#leptin
⚡Leptin - Die Energieanzeige

Leptin wird vom Fettgewebe ausgeschüttet und zwar nicht durch eine Mahlzeit, sondern abhängig von unseren Energiereserven.

Dabei gilt:

Mehr Fett = Mehr Leptin

Hohe Leptinwerte zeigen unserem Körper: wir haben genug Energie gespeichert. Senkt den Appetit langfristig.
July 3, 2025 at 8:34 AM
doi.org/10.1038/s415... And also from the #JeffFriedman lab. At last, a neuronal population that is activated by leptin and (unlike the POMC neuron) rapidly suppreses feeding
Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake - Nature
We find that leptin-target neurons expressing basonuclin 2 in the arcuate nucleus that acutely suppress appetite by directly inhibiting agouti-related protein neurons are a key component of the neural...
doi.org
December 7, 2024 at 4:25 PM
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
July 15, 2025 at 2:12 PM
On the psychological side there’s you know, the whole food focused world we live in, and how many people have disordered eating related to emotional issues but on top of that when you lose weight your brain fucks with your reward system and the way leptin works basically begs you to binge
September 24, 2026 at 9:47 AM
Plasma-Leptin und BMI wirkten als positive Mediatoren. Sie könnten ein Teil des biologischen Mechanismus sein, über den Infektionen zu Frailty beitragen. Die identifizierte Mediationsrolle von BMI und Leptin deutet auf einen Zusammenhang zwischen Infektionen, metabolischer
March 2, 2026 at 8:16 PM
I don't think scientists should work for anyone else. They should work for discovery and for their own curiosity.
– Maria Leptin, ERC President @marialep.bsky.social
(From the episode of the Night Science Podcast coming out next week @nightsciencepod.bsky.social )
December 1, 2025 at 2:21 AM
The number of grant applications is rising sharply. Our capacity for their evaluation isn’t.

ERC President Maria Leptin explains why stricter resubmission limits are being introduced for 2027 calls and what they mean for applicants.

🔗 link.europa.eu/xF7kjc
ERC President explains stricter application measures amid rising demand for funding
The text of an open letter sent by ERC President Maria Leptin to ERC panel members, grantees and other stakeholders on 16 April 2026.
link.europa.eu
April 17, 2026 at 8:48 AM
Here the authors further support the link between #leptin signaling and tissue #fibrosis demonstrating that a leptin-neutralizing antibody may be a promising therapeutic approach for reducing fibrosis in the kidney, liver, lung, heart, and blood vessels www.science.org/doi/10.1126/...
Leptin as a key driver for organ fibrogenesis
Neutralizing leptin reduces inflammation and fibrosis in mice, suggesting a potential treatment for fibrotic diseases.
www.science.org
October 22, 2025 at 6:11 PM
President of the @erc.europa.eu, Prof Maria Leptin, delivering the keynote address at an European Research Council Impact Forum hosted by Research Ireland in Dublin today. Prof. Leptin is on a visit to Dublin for a series of engagements with research and political leaders.

(Photo: Finbarr O'Rourke)
April 1, 2025 at 1:07 PM
Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table!
www.science.org/doi/10.1126/...
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.
www.science.org
December 4, 2024 at 8:27 PM
There’s an art to writing a grant proposal so that your creativity is on full display. Maria Leptin - president of the ERC - talks about it on the new episode of the Night Science Podcast.
December 9, 2025 at 4:36 AM
I don't think scientists should work for anyone else. They should work for discovery and for their own curiosity.
–Maria Leptin, ERC President @marialep.bsky.social on 'The Night Science Podcast'
December 10, 2025 at 4:08 AM
Maria Leptin: Postulat 3 proc. PKB na naukę to nie jest radykalne żądanie. Więcej: wyborcza.pl/7,75398,3282...
May 31, 2026 at 6:45 AM
Some memories of last week's Dublin visit of President of the European Research Council @erc.europa.eu, Prof Maria Leptin @marialep.bsky.social

The keynote speaker at an ERC Impact Forum hosted by Research Ireland, Prof. Leptin also held a series of engagements with research and political leaders.
April 7, 2025 at 1:34 PM
Seeking a PhD at Cambridge in collaboration with NovoNordisk?

Consider this funded opportunity titled "Human cellular models of leptin signalling and resistance": bbsrcdtp.lifesci.cam.ac.uk/project-refe...

Application details: bbsrcdtp.lifesci.cam.ac.uk/how-apply

Thanks for spreading the word!
September 22, 2026 at 6:35 PM
ERC President Maria Leptin told @politico.eu the body wants to maintain “Europe’s tradition of openness and support for independent, investigator-driven research, regardless of the nationality or the current location of grant applicants.” Leptin insisted the ERC isn't purposely
April 4, 2025 at 12:07 PM
The Maria Leptin | EMBO Science Journalism Fellowships support life scientists pursuing a career in #ScienceJournalism and science journalists who wish to further their scientific education.

Apply now: buff.ly/2YPDOJv
#LifeSciences #Funding 🧪
Fellowships, grants and career support – Maria Leptin | EMBO Science Journalism Fellowships – EMBO
Supporting life scientists pursuing a career in science journalism and science journalists who wish to further their scientific education
buff.ly
May 14, 2025 at 5:47 AM
What are the genetic origins of early-onset #obesity?

Studying a cohort of young adults in China, researchers in #ScienceTranslationalMedicine performed deep sequencing and identified a loss-of-function variant in the gene TUB that impairs sensitivity to leptin. https://scim.ag/4rg1Qxl
The TUB variant impairs leptin sensitivity and AgRP neuronal response, leading to obesity
Rare human TUB variants impair leptin sensitivity through disruption of STAT3 activation, leading to hyperphagic obesity.
scim.ag
February 12, 2026 at 4:00 PM
Where is all the love for hormones that aren’t sex hormones, huh? Thyroid Stimulating Hormone. That’s a good one. Anybody got any TSH jokes? Anyone? How bout that insulin guys? Leptin, ghrelin? No? I just started levothyroxine, does any body find that relatable or cool?
March 18, 2024 at 3:01 AM
🌟 We were honoured to welcome @erc.europa.eu president Maria Leptin to CSH! Helga Nowotny, chair of CSH science board, and Stefan Thurner, CSH president, met with her. Leptin also connected with Mirta Galesic (ERC Advanced Grant) and Aashima Dogra (Maria Leptin @embo.org Fellow).
September 12, 2025 at 7:02 AM
This demon is called leptin resistance in my house
I literally feel like i have extreme hunger. Like i need to eat or i will die instantly i cant stop thinking bout food and eating it my stomach is a hole so dramatic like im dying
February 24, 2025 at 5:28 PM
Maria Leptin re-appointed as ERC President! 🇪🇺

ERC Vice Presidents said:

This is excellent news, ensuring continuity at a critical moment. On behalf of the Scientific Council, we thank Maria for her leadership & strong commitment that has taken ERC to new heights.

👇
erc.europa.eu/news-events/...
October 1, 2025 at 5:47 PM