When I was in the Lampson lab, doing lots of IF and looking for mitotic cells, I was always struck by how brightly some mitotic proteins would concentrate at midbodies
August 13, 2026 at 11:25 AM
When I was in the Lampson lab, doing lots of IF and looking for mitotic cells, I was always struck by how brightly some mitotic proteins would concentrate at midbodies
6/
Luckily, we can isolate the RNA contents of midbodies and compare them to whole cells. We and others had already found that specific RNAs are shuttled to the midbody. We started with one of the most enriched RNAs, Net1, and asked: how does it get there?
Luckily, we can isolate the RNA contents of midbodies and compare them to whole cells. We and others had already found that specific RNAs are shuttled to the midbody. We started with one of the most enriched RNAs, Net1, and asked: how does it get there?
August 12, 2026 at 3:44 PM
6/
Luckily, we can isolate the RNA contents of midbodies and compare them to whole cells. We and others had already found that specific RNAs are shuttled to the midbody. We started with one of the most enriched RNAs, Net1, and asked: how does it get there?
Luckily, we can isolate the RNA contents of midbodies and compare them to whole cells. We and others had already found that specific RNAs are shuttled to the midbody. We started with one of the most enriched RNAs, Net1, and asked: how does it get there?
Midbodies and ESCRTs really are amazing!
Cool new paper about ESCRT-III assembling around lagging DNA in the #midbody during cytokinetic #abscission of HeLa cells! New role for ESCRTs and Chmp1B! #midbodies are amazing.
Very proud to see this paper out. This is an incredible collaboration with the labs of Wes Sundquist and Adam Frost. @uofubiochem.bsky.social @kingslsm.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 22, 2026 at 4:12 PM
Midbodies and ESCRTs really are amazing!
Cool new paper about ESCRT-III assembling around lagging DNA in the #midbody during cytokinetic #abscission of HeLa cells! New role for ESCRTs and Chmp1B! #midbodies are amazing.
Very proud to see this paper out. This is an incredible collaboration with the labs of Wes Sundquist and Adam Frost. @uofubiochem.bsky.social @kingslsm.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ESCRT-III assembles around mis-segregated DNA to protect genome stability - Nature Structural & Molecular Biology
The authors show that persistent ultrafine DNA bridges become coated by membranes and the ESCRT-III proteins CHMP1B and IST1, which protect the genome within from damage.
www.nature.com
July 22, 2026 at 3:59 PM
Cool new paper about ESCRT-III assembling around lagging DNA in the #midbody during cytokinetic #abscission of HeLa cells! New role for ESCRTs and Chmp1B! #midbodies are amazing.
I’m excited to share that our pic of meiotic midbodies in wildtype and mos mutant oocytes made the cover @jcellsci.bsky.social! Congrats to @muhammad-haseeb.bsky.social and @giselacairobaza.bsky.social!
March 28, 2026 at 4:28 PM
I’m excited to share that our pic of meiotic midbodies in wildtype and mos mutant oocytes made the cover @jcellsci.bsky.social! Congrats to @muhammad-haseeb.bsky.social and @giselacairobaza.bsky.social!
Hello everyone !
I'm opening my commissions for a few ! I will not do fullbodies for this time but I'm still happy to discuss about it if you REALLY want one !
Backgrounds are not listed there but it can be discussed in DMs, depending on the complexity ^^
Thanks for your interest !
I'm opening my commissions for a few ! I will not do fullbodies for this time but I'm still happy to discuss about it if you REALLY want one !
Backgrounds are not listed there but it can be discussed in DMs, depending on the complexity ^^
Thanks for your interest !
November 17, 2025 at 4:44 PM
Hello everyone !
I'm opening my commissions for a few ! I will not do fullbodies for this time but I'm still happy to discuss about it if you REALLY want one !
Backgrounds are not listed there but it can be discussed in DMs, depending on the complexity ^^
Thanks for your interest !
I'm opening my commissions for a few ! I will not do fullbodies for this time but I'm still happy to discuss about it if you REALLY want one !
Backgrounds are not listed there but it can be discussed in DMs, depending on the complexity ^^
Thanks for your interest !
Another cool #abscission paper, showing ES cells regulate the duration of abscission depending on their potency stage. #devbio #cellbio #cytokinesis #midbodies 😀
Very excited that the lab's first paper is out! We showed that in stem cells, Aurora B controls abscission dynamics by regulating microtubules stability and MCAK recruitment. Very happy with this streamlined version of our 2024 preprint.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Aurora B controls microtubule stability to regulate abscission dynamics in stem cells
Mouse embryonic stem cells remain connected by bridges for hours after cell division.
In this paper, Kodba et al. show that a high Aurora B activity at the bridge leads
to microtubule stabilization. S...
www.cell.com
January 24, 2025 at 11:17 PM
Another cool #abscission paper, showing ES cells regulate the duration of abscission depending on their potency stage. #devbio #cellbio #cytokinesis #midbodies 😀
I am so sorry to hear this. I climbed Mt. Shasta with Steve in the late 1980s (at which time his adventures were legendary around UCSF), and later on had some great discussions about ESCRTs and midbodies.
January 17, 2025 at 4:53 PM
I am so sorry to hear this. I climbed Mt. Shasta with Steve in the late 1980s (at which time his adventures were legendary around UCSF), and later on had some great discussions about ESCRTs and midbodies.
Congrats to Katie Vaeth for her excellent talk at ASCB meeting on our work on RNA targeting to the Midbodies.
December 20, 2024 at 10:02 PM
Congrats to Katie Vaeth for her excellent talk at ASCB meeting on our work on RNA targeting to the Midbodies.
Thrilled our collaborative paper is out in NatureComms!
The meiotic midbody (mMB) has RNA and translation activity! #meiosis #midbody #RNA
Nothing is more thrilling in science than discovering something new and is broadly important, especially in development
www.nature.com/articles/s41...
The meiotic midbody (mMB) has RNA and translation activity! #meiosis #midbody #RNA
Nothing is more thrilling in science than discovering something new and is broadly important, especially in development
www.nature.com/articles/s41...
An oocyte meiotic midbody cap is required for developmental competence in mice - Nature Communicatio...
Midbodies form during cell division and play roles in cell function and fate. Here, the authors show that the meiotic midbody in mouse oocytes has a specialized cap structure required to retain nascen...
www.nature.com
November 16, 2023 at 9:15 PM
Thrilled our collaborative paper is out in NatureComms!
The meiotic midbody (mMB) has RNA and translation activity! #meiosis #midbody #RNA
Nothing is more thrilling in science than discovering something new and is broadly important, especially in development
www.nature.com/articles/s41...
The meiotic midbody (mMB) has RNA and translation activity! #meiosis #midbody #RNA
Nothing is more thrilling in science than discovering something new and is broadly important, especially in development
www.nature.com/articles/s41...
"Skop's lab and collaborators - analyzed the contents of midbodies—which form between the daughter cells during division—and tracked the interactions of the midbody remnants set free after cell division. Their results point to the midbody as a vehicle for the spread of cancer throughout the body."
Remnant of cell division could be responsible for spreading cancer
Once thought to be the trash can of the cell, a little bubble of cellular stuff called the midbody remnant is actually packing working genetic material with the power to change the fate of other cells...
phys.org
October 9, 2023 at 8:45 AM
"Skop's lab and collaborators - analyzed the contents of midbodies—which form between the daughter cells during division—and tracked the interactions of the midbody remnants set free after cell division. Their results point to the midbody as a vehicle for the spread of cancer throughout the body."