This study used three-dimensional pseudo-continuous arterial spin labeling (3D-PCASL) to investigate perfusion and volume differences among episodic migraine (EM), chronic migraine (CM), and normal control (NCs) groups. (🧵 2/9)

Hypothalamic subregional perfusion alterations in migraine: a 3D-PCASL study
▶️ Read Full Paper

📚 Source: Neurological research
👤 Creator: Yu Luo et al.
📅 Date: 2026-07-22

#MigrainePapertag/MigrainePaper" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#MigrainePaper #Migraine/hashtag/Migraine" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#Migraine #PubMed="/hashtag/PubMed" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#PubMed

Mechanical thrombectomy for ischemic stroke improves blood-brain barrier permeability and minimizes secondary injury! Our latest study used DP-pcASL to measure BBBP www.sciencedirect.com/science/arti...

The new diffusion-prepared pcASL sequence has so much potential for stroke! It can measure blood-brain barrier permeability in patients who had ischemic stroke and improve patient outcomes !

analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....

pmc.ncbi.nlm.nih.gov/articles/PMC...

On #WorldParkinsonsDay, I'd like to highlight “ASL as a Potential Biomarker in Imaging of #Neurodegenerative Disorders” by Prof. Sandhya Mangalore, et al. (Nat. Inst. of Mental Health and Neurosciences, India).

📄 marketing.webassets.siemens-healthineers.com/1a09d90d690b...

#NeuroSky #MRI #PETMRI

Open Access UCL Research: Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI
discovery.ucl.ac.uk/id/eprint/10...

2年前に立ち絵を描き始めてから何度も手直ししてついに自作Live2Dモデルが完成しました！5月5日にYouTube配信でお披露目します🐤

【告知】Live2Dお披露目は5月5日の21時から！#鴨川彰 #shorts youtube.com/shorts/pcASl...

배경: 편두통은 시상하부가 관여하는 흔한 신경학적 질환이지만, 특정 시상하부 하위 영역의 뇌혈류(CBF) 및 용적 변화는 아직 명확히 밝혀지지 않았다. 본 연구에서는 3차원 의사연속 동맥 스핀 라벨링(3D-PCASL) 기법을 사용하여 발작성 편두통(EM), 만성 편두통(CM), 정상 대조군(NCs) 간의 관류 및 부피 차이를 조사하였다. (🧵 1/5)

편두통에서 시상하부 하위 영역의 관류 변화: 3D-PCASL 연구
▶️ 논문읽기

📚 출처: Neurological research
👤 저자: Yu Luo et al.
📅 날짜: 2026년 07월 22일

🆔 PMID: 42482436
🔗 DOI: 10.1080/01616412.2026.2706103

#편두통논문g/%ED%8E%B8%EB%91%90%ED%86%B5%EB%85%BC%EB%AC%B8" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#편두통논문 #편두통hashtag/%ED%8E%B8%EB%91%90%ED%86%B5" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#편두통 #펍메드hashtag/%ED%8E%8D%EB%A9%94%EB%93%9C" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#펍메드

Letter to the Editor: "Cerebral Perfusion Features in Takayasu Arteritis: Insights From pCASL MRI"
https://pubmed.ncbi.nlm.nih.gov/40631412

Cerebral Perfusion Features in Takayasu Arteritis: Insights From pCASL MRI
https://pubmed.ncbi.nlm.nih.gov/40522064

I’ll give it a look too. At first glance I worry about the separate PCASL and BOLD runs. Attention & arousal effects could differ systematically.

www.sciencedirect.com/science/arti...

❔Could we use DP-pCASL to screen participants in clinical trials?
❔What drives this female “protection”? Hormones? Genetics? Lifestyle?
🔗 In @elife.bsky.social : elifesciences.org/articles/96155
#Research #Neurology #ClinicalTrials (4/12)

1️⃣ How does ageing affect BBB in males vs females? Study reveals that BBB function declines faster in males in specific brain regions.

Researchers analysed a diverse cohort of 186 cognitively normal individuals (ages 8–92) using DP-pCASL, a noninvasive, contrast-free #MRI (2/12)

Accelerated MCDW-pCASL Using Subspace Low-Rank Reconstruction for Quantification of BBB Water Exchange and Permeability https://www.medrxiv.org/content/10.64898/2026.07.13.26357046v1

Note that non-cognitive stimuli can cause CBF changes that easily surpass that level. E.g. midbrain CBF increases by 75–80% after levodopa + carbidopa (ASL), broadly consistent with results from human & NHP [15]O-water PET (and rodent 2DG).
(see Table 2 here: peerj.com/articles/1381/ )

Sneha Noble, Neelam Sinha, Vaanathi Sundareshan, Thomas Gregor Issac: Sex-Specific Vascular Score: A Novel Perfusion Biomarker from Supervoxel Analysis of 3D pCASL MRI https://arxiv.org/abs/2508.13173 https://arxiv.org/pdf/2508.13173 https://arxiv.org/html/2508.13173

Hemodynamic Responses in the White Matter (WM): Reduced Blood Flow in Deep WM During Hypercapnia Revealed by Multi-Delay pCASL in Healthy Young Adults https://www.biorxiv.org/content/10.64898/2026.06.01.729378v1

Alteration of Water Exchange Rates Following Focused Ultrasound-Mediated BBB Opening in the Dorsal Striatum of Non-Human Primates: A Diffusion-Prepared pCASL Study https://www.biorxiv.org/content/10.1101/2025.07.29.667530v1

SNR-Efficient Whole-Brain Pseudo-Continuous Arterial Spin Labeling Perfusion Imaging at 7 Tesla https://www.biorxiv.org/content/10.1101/2024.11.12.623276v1

High-resolution perfusion imaging in rodents using pCASL at 9.4 T https://www.biorxiv.org/content/10.1101/2024.03.07.583839v1

Hemodynamic Responses in the White Matter (WM): Reduced Blood Flow in Deep WM During Hypercapnia Revealed by Multi-Delay pCASL in Healthy Young Adults https://www.biorxiv.org/content/10.64898/2026.06.01.729378v1