E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 9:16 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 10:25 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 10:17 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 6:05 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 8:27 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
October 11, 2026 at 7:07 AM
E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist - Cambridge Job educativ.net/jobs/job/66739...
Sometimes the test exists to keep you out. Gleevec is approved for aggressive systemic mastocytosis only in adults without the D816V c-Kit mutation, or whose mutation status is unknown. (4/8)
October 7, 2026 at 1:01 PM
Sometimes the test exists to keep you out. Gleevec is approved for aggressive systemic mastocytosis only in adults without the D816V c-Kit mutation, or whose mutation status is unknown. (4/8)
📃Scientific paper: The influence of nutritional habits, body mass index and intestinal microbiota in mastocytosis on clinical symptoms using conventional culture and next generation sequencing
Ref.: John Wiley and Sons Inc., 2024
➡️ Continued on ES/IODE
Ref.: John Wiley and Sons Inc., 2024
➡️ Continued on ES/IODE
October 6, 2026 at 5:02 PM
📃Scientific paper: The influence of nutritional habits, body mass index and intestinal microbiota in mastocytosis on clinical symptoms using conventional culture and next generation sequencing
Ref.: John Wiley and Sons Inc., 2024
➡️ Continued on ES/IODE
Ref.: John Wiley and Sons Inc., 2024
➡️ Continued on ES/IODE
📢 New Case Report in #LiversMDPI
🧬 Cook et al. present a 60-year-old man diagnosed with ASM after bone marrow and liver biopsies confirmed mast cell infiltration
🩺 The patient developed noncirrhotic portal hypertension
📖 Read More: www.mdpi.com/2673-4389/6/...
#Mastocytosis #LiverDisease
🧬 Cook et al. present a 60-year-old man diagnosed with ASM after bone marrow and liver biopsies confirmed mast cell infiltration
🩺 The patient developed noncirrhotic portal hypertension
📖 Read More: www.mdpi.com/2673-4389/6/...
#Mastocytosis #LiverDisease
October 5, 2026 at 11:05 AM
📢 New Case Report in #LiversMDPI
🧬 Cook et al. present a 60-year-old man diagnosed with ASM after bone marrow and liver biopsies confirmed mast cell infiltration
🩺 The patient developed noncirrhotic portal hypertension
📖 Read More: www.mdpi.com/2673-4389/6/...
#Mastocytosis #LiverDisease
🧬 Cook et al. present a 60-year-old man diagnosed with ASM after bone marrow and liver biopsies confirmed mast cell infiltration
🩺 The patient developed noncirrhotic portal hypertension
📖 Read More: www.mdpi.com/2673-4389/6/...
#Mastocytosis #LiverDisease
The *absolute* earliest work identifying it as separate from systemic mastocytosis is 2006 (Molderings), 2007 (Molderings), and 2010 (Afrin), and there wasn't even a first attempt at diagnostic criteria until 2011 (pubmed.ncbi.nlm.nih.gov/21418662/)
Checking your browser - reCAPTCHA
pubmed.ncbi.nlm.nih.gov
September 29, 2026 at 3:48 PM
The *absolute* earliest work identifying it as separate from systemic mastocytosis is 2006 (Molderings), 2007 (Molderings), and 2010 (Afrin), and there wasn't even a first attempt at diagnostic criteria until 2011 (pubmed.ncbi.nlm.nih.gov/21418662/)
Serum tryptase is only elevated with MCAS (as opposed to systemic mastocytosis) for 2 hours tops after an exposure! You can get a more accurate sense with a 24 hour urine collection tryptase test, but that one is so incredibly temperature-sensitive that you can invalidate it--
September 29, 2026 at 3:38 PM
Serum tryptase is only elevated with MCAS (as opposed to systemic mastocytosis) for 2 hours tops after an exposure! You can get a more accurate sense with a 24 hour urine collection tryptase test, but that one is so incredibly temperature-sensitive that you can invalidate it--
I’m 33, I’ve had shingles twice, am diagnosed with MCAS (bone marrow biopsy to rule out mastocytosis & 24 hours inpatient to confirm idiopathic anaphylaxis) which requires immunosuppressive meds. But I can’t find a doctor to prescribe me the shingles vaccine - why are are they so strict on being 50?
September 26, 2026 at 12:17 PM
I’m 33, I’ve had shingles twice, am diagnosed with MCAS (bone marrow biopsy to rule out mastocytosis & 24 hours inpatient to confirm idiopathic anaphylaxis) which requires immunosuppressive meds. But I can’t find a doctor to prescribe me the shingles vaccine - why are are they so strict on being 50?
Movie of the night: Escape Room (2019).
I keep thinking my body can't surprise me further. CRPS, dystonia/myoclonus, POTS and mastocytosis cluster flare. Like wtf next 😃
I keep thinking my body can't surprise me further. CRPS, dystonia/myoclonus, POTS and mastocytosis cluster flare. Like wtf next 😃
September 27, 2026 at 7:18 AM
Movie of the night: Escape Room (2019).
I keep thinking my body can't surprise me further. CRPS, dystonia/myoclonus, POTS and mastocytosis cluster flare. Like wtf next 😃
I keep thinking my body can't surprise me further. CRPS, dystonia/myoclonus, POTS and mastocytosis cluster flare. Like wtf next 😃
Ready for the massive controversy 15 years from now over Mastocytosis isn’t real.
This can be prevented by everyone getting over themselves now and admitting Long Covid is real
This can be prevented by everyone getting over themselves now and admitting Long Covid is real
September 25, 2026 at 5:57 AM
Ready for the massive controversy 15 years from now over Mastocytosis isn’t real.
This can be prevented by everyone getting over themselves now and admitting Long Covid is real
This can be prevented by everyone getting over themselves now and admitting Long Covid is real
Thanks! I got tested for MCAS and it was neg, though I heard maybe those tests aren't reliable? It doesn't look like the pics of cutaneous mastocytosis tho.
September 24, 2026 at 12:04 AM
Thanks! I got tested for MCAS and it was neg, though I heard maybe those tests aren't reliable? It doesn't look like the pics of cutaneous mastocytosis tho.
Have you discussed with your doctors about potential cutaneous mastocytosis? Or mast cell activation syndrome? Mastocytes are immune cells, causing allergic-like reactions (not though IgE or IgA though) and known to be sensitive to emotions, among other things.
September 23, 2026 at 9:48 PM
Have you discussed with your doctors about potential cutaneous mastocytosis? Or mast cell activation syndrome? Mastocytes are immune cells, causing allergic-like reactions (not though IgE or IgA though) and known to be sensitive to emotions, among other things.
💥 @fda.gov has accepted an NDA for bezuclastinib for the treatment of patients with advanced systemic mastocytosis, supported by phase 2 trial data.
Full details ➡️: onclive.com/view/fda-acc...
#oncology #hematology
Full details ➡️: onclive.com/view/fda-acc...
#oncology #hematology
FDA Accepts NDA for Bezuclastinib in Advanced Systemic Mastocytosis | OncLive
The FDA set a target action date of June 29, 2027, for bezuclastinib's NDA in advanced systemic mastocytosis, backed by APEX trial data.
onclive.com
September 15, 2026 at 6:40 PM
💥 @fda.gov has accepted an NDA for bezuclastinib for the treatment of patients with advanced systemic mastocytosis, supported by phase 2 trial data.
Full details ➡️: onclive.com/view/fda-acc...
#oncology #hematology
Full details ➡️: onclive.com/view/fda-acc...
#oncology #hematology
“The lovely summer we’ve had here this year” says a travel businesswoman on the radio just now. Lovely?! Try it with systemic mastocytosis, my friend.
September 14, 2026 at 11:47 AM
“The lovely summer we’ve had here this year” says a travel businesswoman on the radio just now. Lovely?! Try it with systemic mastocytosis, my friend.
Dr. Aram Bidikian and Yale colleagues share a case report in Leukemia & Lymphoma @tandfonline.bsky.social on the reversal of systemic mastocytosis-induced liver #cirrhosis with #avapritinib treatment.
tandfonline.com/doi/full/10....
@yale-hematology.bsky.social @yalepathology.bsky.social
tandfonline.com/doi/full/10....
@yale-hematology.bsky.social @yalepathology.bsky.social
Reversal of systemic mastocytosis-induced liver cirrhosis with avapritinib treatment: case report
Published in Leukemia & Lymphoma (Ahead of Print, 2026)
tandfonline.com
September 9, 2026 at 12:04 PM
Dr. Aram Bidikian and Yale colleagues share a case report in Leukemia & Lymphoma @tandfonline.bsky.social on the reversal of systemic mastocytosis-induced liver #cirrhosis with #avapritinib treatment.
tandfonline.com/doi/full/10....
@yale-hematology.bsky.social @yalepathology.bsky.social
tandfonline.com/doi/full/10....
@yale-hematology.bsky.social @yalepathology.bsky.social
In systemic mastocytosis, an excess of mast cells, which normally drive allergic reactions and fight parasites, release high levels of chemicals that affect blood flow and trigger inflammation.
September 8, 2026 at 11:15 PM
In systemic mastocytosis, an excess of mast cells, which normally drive allergic reactions and fight parasites, release high levels of chemicals that affect blood flow and trigger inflammation.
Mengapa Tubuh Ini Melepaskan 'Bom Histamin' Setiap Kali Dia Sentuh Daun Pokok?
Di sebuah kampung kecil di Jerman pada tahun 1930-an, seorang remaja jatuh pingsan selepas menyentuh daun pokok ceri — bukan kerana alahan biasa, tetapi kerana sel-sel pertahananny
Di sebuah kampung kecil di Jerman pada tahun 1930-an, seorang remaja jatuh pingsan selepas menyentuh daun pokok ceri — bukan kerana alahan biasa, tetapi kerana sel-sel pertahananny
Mengapa Tubuh Ini Melepaskan 'Bom Histamin' Setiap Kali Dia Sentuh Daun Pokok?
Di sebuah kampung kecil di Jerman pada tahun 1930-an, seorang remaja jatuh pingsan selepas menyentuh daun pokok ceri — bukan kerana alahan biasa, tetapi kerana sel-sel pertahanannya sendiri telah berubah menjadi 'penghancur dalam'. Inilah mula-mula mastocytosis direkod dalam sejarah perubatan dunia:
khatulistiwa.org
September 2, 2026 at 11:57 AM
Mengapa Tubuh Ini Melepaskan 'Bom Histamin' Setiap Kali Dia Sentuh Daun Pokok?
Di sebuah kampung kecil di Jerman pada tahun 1930-an, seorang remaja jatuh pingsan selepas menyentuh daun pokok ceri — bukan kerana alahan biasa, tetapi kerana sel-sel pertahananny
Di sebuah kampung kecil di Jerman pada tahun 1930-an, seorang remaja jatuh pingsan selepas menyentuh daun pokok ceri — bukan kerana alahan biasa, tetapi kerana sel-sel pertahananny
Sometimes the test exists to keep you out. Gleevec is approved for aggressive systemic mastocytosis only in adults without the D816V c-Kit mutation, or whose mutation status is unknown.
September 1, 2026 at 5:28 PM
Sometimes the test exists to keep you out. Gleevec is approved for aggressive systemic mastocytosis only in adults without the D816V c-Kit mutation, or whose mutation status is unknown.