Had a great time at #phages2025 last week! It was my first notable conference I went solo to. Thank you all for the many great talks and all the new people I met at all levels of research. I hope to be back again in a year or two with a project worthy of a talk!
August 14, 2025 at 2:23 PM
Had a great time at #phages2025 last week! It was my first notable conference I went solo to. Thank you all for the many great talks and all the new people I met at all levels of research. I hope to be back again in a year or two with a project worthy of a talk!
Had an amazing time at Phages! It was amazing to learn from very passionate people. 🔬🦠🧪 #phages2025
August 11, 2025 at 5:43 PM
Had an amazing time at Phages! It was amazing to learn from very passionate people. 🔬🦠🧪 #phages2025
Had a wonderful time at #phages2025. Cool venue, exciting science, and inspiring people!
August 8, 2025 at 10:39 PM
Had a wonderful time at #phages2025. Cool venue, exciting science, and inspiring people!
@femtokot.bsky.social
some call it thick skin
protection from cyclic storms
maybe pack your sponge
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@jbdsf.bsky.social lab
some call it thick skin
protection from cyclic storms
maybe pack your sponge
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@jbdsf.bsky.social lab
August 8, 2025 at 10:07 PM
@femtokot.bsky.social
some call it thick skin
protection from cyclic storms
maybe pack your sponge
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@jbdsf.bsky.social lab
some call it thick skin
protection from cyclic storms
maybe pack your sponge
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@jbdsf.bsky.social lab
Iana Fedorova: Acb2 sequesters nearly all known CBASS signaling molecules through two distinct binding pockets and therefore serves as a broad-spectrum “sponge” inhibitor of cGAS based innate immunity #phages2025 🦠
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides
Cyclic-oligonucleotide-based anti-phage signaling system (CBASS) is a common immune system that uses cyclic oligonucleotide signals to limit phage rep…
www.sciencedirect.com
August 8, 2025 at 10:02 PM
Iana Fedorova: Acb2 sequesters nearly all known CBASS signaling molecules through two distinct binding pockets and therefore serves as a broad-spectrum “sponge” inhibitor of cGAS based innate immunity #phages2025 🦠
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Emmanuel Allwell: #Xenorhabdus nematophila tailocins display common heterospecific killing but vary in conspecific killing; susceptibility profiles of strains to lysates were associated with O-antigen biosynthesis genes #phages2025 🦠
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Intraspecific bacterial competition mediated by rapidly diversifying tailocin and prophage loci
Signatures of selection in microbial genomes are often linked to biotic interactions, notably resistance to host immunity or bacteriophage attack. Here, we highlight the importance of competitive inte...
www.biorxiv.org
August 8, 2025 at 9:53 PM
Emmanuel Allwell: #Xenorhabdus nematophila tailocins display common heterospecific killing but vary in conspecific killing; susceptibility profiles of strains to lysates were associated with O-antigen biosynthesis genes #phages2025 🦠
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Emmanuel Allwell
homing sword disarmed
shields with doodads added on
match them up to know
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@hgblair.bsky.social lab
homing sword disarmed
shields with doodads added on
match them up to know
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@hgblair.bsky.social lab
August 8, 2025 at 9:50 PM
Emmanuel Allwell
homing sword disarmed
shields with doodads added on
match them up to know
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@hgblair.bsky.social lab
homing sword disarmed
shields with doodads added on
match them up to know
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@hgblair.bsky.social lab
Emma Wiesler
interpreting maps
squiggles, shadows, there’s the X
legend key conserved
#sciku 🧪🧬🔬🧫🦠 #Phages2025
interpreting maps
squiggles, shadows, there’s the X
legend key conserved
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 9:31 PM
Emma Wiesler
interpreting maps
squiggles, shadows, there’s the X
legend key conserved
#sciku 🧪🧬🔬🧫🦠 #Phages2025
interpreting maps
squiggles, shadows, there’s the X
legend key conserved
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Genevieve Dobihal
the windy path leads
virulence signature found
matters in hosts too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
the windy path leads
virulence signature found
matters in hosts too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 9:18 PM
Genevieve Dobihal
the windy path leads
virulence signature found
matters in hosts too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
the windy path leads
virulence signature found
matters in hosts too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@pseudo-mona.bsky.social
lil’ buddies poppin’
up, but evading ID
why make life hard? (fun!)
#sciku 🧪🧬🔬🧫🦠 #Phages2025
lil’ buddies poppin’
up, but evading ID
why make life hard? (fun!)
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 9:08 PM
@pseudo-mona.bsky.social
lil’ buddies poppin’
up, but evading ID
why make life hard? (fun!)
#sciku 🧪🧬🔬🧫🦠 #Phages2025
lil’ buddies poppin’
up, but evading ID
why make life hard? (fun!)
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Michael Cadigan
feed cookie monster
open can lid, stuff cookies
can bigger than thought
#sciku 🧪🧬🔬🧫🦠 #Phages2025
feed cookie monster
open can lid, stuff cookies
can bigger than thought
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 8:49 PM
Michael Cadigan
feed cookie monster
open can lid, stuff cookies
can bigger than thought
#sciku 🧪🧬🔬🧫🦠 #Phages2025
feed cookie monster
open can lid, stuff cookies
can bigger than thought
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Nasibeh Arabameri
organic divides
neighborhoods with character
some more violent
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@btsenglab.bsky.social lab
organic divides
neighborhoods with character
some more violent
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@btsenglab.bsky.social lab
Bluesky
tsenglab.bsky.social
August 8, 2025 at 8:32 PM
Nasibeh Arabameri
organic divides
neighborhoods with character
some more violent
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@btsenglab.bsky.social lab
organic divides
neighborhoods with character
some more violent
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@btsenglab.bsky.social lab
Vivian Zhang
an annoying “phly”
block with temporary wall
keeps gut balance tuned
#sciku 🧪🧬🔬🧫🦠 #Phages2025
an annoying “phly”
block with temporary wall
keeps gut balance tuned
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 8:24 PM
Vivian Zhang
an annoying “phly”
block with temporary wall
keeps gut balance tuned
#sciku 🧪🧬🔬🧫🦠 #Phages2025
an annoying “phly”
block with temporary wall
keeps gut balance tuned
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 8:00 PM
Jason Saba, Sternberg awardee
backflips landed right
trip all paralogs
domination set
#sciku 🧪🧬🔬🧫🦠 #Phages2025
doi.org/10.1126/scia...
doi.org/10.1038/s414...
doi.org/10.1038/s415...
backflips landed right
trip all paralogs
domination set
#sciku 🧪🧬🔬🧫🦠 #Phages2025
doi.org/10.1126/scia...
doi.org/10.1038/s414...
doi.org/10.1038/s415...
Single-cell analysis of multiple invertible promoters reveals differential inversion rates as a strong determinant of bacterial population heterogeneity
Bacteria orchestrate multiple promoter inversions to coordinate population diversity.
doi.org
August 8, 2025 at 5:08 PM
Jason Saba, Sternberg awardee
backflips landed right
trip all paralogs
domination set
#sciku 🧪🧬🔬🧫🦠 #Phages2025
doi.org/10.1126/scia...
doi.org/10.1038/s414...
doi.org/10.1038/s415...
backflips landed right
trip all paralogs
domination set
#sciku 🧪🧬🔬🧫🦠 #Phages2025
doi.org/10.1126/scia...
doi.org/10.1038/s414...
doi.org/10.1038/s415...
Jason Saba, Sternberg Awardee: #Bacteroides fragilis varies its cell surface with 8 capsular polysaccharide operons but only expresses 1 polysaccharide at a time using the combination of invertible promoters and a UpxY-UpxZ hierarchical regulatory program
#phages2025 🦠
www.nature.com/articles/s41...
#phages2025 🦠
www.nature.com/articles/s41...
Bacteroides expand the functional versatility of a conserved transcription factor and transcribed DNA to program capsule diversity - Nature Communications
Bacteroides strains have multiple operons for biosynthesis of diverse capsular polysaccharides, but most cells express only one operon at a time due to tight regulation of transcription elongation by ...
www.nature.com
August 8, 2025 at 5:03 PM
Jason Saba, Sternberg Awardee: #Bacteroides fragilis varies its cell surface with 8 capsular polysaccharide operons but only expresses 1 polysaccharide at a time using the combination of invertible promoters and a UpxY-UpxZ hierarchical regulatory program
#phages2025 🦠
www.nature.com/articles/s41...
#phages2025 🦠
www.nature.com/articles/s41...
August 8, 2025 at 4:46 PM
@kevinengland.bsky.social
some less P on G
synthesis goes down— but why?
indirect, or not
#sciku 🧪🧬🔬🧫🦠 #Phages2025
some less P on G
synthesis goes down— but why?
indirect, or not
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 4:32 PM
@kevinengland.bsky.social
some less P on G
synthesis goes down— but why?
indirect, or not
#sciku 🧪🧬🔬🧫🦠 #Phages2025
some less P on G
synthesis goes down— but why?
indirect, or not
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Rilee Zeinert
small protein active
tapped into regulation
sideways levels down
#sciku 🧪🧬🔬🧫🦠 #Phages2025
small protein active
tapped into regulation
sideways levels down
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 4:23 PM
Rilee Zeinert
small protein active
tapped into regulation
sideways levels down
#sciku 🧪🧬🔬🧫🦠 #Phages2025
small protein active
tapped into regulation
sideways levels down
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Khang Ho
pull favor away
phage co-opts host clamp for self
Mu transcribe away!
#sciku 🧪🧬🔬🧫🦠 #Phages2025
www.biorxiv.org/content/10.1....
pull favor away
phage co-opts host clamp for self
Mu transcribe away!
#sciku 🧪🧬🔬🧫🦠 #Phages2025
www.biorxiv.org/content/10.1....
Phage Mu Utilizes the Sliding Clamp for Late Gene Transcription
MuC, along with core RNAP and σ70, is required for transcription of late genes of phage Mu. We observed that overexpression of MuC is lethal in E. coli and that host replication was over-initiating un...
www.biorxiv.org
August 8, 2025 at 4:21 PM
Khang Ho
pull favor away
phage co-opts host clamp for self
Mu transcribe away!
#sciku 🧪🧬🔬🧫🦠 #Phages2025
www.biorxiv.org/content/10.1....
pull favor away
phage co-opts host clamp for self
Mu transcribe away!
#sciku 🧪🧬🔬🧫🦠 #Phages2025
www.biorxiv.org/content/10.1....
Ezaz Ahmad
pausing is normal
see more outside cell routine
marathon and sprints
#sciku 🧪🧬🔬🧫🦠 #Phages2025
pausing is normal
see more outside cell routine
marathon and sprints
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 3:02 PM
Ezaz Ahmad
pausing is normal
see more outside cell routine
marathon and sprints
#sciku 🧪🧬🔬🧫🦠 #Phages2025
pausing is normal
see more outside cell routine
marathon and sprints
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Divya Seerpatham
don’t fix if not broke
limit access by fixers
grounded during change
#sciku 🧪🧬🔬🧫🦠 #Phages2025
don’t fix if not broke
limit access by fixers
grounded during change
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 2:49 PM
Divya Seerpatham
don’t fix if not broke
limit access by fixers
grounded during change
#sciku 🧪🧬🔬🧫🦠 #Phages2025
don’t fix if not broke
limit access by fixers
grounded during change
#sciku 🧪🧬🔬🧫🦠 #Phages2025
Taylor Nye
best to take a NAPP:
CATNAPP, refreshed can ID
all partners bound there
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@scotthultgren.bsky.social lab
best to take a NAPP:
CATNAPP, refreshed can ID
all partners bound there
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@scotthultgren.bsky.social lab
August 8, 2025 at 2:41 PM
Taylor Nye
best to take a NAPP:
CATNAPP, refreshed can ID
all partners bound there
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@scotthultgren.bsky.social lab
best to take a NAPP:
CATNAPP, refreshed can ID
all partners bound there
#sciku 🧪🧬🔬🧫🦠 #Phages2025
@scotthultgren.bsky.social lab
Christine Baglio
streptomyces growth
balancing expansion out
sustain defense too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
hot off the press: doi.org/10.1038/s415...
streptomyces growth
balancing expansion out
sustain defense too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
hot off the press: doi.org/10.1038/s415...
Streptomyces uses both polar and dispersed cell wall synthesis during exploratory growth - Nature Microbiology
Streptomyces venezuelae requires MreB1-dependent dispersed peptidoglycan cell wall synthesis and DivIVA-mediated polar cell wall synthesis during its rapid exploratory growth phase.
doi.org
August 8, 2025 at 2:40 PM
Christine Baglio
streptomyces growth
balancing expansion out
sustain defense too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
hot off the press: doi.org/10.1038/s415...
streptomyces growth
balancing expansion out
sustain defense too
#sciku 🧪🧬🔬🧫🦠 #Phages2025
hot off the press: doi.org/10.1038/s415...
Marie Elliot
exposing repressed
compound clusters make new drugs
unique binding sites?
#sciku 🧪🧬🔬🧫🦠 #Phages2025
exposing repressed
compound clusters make new drugs
unique binding sites?
#sciku 🧪🧬🔬🧫🦠 #Phages2025
August 8, 2025 at 2:40 PM
Marie Elliot
exposing repressed
compound clusters make new drugs
unique binding sites?
#sciku 🧪🧬🔬🧫🦠 #Phages2025
exposing repressed
compound clusters make new drugs
unique binding sites?
#sciku 🧪🧬🔬🧫🦠 #Phages2025