What controls the balance between #cartilage and #BoneFormation?
ST3GAL1-associated α-2,3 sialylation regulates chondrocyte and #osteoblast differentiation, with its loss impairing growth plate maturation & reducing bone mass.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
ST3GAL1-associated α-2,3 sialylation regulates chondrocyte and #osteoblast differentiation, with its loss impairing growth plate maturation & reducing bone mass.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
September 29, 2026 at 12:30 AM
What controls the balance between #cartilage and #BoneFormation?
ST3GAL1-associated α-2,3 sialylation regulates chondrocyte and #osteoblast differentiation, with its loss impairing growth plate maturation & reducing bone mass.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
ST3GAL1-associated α-2,3 sialylation regulates chondrocyte and #osteoblast differentiation, with its loss impairing growth plate maturation & reducing bone mass.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
Latest Advances in Structural Insights and Quantification Techniques for Type I Collagen Biomarkers: A path toward standardization?
@journals.sagepub.com @biomarkerinsights.bsky.social
journals.sagepub.com/doi/10.1177/...
#bonemarker #boneturnover #boneformation #medicine #medsky #openaccess
@journals.sagepub.com @biomarkerinsights.bsky.social
journals.sagepub.com/doi/10.1177/...
#bonemarker #boneturnover #boneformation #medicine #medsky #openaccess
May 29, 2025 at 10:09 PM
Latest Advances in Structural Insights and Quantification Techniques for Type I Collagen Biomarkers: A path toward standardization?
@journals.sagepub.com @biomarkerinsights.bsky.social
journals.sagepub.com/doi/10.1177/...
#bonemarker #boneturnover #boneformation #medicine #medsky #openaccess
@journals.sagepub.com @biomarkerinsights.bsky.social
journals.sagepub.com/doi/10.1177/...
#bonemarker #boneturnover #boneformation #medicine #medsky #openaccess
An overview of the regulatory role of #m6Amodification in #BoneFormation & #StemCell directional differentiation, its pathological role & underlying mechanisms in #BoneDiseases, and m6A targeting therapeutic strategies.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
December 13, 2025 at 4:11 PM
An overview of the regulatory role of #m6Amodification in #BoneFormation & #StemCell directional differentiation, its pathological role & underlying mechanisms in #BoneDiseases, and m6A targeting therapeutic strategies.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
MSDC-0602K, a next-generation #TZD, rewires metabolism in bone marrow stem cells - promoting #BoneFormation while reducing #BMAT accumulation. This tissue-specific approach opens new doors for safer #Diabetes treatments! The paper is archived at bma-society.org/paper-of-the...
Paper of the Month Archive - (BMAS)
Past issues of the Paper of the Month selected by the Scientific Board of the Bone Marrow Adiposity Society
bma-society.org
June 20, 2025 at 6:45 PM
MSDC-0602K, a next-generation #TZD, rewires metabolism in bone marrow stem cells - promoting #BoneFormation while reducing #BMAT accumulation. This tissue-specific approach opens new doors for safer #Diabetes treatments! The paper is archived at bma-society.org/paper-of-the...
Watch the ZDF Moma Future report where Berna Özkale Edelmann and Chen Wang explain how laser-controlled #nanorobots mechanically stimulate #stemcells and support #boneformation (in German): go.tum.de/350963
#microrobotics
📷ZDF
#microrobotics
📷ZDF
Nanorobots on ZDF moma future
How stem cells are transformed into bone cells with the help of nanorobots.
go.tum.de
April 22, 2026 at 11:55 AM
Watch the ZDF Moma Future report where Berna Özkale Edelmann and Chen Wang explain how laser-controlled #nanorobots mechanically stimulate #stemcells and support #boneformation (in German): go.tum.de/350963
#microrobotics
📷ZDF
#microrobotics
📷ZDF
#osteoporosis #UCB #romosozumab #clinicalstudies #bonemineraldensity #osteoporosistreatment #osteoporosistreatment #boneformation #boneresorption #WCOIOFESCEO2025 #systematicliteraturereview #realworldevidence #severeosteoporosis #osteoporosismanagement
pharmatimes.com/news/global-...
pharmatimes.com/news/global-...
Global data highlights effectiveness of romosozumab - PharmaTimes
Studies show improved bone mineral density and healthcare cost reductions
pharmatimes.com
April 16, 2025 at 11:00 AM
Insights into how adhesion G protein-coupled receptor 133 contributes to #BoneFormation through local cell-cell interactions between osteoblasts and osteoclasts, making it a promising candidate for treating osteopenic conditions.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
November 6, 2025 at 8:15 AM
Insights into how adhesion G protein-coupled receptor 133 contributes to #BoneFormation through local cell-cell interactions between osteoblasts and osteoclasts, making it a promising candidate for treating osteopenic conditions.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
The #mechanosensitive channel #Piezo1 in #BMMSCs suppresses #BoneMarrow #adipogenesis and promotes #BoneFormation by blocking the Ccl2–Lcn2 inflammatory loop, linking #mechanotransduction to #inflammation control and bone strength.
#OpenAccess in #STTT: doi.org/10.1038/s413...
#OpenAccess in #STTT: doi.org/10.1038/s413...
November 1, 2025 at 1:05 AM
The #mechanosensitive channel #Piezo1 in #BMMSCs suppresses #BoneMarrow #adipogenesis and promotes #BoneFormation by blocking the Ccl2–Lcn2 inflammatory loop, linking #mechanotransduction to #inflammation control and bone strength.
#OpenAccess in #STTT: doi.org/10.1038/s413...
#OpenAccess in #STTT: doi.org/10.1038/s413...
SIRT5 enhances BMP9 osteo-inductive potential by stabilizing HIF-1α in mouse embryonic fibroblasts.
#SIRT5 #BMP9 #HIF1alpha #OsteogenicDifferentiation #BoneFormation #StemCellBiology
www.sciencedirect.com/science/arti...
#SIRT5 #BMP9 #HIF1alpha #OsteogenicDifferentiation #BoneFormation #StemCellBiology
www.sciencedirect.com/science/arti...
April 7, 2026 at 8:04 PM
SIRT5 enhances BMP9 osteo-inductive potential by stabilizing HIF-1α in mouse embryonic fibroblasts.
#SIRT5 #BMP9 #HIF1alpha #OsteogenicDifferentiation #BoneFormation #StemCellBiology
www.sciencedirect.com/science/arti...
#SIRT5 #BMP9 #HIF1alpha #OsteogenicDifferentiation #BoneFormation #StemCellBiology
www.sciencedirect.com/science/arti...
#APPswe enhances BMP2-induced #osteogenesis in #MSCs via its intracellular domain by inhibiting #NotchSignaling, while limiting proliferation and migration, revealing a dual role in #BoneFormation and stem cell maintenance.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 1, 2026 at 6:15 PM
#APPswe enhances BMP2-induced #osteogenesis in #MSCs via its intracellular domain by inhibiting #NotchSignaling, while limiting proliferation and migration, revealing a dual role in #BoneFormation and stem cell maintenance.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
By attenuating #ERstress and chondrocyte #Apoptosis, melatonin mitigates Slc26a2-associated #Chondrodysplasias, promoting #Chondrocyte survival, partially alleviating growth retardation, and improving trabecular #BoneFormation. #medsky
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
January 10, 2026 at 2:35 PM
By attenuating #ERstress and chondrocyte #Apoptosis, melatonin mitigates Slc26a2-associated #Chondrodysplasias, promoting #Chondrocyte survival, partially alleviating growth retardation, and improving trabecular #BoneFormation. #medsky
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...