How do transcription factors bind DNA strongly, and in a switch like manner, while remaining sequence specific?
Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters.
www.science.org/doi/10.1126/...
Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters.
www.science.org/doi/10.1126/...
Nanoclustering of a plant transcription factor enables strong yet specific DNA binding
Transcription factor nanoclusters balance the DNA binding trade-off between weakly binding oligomers and nonspecific condensates.
www.science.org
July 25, 2026 at 10:47 AM
How do transcription factors bind DNA strongly, and in a switch like manner, while remaining sequence specific?
Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters.
www.science.org/doi/10.1126/...
Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters.
www.science.org/doi/10.1126/...
Plasma membrane nanoclusters help plants distinguish growth-promoting warmth from damaging heat.
Learn more in a new #SciencePerspective: https://scim.ag/4tXKR3m
Learn more in a new #SciencePerspective: https://scim.ag/4tXKR3m
Taking plant membrane temperatures
Plasma membrane nanoclusters help plants distinguish growth-promoting warmth from damaging heat
scim.ag
June 1, 2026 at 7:32 PM
Plasma membrane nanoclusters help plants distinguish growth-promoting warmth from damaging heat.
Learn more in a new #SciencePerspective: https://scim.ag/4tXKR3m
Learn more in a new #SciencePerspective: https://scim.ag/4tXKR3m
イリジウム
15-atom iridium nanoclusters stay stable 20 hours, outperform commercial catalysts
15-atom iridium nanoclusters stay stable 20 hours, outperform commercial catalysts
イリジウム
イリジウム
15-atom iridium nanoclusters stay stable 20 hours, outperform commercial catalysts
phys.org
June 20, 2026 at 4:10 AM
イリジウム
15-atom iridium nanoclusters stay stable 20 hours, outperform commercial catalysts
15-atom iridium nanoclusters stay stable 20 hours, outperform commercial catalysts
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
Climate warming poses increasing thermal challenges to plants, yet how plasma membrane biophysics contributes to heat adaptation remains poorly understood. In this work, we showed that the malectin-li...
www.science.org
May 21, 2026 at 7:54 PM
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Atomically Precise Cu12 Nanoclusters with Thermally Activated Delayed Fluorescence Properties | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Li, Wei, Shen, and co-workers @InorgChem #copper #Cu12 #nanoclusters #TADF
December 28, 2024 at 5:32 AM
Atomically Precise Cu12 Nanoclusters with Thermally Activated Delayed Fluorescence Properties | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Li, Wei, Shen, and co-workers @InorgChem #copper #Cu12 #nanoclusters #TADF
Mindblowing new study by @raflynn5.bsky.social @bostonchildrens.bsky.social, cell surface RNA-binding proteins form nanoclusters with #glycoRNA and mediate cell-penetrating peptide entry into cells 👏
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry
Mammalian cells present RNA-binding proteins on the cell surface that form clustered
domains containing glycoRNAs.
www.cell.com
February 27, 2025 at 11:58 PM
Mindblowing new study by @raflynn5.bsky.social @bostonchildrens.bsky.social, cell surface RNA-binding proteins form nanoclusters with #glycoRNA and mediate cell-penetrating peptide entry into cells 👏
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2...
doi.org/10.1002/smm2...
May 23, 2025 at 2:26 AM
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2...
doi.org/10.1002/smm2...
An RNA-binding protein on leukemia cells provides an effective target for treatment in mouse models, according to a paper in Nature Biotechnology. go.nature.com/44toSZ5 🧪
April 26, 2025 at 4:28 PM
An RNA-binding protein on leukemia cells provides an effective target for treatment in mouse models, according to a paper in Nature Biotechnology. go.nature.com/44toSZ5 🧪
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2...
doi.org/10.1002/smm2...
March 18, 2025 at 6:30 AM
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2...
doi.org/10.1002/smm2...
Assessing the photoluminescence of metal nanoclusters: The Individual versus the collective
@nanoclustering
sciencedirect.com/science/arti...
@nanoclustering
sciencedirect.com/science/arti...
March 28, 2025 at 1:02 AM
Assessing the photoluminescence of metal nanoclusters: The Individual versus the collective
@nanoclustering
sciencedirect.com/science/arti...
@nanoclustering
sciencedirect.com/science/arti...
💥RSC CNN Paper of the Week💥
JNH Reek,* University of Amsterdam
Metz et al, Chemical Science, 10.1039/D4SC06324D
M12L24 nanospheres as supramolecular templates for the controlled synthesis of Ir-nanoclusters...
#ChemSky #Science #ChemSci
JNH Reek,* University of Amsterdam
Metz et al, Chemical Science, 10.1039/D4SC06324D
M12L24 nanospheres as supramolecular templates for the controlled synthesis of Ir-nanoclusters...
#ChemSky #Science #ChemSci
M12L24 nanospheres as supramolecular templates for the controlled synthesis of Ir-nanoclusters and their use in the chemo-selective hydrogenation of nitro styrene
Controlled preparation of ultrafine metal nanoclusters (<2 nm) is challenging, yet important as the properties of these clusters are inherently linked to their size and local microenvironment. In the ...
pubs.rsc.org
November 19, 2024 at 9:46 AM
🌱 Atomically precise nanoclusters are transforming CO₂ elecroreduction! Unlocking powerful, selective & sustainable CO₂ conversion with metals & alloys! #CO2reduction #GreenChemistry #Nanoclusters doi.org/10.1039/D5NH...
July 14, 2025 at 4:42 AM
🌱 Atomically precise nanoclusters are transforming CO₂ elecroreduction! Unlocking powerful, selective & sustainable CO₂ conversion with metals & alloys! #CO2reduction #GreenChemistry #Nanoclusters doi.org/10.1039/D5NH...
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2.1317
doi.org/10.1002/smm2.1317
January 27, 2025 at 9:35 AM
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2.1317
doi.org/10.1002/smm2.1317
Ligand-bridged nanoassemblies boost the peroxidase-mimicking activity of gold nanoclusters
Ligand-bridged nanoassemblies boost the peroxidase-mimicking activity of gold nanoclusters
doi.org/10.1016/j.cc...
doi.org/10.1016/j.cc...
September 10, 2025 at 6:58 AM
Ligand-bridged nanoassemblies boost the peroxidase-mimicking activity of gold nanoclusters
Enhancing nanoparticles for cancer therapy 💊
The solubility of gold nanoclusters was improved & characterized in biological media:
pubmed.ncbi.nlm.nih.gov/39841626/
These nanoclusters showed good uptake in cancer cells:
pubmed.ncbi.nlm.nih.gov/39841867/
@uhnresearch.bsky.social
The solubility of gold nanoclusters was improved & characterized in biological media:
pubmed.ncbi.nlm.nih.gov/39841626/
These nanoclusters showed good uptake in cancer cells:
pubmed.ncbi.nlm.nih.gov/39841867/
@uhnresearch.bsky.social
January 27, 2025 at 3:39 PM
Enhancing nanoparticles for cancer therapy 💊
The solubility of gold nanoclusters was improved & characterized in biological media:
pubmed.ncbi.nlm.nih.gov/39841626/
These nanoclusters showed good uptake in cancer cells:
pubmed.ncbi.nlm.nih.gov/39841867/
@uhnresearch.bsky.social
The solubility of gold nanoclusters was improved & characterized in biological media:
pubmed.ncbi.nlm.nih.gov/39841626/
These nanoclusters showed good uptake in cancer cells:
pubmed.ncbi.nlm.nih.gov/39841867/
@uhnresearch.bsky.social
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
doi.org/10.1002/smm2...
doi.org/10.1002/smm2...
May 23, 2025 at 2:50 AM
Engineering Metal Nanoclusters at the Atomic Level for Effective Electrocatalysis
New #glycotime discovery from @raflynn5.bsky.social’s lab @bostonchildrens.bsky.social @harvard.edu, cell surface glycoRNA-RBP complexes organized by heparan sulfate PG nanoclusters that modulate VEGF signaling
www.nature.com/articles/s41...
www.nature.com/articles/s41...
GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling - Nature
Heparan sulfate proteoglycans facilitate the assembly of clusters of glycoRNAs and cell surface RNA-binding proteins, which negatively modulate VEGF-A signalling and angiogenesis.
www.nature.com
January 28, 2026 at 5:37 PM
New #glycotime discovery from @raflynn5.bsky.social’s lab @bostonchildrens.bsky.social @harvard.edu, cell surface glycoRNA-RBP complexes organized by heparan sulfate PG nanoclusters that modulate VEGF signaling
www.nature.com/articles/s41...
www.nature.com/articles/s41...
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance | Science www.science.org/doi/10.1126/...
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
Climate warming poses increasing thermal challenges to plants, yet how plasma membrane biophysics contributes to heat adaptation remains poorly understood. In this work, we showed that the malectin-li...
www.science.org
May 22, 2026 at 1:06 AM
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance | Science www.science.org/doi/10.1126/...
🌿🌡️FERONIA organizes sterol dependent nanoclusters as a thermal switch. Moderate heat activates FER via RALF34, recruiting stress signaling
Extreme heat triggers disassembly to prevent maladaptive responses #plantscience @science.org @abioticstress.bsky.social www.science.org/doi/10.1126/...
Extreme heat triggers disassembly to prevent maladaptive responses #plantscience @science.org @abioticstress.bsky.social www.science.org/doi/10.1126/...
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
Climate warming poses increasing thermal challenges to plants, yet how plasma membrane biophysics contributes to heat adaptation remains poorly understood. In this work, we showed that the malectin-li...
www.science.org
June 21, 2026 at 9:02 AM
🌿🌡️FERONIA organizes sterol dependent nanoclusters as a thermal switch. Moderate heat activates FER via RALF34, recruiting stress signaling
Extreme heat triggers disassembly to prevent maladaptive responses #plantscience @science.org @abioticstress.bsky.social www.science.org/doi/10.1126/...
Extreme heat triggers disassembly to prevent maladaptive responses #plantscience @science.org @abioticstress.bsky.social www.science.org/doi/10.1126/...
In this new paper in ACS Catalysis, XijunWang, @kaihangs.bsky.social, and Anyang Peng tackle some of the challenges in modeling supported amorphous metal oxide nanoclusters for methane activation. pubs.acs.org/doi/abs/10.1...
Computational Chemistry and Machine Learning-Assisted Screening of Supported Amorphous Metal Oxide Nanoclusters for Methane Activation
Activating the C–H bond in methane represents a cornerstone challenge in catalytic research. While several supported metal oxide nanoclusters (MeO-NCs) have shown promise for this reaction, their opti...
pubs.acs.org
December 14, 2024 at 7:41 PM
In this new paper in ACS Catalysis, XijunWang, @kaihangs.bsky.social, and Anyang Peng tackle some of the challenges in modeling supported amorphous metal oxide nanoclusters for methane activation. pubs.acs.org/doi/abs/10.1...
🥵#ClimateChange threatens global #agricultural productivity
🌡️Understanding how cells use membrane #biophysics to sense and decode #heat may help us to engineer thermotolerant #crops.
✅Find out more in this #FreeAccess #JIPB commentary.
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci
🌡️Understanding how cells use membrane #biophysics to sense and decode #heat may help us to engineer thermotolerant #crops.
✅Find out more in this #FreeAccess #JIPB commentary.
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci
Decoding heat through membrane nanoclusters in plants
This commentary interprets recent findings on how plants decode heat at the plasma membrane. By discussing FERONIA-mediated membrane nanoclusters, it highlights how receptor activation, lipid organiz...
doi.org
August 7, 2026 at 1:43 PM
🥵#ClimateChange threatens global #agricultural productivity
🌡️Understanding how cells use membrane #biophysics to sense and decode #heat may help us to engineer thermotolerant #crops.
✅Find out more in this #FreeAccess #JIPB commentary.
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci
🌡️Understanding how cells use membrane #biophysics to sense and decode #heat may help us to engineer thermotolerant #crops.
✅Find out more in this #FreeAccess #JIPB commentary.
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci
Do peptide–MHC I complexes cluster on the cell surface?
We counted them, one by one. Picomolar soluble TCRs + #DNAPAINT on primary human dendritic cells: pMHC I is monomeric. No nanoclusters.
What is regulated instead: surface density, and where complexes sit.
doi.org/10.1073/pnas.2615838123
We counted them, one by one. Picomolar soluble TCRs + #DNAPAINT on primary human dendritic cells: pMHC I is monomeric. No nanoclusters.
What is regulated instead: surface density, and where complexes sit.
doi.org/10.1073/pnas.2615838123
September 15, 2026 at 7:49 AM
Do peptide–MHC I complexes cluster on the cell surface?
We counted them, one by one. Picomolar soluble TCRs + #DNAPAINT on primary human dendritic cells: pMHC I is monomeric. No nanoclusters.
What is regulated instead: surface density, and where complexes sit.
doi.org/10.1073/pnas.2615838123
We counted them, one by one. Picomolar soluble TCRs + #DNAPAINT on primary human dendritic cells: pMHC I is monomeric. No nanoclusters.
What is regulated instead: surface density, and where complexes sit.
doi.org/10.1073/pnas.2615838123
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance | Science www.science.org/doi/10.1126/...
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
Climate warming poses increasing thermal challenges to plants, yet how plasma membrane biophysics contributes to heat adaptation remains poorly understood. In this work, we showed that the malectin-li...
www.science.org
May 21, 2026 at 11:53 PM
FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance | Science www.science.org/doi/10.1126/...
Tomorrow is Thursday, and that means a new issue! In the meantime, why not read about the connection between silver nanoclusters and watermelons? Spoiler, Cas is also involved 😎🧪 And subscribe to get more like this!
AI-powered watermelon chemistry: Silver nanoclusters & enzyme detection!
Innovative watermelon chemistry reveals silver nanoclusters for precise enzyme detection, showcasing cutting-edge molecular engineering at the nanoscale.
plentyofroom.beehiiv.com
May 14, 2025 at 7:05 PM
Tomorrow is Thursday, and that means a new issue! In the meantime, why not read about the connection between silver nanoclusters and watermelons? Spoiler, Cas is also involved 😎🧪 And subscribe to get more like this!
Recent research from Camelia Dutta and colleagues investigated using copper nanoclusters for delayed luminescence guided enhanced circularly polarised emission. Read the paper, for free, here:
doi.org/10.1039/D3SC...
#ChemSky
doi.org/10.1039/D3SC...
#ChemSky
Delayed luminescence guided enhanced circularly polarized emission in atomically precise copper nanoclusters
Metal nanoclusters, owing to their intriguing optical properties, have captivated research interest over the years. Of special interest have been chiral nanoclusters that display optical activity in the visible region of the electromagnetic spectrum. While the ground state chiral properties of metal nanoclus
doi.org
March 9, 2025 at 10:17 AM
Recent research from Camelia Dutta and colleagues investigated using copper nanoclusters for delayed luminescence guided enhanced circularly polarised emission. Read the paper, for free, here:
doi.org/10.1039/D3SC...
#ChemSky
doi.org/10.1039/D3SC...
#ChemSky