An overview of the regulatory role of #m6Amodification in #BoneFormation & #StemCell directional differentiation, its pathological role & underlying mechanisms in #BoneDiseases, and m6A targeting therapeutic strategies.

#OpenAccess: doi.org/10.1016/j.ge...

KIAA1429 is highly expressed in #ChronicMyeloidLeukemia (CML) blast crisis (BC) and enhances RAB27B mRNA stability, upregulating its expression through the KIAA1429/m6A/YTHDF1 axis, , ultimately driving CML progression. #m6AModification #medsky

📝Online now - the Review "Reciprocal regulation of m6A and noncoding RNAs across kingdoms" from Bochen Jiang, Xiaoming Zhang, et al.

#epitranscriptomics #m6AModification #noncodingRNA #lncRNA #circRNA #miRNA

Read it here: authors.elsevier.com/a/1mrsu3S6Gf...

Most read on #m6Amethylation!
This review summarizes research advances in RNA #m6Amodification and its function in #ncRNAs, while also discussing the potential #therapeuticstrategies to target RNA m6A regulators for disease therapy. #medsky
#OpenAccess:

This review summarizes research advances in RNA #m6Amodification and its function in #ncRNAs, while also discussing the potential therapeutic strategies to target RNA m6A regulators for disease therapy. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

N6-Methyladenosine (m6A) Reader LRPPRC-Mediated CXCL11 Induces Cell Inflammation to Drive Breast Cancer Cell Malignancy

www.dl.begellhouse.com/journals/2ff...

#m6AModification #BreastCancer #TumorInflammation

KIAA1429 is highly expressed in #ChronicMyeloidLeukemia (CML) blast crisis (BC) and enhances RAB27B mRNA stability, upregulating its expression through the KIAA1429/m6A/YTHDF1 axis, ultimately driving CML progression. #m6AModification #medsky
#OpenAccess:
buff.ly/H5PEexz

This review explores the latest developments in understanding #m6AModification and its potential role in modulating #CellFate transition and pluripotent states of mouse and human #EmbryonicStemCells. #Epigenetics #medsky

#OpenAccess: www.sciencedirect.co...