oh I forgot
imho: intranuclear medial hemorrhagic ophthalmoplegia
💀->this is a skull, it's where the brain lives
imho: intranuclear medial hemorrhagic ophthalmoplegia
💀->this is a skull, it's where the brain lives
December 8, 2024 at 6:35 PM
oh I forgot
imho: intranuclear medial hemorrhagic ophthalmoplegia
💀->this is a skull, it's where the brain lives
imho: intranuclear medial hemorrhagic ophthalmoplegia
💀->this is a skull, it's where the brain lives
New Case of the Month September 2026
A muscle biopsy for evaluation of progressive diplopia and external ophthalmoplegia by Drs. Lombardo, Anthony, and Punsoni of Brown University
A muscle biopsy for evaluation of progressive diplopia and external ophthalmoplegia by Drs. Lombardo, Anthony, and Punsoni of Brown University
September 29, 2026 at 1:10 AM
New Case of the Month September 2026
A muscle biopsy for evaluation of progressive diplopia and external ophthalmoplegia by Drs. Lombardo, Anthony, and Punsoni of Brown University
A muscle biopsy for evaluation of progressive diplopia and external ophthalmoplegia by Drs. Lombardo, Anthony, and Punsoni of Brown University
Clinical History:
A 76-year-old man had been followed by his ophthalmologist for worsening diplopia, exotropia, ptosis, and retinitis pigmentosa. The differential diagnosis was chronic progressive external ophthalmoplegia (CPEO), other mitochondrial disorder, or amyloidosis.
A 76-year-old man had been followed by his ophthalmologist for worsening diplopia, exotropia, ptosis, and retinitis pigmentosa. The differential diagnosis was chronic progressive external ophthalmoplegia (CPEO), other mitochondrial disorder, or amyloidosis.
September 29, 2026 at 1:10 AM
Clinical History:
A 76-year-old man had been followed by his ophthalmologist for worsening diplopia, exotropia, ptosis, and retinitis pigmentosa. The differential diagnosis was chronic progressive external ophthalmoplegia (CPEO), other mitochondrial disorder, or amyloidosis.
A 76-year-old man had been followed by his ophthalmologist for worsening diplopia, exotropia, ptosis, and retinitis pigmentosa. The differential diagnosis was chronic progressive external ophthalmoplegia (CPEO), other mitochondrial disorder, or amyloidosis.
Major medical breakthrough! 👁️
A first successful treatment for ophthalmoplegia, a rare eye disorder, has been made possible thanks to elamipretide, a therapeutic peptide targeting mitochondria—co-discovered by Dr. Peter W. Schiller, Research Professor Emeritus at the IRCM.
bit.ly/40xTDJx
A first successful treatment for ophthalmoplegia, a rare eye disorder, has been made possible thanks to elamipretide, a therapeutic peptide targeting mitochondria—co-discovered by Dr. Peter W. Schiller, Research Professor Emeritus at the IRCM.
bit.ly/40xTDJx
July 24, 2025 at 10:53 AM
Major medical breakthrough! 👁️
A first successful treatment for ophthalmoplegia, a rare eye disorder, has been made possible thanks to elamipretide, a therapeutic peptide targeting mitochondria—co-discovered by Dr. Peter W. Schiller, Research Professor Emeritus at the IRCM.
bit.ly/40xTDJx
A first successful treatment for ophthalmoplegia, a rare eye disorder, has been made possible thanks to elamipretide, a therapeutic peptide targeting mitochondria—co-discovered by Dr. Peter W. Schiller, Research Professor Emeritus at the IRCM.
bit.ly/40xTDJx
...... Barth syndrome, a rare genetic condition that affects the metabolism of lipids (fatty compounds)
... chronic progressive external ophthalmoplegia, a chronic, progressive condition that can cause weakness and an inability to move the eyes
... chronic progressive external ophthalmoplegia, a chronic, progressive condition that can cause weakness and an inability to move the eyes
August 30, 2025 at 5:11 PM
...... Barth syndrome, a rare genetic condition that affects the metabolism of lipids (fatty compounds)
... chronic progressive external ophthalmoplegia, a chronic, progressive condition that can cause weakness and an inability to move the eyes
... chronic progressive external ophthalmoplegia, a chronic, progressive condition that can cause weakness and an inability to move the eyes
/ Clinical features of THS
✅Ophthalmoplegia + periorbital pain / unilateral headaches
✅Most commonly involved CN: 3, 4, 6, 5
✅Key presentation: eye or head pain and double vision
The authors even made this nice symptom graphic!⬇️
✅Ophthalmoplegia + periorbital pain / unilateral headaches
✅Most commonly involved CN: 3, 4, 6, 5
✅Key presentation: eye or head pain and double vision
The authors even made this nice symptom graphic!⬇️
November 27, 2024 at 9:44 PM
/ Clinical features of THS
✅Ophthalmoplegia + periorbital pain / unilateral headaches
✅Most commonly involved CN: 3, 4, 6, 5
✅Key presentation: eye or head pain and double vision
The authors even made this nice symptom graphic!⬇️
✅Ophthalmoplegia + periorbital pain / unilateral headaches
✅Most commonly involved CN: 3, 4, 6, 5
✅Key presentation: eye or head pain and double vision
The authors even made this nice symptom graphic!⬇️
/ Tolosa-Hunt Syndrome (THS) has synonymous
✅ painful ophthalmoplegia
✅ recurrent ophthalmoplegia
✅ painful ophthalmoplegia
✅ recurrent ophthalmoplegia
November 27, 2024 at 9:44 PM
/ Tolosa-Hunt Syndrome (THS) has synonymous
✅ painful ophthalmoplegia
✅ recurrent ophthalmoplegia
✅ painful ophthalmoplegia
✅ recurrent ophthalmoplegia
Answer: mammillary bodies
paired round structures abutting midline
part of the diencephalon (Greek: across brain)
with Wernicke-Korsakoff syndrome: confabulation, ophthalmoplegia, ataxia
paired round structures abutting midline
part of the diencephalon (Greek: across brain)
with Wernicke-Korsakoff syndrome: confabulation, ophthalmoplegia, ataxia
December 15, 2024 at 1:43 AM
Answer: mammillary bodies
paired round structures abutting midline
part of the diencephalon (Greek: across brain)
with Wernicke-Korsakoff syndrome: confabulation, ophthalmoplegia, ataxia
paired round structures abutting midline
part of the diencephalon (Greek: across brain)
with Wernicke-Korsakoff syndrome: confabulation, ophthalmoplegia, ataxia
Internuclear ophthalmoplegia in Multiple Sclerosis youtube.com/shorts/FGqd8...
Internuclear ophthalmoplegia in Multiple Sclerosis
YouTube video by Dr. Brandon Beaber
youtube.com
May 9, 2025 at 5:53 PM
Internuclear ophthalmoplegia in Multiple Sclerosis youtube.com/shorts/FGqd8...
Protip: on exam, patients with myasthenia gravis may have weakness of the medial rectus that resembles an internuclear ophthalmoplegia. The way you distinguish this is by testing convergence (should be intact in pure INO).
April 10, 2026 at 10:36 AM
Protip: on exam, patients with myasthenia gravis may have weakness of the medial rectus that resembles an internuclear ophthalmoplegia. The way you distinguish this is by testing convergence (should be intact in pure INO).
UPFRONT Mystery Case #40: Alternating Bilateral Painful Ophthalmoplegia: Journal of Neuro-Ophthalmology
Article: bit.ly/JNO_UPFRONT40 or on bit.ly/JNO_Home#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #diplopia #ophthalmoplegia @DrewCareyMD @HopkinsMedicine
Article: bit.ly/JNO_UPFRONT40 or on bit.ly/JNO_Home#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #diplopia #ophthalmoplegia @DrewCareyMD @HopkinsMedicine
April 3, 2025 at 2:01 PM
UPFRONT Mystery Case #40: Alternating Bilateral Painful Ophthalmoplegia: Journal of Neuro-Ophthalmology
Article: bit.ly/JNO_UPFRONT40 or on bit.ly/JNO_Home#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #diplopia #ophthalmoplegia @DrewCareyMD @HopkinsMedicine
Article: bit.ly/JNO_UPFRONT40 or on bit.ly/JNO_Home#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #diplopia #ophthalmoplegia @DrewCareyMD @HopkinsMedicine
Chronic Progressive External Ophthalmoplegia Associated With the m.14484T.C Leber Hereditary Optic Neuropathy Mutation: Journal of Neuro-Ophthalmology
Article Link: bit.ly/JNO_LHON_CPEO
#eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #Genetic
Article Link: bit.ly/JNO_LHON_CPEO
#eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #Genetic
August 11, 2026 at 4:02 PM
Chronic Progressive External Ophthalmoplegia Associated With the m.14484T.C Leber Hereditary Optic Neuropathy Mutation: Journal of Neuro-Ophthalmology
Article Link: bit.ly/JNO_LHON_CPEO
#eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #Genetic
Article Link: bit.ly/JNO_LHON_CPEO
#eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #Genetic
NEW: A febrile patient presents with severe headache, periorbital swelling, proptosis, painful ophthalmoplegia and cranial nerve deficits following recent facial or sinus infection #SBA
What is the most likely diagnosis?
www.rcemlearning.co....
What is the most likely diagnosis?
www.rcemlearning.co....
May 28, 2026 at 11:59 AM
NEW: A febrile patient presents with severe headache, periorbital swelling, proptosis, painful ophthalmoplegia and cranial nerve deficits following recent facial or sinus infection #SBA
What is the most likely diagnosis?
www.rcemlearning.co....
What is the most likely diagnosis?
www.rcemlearning.co....
This work highlights the neccessity to explore tissue specific responses to disease and designing therapy according to it. Grateful for the support and contributions from ASWlab, collaborators and @awartiovaara.bsky.social
.
#MitochondrialDisease #MuscleBiology #PDK4 #Ophthalmoplegia
.
#MitochondrialDisease #MuscleBiology #PDK4 #Ophthalmoplegia
July 19, 2025 at 10:31 AM
This work highlights the neccessity to explore tissue specific responses to disease and designing therapy according to it. Grateful for the support and contributions from ASWlab, collaborators and @awartiovaara.bsky.social
.
#MitochondrialDisease #MuscleBiology #PDK4 #Ophthalmoplegia
.
#MitochondrialDisease #MuscleBiology #PDK4 #Ophthalmoplegia
Bickerstaff brainstem encephalitis (BBE) is a rare autoimmune disorder marked by sudden ataxia, ophthalmoplegia, and altered consciousness due to brainstem inflammation.
Learn more: eyewiki.org/Bickerstaff_...
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
Learn more: eyewiki.org/Bickerstaff_...
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
June 24, 2025 at 2:04 PM
Bickerstaff brainstem encephalitis (BBE) is a rare autoimmune disorder marked by sudden ataxia, ophthalmoplegia, and altered consciousness due to brainstem inflammation.
Learn more: eyewiki.org/Bickerstaff_...
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
Learn more: eyewiki.org/Bickerstaff_...
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
I don’t endorse this paper in general, it’s a product of its time, but the link has been reinforced a number of other times
X linked severe mental retardation, craniofacial dysmorphology, epilepsy, ophthalmoplegia, and cerebellar atrophy in a large South African kindred is localised to Xq24-q27
To date over 150 X linked mental retardation (XLMR) conditions have been documented. We describe a five generation South African family with XLMR, comprising 16 affected males and 10 carrier females. ...
pmc.ncbi.nlm.nih.gov
August 3, 2025 at 8:52 PM
I don’t endorse this paper in general, it’s a product of its time, but the link has been reinforced a number of other times
Ophthopedia Update: Man experiences bilateral proptosis, ophthalmoplegia after trauma: A 48-year-old man presented to the Lahey Eye Clinic as a new patient for care after recent head trauma while he was in another state.
He was experiencing constant headaches, he felt… #ophthalmology #eye #eyenews
He was experiencing constant headaches, he felt… #ophthalmology #eye #eyenews
Man experiences bilateral proptosis, ophthalmoplegia after trauma
A 48-year-old man presented to the Lahey Eye Clinic as a new patient for care after recent head trauma while he was in another state.
He was experiencing constant headaches, he felt his eyes looked “swollen and infected,” and vision was poor in the right…
dlvr.it
January 3, 2025 at 4:37 PM
Ophthopedia Update: Man experiences bilateral proptosis, ophthalmoplegia after trauma: A 48-year-old man presented to the Lahey Eye Clinic as a new patient for care after recent head trauma while he was in another state.
He was experiencing constant headaches, he felt… #ophthalmology #eye #eyenews
He was experiencing constant headaches, he felt… #ophthalmology #eye #eyenews
He also brought up what my neuro ophthalmologist did with the genetic testing and possible Chronic Progressive External Ophthalmoplegia. I basically told him how only the neuro opth thought that + MG and every other dr didn't and all I know is ivig works and I have a positive sfEMG so I have mg.
April 29, 2026 at 3:28 PM
He also brought up what my neuro ophthalmologist did with the genetic testing and possible Chronic Progressive External Ophthalmoplegia. I basically told him how only the neuro opth thought that + MG and every other dr didn't and all I know is ivig works and I have a positive sfEMG so I have mg.
Ophthalmoplegia Market Size, Share, Trends, Growth Till 2035 www.marketresearchfuture.com/reports/opht...
Ophthalmoplegia Market Size, Share & Growth Report 2035 | MRFR
The Ophthalmoplegia market is projected to grow from USD Billion 1.04 in 2024 to USD Billion 2.495 by 2035, at a CAGR of 8.28% during 2025-2035.
www.marketresearchfuture.com
September 16, 2026 at 7:19 AM
Ophthalmoplegia Market Size, Share, Trends, Growth Till 2035 www.marketresearchfuture.com/reports/opht...
Ophthalmoplegia Market Size, Share, Trends, Growth Till 2035 www.marketresearchfuture.com/reports/opht...
Ophthalmoplegia Market Size, Share & Growth Report 2035 | MRFR
The Ophthalmoplegia market is projected to grow from USD Billion 1.04 in 2024 to USD Billion 2.495 by 2035, at a CAGR of 8.28% during 2025-2035.
www.marketresearchfuture.com
September 8, 2026 at 1:40 PM
Ophthalmoplegia Market Size, Share, Trends, Growth Till 2035 www.marketresearchfuture.com/reports/opht...
An Early View: This narrative review integrates #clinical, familial, tissue-specific #heteroplasmy and functional evidence across the MT-TI variant spectrum. The authors sought to clarify the implications for variant interpretation and diagnosis.
🔗 Read here: onlinelibrary.wiley.com/doi/full/10....
🔗 Read here: onlinelibrary.wiley.com/doi/full/10....
September 7, 2026 at 11:53 AM
An Early View: This narrative review integrates #clinical, familial, tissue-specific #heteroplasmy and functional evidence across the MT-TI variant spectrum. The authors sought to clarify the implications for variant interpretation and diagnosis.
🔗 Read here: onlinelibrary.wiley.com/doi/full/10....
🔗 Read here: onlinelibrary.wiley.com/doi/full/10....
Ophthopedia Update: Necrotizing Granulomatous Orbital Inflammation Associated with Crohn Disease: A 30-year-old woman with Crohn disease presented with progressive bilateral periocular swelling, ptosis, conjunctival injection and chemosis, severe proptosis,… #Ophthalmology #ophthotwitter #eyecare
Necrotizing Granulomatous Orbital Inflammation Associated with Crohn Disease
A 30-year-old woman with Crohn disease presented with progressive bilateral periocular swelling, ptosis, conjunctival injection and chemosis, severe proptosis, ophthalmoplegia, and periorbital pain (A1–A3). Magnetic resonance imaging demonstrated diffuse infiltration of the lacrimal glands, orbital fat, extraocular muscles, and periorbital soft tissues (B). After orbital biopsy (C), histopathology (D) revealed granulomatous vasculitis with palisading epithelioid histiocytes (arrows), fibrinoid necrosis (asterisk), and necrotizing and nonnecrotizing granulomas in a background of fibrosis (not shown).
dlvr.it
September 7, 2026 at 2:27 AM
Ophthopedia Update: Necrotizing Granulomatous Orbital Inflammation Associated with Crohn Disease: A 30-year-old woman with Crohn disease presented with progressive bilateral periocular swelling, ptosis, conjunctival injection and chemosis, severe proptosis,… #Ophthalmology #ophthotwitter #eyecare
#CavernousSinus dural arteriovenous fistula can present with proptosis, conjunctival injection, and ophthalmoplegia; endovascular embolization achieved complete occlusion and rapid symptom resolution in this case. ja.ma/4q1mUHU
Cavernous Sinus Dural Arteriovenous Fistula With Ocular Congestion and Proptosis
This case report describes a 58-year-old man with a 10-day history of left eye redness, proptosis, blurred vision, and left-sided head pressure.
ja.ma
August 21, 2026 at 1:00 PM
#CavernousSinus dural arteriovenous fistula can present with proptosis, conjunctival injection, and ophthalmoplegia; endovascular embolization achieved complete occlusion and rapid symptom resolution in this case. ja.ma/4q1mUHU
Review this Wernicke-Korsakoff Syndrome flashcard to understand the effects of thiamine deficiency on the brain. Strengthen your USMLE Step 1 prep by recognizing classic clinical features, neuropathology, and risk factors.
U01.18.016 Wernicke-Korsakoff syndrome
Study this flashcard to understand the pathophysiology and clinical features of Wernicke-Korsakoff Syndrome. Identify how thiamine (vitamin B1) deficiency leads to Wernicke’s encephalopathy (ophthalmoplegia, ataxia, confusion) and Korsakoff psychosis (anterograde amnesia, confabulation) for USMLE Step 1.
mymedschool.org
October 29, 2025 at 10:18 PM
Review this Wernicke-Korsakoff Syndrome flashcard to understand the effects of thiamine deficiency on the brain. Strengthen your USMLE Step 1 prep by recognizing classic clinical features, neuropathology, and risk factors.