finding is consistent with the general hypothesis that the biophysical substrate of consciousness is a collective quantum
state of microtubules.'
October 17, 2026 at 4:08 PM
methoxyflurane (Penthrox) is classified as an inhalational anesthetic, but when used in the green whistle, it is given at a low dose specifically for analgesic (pain relief) effects.
October 14, 2026 at 8:44 AM
"Similar to other inhalational anesthetics, the exact mechanism of action is not clearly defined and likely involves multiple molecular targets in the brain and spinal cord. Methoxyflurane is a
October 13, 2026 at 11:47 PM
…→ Environmental and economic impact of using increased fresh gas flow to reduce carbon dioxide absorbent consumption in the absence of inhalational anaesthetics. Br J Anaesth. 2020 Nov 1; 125 (5): 773778773-778.

https://metajournal.com/articles/pm32859360 2/2
September 29, 2026 at 8:37 AM
Open Access UCL Research: Total Intravenous vs Volatile Inhalational Anesthesia for Major Noncardiac Surgery : A Randomized Clinical Trial discovery.ucl.ac.uk/id/eprint/10...
September 14, 2026 at 10:11 AM
Yes, think the choice of anaesthetic makes no difference on 'hard' outcomes. Backed up by www.thelancet.com/journals/ecl... from 2024.

Consistently better on the 'soft' measures like patient experience though, which is why I do it.
Mortality and morbidity after total intravenous anaesthesia versus inhalational anaesthesia: a systematic review and meta-analysis
The results indicate that postoperative mortality and organ-related morbidity was similar for intravenous and inhalational anaesthesia. Total intravenous anaesthesia offered advantages in postoperativ...
www.thelancet.com
September 2, 2026 at 9:20 AM
Yeah, it's very funny. I also find it funny when people act like it's a massive faff as though most of the function of the anaesthetic machine isn't too facilitate inhalational anaesthesia.

You could replace it with a transfer vent if you do TIVA.
September 2, 2026 at 4:51 AM
I mean, I mostly do TIVA to annoy my colleagues who prefer using inhalational but I'm quite close to switching to inhalational to annoy my colleagues who do TIVA.

Or something evidence-based for my decision.
September 1, 2026 at 8:28 PM
Xenon is the ideal inhalational anaesthetic agent apparently. Except it's bloody expensive
August 22, 2026 at 8:31 PM
“Several transmission events were considered consistent with inhalational exposure, and the investigators concluded that transmission may have occurred through “inhalation of droplets or aerosolized virions.”
May 13, 2026 at 6:55 AM
Pieter do you routinely draw up emergency drugs for paediatric inhalational inductions?
July 12, 2025 at 9:36 PM
I don’t routinely offer a choice though. 🤔

If I ran into unanticipated problems wout IV access in someone w no particular aversion to having it established awake (who’d only had an inhalational induction bc I’d offered it as an equally safe alternative), I’d find that difficult to defend.
June 21, 2025 at 5:05 PM
Yeah, I do inhalational inductions if they don’t want a needle (provided no airway issues) just not ‘single breath’. I can’t remember the last time I had an adult patient who was significantly concerned about a needle though.
June 21, 2025 at 5:05 PM
I can’t remember the last time I saw an adult with any significant needle phobia. It would seriously be > 10 yrs since I’ve needed to do an inhalational induction for that purpose. And it used to happen regularly. It must be the 29G insulin syringe w local. 🤷🏻‍♂️
June 21, 2025 at 1:14 PM
Even w inhalational induction ALWAYS get IV access (& give some propofol) before instrumenting airway.

Purpose of gas induction is to achieve unconsciousness, not to secure the airway.
June 20, 2025 at 11:03 PM
Inhalational induction (in appropriate patients) is useful but single breath induction is an anaesthetic parlour trick. Again it’s more about anaesthetic showmanship than patient care.
June 20, 2025 at 11:01 PM
Unsurprisingly @chrimesy.com has an opinion on this… 😂
The central point is if you consider it a ‘core skill’.

Here’s our description of a core skill and why AFOI doesn’t meet that standard.

#AnSky

associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/...
July 2, 2025 at 5:25 AM
Essentially no des in the last 6 yr (& less iso) & nitrous only used to facilitate some inhalational induction #ansky
January 17, 2026 at 8:19 AM
No evidence nitrous improves inhalational induction And we’ve data saying it doesn’t reduce sevo used
August 14, 2025 at 9:53 AM